BR9815325A - Heteroaril, aminoguanidinas e alcóxiguanidinas eseu uso como inibidores da protease - Google Patents
Heteroaril, aminoguanidinas e alcóxiguanidinas eseu uso como inibidores da proteaseInfo
- Publication number
- BR9815325A BR9815325A BR9815325-0A BR9815325A BR9815325A BR 9815325 A BR9815325 A BR 9815325A BR 9815325 A BR9815325 A BR 9815325A BR 9815325 A BR9815325 A BR 9815325A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- blood
- inhibiting
- formation
- thrombin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6647597P | 1997-11-26 | 1997-11-26 | |
US6732497P | 1997-12-05 | 1997-12-05 | |
US7910798P | 1998-03-23 | 1998-03-23 | |
PCT/US1998/025185 WO1999026926A1 (en) | 1997-11-26 | 1998-11-25 | Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9815325A true BR9815325A (pt) | 2001-12-26 |
Family
ID=27370979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9815325-0A BR9815325A (pt) | 1997-11-26 | 1998-11-25 | Heteroaril, aminoguanidinas e alcóxiguanidinas eseu uso como inibidores da protease |
Country Status (14)
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL340560A1 (en) * | 1997-11-26 | 2001-02-12 | Dimensional Pharmaceuticals 3 | Heteroaryl aminoguanidines and alkoxyguanidines and their application as protease inhibitors |
US6417161B1 (en) * | 1998-04-24 | 2002-07-09 | 3-Dimensional Pharmaceuticals, Inc. | Amino acid amidinohydrazones, alkoxyguanidines and aminoguanidines as protease inhibitors |
DE69926884T2 (de) * | 1998-06-11 | 2006-06-14 | Johnson & Johnson Pharm Res | Pyrazine protease inhibitore |
WO2000069826A1 (en) * | 1999-05-19 | 2000-11-23 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade |
US6750342B1 (en) | 1999-05-19 | 2004-06-15 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade |
US6716838B1 (en) | 1999-05-19 | 2004-04-06 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents |
US6906068B1 (en) | 1999-05-19 | 2005-06-14 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl 1,2,4 - triazinones useful as anticoagulants |
US7015230B1 (en) | 1999-05-19 | 2006-03-21 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade |
US6664255B1 (en) | 1999-05-19 | 2003-12-16 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade |
US6458952B1 (en) * | 1999-05-19 | 2002-10-01 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade |
US6653316B1 (en) * | 1999-05-19 | 2003-11-25 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade |
US6908919B2 (en) * | 1999-05-19 | 2005-06-21 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade |
US6867217B1 (en) | 1999-05-19 | 2005-03-15 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade |
WO2000073302A1 (en) | 1999-05-27 | 2000-12-07 | 3-Dimensional Pharmaceuticals, Inc. | Oxazaheterocycles as protease inhibitors |
WO2001004117A1 (en) * | 1999-07-09 | 2001-01-18 | 3-Dimensional Pharmaceuticals, Inc. | Heteroaryl protease inhibitors and diagnostic imaging agents |
US6469029B1 (en) * | 1999-09-13 | 2002-10-22 | 3-Dimensional Pharmaceuticals, Inc. | Azacycloalkanone serine protease inhibitors |
EP1127884A1 (en) * | 2000-02-26 | 2001-08-29 | Aventis Pharma Deutschland GmbH | Novel malonic acid derivatives, processes for their preparation, their use as inhibitor of factor XA activity and pharmaceutical compositions containing them |
AU2001243598A1 (en) | 2000-03-13 | 2001-09-24 | Pharmacia Corporation | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade |
AU2001249870A1 (en) | 2000-04-05 | 2001-10-23 | Pharmacia Corporation | Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade |
AU2001251315A1 (en) * | 2000-04-05 | 2001-10-23 | Pharmacia Corporation | Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the coagulation cascade |
JP2004501077A (ja) * | 2000-04-17 | 2004-01-15 | ファルマシア・コーポレーション | 凝固カスケードの選択的阻害に有用な多環式アリールおよびヘテロアリール置換1,4−キノン |
AU2001217827A1 (en) * | 2000-05-18 | 2001-11-26 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade |
