CO5271771A1 - Sistemas transdermicos no invasivos para detectar un analitico en un fluido biologico y metodos - Google Patents

Sistemas transdermicos no invasivos para detectar un analitico en un fluido biologico y metodos

Info

Publication number
CO5271771A1
CO5271771A1 CO00018126A CO00018126A CO5271771A1 CO 5271771 A1 CO5271771 A1 CO 5271771A1 CO 00018126 A CO00018126 A CO 00018126A CO 00018126 A CO00018126 A CO 00018126A CO 5271771 A1 CO5271771 A1 CO 5271771A1
Authority
CO
Colombia
Prior art keywords
analyte
invasive
chemistry component
present
methods
Prior art date
Application number
CO00018126A
Other languages
English (en)
Inventor
Jack L Aronowitz
Joel R Mitchen
John Weiss
Irwin Weitman
Original Assignee
Technical Chemical And Product
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technical Chemical And Product filed Critical Technical Chemical And Product
Publication of CO5271771A1 publication Critical patent/CO5271771A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/8483Investigating reagent band

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a sistemas transdérmicos no invasivos y métodos para extracción de analitos de un fluido biológico dentro o debajo de la piel, tal como fluido intersticial, y detección del analito. Más especialmente, la presente invención se refiere a sistemas transdérmicos no invasivos que comprenden un parche no invasivo y un reflectómetro. Los parches transdérmicos no invasivos están compuestos por un componente de química húmeda y un componente de química seca. El componente de química húmeda es un medio de transferencia líquida en la forma de una capa de gel para la extracción y transferencia puenteada de líquidos del analito de interés del fluido biológico dentro o debajo de la piel al componente de química seca. El componente de química seca es una membrana supersensible y acondicionada que lleva un sistema reactivo para interactuar con el analito de interés para generar una molécula indicadora, por ej: cambio de color, para confirmar la detección del analito, y métodos para el uso de lo mismo. La molécula indicadora puede ser observada visualmente por el usuario u observada por un componente de interpretación electrónica, tal como un espectrofotómetro de reflectancia para detección. Una analito de interés en particular, que puede ser detectado de manera exacta, confiable y cuantitativa de acuerdo con la presente invención es glucosa. Los sistemas transdérmicos no invasivos de la presente invención son económicos e indicados para uso conveniente por parte de personal no médico. ...<EMI FILE="00018126_1" ID="1" IMF=JPEG > SOLICITUDES DE PATENTES DE INVENCIÓNORDENADAS PUBLICAR EN ENERO DE 2003 IMPORTANTESOLICITUDES DE PATENTE DE INVENCIÓN: a partir de la fecha de publicación de esta gaceta el solicitante cuenta con un plazo de seis (6) meses para pedir que se practique el examen de patentabilidad de la solicitud, anexando el recibo de pago de la tasa correspondiente a tal fin. De no procederse así la solicitud caerá en abandono (Art. 44 de la Decisión 486).
CO00018126A 1999-03-11 2000-03-13 Sistemas transdermicos no invasivos para detectar un analitico en un fluido biologico y metodos CO5271771A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/266,346 US7577469B1 (en) 1999-03-11 1999-03-11 Noninvasive transdermal systems for detecting an analyte in a biological fluid and methods

Publications (1)

Publication Number Publication Date
CO5271771A1 true CO5271771A1 (es) 2003-04-30

Family

ID=23014190

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00018126A CO5271771A1 (es) 1999-03-11 2000-03-13 Sistemas transdermicos no invasivos para detectar un analitico en un fluido biologico y metodos

Country Status (6)

