BR9815657A - Sistema transdermal não-invasivo para detectarum analisado - Google Patents

Sistema transdermal não-invasivo para detectarum analisado

Info

Publication number
BR9815657A
BR9815657A BR9815657-8A BR9815657A BR9815657A BR 9815657 A BR9815657 A BR 9815657A BR 9815657 A BR9815657 A BR 9815657A BR 9815657 A BR9815657 A BR 9815657A
Authority
BR
Brazil
Prior art keywords
analyte
present
chemistry component
interest
component
Prior art date
Application number
BR9815657-8A
Other languages
English (en)
Other versions
BR9815657B1 (pt
Inventor
Jack L Aronowitz
Joel R Mitchen
Original Assignee
Technical Chemicals & Products
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technical Chemicals & Products filed Critical Technical Chemicals & Products
Publication of BR9815657A publication Critical patent/BR9815657A/pt
Publication of BR9815657B1 publication Critical patent/BR9815657B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0035—Vaccination diagnosis other than by injuring the skin, e.g. allergy test patches
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/008—Interstitial fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

"SISTEMA TRANSDERMAL NãO-INVASIVO PARA DETECTARUM ANALISADO". A presente invenção se refere a sistemas emétosos transdermais não-invasivos para extração de analisado apartir de um fluido biológico dentro ou sob a pele, tal como umfluido intersticial, e detecção do analisado. Mais particularmente, apresente invenção relata um chumaço transdermal não-invasivocompreendido de um componente químico úmido e umcomponente químico seco. O componente químico úmido é ummeio de transferência líquido na forma de uma camada de gel paraa extração e transferência de líquido do analisado de interesse apartir do fluido biológico dentro ou sob a pele para o componentequímico seco. O componente químico seco é um super sensitivoou uma membrana condicionada que sustenta um sistema dereagente para interagir com o analisado de interesse para geraruma molécula indicadora; por exemplo, mudança de cor, paraconfirmar a detecção do analisado, os métodos e seus usos. Amolécula indicadora pode ser visualmente observada pelo usuárioindividual ou observada por um de componente interpenetraçãoeletrónico, tal como um espectrofotómetro de refletância paradetecção. Um analisado de interesse particular que pode serdetectado precisamente, qualitativa e quantitativamente de acordocom a presente invenção é a glucose. Os sistemas transdermaisnão-invasivos da presente invenção são de baixo custo eadequados para o uso conveniente por pessoas não-médicas.
BRPI9815657-8A 1997-09-11 1998-09-11 sistema transdermal não-invasivo para detectar um analisado. BR9815657B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/929,262 US6503198B1 (en) 1997-09-11 1997-09-11 Noninvasive transdermal systems for detecting an analyte obtained from or underneath skin and methods
PCT/US1998/019190 WO1999013336A1 (en) 1997-09-11 1998-09-11 Noninvasive transdermal systems for detecting analytes

Publications (2)

Publication Number Publication Date
BR9815657A true BR9815657A (pt) 2001-11-20
BR9815657B1 BR9815657B1 (pt) 2009-08-11

Family

ID=25457573

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9815657-8A BR9815657B1 (pt) 1997-09-11 1998-09-11 sistema transdermal não-invasivo para detectar um analisado.

Country Status (16)

