CY1106800T1 - Μεθοδοι και συνθεσεις δια χρησιμοποιησεως μεταβολιτων τepφεναδινης εν συνδυασμω μετ’ αναστολεων λευκοτριενιου - Google Patents

Μεθοδοι και συνθεσεις δια χρησιμοποιησεως μεταβολιτων τepφεναδινης εν συνδυασμω μετ’ αναστολεων λευκοτριενιου

Info

Publication number
CY1106800T1
CY1106800T1 CY20061101264T CY061101264T CY1106800T1 CY 1106800 T1 CY1106800 T1 CY 1106800T1 CY 20061101264 T CY20061101264 T CY 20061101264T CY 061101264 T CY061101264 T CY 061101264T CY 1106800 T1 CY1106800 T1 CY 1106800T1
Authority
CY
Cyprus
Prior art keywords
methods
compositions
tefenadine
metabolites
combination
Prior art date
Application number
CY20061101264T
Other languages
English (en)
Inventor
Paul D. Rubin
Original Assignee
Sepracor Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc. filed Critical Sepracor Inc.
Publication of CY1106800T1 publication Critical patent/CY1106800T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Μέθοδοι και φαρμακευτικοί συνθέσεις δια χρησιμοποιήσεως μεταβολίτου τερφεναδίνης και αναστολέως λευκοτριενίου, δια την θεραπείαν ή πρόληψιν φλεγμονής ή αλλεργικών διαταραχών, όπως άσθματος, ή συμπτωμάτων αυτών. Επίσης περιλαμβάνονται μέθοδοι και συνθέσεις δια χρησιμοποιήσεως μεταβολίτου τερφεναδίνης, αναστολέως λευκοτριενίου, και αποσυμφορητικού, δια την θεραπείαν ή πρόληψιν φλεγμονής ή αλλεργικών διαταραχών, όπως άσθματος, ή συμπτωμάτων αυτών.
CY20061101264T 1998-04-14 2006-09-05 Μεθοδοι και συνθεσεις δια χρησιμοποιησεως μεταβολιτων τepφεναδινης εν συνδυασμω μετ’ αναστολεων λευκοτριενιου CY1106800T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/059,570 US6194431B1 (en) 1998-04-14 1998-04-14 Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
PCT/US1999/008077 WO1999052554A1 (en) 1998-04-14 1999-04-13 Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors

Publications (1)

Publication Number Publication Date
CY1106800T1 true CY1106800T1 (el) 2012-05-23

Family

ID=22023833

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061101264T CY1106800T1 (el) 1998-04-14 2006-09-05 Μεθοδοι και συνθεσεις δια χρησιμοποιησεως μεταβολιτων τepφεναδινης εν συνδυασμω μετ’ αναστολεων λευκοτριενιου

Country Status (21)

Country Link
US (4) US6194431B1 (el)
EP (2) EP1707216A1 (el)
JP (1) JP2002511426A (el)
KR (1) KR100686297B1 (el)
CN (2) CN1305385A (el)
AT (1) ATE328608T1 (el)
AU (1) AU763979B2 (el)
BR (1) BR9909641A (el)
CA (1) CA2328074C (el)
CY (1) CY1106800T1 (el)
DE (1) DE69931771T2 (el)
DK (1) DK1071463T3 (el)
ES (1) ES2260910T3 (el)
HU (1) HU228035B1 (el)
IL (2) IL138993A0 (el)
NO (1) NO20005147L (el)
NZ (1) NZ507762A (el)
PL (1) PL343526A1 (el)
PT (1) PT1071463E (el)
WO (1) WO1999052554A1 (el)
ZA (1) ZA200005553B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194431B1 (en) 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
US20020198246A1 (en) * 1998-09-30 2002-12-26 Ono Pharmaceutical Co., Ltd. Agent for preventing and/or treating sinusitis
DE10007203A1 (de) 2000-02-17 2001-08-23 Asta Medica Ag Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
US6440994B1 (en) 2000-03-29 2002-08-27 Richard J. Sanders, Jr. Method of treating acne
US20020198228A1 (en) * 2001-04-03 2002-12-26 Kaura Sita R. Composition and method for the treatment of respiratory desease
AU2003237253A1 (en) * 2002-05-29 2003-12-19 Aventis Pharmaceuticals Holdings Inc. Method of treating asthma using fexofenadine
US20040115647A1 (en) * 2002-12-12 2004-06-17 Paterson Thomas S. Apparatus and method for identifying biomarkers using a computer model
WO2009027852A2 (en) * 2007-08-28 2009-03-05 Agi Therapeutics, P.L.C. Methods and compositions for treating gastrointestinal conditions
WO2016011254A1 (en) * 2014-07-16 2016-01-21 Henry J. Legere Md, Pa Combinations of antihistamines and leukotriene antagonists and methods of use thereof

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US4254129A (en) 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
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Also Published As

Publication number Publication date
NZ507762A (en) 2003-09-26
CA2328074A1 (en) 1999-10-21
HUP0102239A3 (en) 2002-06-28
ES2260910T3 (es) 2006-11-01
EP1071463B1 (en) 2006-06-07
ZA200005553B (en) 2001-05-17
JP2002511426A (ja) 2002-04-16
DE69931771T2 (de) 2006-10-12
KR20010042655A (ko) 2001-05-25
KR100686297B1 (ko) 2007-02-23
IL138993A (en) 2011-01-31
NO20005147L (no) 2000-11-07
US20030083343A1 (en) 2003-05-01
EP1071463A1 (en) 2001-01-31
CN1305385A (zh) 2001-07-25
DK1071463T3 (da) 2006-09-25
US8404715B2 (en) 2013-03-26
HUP0102239A2 (hu) 2002-03-28
PT1071463E (pt) 2006-10-31
AU763979B2 (en) 2003-08-07
HU228035B1 (en) 2012-08-28
PL343526A1 (en) 2001-08-27
WO1999052554A1 (en) 1999-10-21
DE69931771D1 (de) 2006-07-20
EP1707216A1 (en) 2006-10-04
US20120149730A1 (en) 2012-06-14
IL138993A0 (en) 2001-11-25
AU3640999A (en) 1999-11-01
CA2328074C (en) 2012-02-21
CN1768749A (zh) 2006-05-10
NO20005147D0 (no) 2000-10-13
US6194431B1 (en) 2001-02-27
US6509353B1 (en) 2003-01-21
ATE328608T1 (de) 2006-06-15
BR9909641A (pt) 2000-12-19

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