Country Link
US (2) US7577469B1 (es)
AR (1) AR022908A1 (es)
AU (1) AU4005700A (es)
CO (1) CO5271771A1 (es)
TW (1) TW592664B (es)
WO (1) WO2000057177A1 (es)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1090301B1 (en) 1998-06-24 2002-07-31 Transderm Technologies LLC Non-invasive transdermal detection of analytes
US6424851B1 (en) * 1998-10-13 2002-07-23 Medoptix, Inc. Infrared ATR glucose measurement system (II)
US6522903B1 (en) 2000-10-19 2003-02-18 Medoptix, Inc. Glucose measurement utilizing non-invasive assessment methods
US6501976B1 (en) 2001-06-12 2002-12-31 Lifescan, Inc. Percutaneous biological fluid sampling and analyte measurement devices and methods
US6721586B2 (en) 2001-06-12 2004-04-13 Lifescan, Inc. Percutaneous biological fluid sampling and analyte measurement devices and methods
US6793632B2 (en) 2001-06-12 2004-09-21 Lifescan, Inc. Percutaneous biological fluid constituent sampling and measurement devices and methods
US6837988B2 (en) 2001-06-12 2005-01-04 Lifescan, Inc. Biological fluid sampling and analyte measurement devices and methods
US6875613B2 (en) 2001-06-12 2005-04-05 Lifescan, Inc. Biological fluid constituent sampling and measurement devices and methods
US6856125B2 (en) 2001-12-12 2005-02-15 Lifescan, Inc. Biosensor apparatus and method with sample type and volume detection
GB2397375A (en) * 2003-01-14 2004-07-21 Hypoguard Ltd Measuring analyte concentration in a fluid sample by illuminating the sample at two wavelengths
BRPI0409435A (pt) * 2003-04-15 2006-04-18 Sensors For Med & Science Inc dispositivo de circuito impresso com antena integrada e sistema de processamento de sensor implantável com antena de placa de circuito impresso integrada
US7569126B2 (en) 2004-06-18 2009-08-04 Roche Diagnostics Operations, Inc. System and method for quality assurance of a biosensor test strip
UY29721A1 (es) 2005-08-05 2007-03-30 Bayer Healthcare Llc Medidor con alarma de tiempo postprandial para efectuar determinaciones
BRPI0619833A2 (pt) * 2005-12-16 2011-10-18 Bayer Healthcare Llc conjunto de sensor de analisado transdérmico e métodos de uso do mesmo
US8219173B2 (en) 2008-09-30 2012-07-10 Abbott Diabetes Care Inc. Optimizing analyte sensor calibration
US8346335B2 (en) 2008-03-28 2013-01-01 Abbott Diabetes Care Inc. Analyte sensor calibration management
US7653425B2 (en) 2006-08-09 2010-01-26 Abbott Diabetes Care Inc. Method and system for providing calibration of an analyte sensor in an analyte monitoring system
US20080199894A1 (en) 2007-02-15 2008-08-21 Abbott Diabetes Care, Inc. Device and method for automatic data acquisition and/or detection
US8600681B2 (en) 2007-05-14 2013-12-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8239166B2 (en) 2007-05-14 2012-08-07 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
EP2206462A1 (en) 2009-01-13 2010-07-14 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO A non-invasive chemical sensor, a skin patch, a packaging material and a monitoring system using the same
FI4070729T3 (fi) 2009-08-31 2024-06-04 Abbott Diabetes Care Inc Lääkinnällisen laitteen näyttöjä
EP2325624A1 (de) * 2009-11-18 2011-05-25 F. Hoffmann-La Roche AG Verfahren und Vorrichtung zur Untersuchung einer Körperflüssigkeit
GB201008448D0 (en) 2010-05-20 2010-07-07 Univ Strathclyde Transdermal device
US20140307258A1 (en) * 2010-07-09 2014-10-16 Methode Electronics, Inc. Optical analyte measurement
CA2830551C (en) * 2011-03-25 2019-09-24 Hutchinson Technology Incorporated Systems and methods for measuring oxygenation
KR20140041890A (ko) * 2011-07-28 2014-04-04 메사추세츠 인스티튜트 오브 테크놀로지 고해상도 표면 측정 시스템 및 방법
WO2013023037A2 (en) * 2011-08-09 2013-02-14 Lemm Technologies, Llc Device and method for measuring an analyte under the nail
US8710993B2 (en) 2011-11-23 2014-04-29 Abbott Diabetes Care Inc. Mitigating single point failure of devices in an analyte monitoring system and methods thereof
ITUD20120114A1 (it) 2012-06-15 2013-12-16 Healthcare Global Initiative Fzc H Gi Dispositivo transdermico per la rilevazione fluorimetrica di un analita in un fluido biologico e apparecchiatura di analisi associata a detto dispositivo transdermico
US10132793B2 (en) 2012-08-30 2018-11-20 Abbott Diabetes Care Inc. Dropout detection in continuous analyte monitoring data during data excursions
EP2712544B1 (en) * 2012-09-28 2019-03-27 Cas Medical Systems, Inc. System and method for spectroscopic measurement of a characteristic of biological tissue
EP2967448A4 (en) 2013-03-13 2016-11-23 Church & Dwight Co Inc DIAGNOSTIC TEST EQUIPMENT WITH HORN FEEDBACK
AU2014241786A1 (en) * 2013-03-14 2015-10-29 Church & Dwight Co., Inc. Diagnostic test device with improved display
US9504405B2 (en) 2013-10-23 2016-11-29 Verily Life Sciences Llc Spatial modulation of magnetic particles in vasculature by external magnetic field
US10542918B2 (en) 2013-10-23 2020-01-28 Verily Life Sciences Llc Modulation of a response signal to distinguish between analyte and background signals
WO2015195540A1 (en) * 2014-06-16 2015-12-23 Guthrie Paul Joseph Methods, media, and apparatus for optimizing physical training based on real-time blood lactate monitoring
US9874554B1 (en) 2014-07-16 2018-01-23 Verily Life Sciences Llc Aptamer-based in vivo diagnostic system
US10034625B1 (en) 2014-09-22 2018-07-31 Verily Life Sciences Llc Aptamer-based analyte detection system and sensor
US9568432B2 (en) * 2014-09-26 2017-02-14 Intel Corporation Sensor apparatus to determine a value of a chemical parameter based on a color shade and methods thereof
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
TWI536020B (zh) * 2014-10-16 2016-06-01 國立清華大學 一種具檢測功能的試片及其所包含的檢測材料
WO2016164574A1 (en) * 2015-04-07 2016-10-13 Polymer Technology Systems, Inc. Systems and methods for artificial test strip controls
US10426387B2 (en) * 2015-06-25 2019-10-01 Fresenius Medical Care Holdings, Inc. Direct light differential measurement system
US20170242980A1 (en) * 2016-02-18 2017-08-24 Q Squared Solutions Holdings LLC Electronic writable memory devices for patient sample management
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
CN109788902A (zh) * 2016-07-06 2019-05-21 开米美景公司 用于检测水肿的系统和方法
TWI629482B (zh) * 2016-12-15 2018-07-11 聯華生技股份有限公司 Immunological lateral flow chromatography quantitative test piece for improving measurement accuracy
GB2559627A (en) * 2017-02-14 2018-08-15 Ndm Tech Ltd Device
WO2018165180A1 (en) * 2017-03-06 2018-09-13 Medtronic Minimed, Inc. Colorometric sensor for the non-invasive screening of glucose in sweat in pre and type 2 diabetes
US11986288B2 (en) 2017-03-06 2024-05-21 Medtronic Minimed, Inc. Colorometric sensor for the non-invasive screening of glucose in sweat in pre and type 2 diabetes
US20180355405A1 (en) * 2017-06-09 2018-12-13 Accessible Diagnostics, LLC System and Method for Determining Glucose Oxidase in an Analyte
WO2019221872A1 (en) * 2018-05-18 2019-11-21 Nanobio Systems Inc Collection and treatment of a biofluid sample
US10605741B2 (en) * 2018-06-28 2020-03-31 International Business Machines Corporation Accurate colorimetric based test strip reader system
KR102693439B1 (ko) * 2018-11-20 2024-08-07 삼성전자주식회사 스펙트럼 측정 장치, 스펙트럼의 광원 온도 변화 보정 방법, 농도 추정 장치 및 방법
US20210148812A1 (en) * 2019-11-18 2021-05-20 Steering Solutions Ip Holding Corporation Moisture detection system and method
CN113116295A (zh) * 2019-12-31 2021-07-16 裴璇 一种基于可见光调制的皮肤表面油脂检测系统与方法
US11618591B2 (en) * 2020-02-10 2023-04-04 The Boeing Company Composite laminate damage detection method using an in-situ thermal gradient and expansion differences across the damage
CN111272990A (zh) * 2020-02-27 2020-06-12 民康医疗科技(天津)有限公司 一种干化学检测试纸及制备工艺
WO2022256206A1 (en) * 2021-06-01 2022-12-08 The Regents Of The University Of California Quantitative particle agglutination assay using portable holographic imaging and deep learning

