BR9909427A - Processo para a preparação de um composto e composto - Google Patents
Processo para a preparação de um composto e compostoInfo
- Publication number
- BR9909427A BR9909427A BR9909427-4A BR9909427A BR9909427A BR 9909427 A BR9909427 A BR 9909427A BR 9909427 A BR9909427 A BR 9909427A BR 9909427 A BR9909427 A BR 9909427A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- preparation
- cetonitriles
- crf
- aryl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 102000012289 Corticotropin-Releasing Hormone Human genes 0.000 abstract 2
- 108010022152 Corticotropin-Releasing Hormone Proteins 0.000 abstract 2
- 239000000055 Corticotropin-Releasing Hormone Substances 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D201/00—Preparation, separation, purification or stabilisation of unsubstituted lactams
- C07D201/02—Preparation of lactams
- C07D201/08—Preparation of lactams from carboxylic acids or derivatives thereof, e.g. hydroxy carboxylic acids, lactones or nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Cephalosporin Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"PROCESSO PARA A PREPARAçãO DE UM COMPOSTO E COMPOSTO" A presente invenção se refere a processos para a produção de <244>-aril-<225>-cetonitrilas, que servem de intermediários de síntese na preparação de uma série de moléculas biologicamente importantes, tais como antagonistas receptores de fator de liberação de corticotropina (CRF).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8068098P | 1998-04-03 | 1998-04-03 | |
PCT/US1999/006822 WO1999051568A2 (en) | 1998-04-03 | 1999-03-29 | A CONVERGENT SYNTHESIS OF α-ARYL-β-KETONITRILES |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9909427A true BR9909427A (pt) | 2000-11-21 |
Family
ID=22158933
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9909427-4A BR9909427A (pt) | 1998-04-03 | 1999-03-29 | Processo para a preparação de um composto e composto |
Country Status (23)
Country | Link |
---|---|
US (1) | US6107508A (pt) |
EP (1) | EP1066250B1 (pt) |
JP (1) | JP2002510670A (pt) |
KR (1) | KR20010042401A (pt) |
CN (1) | CN1296473A (pt) |
AT (1) | ATE289990T1 (pt) |
AU (1) | AU3213599A (pt) |
BR (1) | BR9909427A (pt) |
CA (1) | CA2326846C (pt) |
CZ (1) | CZ20003519A3 (pt) |
DE (1) | DE69923958T2 (pt) |
DK (1) | DK1066250T3 (pt) |
EA (1) | EA200001017A1 (pt) |
EE (1) | EE200000580A (pt) |
ES (1) | ES2235472T3 (pt) |
HU (1) | HUP0101798A3 (pt) |
IL (1) | IL138501A0 (pt) |
NO (1) | NO20004956L (pt) |
PL (1) | PL343610A1 (pt) |
PT (1) | PT1066250E (pt) |
SK (1) | SK14432000A3 (pt) |
WO (1) | WO1999051568A2 (pt) |
ZA (1) | ZA200004654B (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6562965B1 (en) * | 2000-07-06 | 2003-05-13 | Bristol-Myers Squibb Pharma Company | Convergent synthesis of α-aryl-β-ketonitriles |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6296479A (ja) * | 1985-10-23 | 1987-05-02 | Shionogi & Co Ltd | ポリフルオロアルキルイソオキサゾリルアミン類 |
-
1999
- 1999-03-29 KR KR1020007010973A patent/KR20010042401A/ko not_active Application Discontinuation
- 1999-03-29 ES ES99914246T patent/ES2235472T3/es not_active Expired - Lifetime
- 1999-03-29 IL IL13850199A patent/IL138501A0/xx unknown
- 1999-03-29 EA EA200001017A patent/EA200001017A1/ru unknown
- 1999-03-29 AU AU32135/99A patent/AU3213599A/en not_active Abandoned
- 1999-03-29 HU HU0101798A patent/HUP0101798A3/hu unknown
- 1999-03-29 PL PL99343610A patent/PL343610A1/xx not_active Application Discontinuation
- 1999-03-29 BR BR9909427-4A patent/BR9909427A/pt not_active IP Right Cessation
- 1999-03-29 EP EP99914246A patent/EP1066250B1/en not_active Expired - Lifetime
- 1999-03-29 CZ CZ20003519A patent/CZ20003519A3/cs unknown
- 1999-03-29 EE EEP200000580A patent/EE200000580A/xx unknown
- 1999-03-29 SK SK1443-2000A patent/SK14432000A3/sk unknown
- 1999-03-29 PT PT99914246T patent/PT1066250E/pt unknown
- 1999-03-29 WO PCT/US1999/006822 patent/WO1999051568A2/en active IP Right Grant
- 1999-03-29 JP JP2000542290A patent/JP2002510670A/ja active Pending
- 1999-03-29 AT AT99914246T patent/ATE289990T1/de not_active IP Right Cessation
- 1999-03-29 DK DK99914246T patent/DK1066250T3/da active
- 1999-03-29 DE DE69923958T patent/DE69923958T2/de not_active Expired - Fee Related
- 1999-03-29 CA CA002326846A patent/CA2326846C/en not_active Expired - Fee Related
- 1999-03-29 CN CN99804854A patent/CN1296473A/zh active Pending
- 1999-03-31 US US09/282,508 patent/US6107508A/en not_active Expired - Lifetime
-
2000
- 2000-09-05 ZA ZA200004654A patent/ZA200004654B/en unknown
- 2000-10-02 NO NO20004956A patent/NO20004956L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EA200001017A1 (ru) | 2001-02-26 |
HUP0101798A2 (hu) | 2001-11-28 |
HUP0101798A3 (en) | 2003-03-28 |
PT1066250E (pt) | 2005-05-31 |
ZA200004654B (en) | 2001-12-24 |
JP2002510670A (ja) | 2002-04-09 |
PL343610A1 (en) | 2001-08-27 |
WO1999051568A2 (en) | 1999-10-14 |
KR20010042401A (ko) | 2001-05-25 |
DE69923958D1 (de) | 2005-04-07 |
CA2326846A1 (en) | 1999-10-14 |
EP1066250B1 (en) | 2005-03-02 |
NO20004956L (no) | 2000-11-01 |
SK14432000A3 (sk) | 2001-09-11 |
CZ20003519A3 (cs) | 2001-08-15 |
ES2235472T3 (es) | 2005-07-01 |
NO20004956D0 (no) | 2000-10-02 |
US6107508A (en) | 2000-08-22 |
WO1999051568A3 (en) | 1999-11-18 |
EP1066250A2 (en) | 2001-01-10 |
EE200000580A (et) | 2002-02-15 |
DE69923958T2 (de) | 2006-04-06 |
AU3213599A (en) | 1999-10-25 |
CA2326846C (en) | 2009-02-03 |
ATE289990T1 (de) | 2005-03-15 |
DK1066250T3 (da) | 2005-06-06 |
IL138501A0 (en) | 2001-10-31 |
CN1296473A (zh) | 2001-05-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4O,5O,6O, 7O E 8O ANUIDADES |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007. |