BR9908499A - Linhagens celulares embrionárias ousemelhantes a tronco produzidas portransplante nuclear de espécies cruzado - Google Patents
Linhagens celulares embrionárias ousemelhantes a tronco produzidas portransplante nuclear de espécies cruzadoInfo
- Publication number
- BR9908499A BR9908499A BR9908499-6A BR9908499A BR9908499A BR 9908499 A BR9908499 A BR 9908499A BR 9908499 A BR9908499 A BR 9908499A BR 9908499 A BR9908499 A BR 9908499A
- Authority
- BR
- Brazil
- Prior art keywords
- embryonic
- cells
- stem
- cell
- transplantation
- Prior art date
Links
- 238000010449 nuclear transplantation Methods 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 7
- 238000000034 method Methods 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 238000002054 transplantation Methods 0.000 abstract 2
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 230000022131 cell cycle Effects 0.000 abstract 1
- 230000024245 cell differentiation Effects 0.000 abstract 1
- 210000003855 cell nucleus Anatomy 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 230000018109 developmental process Effects 0.000 abstract 1
- 210000002308 embryonic cell Anatomy 0.000 abstract 1
- 210000001671 embryonic stem cell Anatomy 0.000 abstract 1
- 230000004077 genetic alteration Effects 0.000 abstract 1
- 231100000118 genetic alteration Toxicity 0.000 abstract 1
- 230000006801 homologous recombination Effects 0.000 abstract 1
- 238000002744 homologous recombination Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 210000000287 oocyte Anatomy 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2517/00—Cells related to new breeds of animals
- C12N2517/04—Cells produced using nuclear transfer
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Developmental Biology & Embryology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3294598A | 1998-03-02 | 1998-03-02 | |
| PCT/US1999/004608 WO1999045100A1 (en) | 1998-03-02 | 1999-03-02 | Embryonic or stem-like cell lines produced by cross-species nuclear transplantation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9908499A true BR9908499A (pt) | 2001-12-26 |
Family
ID=21867727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9908499-6A BR9908499A (pt) | 1998-03-02 | 1999-03-02 | Linhagens celulares embrionárias ousemelhantes a tronco produzidas portransplante nuclear de espécies cruzado |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1060243A4 (https=) |
| JP (1) | JP2002505100A (https=) |
| CN (1) | CN1299408A (https=) |
| AU (1) | AU759322B2 (https=) |
| BR (1) | BR9908499A (https=) |
| CA (1) | CA2323094A1 (https=) |
| IL (1) | IL138201A0 (https=) |
| NZ (1) | NZ506808A (https=) |
| WO (1) | WO1999045100A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ517609A (en) * | 1999-09-14 | 2004-02-27 | Univ Massachusetts | Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions |
| WO2001029206A1 (en) | 1999-10-15 | 2001-04-26 | Advanced Cell Technology, Inc. | Methods of producing differentiated progenitor cells and lineage-defective embryonic stem cells |
| AU784731B2 (en) * | 1999-12-20 | 2006-06-08 | University Of Massachusetts | Embryonic or stem-like cells produced by cross species nuclear transplantation |
| US6921665B2 (en) | 2000-11-27 | 2005-07-26 | Roslin Institute (Edinburgh) | Selective antibody targeting of undifferentiated stem cells |
| US6576464B2 (en) * | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
| AU2002250020A1 (en) * | 2001-02-02 | 2002-08-19 | Erik Forsberg | Method of cloning transgenic mammalian animals using pseudonuclei |
| CA2466198A1 (en) | 2001-11-06 | 2003-05-15 | Shanghai Second Medical University | Somatic cell derived embryonic stem cells and their differentiated progenies |
| JP2005508185A (ja) * | 2001-11-06 | 2005-03-31 | 上海第二医科大学 | ウサギの卵母細胞を用いる異種間体細胞核移植 |
| US20030204860A1 (en) * | 2002-04-01 | 2003-10-30 | David Melican | Method for selecting cell lines to be used for nuclear transfer in mammalian species |
| ES2705683T3 (es) * | 2002-12-16 | 2019-03-26 | Technion Res & Dev Foundation | Medio de cultivo de células madre pluripotentes |
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
| WO2013177228A1 (en) | 2012-05-22 | 2013-11-28 | Loma Linda University | Generation of integration/transgene-free stem cells |
| CN106661548B (zh) | 2014-05-28 | 2020-12-11 | 儿童医院医疗中心 | 用于经由定向分化将前体细胞转化为胃组织的方法和系统 |
| KR102729404B1 (ko) | 2016-11-04 | 2024-11-14 | 칠드런즈 호스피탈 메디칼 센터 | 간 유사 장기 조성물 및 이를 제조 및 사용하는 방법 |
| US12281334B2 (en) | 2017-04-14 | 2025-04-22 | Children's Hospital Medical Center | Multi donor stem cell compositions and methods of making same |
| EP3694603B1 (en) | 2017-10-10 | 2026-04-08 | Children's Hospital Medical Center | Esophageal tissue and/or organoid compositions and methods of making same |
| US12379372B2 (en) | 2017-12-21 | 2025-08-05 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| KR102887406B1 (ko) | 2018-07-26 | 2025-11-19 | 칠드런즈 호스피탈 메디칼 센터 | 간-담도-췌장 조직 및 이를 제조하는 방법 |
| AU2019339410A1 (en) | 2018-09-12 | 2021-04-15 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| WO2020160371A1 (en) | 2019-02-01 | 2020-08-06 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| WO2020243633A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| WO2020243613A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5905042A (en) * | 1996-04-01 | 1999-05-18 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Cultured inner cell mass cell lines derived from bovine or porcine embryos |
| CA2262817A1 (en) * | 1996-08-19 | 1998-02-26 | James Robl | Embryonic or stem-like cell lines produced by cross species nuclear transplantation |
| NZ337495A (en) * | 1997-03-06 | 2001-06-29 | Infigen Inc | Bovine primordial germ cells and their use in cloning |
| AU8587598A (en) * | 1997-07-26 | 1999-02-16 | Wisconsin Alumni Research Foundation | Trans-species nuclear transfer |
-
1999
- 1999-03-02 JP JP2000534632A patent/JP2002505100A/ja active Pending
- 1999-03-02 CA CA002323094A patent/CA2323094A1/en not_active Abandoned
- 1999-03-02 IL IL13820199A patent/IL138201A0/xx not_active IP Right Cessation
- 1999-03-02 BR BR9908499-6A patent/BR9908499A/pt not_active Application Discontinuation
- 1999-03-02 EP EP99911062A patent/EP1060243A4/en not_active Withdrawn
- 1999-03-02 AU AU29795/99A patent/AU759322B2/en not_active Ceased
- 1999-03-02 NZ NZ506808A patent/NZ506808A/en unknown
- 1999-03-02 WO PCT/US1999/004608 patent/WO1999045100A1/en not_active Ceased
- 1999-03-02 CN CN99805691A patent/CN1299408A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2323094A1 (en) | 1999-09-10 |
| WO1999045100A1 (en) | 1999-09-10 |
| AU759322B2 (en) | 2003-04-10 |
| CN1299408A (zh) | 2001-06-13 |
| NZ506808A (en) | 2003-12-19 |
| IL138201A0 (en) | 2001-10-31 |
| EP1060243A1 (en) | 2000-12-20 |
| AU2979599A (en) | 1999-09-20 |
| EP1060243A4 (en) | 2005-03-09 |
| JP2002505100A (ja) | 2002-02-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10 (VIII), 18 (III), 24 E 25 DA LPI. |
|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |