BR9815457A - Kit de partida contendo composições de ácido nicotìnico e uso de ácido nicotìnico em uma formulação de liberação continuada - Google Patents

Kit de partida contendo composições de ácido nicotìnico e uso de ácido nicotìnico em uma formulação de liberação continuada

Info

Publication number
BR9815457A
BR9815457A BR9815457-5A BR9815457A BR9815457A BR 9815457 A BR9815457 A BR 9815457A BR 9815457 A BR9815457 A BR 9815457A BR 9815457 A BR9815457 A BR 9815457A
Authority
BR
Brazil
Prior art keywords
nicotinic acid
sustained release
release formulation
kit containing
starter kit
Prior art date
Application number
BR9815457-5A
Other languages
English (en)
Inventor
Eugenio A Cefali
Original Assignee
Kos Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25216509&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9815457(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kos Pharma Inc filed Critical Kos Pharma Inc
Publication of BR9815457A publication Critical patent/BR9815457A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Pyridine Compounds (AREA)

Abstract

"KIT DE PARTIDA CONTENDO COMPOSIçõES DE áCIDO NICOTìNICO E USO DE áCIDO NICOTìNICO EM UMA FORMULAçãO DE LIBERAçãO CONTINUADA". A presente invenção revela um kit de partida contendo ácido nicotínico em uma formulação de liberação continuada para titulação em pacientes com hiperlipidemia.
BR9815457-5A 1997-03-06 1998-03-06 Kit de partida contendo composições de ácido nicotìnico e uso de ácido nicotìnico em uma formulação de liberação continuada BR9815457A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/814,974 US6129930A (en) 1993-09-20 1997-03-06 Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
PCT/US1998/004578 WO1998039001A1 (en) 1997-03-06 1998-03-06 Starter kit containing nicotinic acid compositions

Publications (1)

Publication Number Publication Date
BR9815457A true BR9815457A (pt) 2001-10-16

Family

ID=25216509

Family Applications (2)

Application Number Title Priority Date Filing Date
BR9815454-0A BR9815454A (pt) 1997-03-06 1998-03-06 Composições de ácido nicotìnico para tratamento de hiperlipidemia e métodos relacionados às mesmas
BR9815457-5A BR9815457A (pt) 1997-03-06 1998-03-06 Kit de partida contendo composições de ácido nicotìnico e uso de ácido nicotìnico em uma formulação de liberação continuada

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR9815454-0A BR9815454A (pt) 1997-03-06 1998-03-06 Composições de ácido nicotìnico para tratamento de hiperlipidemia e métodos relacionados às mesmas

Country Status (11)

Country Link
US (2) US6129930A (pt)
EP (2) EP0969837A1 (pt)
AT (1) ATE289197T1 (pt)
AU (2) AU6348198A (pt)
BR (2) BR9815454A (pt)
CA (3) CA2283322C (pt)
DE (1) DE69829042T2 (pt)
ES (1) ES2234100T3 (pt)
FI (2) FI119910B (pt)
NO (2) NO994248L (pt)
WO (2) WO1998039002A1 (pt)

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US20060263428A1 (en) * 1993-09-20 2006-11-23 Eugenio Cefali Methods for treating hyperlipidemia with intermediate release nicotinic acid compositions having unique biopharmaceutical characteristics
EP2319513A1 (en) * 1993-09-20 2011-05-11 Abbott Respiratory LLC Nicotinic acid compositons for treating hyperlipidemia and related methods therefor
US6129930A (en) * 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
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US20010006644A1 (en) * 1997-07-31 2001-07-05 David J. Bova Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
BR9815548A (pt) * 1997-07-31 2000-11-07 Kos Pharma Inc Composição farmacêutica para administração em dose única diária para alteração de lipìdios num indivìduo sem causar hepatotoxicidade induzida por drogas, miopatia ou rabdomiólise, comprimido revestido para administração oral e método para administração de dita composição
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CA2569776A1 (en) * 2006-02-17 2007-08-17 Kos Life Sciences, Inc. Low flush niacin formulation
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JP2009529057A (ja) * 2006-03-08 2009-08-13 コートリア・コーポレーシヨン Ｃｏｘ−関連胃損傷を予防するための非−選択的ｃｏｘ阻害剤との組み合わせ療法
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WO2008100249A1 (en) * 2007-02-13 2008-08-21 Kos Life Sciences, Inc. Low flush niacin formulation
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CA2932504A1 (en) 2013-12-13 2015-06-18 Conaris Research Institute Ag A pharmaceutical composition containing combinations of nicotinamide and 5-aminosalicylic acid for beneficially influencing the intestinal microbiota and/or treating gastrointestinal inflammation
US10888555B2 (en) * 2013-12-13 2021-01-12 Conaris Research Institute Ag Pharmaceutical composition containing nicotinic acid and/or nicotinamide for beneficially influencing blood lipid levels by modifying the intestinal microbiota

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US7011848B1 (en) 2006-03-14
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