Country Link
US (1) US6503198B1 (pt)
EP (1) EP1015887B1 (pt)
JP (2) JP2001516056A (pt)
KR (1) KR100666967B1 (pt)
CN (1) CN1144049C (pt)
AT (1) ATE478340T1 (pt)
AU (1) AU9485098A (pt)
BR (1) BR9815657B1 (pt)
CA (1) CA2303129A1 (pt)
DE (1) DE69841848D1 (pt)
ES (1) ES2348693T3 (pt)
IL (1) IL134992A0 (pt)
MX (1) MXPA00002489A (pt)
NO (1) NO20001126L (pt)
TW (1) TWI231862B (pt)
WO (1) WO1999013336A1 (pt)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8287483B2 (en) 1998-01-08 2012-10-16 Echo Therapeutics, Inc. Method and apparatus for enhancement of transdermal transport
US20060015058A1 (en) * 1998-01-08 2006-01-19 Kellogg Scott C Agents and methods for enhancement of transdermal transport
US7066884B2 (en) * 1998-01-08 2006-06-27 Sontra Medical, Inc. System, method, and device for non-invasive body fluid sampling and analysis
CA2335976A1 (en) 1998-06-24 1999-12-29 Transderm Diagnostics, Inc. Non-invasive transdermal detection of analytes
US20040171980A1 (en) 1998-12-18 2004-09-02 Sontra Medical, Inc. Method and apparatus for enhancement of transdermal transport
IL138788A0 (en) * 2000-09-29 2001-10-31 Falk Fish Method and kit for the transdermal determination of analyte concentration in blood
US6522903B1 (en) * 2000-10-19 2003-02-18 Medoptix, Inc. Glucose measurement utilizing non-invasive assessment methods
EP1262559A1 (en) * 2001-06-01 2002-12-04 SIRS-Lab GmbH Dermal patch for detecting lactate
US6501976B1 (en) 2001-06-12 2002-12-31 Lifescan, Inc. Percutaneous biological fluid sampling and analyte measurement devices and methods
US6793632B2 (en) 2001-06-12 2004-09-21 Lifescan, Inc. Percutaneous biological fluid constituent sampling and measurement devices and methods
US6721586B2 (en) 2001-06-12 2004-04-13 Lifescan, Inc. Percutaneous biological fluid sampling and analyte measurement devices and methods
US6875613B2 (en) 2001-06-12 2005-04-05 Lifescan, Inc. Biological fluid constituent sampling and measurement devices and methods
US6837988B2 (en) 2001-06-12 2005-01-04 Lifescan, Inc. Biological fluid sampling and analyte measurement devices and methods
US20030069482A1 (en) * 2001-10-09 2003-04-10 Workman Jerome James Sampling article for determining quantitative and qualitative drug transfer to skin
GB2400037A (en) * 2003-03-31 2004-10-06 Psimedica Ltd Device made of silicon and method for collecting mammary fluid
CA2522290A1 (en) * 2003-04-15 2004-10-28 Metgen, Inc. Medical device for monitoring blood phenylalanine levels
US20040225206A1 (en) * 2003-05-09 2004-11-11 Kouchnir Mikhail A. Non-invasive analyte measurement device having increased signal to noise ratios
CN1636505B (zh) * 2004-01-09 2011-11-09 希森美康株式会社 提取器具、提取装置和血糖值测量装置
US20050171413A1 (en) * 2004-02-04 2005-08-04 Medoptix, Inc. Integrated device for non-invasive analyte measurement
KR20070043768A (ko) * 2004-07-01 2007-04-25 비보메디칼 인코포레이티드 비-침습성 포도당 측정
US20070027383A1 (en) * 2004-07-01 2007-02-01 Peyser Thomas A Patches, systems, and methods for non-invasive glucose measurement
US20060024722A1 (en) 2004-07-30 2006-02-02 Mark Fischer-Colbrie Samples for detection of oncofetal fibronectin and uses thereof
US20060036138A1 (en) * 2004-08-06 2006-02-16 Adam Heller Devices and methods of screening for neoplastic and inflammatory disease
DE102004039570B4 (de) * 2004-08-14 2007-03-01 Lts Lohmann Therapie-Systeme Ag Überwachungssystem zum Sammeln und zur transdermalen Weiterdiffusion von Umweltkontaminantien enthaltender Luft und Verfahren hierzu
JP2008516641A (ja) * 2004-08-23 2008-05-22 リモート クリニカル ソリューションズ インコーポレイテッド 経口投与するための流体を変更するためのシステム及び方法
US8224414B2 (en) * 2004-10-28 2012-07-17 Echo Therapeutics, Inc. System and method for analyte sampling and analysis with hydrogel
JP4903414B2 (ja) * 2005-01-19 2012-03-28 シスメックス株式会社 分析物抽出カートリッジセットおよび分析方法
JP5688829B2 (ja) * 2005-11-11 2015-03-25 敏一 吉川 示差的な糖尿病の予知・診断方法および糖尿病予知・診断用キット
US7432069B2 (en) * 2005-12-05 2008-10-07 Sontra Medical Corporation Biocompatible chemically crosslinked hydrogels for glucose sensing
DK1962673T3 (da) * 2005-12-16 2011-02-07 Bayer Healthcare Llc Sensorindretning til transdermal analyse og fremgangsmåde til anvendelse deraf
DE102006026173A1 (de) * 2006-06-06 2007-12-20 Fachhochschule Südwestfalen Verfahren zur nichtinvasiven Diagnose von Diabetes
US8812071B2 (en) * 2007-03-07 2014-08-19 Echo Therapeutics, Inc. Transdermal analyte monitoring systems and methods for analyte detection
NZ580997A (en) * 2007-04-27 2011-08-26 Echo Therapeutics Inc Dermal abrasion device with feedback electrode to deliver data on skin thickness and removable abrasion heads
