AR022908A1 - Sistemas no invasivos transdermicos para la deteccion del analito - Google Patents

Sistemas no invasivos transdermicos para la deteccion del analito

Info

Publication number
AR022908A1
AR022908A1 ARP000101084A ARP000101084A AR022908A1 AR 022908 A1 AR022908 A1 AR 022908A1 AR P000101084 A ARP000101084 A AR P000101084A AR P000101084 A ARP000101084 A AR P000101084A AR 022908 A1 AR022908 A1 AR 022908A1
Authority
AR
Argentina
Prior art keywords
analyte
chemical component
invasive transdermal
interest
color
Prior art date
Application number
ARP000101084A
Other languages
English (en)
Original Assignee
Technical Chemicals & Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technical Chemicals & Products Inc filed Critical Technical Chemicals & Products Inc
Publication of AR022908A1 publication Critical patent/AR022908A1/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente concierne sistemas no invasivos transdérmicos y métodos para la extraccion de analitos de un fluido biologico dentro o debajo de la piel, talcomo el fluido intersticial, y para la deteccion del analito. Más particularmente, la presentese relaciona con sistemas no invasivos transdérmicos quecomprenden un parche no invasivo transdérmico y un reflectometro, y métodos para detectar un analito de interés. Los parches no invasivos transdérmicoscomprenden un componente químico humedo yun componente químico seco. El componente químico humedo es un medio líquido de transferencia bajo la forma de unacapa de gel para la extraccion y la transferencia por puente líquido del analito de interés desde el fluido biologico dentro o debajode la piel hacia elcomponente químico seco. El componente químico seco es una membrana supersensible o condicionada que tiene un sistema de reactivos para interactuar con elanalito de interés y generar una molécula indicadora, por ejemplo, un cambiode co lor, para confirmar la deteccion del analito, y métodos para su uso. Lamolécula indicadora puede observarse a simple vista por el usuario individual u observarse por medio de un componente electronico de interpretacion, tal comounespectrofotometro d e reflectancia para la deteccion. Un analito particular de interés que puede detectarse con precision, de manera confiable y en unacantidad de acuerdo con la presente es la glucosa. Los sistemas no invasivos transdérmicos de lapresente son de bajo c osto y adecuados para el uso convenientepor parte de personal no médico. Los reflectometros incluyen una fuente de luz modulada para emitir luz con el objeto de iluminar la superficie blanco queposee un cierto color y unacierta sombra de color. La l uz que se refleja de la superficie blanco es detectada por un detector optico. La senal de salida deldetector optico es procesada y alimentada nuevamente en el detector optico para compensar cualquier desviacion causadapor la luz ambiental, por la t emperaturao por otros factores externos, y se amplifica en forma diferencial para generar una senal de salida indicativa del color y de la sombra en la superficie blanco
ARP000101084A 1999-03-11 2000-03-10 Sistemas no invasivos transdermicos para la deteccion del analito AR022908A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/266,346 US7577469B1 (en) 1999-03-11 1999-03-11 Noninvasive transdermal systems for detecting an analyte in a biological fluid and methods

Publications (1)

Publication Number Publication Date
AR022908A1 true AR022908A1 (es) 2002-09-04

Family

ID=23014190

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000101084A AR022908A1 (es) 1999-03-11 2000-03-10 Sistemas no invasivos transdermicos para la deteccion del analito

Country Status (6)

Country Link
US (2) US7577469B1 (es)
AR (1) AR022908A1 (es)
AU (1) AU4005700A (es)
CO (1) CO5271771A1 (es)
TW (1) TW592664B (es)
WO (1) WO2000057177A1 (es)

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Also Published As

Publication number Publication date
US20100049016A1 (en) 2010-02-25
US7577469B1 (en) 2009-08-18
WO2000057177A1 (en) 2000-09-28
TW592664B (en) 2004-06-21
CO5271771A1 (es) 2003-04-30
AU4005700A (en) 2000-10-09

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