BR9903739A - Produção microbiana de actinol - Google Patents

Produção microbiana de actinol

Info

Publication number
BR9903739A
BR9903739A BR9903739-4A BR9903739A BR9903739A BR 9903739 A BR9903739 A BR 9903739A BR 9903739 A BR9903739 A BR 9903739A BR 9903739 A BR9903739 A BR 9903739A
Authority
BR
Brazil
Prior art keywords
trimethylcyclohexanone
hydroxy
trimethylcyclohexanedione
factor
actinol
Prior art date
Application number
BR9903739-4A
Other languages
English (en)
Inventor
Sakaya Shimizu
Masaru Wada
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR9903739A publication Critical patent/BR9903739A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/06—Arthrobacter
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: <B>"PRODUçãO MICROBIANA DE ACTINOL"<D>. Um processo para a fabricação de (4R,6R)-4-hidróxi-2,2,6-trimetilciclohexanodiona, que compreende por em contato o (6R)-2,2,6-trimetilciclohexanodiona com um microorganismo que é selecionado a partir do grupo que é composto por microorganismos dos gêneros Cellumonas, Corynebacterium, Planococcus e Arthrobacter e que é capaz da redução seletiva assimétrica do (4R,6R)-2,2,6-trimetilciclohexanodiona para o (4R,6R)-4-hidróxi-2,2,6-trimetilciclohexanona, e recuperando o (4R,6R)-4-hidróxi-2,2,6-trimetilciclohexanona, resultante a partir da mistura da reação. A redução seletiva assimétrica pode ser efetuada na presença de um co - fator tal como o dinucleotídio da nicotinamida adenina (NAD), fosfato do dinucleotídio da nicotinamida adenina (NADP), e o referido co - fator com glicose e desidrogenase de glicose (GDH), e/ou na presença de um tensoativo. O produto é utilizável para a síntese de carotenóides tais como a zeaxantina.
BR9903739-4A 1998-08-19 1999-08-18 Produção microbiana de actinol BR9903739A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98115564 1998-08-19

Publications (1)

Publication Number Publication Date
BR9903739A true BR9903739A (pt) 2000-10-17

Family

ID=8232480

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9903739-4A BR9903739A (pt) 1998-08-19 1999-08-18 Produção microbiana de actinol

Country Status (14)

Country Link
US (1) US6444460B1 (pt)
EP (1) EP0982406B1 (pt)
JP (1) JP3897489B2 (pt)
KR (1) KR100602296B1 (pt)
CN (1) CN1246466C (pt)
AT (1) ATE318925T1 (pt)
AU (1) AU753590B2 (pt)
BR (1) BR9903739A (pt)
CA (1) CA2280350A1 (pt)
DE (1) DE69930031T2 (pt)
ES (1) ES2259224T3 (pt)
ID (1) ID23839A (pt)
NO (1) NO319415B1 (pt)
TW (1) TWI229697B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000217572A (ja) 1999-02-01 2000-08-08 F Hoffmann La Roche Ag レボジオン還元酵素
CA2330023A1 (en) 2000-02-01 2001-08-01 F. Hoffmann-La Roche Ag Levodione reductase gene and use thereof
WO2004005526A1 (en) * 2002-07-04 2004-01-15 Dsm Ip Assets B.V. Process for producing phorenol
US20060121587A1 (en) * 2002-09-27 2006-06-08 Tatsuo Hoshino Process for actinol production from ketoisophorone
EP1931785A2 (en) * 2005-09-09 2008-06-18 DSMIP Assets B.V. Novel gene gms 01

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3988205A (en) 1974-08-21 1976-10-26 Hoffmann-La Roche Inc. Optically active cyclohexane derivatives
IT1041904B (it) * 1974-08-21 1980-01-10 Hoffmann La Roche Procedimento per la preparazione di derivati del cicloesano otticamente attivi
US5385833A (en) * 1992-02-26 1995-01-31 The Scripps Research Institute Pseudomonas sp. ATCC No. 49794 alcohol dehydrogenase

Also Published As

Publication number Publication date
EP0982406B1 (en) 2006-03-01
KR100602296B1 (ko) 2006-07-14
ID23839A (id) 2000-05-25
NO319415B1 (no) 2005-08-08
AU753590B2 (en) 2002-10-24
AU4455399A (en) 2000-03-09
NO993987L (no) 2000-02-21
DE69930031D1 (de) 2006-04-27
EP0982406A2 (en) 2000-03-01
ATE318925T1 (de) 2006-03-15
CA2280350A1 (en) 2000-02-19
ES2259224T3 (es) 2006-09-16
CN1254760A (zh) 2000-05-31
DE69930031T2 (de) 2006-09-28
JP2000069986A (ja) 2000-03-07
NO993987D0 (no) 1999-08-18
JP3897489B2 (ja) 2007-03-22
TWI229697B (en) 2005-03-21
US6444460B1 (en) 2002-09-03
EP0982406A3 (en) 2000-09-20
CN1246466C (zh) 2006-03-22
KR20000017373A (ko) 2000-03-25

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AO NAO RECOLHIMENTO DA 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 1986 DE 27/03/2009.