US20090147026A1 (en) * 2007-12-07 2009-06-11 Roche Diagnostics Operations, Inc. Graphic zoom functionality for a custom report
US10996218B2 (en) 2008-03-11 2021-05-04 Ournextbaby Llc Methods for chemotaxis / redox driven separation of X and Y chromosome bearing sperm and their insemination in gender specific menstrual cycles
US8759109B2 (en) 2008-03-11 2014-06-24 Urobiologics Llc Use of female mammal's urine for determination of fetal gender related characteristics
US20090259301A1 (en) * 2008-04-10 2009-10-15 Daniel Gelbart Detector for abnormal conditions inside body
JP4643768B2 (ja) * 2009-02-27 2011-03-02 シスメックス株式会社 生体内成分測定システム、組織液収集装置および生体内成分測定方法
JP5406646B2 (ja) * 2009-09-16 2014-02-05 シスメックス株式会社 組織液収集方法に用いる組織液収集キット及び組織液収集シート
FR2953717B1 (fr) * 2009-12-15 2014-06-27 Oreal Lingette avec emulsion comprenant un polymere epaississant et un ester d'acide laurique ou d'alcool laurylique
JP5419771B2 (ja) * 2010-03-26 2014-02-19 シスメックス株式会社 診断支援方法、診断支援システム及び診断支援装置
WO2012006617A2 (en) * 2010-07-09 2012-01-12 Methode Electronics, Inc. Optical analyte measurement
JP5792517B2 (ja) * 2011-06-02 2015-10-14 国立大学法人長岡技術科学大学 ストレスの評価方法
IL214096A (en) 2011-07-14 2016-02-29 Gideon Mor A system for detecting meconium in amniotic fluid
WO2013064313A1 (en) * 2011-10-31 2013-05-10 Sentec Ag A device for application of a sensor to a measurement site, a sensor head, a kit of an application device and sensor and use of an application device for optical measurements of physiological parameters
CN104144644B (zh) * 2012-03-01 2016-12-14 皇家飞利浦有限公司 用于确定气体的浓度的传感器
GB2499838A (en) * 2012-03-02 2013-09-04 Smartsensor Telemed Ltd Biological test device
ITUD20120114A1 (it) 2012-06-15 2013-12-16 Healthcare Global Initiative Fzc H Gi Dispositivo transdermico per la rilevazione fluorimetrica di un analita in un fluido biologico e apparecchiatura di analisi associata a detto dispositivo transdermico
WO2014026113A1 (en) * 2012-08-10 2014-02-13 The Research Foundation For The State University Of New York Near-infrared spectroscopy and optical reporter
US9778200B2 (en) * 2012-12-18 2017-10-03 Ixensor Co., Ltd. Method and apparatus for analyte measurement
JP5455135B1 (ja) * 2012-12-24 2014-03-26 卓 山口 血糖値ウォッチ装置
WO2016054079A1 (en) 2014-09-29 2016-04-07 Zyomed Corp. Systems and methods for blood glucose and other analyte detection and measurement using collision computing
TWI571238B (zh) * 2015-01-16 2017-02-21 亞洲大學 非侵入式代謝產物偵測裝置
US10746663B2 (en) * 2016-02-26 2020-08-18 DermaTec LLC Methods and apparatuses relating to dermal biochemical sensors
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
WO2018091439A1 (en) 2016-11-15 2018-05-24 Synework.Com Surface analysis patch
GB2559627A (en) * 2017-02-14 2018-08-15 Ndm Tech Ltd Device
US11986288B2 (en) 2017-03-06 2024-05-21 Medtronic Minimed, Inc. Colorometric sensor for the non-invasive screening of glucose in sweat in pre and type 2 diabetes
WO2018165180A1 (en) 2017-03-06 2018-09-13 Medtronic Minimed, Inc. Colorometric sensor for the non-invasive screening of glucose in sweat in pre and type 2 diabetes
CN111295577A (zh) * 2017-11-01 2020-06-16 小利兰·斯坦福大学托管委员会 分析物检测方法
US11860075B2 (en) 2017-11-28 2024-01-02 Organo Corporation Analyzing method and analyzing apparatus for urea
US11553861B1 (en) 2018-05-29 2023-01-17 My Salt and Sugar, LLC Apparatus to detect salt concentrations and glucose in bodily fluids
WO2020113183A1 (en) * 2018-11-29 2020-06-04 In Diagnostics, Inc. Single-use clinical spectrophotometer
CN114938978A (zh) * 2021-07-22 2022-08-26 上海微谱化工技术服务有限公司 一种皮肤表层物质的取样方法及其应用
CN118000726B (zh) * 2024-04-09 2024-07-23 之江实验室 一种基于比色法的穿戴式经皮二氧化碳检测装置及方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK8601218A (pt) * 1984-07-18 1986-03-17
US4960467A (en) * 1985-02-11 1990-10-02 The United States Of America As Represented By The Secretary Of The Army Dermal substance collection device
US4706676A (en) * 1985-02-11 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Dermal substance collection device
US4821733A (en) * 1987-08-18 1989-04-18 Dermal Systems International Transdermal detection system
US5465713A (en) * 1988-09-08 1995-11-14 Sudor Partners Energy-assisted transdermal collection patch for accelerated analyte collection and method of use
US5443080A (en) * 1993-12-22 1995-08-22 Americate Transtech, Inc. Integrated system for biological fluid constituent analysis
PT840597E (pt) * 1995-07-12 2004-02-27 Cygnus Therapeutic Systems Penso de hidrogel