JP2004504305A (ja) | 2000-07-17 | 2004-02-12 | 3−ディメンショナル ファーマシューティカルズ, インコーポレイテッド | プロテアーゼインヒビターとしての環状オキシグアニジンピラジノン |
EP1307432A1 (en) * | 2000-08-04 | 2003-05-07 | 3-Dimensional Pharmaceuticals, Inc. | Cyclic oxyguanidine protease inhibitors |
US20020037897A1 (en) * | 2000-08-07 | 2002-03-28 | 3-Dimensional Pharmaceuticals, Inc. | Tetrahydroisoquinoline-3-carboxylic acid alkoxyguanidines as integrin antagonists |
US6486174B2 (en) | 2000-08-07 | 2002-11-26 | 3-Dimensional Pharmaceuticals, Inc. | Tetrahydroisoquinoline-3-carboxylic acid alkoxyguanidines as integrin antagonists |
UA75093C2 (en) | 2000-10-06 | 2006-03-15 | Dimensional Pharm Inc | Aminopyridinyl-,aminoguanidinyl-, and alkoxyguanidinesubstituted phenylsubstituted phenylacetamides as protease inhibitors |
US7015223B1 (en) | 2000-11-20 | 2006-03-21 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl 1,2,4-triazinones useful for selective inhibition of the coagulation cascade |
EP1351686A2 (en) | 2000-11-20 | 2003-10-15 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade |
US7119094B1 (en) | 2000-11-20 | 2006-10-10 | Warner-Lambert Company | Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade |
US20030236257A1 (en) * | 2001-04-04 | 2003-12-25 | South Michael S. | Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the cogulation cascade |
DE10133786A1 (de) * | 2001-07-16 | 2003-02-06 | Boehringer Ingelheim Pharma | Verwendung von Thrombin-Inhibitoren zur Behandlung von Arthritis |
WO2003093242A2 (en) * | 2001-10-03 | 2003-11-13 | Pharmacia Corporation | Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade |
US20040082585A1 (en) * | 2001-10-03 | 2004-04-29 | Pharmacia Corporation | Prodrugs of substituted polycyclic compounds useful for selective inhibition of the coagulation cascade |
CA2462647A1 (en) * | 2001-10-03 | 2003-04-10 | Michael S. South | 6-membered unsaturated heterocyclic compounds useful for selective inhibition of the coagulation cascade |
MXPA04003163A (es) * | 2001-10-03 | 2004-07-08 | Pharmacia Corp | Compuestos heterociclicos de 6 elementos utiles para inhibicion selectiva de la casdada de coagulacion. |
WO2003048127A1 (en) | 2001-12-04 | 2003-06-12 | Corvas International, Inc. | Aromatic heterocyclic non-covalent inhibitors of urokinase and blood vessel formation |
WO2004050637A2 (en) | 2002-12-03 | 2004-06-17 | Axys Pharmaceuticals, Inc. | 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors |
DE602004021365D1 (de) * | 2003-04-10 | 2009-07-16 | Ortho Mcneil Pharm Inc | Substituierte phenylacetamide und ihre anwendung als protease inhibitoren |
US7087622B2 (en) | 2004-05-07 | 2006-08-08 | Janssen Pharmaceutica N.V. | Pyridone compounds as inhibitors of bacterial type III protein secreation systems |
US20050281798A1 (en) * | 2004-06-16 | 2005-12-22 | Glen Gong | Targeting sites of damaged lung tissue using composition |
US7608579B2 (en) * | 2004-06-16 | 2009-10-27 | Pneumrx, Inc. | Lung volume reduction using glue compositions |
US20050281739A1 (en) * | 2004-06-16 | 2005-12-22 | Glen Gong | Imaging damaged lung tissue using compositions |
US20050281799A1 (en) | 2004-06-16 | 2005-12-22 | Glen Gong | Targeting damaged lung tissue using compositions |
US7678767B2 (en) | 2004-06-16 | 2010-03-16 | Pneumrx, Inc. | Glue compositions for lung volume reduction |
US20050281740A1 (en) * | 2004-06-16 | 2005-12-22 | Glen Gong | Imaging damaged lung tissue |
US7553810B2 (en) * | 2004-06-16 | 2009-06-30 | Pneumrx, Inc. | Lung volume reduction using glue composition |
US7766938B2 (en) | 2004-07-08 | 2010-08-03 | Pneumrx, Inc. | Pleural effusion treatment device, method and material |
WO2007127392A2 (en) * | 2006-04-27 | 2007-11-08 | Pronovost Allan D | Devices and methods for collecting oral samples of enriched serous fluid |
US7758001B2 (en) * | 2006-09-13 | 2010-07-20 | Premier Mounts | Mount with magnetic attachment and automatic safety latching |