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910701A (en) 1973-07-30 1975-10-07 George R Henderson Method and apparatus for measuring light reflectance absorption and or transmission
DE2606991A1 (de) 1976-02-20 1977-08-25 Nils Dr Med Kaiser Geraet zur bestimmung des gehaltes von stoffwechselprodukten im blut
US4163950A (en) 1978-03-01 1979-08-07 Tektronix, Inc. Isolating differential amplifier
DE2934190A1 (de) 1979-08-23 1981-03-19 Müller, Gerhard, Prof. Dr.-Ing., 7080 Aalen Verfahren und vorrichtung zur molekuelspektroskopie, insbesondere zur bestimmung von stoffwechselprodukten
AU552675B2 (en) 1981-08-28 1986-06-12 Ligg Pty. Ltd. Reflectance meter
US4446232A (en) 1981-10-13 1984-05-01 Liotta Lance A Enzyme immunoassay with two-zoned device having bound antigens
US4723554A (en) 1984-04-27 1988-02-09 Massachusetts Institute Of Technology Skin pallor and blush monitor
EP0160768B1 (en) 1984-05-04 1989-05-03 Kurabo Industries Ltd. Spectrophotometric apparatus for the non-invasive determination of glucose in body tissues
GB8429211D0 (en) 1984-11-19 1984-12-27 Mit Peritronic Ltd Reflectometer
US4909256A (en) 1985-02-11 1990-03-20 The United States Of America, As Represented By The Secretary Of The Army Transdermal vapor collection method and apparatus
US4706676A (en) 1985-02-11 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Dermal substance collection device
US4960467A (en) 1985-02-11 1990-10-02 The United States Of America As Represented By The Secretary Of The Army Dermal substance collection device
US4627445A (en) 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
US4913150A (en) * 1986-08-18 1990-04-03 Physio-Control Corporation Method and apparatus for the automatic calibration of signals employed in oximetry
US4774192A (en) 1987-01-28 1988-09-27 Technimed Corporation A dry reagent delivery system with membrane having porosity gradient
US4821733A (en) 1987-08-18 1989-04-18 Dermal Systems International Transdermal detection system
US4781195A (en) 1987-12-02 1988-11-01 The Boc Group, Inc. Blood monitoring apparatus and methods with amplifier input dark current correction
US5203327A (en) 1988-09-08 1993-04-20 Sudor Partners Method and apparatus for determination of chemical species in body fluid
JPH0395435A (ja) 1989-09-08 1991-04-19 Terumo Corp 測定装置
EP0472963A3 (en) * 1990-08-27 1992-07-08 Sumitomo Electric Industries, Limited Light emitting diode for photosensor and photosensor using such light emitting diode
DE4027396A1 (de) 1990-08-30 1992-03-05 Unilever Nv Becherfoermige schale
EP0477417A1 (en) 1990-09-28 1992-04-01 Hewlett-Packard GmbH System for measuring a blood parameter and method therefor
US5174963A (en) 1991-01-07 1992-12-29 United Medical Manufacturing Company Blood glucose reflectance meter including a null prompting means and a device for providing a constant brightness light
US5179288A (en) 1991-09-30 1993-01-12 Ortho Pharmaceutical Corporation Apparatus and method for measuring a bodily constituent
US5477853A (en) * 1992-12-01 1995-12-26 Somanetics Corporation Temperature compensation method and apparatus for spectroscopic devices
US5443080A (en) 1993-12-22 1995-08-22 Americate Transtech, Inc. Integrated system for biological fluid constituent analysis
AU706662B2 (en) 1995-07-12 1999-06-17 Cygnus, Inc. Hydrogel patch
WO1999023479A1 (en) 1997-10-31 1999-05-14 Technical Chemicals & Products, Inc. Reflectometer