Also Published As

Publication number Publication date
NO20001126D0 (no) 2000-03-06
CA2303129A1 (en) 1999-03-18
JP2001516056A (ja) 2001-09-25
JP4584338B2 (ja) 2010-11-17
MXPA00002489A (es) 2003-04-02
BR9815657B1 (pt) 2009-08-11
KR20010023876A (ko) 2001-03-26
ATE478340T1 (de) 2010-09-15
WO1999013336A1 (en) 1999-03-18
NO20001126L (no) 2000-04-27
IL134992A0 (en) 2001-05-20
US6503198B1 (en) 2003-01-07
WO1999013336A9 (en) 2000-07-20
ES2348693T3 (es) 2010-12-10
CN1144049C (zh) 2004-03-31
DE69841848D1 (de) 2010-09-30
KR100666967B1 (ko) 2007-01-12
EP1015887B1 (en) 2010-08-18
TWI231862B (en) 2005-05-01
AU9485098A (en) 1999-03-29
CN1301347A (zh) 2001-06-27
EP1015887A1 (en) 2000-07-05
JP2009195702A (ja) 2009-09-03

Similar Documents

Publication Publication Date Title
BR9815657A (pt) Sistema transdermal não-invasivo para detectarum analisado
PT1077634E (pt) Monitorizacao de substancias fisiologicas a analisar
US6267724B1 (en) Implantable diagnostic sensor
CO5271771A1 (es) Sistemas transdermicos no invasivos para detectar un analitico en un fluido biologico y metodos
DE60035174D1 (de) Invasives verfahren zur in vivo analytvermessung
DE69914319D1 (de) Signalverarbeitung zur messung von physiologischen analyten
ATE406834T1 (de) System zur überwachung der konzentration von analyten in körperflüssigkeiten
EP1260815A3 (en) Methods for automatically monitoring analyte concentration using minimally invasive devices
TWI256975B (en) Compositions containing a urea derivative dye for detecting an analyte and methods for using the same
DK1053043T3 (da) Opsamlingsenheder til transdermale prøveudtagningssystemer
PT1360933E (pt) Dispositivos para a recolha de amostras fisiologicas e metodos para utilizar os mesmos
WO2001038873A3 (en) Devices and methods for detecting analytes using electrosensor having capture reagent
PT1574858E (pt) Sistema de teste de analito para a determinacao da concentracao de um analito num fluido fisiologico ou aquoso.
NO20016364L (no) Fremgangsmåte og anordning for noninvasiv blodanalysemåling
AU2003243558A1 (en) Test strip for detection of analyte and methods of use
DE69119231D1 (de) Verfahren und vorrichtung zur bestimmung von chemischen spezies in körperflüssigkeit
DE69910007D1 (de) Vorrichtung zum vorhersagen von physiologischen messwerten
EP1319180A2 (en) Micro-invasive method for painless detection of analytes in extracellular space
Ciriacks et al. Monitoring D-serine dynamics in the rat brain using online microdialysis-capillary electrophoresis
Hirokawa et al. Simultaneous monitoring of inorganic cations, amines and amino acids in human sweat by capillary electrophoresis
Xiao et al. Microfluidic-based plasmonic microneedle biosensor for uric acid ultrasensitive monitoring
Sudha et al. Quantification of sweat urea in diabetes using electro-optical technique
RU2008129056A (ru) Устройство с двумя трансдермальными датчиками аналитов и способы его применения
NZ512768A (en) Diagnostic test to detect IV cytosolic phospholipase A2 (cPLA2)
ATE274183T1 (de) Diffusionskontrollierende sensorschicht

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Free format text: JACK L. ARONOWITZ (US)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 22/09/2009, OBSERVADAS AS CONDICOES LEGAIS.

B24B Patent annual fee: requirement for complementing annual fee

Free format text: CONFORME RESOLUCAO 124/06, O DEPOSITANTE DEVERA COMPLEMENTAR, DE ACORDO COM A TABELA VIGENTE, A RETRIBUICAO DA 12A ANUIDADE, REFERENTE A GUIA DE RECOLHIMENTO NO 92090583445-5.

B24D Patent annual fee: restoration after fee payment
B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time
B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)