WO2008036763A2 (en) * | 2006-09-20 | 2008-03-27 | Pneumrx, Inc. | Tissue adhesive compositions and methods thereof |
WO2008137779A2 (en) | 2007-05-03 | 2008-11-13 | Intermune, Inc. | Novel macrocyclic inhibitors of hepatitis c virus replication |
EP2164325B1 (en) | 2007-05-31 | 2013-04-24 | Shionogi&Co., Ltd. | Oxyimino compounds and the use thereof |
WO2009151152A1 (en) | 2008-06-11 | 2009-12-17 | Shionogi & Co., Ltd. | Oxycarbamoyl compounds and the use thereof |
EP3018481B1 (en) * | 2009-05-20 | 2018-02-21 | Sekisui Medical Co., Ltd. | Blood coagulation time prolonging agent |
US8349832B2 (en) * | 2009-09-02 | 2013-01-08 | Canthera Therapeutics | Compounds and compositions for treating cancer |
US8318737B2 (en) | 2009-09-02 | 2012-11-27 | Canthera Therapeutics Inc. | Compounds and compositions for treating cancer |
NO2655399T3 (US06566379-20030520-C00022.png) | 2010-12-21 | 2018-02-24 | ||
WO2012091757A1 (en) * | 2010-12-31 | 2012-07-05 | Corridor Pharmaceuticals, Inc. | Arginase inhibitors and methods of use thereof |
US9788539B2 (en) | 2011-05-17 | 2017-10-17 | Velico Medical, Inc. | Platelet protection solution having beta-galactosidase and sialidase inhibitors |
WO2012158983A2 (en) | 2011-05-17 | 2012-11-22 | Qiyong Peter Liu | Improved platelet storage using a sialidase inhibitor |
WO2014055988A1 (en) | 2012-10-05 | 2014-04-10 | Velico Medical, Inc. | Platelet additive solution having a beta-galactosidase inhibitor |
WO2014120886A1 (en) | 2013-01-30 | 2014-08-07 | Velico Medical, Inc. | Platelet additive solution having a self-assembling hydrogel-forming peptide |
US20150365084A1 (en) * | 2014-06-13 | 2015-12-17 | Infineon Technologies Austria Ag | Circuits and methods for operating a circuit |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4097472A (en) | 1974-11-08 | 1978-06-27 | Mitsubishi Chemical Industries Limited | N2 -arylsulfonyl-l-argininamides and the pharmaceutically acceptable salts thereof |
SU328634A1 (ru) | 1971-01-05 | 1978-01-05 | Butyrin V G | Устройство дл забора проб крови у животных |
SU938739A3 (ru) | 1977-01-19 | 1982-06-23 | Мицубиси Кемикал Индастриз Лимитед(Фирма) | Способ получени N -арилсульфонил-L-аргининамидов или их солей |
US4418052A (en) * | 1980-08-12 | 1983-11-29 | Wong Dennis W | Diagnostic compositions and method for radiologic imaging of fibrinogen deposition in the body |
US4980148A (en) * | 1985-02-06 | 1990-12-25 | Mallinckrodt, Inc. | Methods for enhancing magnetic resonance imaging |
US5011686A (en) * | 1987-09-21 | 1991-04-30 | Creative Biomolecules, Inc. | Thrombus specific conjugates |
ZA897514B (en) * | 1988-10-07 | 1990-06-27 | Merrell Dow Pharma | Novel peptidase inhibitors |
US5024829A (en) * | 1988-11-21 | 1991-06-18 | Centocor, Inc. | Method of imaging coronary thrombi |
US5656600A (en) * | 1993-03-25 | 1997-08-12 | Corvas International, Inc. | α-ketoamide derivatives as inhibitors of thrombosis |
US5658885A (en) * | 1993-04-27 | 1997-08-19 | The Dupont Merck Pharmaceutical Company | Amidino and guanidino substituted boronic acid inhibitors of trypsin-like enzymes |
GB9318637D0 (en) | 1993-09-08 | 1993-10-27 | Ferring Res Ltd | Enzyme inhibitors |
US5466811A (en) * | 1994-07-18 | 1995-11-14 | Merck & Co., Inc. | Dioxolenylmethyl carbamates pro moieties for amine drugs |
US5656645A (en) * | 1994-12-13 | 1997-08-12 | Corvas International, Inc. | Aromatic heterocyclic derivatives as enzyme inhibitors |
NZ298699A (en) * | 1994-12-13 | 2001-03-30 | Corvas Int Inc | 3-amino-1,2-dihydropyrid-1-yl(and 5-amino-1,6-dihydro-6-oxo(and 5,6-dioxo)pyrimidin-1-yl)-acetyl-argininal derivatives, useful for the treatment of blood coagulation and thrombosis |
US5658930A (en) * | 1994-12-13 | 1997-08-19 | Corvas International, Inc. | Aromatic heterocyclic derivatives as enzyme inhibitors |