Also Published As

Publication number Publication date
US7577469B1 (en) 2009-08-18
TW592664B (en) 2004-06-21
AU4005700A (en) 2000-10-09
AR022908A1 (es) 2002-09-04
WO2000057177A1 (en) 2000-09-28
US20100049016A1 (en) 2010-02-25

Similar Documents

Publication Publication Date Title
CO5271771A1 (es) Sistemas transdermicos no invasivos para detectar un analitico en un fluido biologico y metodos
NO20001126D0 (no) Et ikke-angripende transdermalt system for Õ detektere analytter
Russell et al. A fluorescence-based glucose biosensor using concanavalin A and dextran encapsulated in a poly (ethylene glycol) hydrogel
de Belder et al. Preparation and properties of fluorescein-labelled hyaluronate
JP3600282B2 (ja) センサーの製造法及びそれにより製造されたセンサー
US6366793B1 (en) Minimally invasive methods for measuring analtes in vivo
TWI651075B (zh) 使用矽空位奈米鑽石之偵測方法及偵測裝置
Liao et al. Percutaneous fiber-optic sensor for chronic glucose monitoring in vivo
Goddard et al. Bioconjugation techniques for microfluidic biosensors
BR0210210A (pt) Sistema de medida biológico
EP1256797A3 (en) Optical concentration measurement in analyte detection devices
JP2008504881A5 (es)
WO2002022879A3 (en) Detection of microsatellite instability and its use in diagnosis of tumors
AU2002303444A1 (en) Detection of microsatellite instability and its use in diagnosis of tumors
WO2002035232A3 (en) Method for detecting ovarian cancer based on human kallikrein 6 (hk6)
Miao et al. Sensitive detection of glucose in human serum with oligonucleotide modified gold nanoparticles by using dynamic light scattering technique
Chen et al. Interaction behaviors between chitosan and hemoglobin
CN103728277A (zh) 用于结合有兴趣的标的物的装置与传感器及制造使用方法
Hanh et al. Penetration of compounds through human stratum corneum as studied by Fourier transform infrared photoacoustic spectroscopy
Bai et al. Identification of prostate cancer mRNA markers by averaged differential expression and their detection in biopsies, blood, and urine
Oriero et al. A potential enzyme-encapsulating, ultrafine fiber for phenol detection
JPWO2019183279A5 (es)
Prichard et al. The role of molecular staging in malignant melanoma
Kartha et al. Diagnosis at the molecular level: analytical laser spectroscopy for clinical applications
CN115343746A (zh) 一种测量工业辐照剂量二维分布的方法和胶片

Legal Events

Date Code Title Description
FA Application withdrawn