WO1997001338A1 (en) * | 1995-06-27 | 1997-01-16 | Merck & Co., Inc. | Pyridinone-thrombin inhibitors |
AU720616B2 (en) * | 1996-02-22 | 2000-06-08 | Merck & Co., Inc. | Pyridinone thrombin inhibitors |
CA2250426C (en) | 1996-03-29 | 2006-05-02 | 3-Dimensional Pharmaceuticals, Inc. | Amidinohydrazones as protease inhibitors |
TW499412B (en) | 1996-11-26 | 2002-08-21 | Dimensional Pharm Inc | Aminoguanidines and alkoxyguanidines as protease inhibitors |
PL340560A1 (en) * | 1997-11-26 | 2001-02-12 | Dimensional Pharmaceuticals 3 | Heteroaryl aminoguanidines and alkoxyguanidines and their application as protease inhibitors |
DE69926884T2 (de) * | 1998-06-11 | 2006-06-14 | Johnson & Johnson Pharm Res | Pyrazine protease inhibitore |
WO2000073302A1 (en) | 1999-05-27 | 2000-12-07 | 3-Dimensional Pharmaceuticals, Inc. | Oxazaheterocycles as protease inhibitors |
WO2001004117A1 (en) | 1999-07-09 | 2001-01-18 | 3-Dimensional Pharmaceuticals, Inc. | Heteroaryl protease inhibitors and diagnostic imaging agents |
US6236492B1 (en) * | 1999-08-03 | 2001-05-22 | Crystal Corporation | Electrode with a balanced centroid, soft edges and an apodization ratio greater than one |
-
1998
- 1998-11-25 PL PL98340560A patent/PL340560A1/xx not_active Application Discontinuation
- 1998-11-25 WO PCT/US1998/025185 patent/WO1999026926A1/en active IP Right Grant
- 1998-11-25 JP JP2000522084A patent/JP2001524467A/ja active Pending
- 1998-11-25 DE DE69836346T patent/DE69836346T2/de not_active Expired - Fee Related
- 1998-11-25 CA CA002311969A patent/CA2311969A1/en not_active Abandoned
- 1998-11-25 US US09/199,167 patent/US6037356A/en not_active Expired - Lifetime
- 1998-11-25 BR BR9815325-0A patent/BR9815325A/pt not_active Application Discontinuation
- 1998-11-25 AU AU17991/99A patent/AU751412B2/en not_active Ceased
- 1998-11-25 ES ES98962838T patent/ES2274587T3/es not_active Expired - Lifetime
- 1998-11-25 AT AT98962838T patent/ATE344246T1/de not_active IP Right Cessation
- 1998-11-25 TW TW087119488A patent/TWI222441B/zh not_active IP Right Cessation
- 1998-11-25 EP EP98962838A patent/EP1036063B1/en not_active Expired - Lifetime
- 1998-11-25 EA EA200000578A patent/EA004180B1/ru not_active IP Right Cessation
- 1998-11-26 AR ARP980106006A patent/AR016702A1/es unknown
-
2000
- 2000-01-14 US US09/482,540 patent/US6245763B1/en not_active Expired - Lifetime
-
2001
- 2001-04-06 US US09/827,292 patent/US6350764B2/en not_active Expired - Lifetime
- 2001-12-12 US US10/012,445 patent/US6472399B2/en not_active Expired - Lifetime
-
2002
- 2002-09-12 US US10/241,513 patent/US6566379B1/en not_active Expired - Lifetime
-
2003
- 2003-03-27 US US10/400,073 patent/US6706021B2/en not_active Expired - Lifetime
- 2003-11-17 US US10/714,988 patent/US7029654B2/en not_active Expired - Lifetime
-
2005
- 2005-10-19 US US11/254,086 patent/US7402586B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EA200000578A1 (ru) | 2001-02-26 |
US6566379B1 (en) | 2003-05-20 |
AR016702A1 (es) | 2001-07-25 |
US20060211719A1 (en) | 2006-09-21 |
JP2001524467A (ja) | 2001-12-04 |
US20040106633A1 (en) | 2004-06-03 |
US20030225115A1 (en) | 2003-12-04 |
US7029654B2 (en) | 2006-04-18 |
US6245763B1 (en) | 2001-06-12 |
AU1799199A (en) | 1999-06-15 |
WO1999026926A1 (en) | 1999-06-03 |
CA2311969A1 (en) | 1999-06-03 |
AU751412B2 (en) | 2002-08-15 |
DE69836346D1 (de) | 2006-12-14 |
US20020007070A1 (en) | 2002-01-17 |
DE69836346T2 (de) | 2007-05-24 |
US20020086872A1 (en) | 2002-07-04 |
PL340560A1 (en) | 2001-02-12 |
EA004180B1 (ru) | 2004-02-26 |
US7402586B2 (en) | 2008-07-22 |
EP1036063A1 (en) | 2000-09-20 |
TWI222441B (en) | 2004-10-21 |
US6350764B2 (en) | 2002-02-26 |
US6472399B2 (en) | 2002-10-29 |
US6037356A (en) | 2000-03-14 |
ES2274587T3 (es) | 2007-05-16 |
US20030087921A1 (en) | 2003-05-08 |
US6706021B2 (en) | 2004-03-16 |
EP1036063B1 (en) | 2006-11-02 |
ATE344246T1 (de) | 2006-11-15 |
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