BR9811992A - Derivados de ciclopeptìdeos - Google Patents
Derivados de ciclopeptìdeosInfo
- Publication number
- BR9811992A BR9811992A BR9811992-3A BR9811992A BR9811992A BR 9811992 A BR9811992 A BR 9811992A BR 9811992 A BR9811992 A BR 9811992A BR 9811992 A BR9811992 A BR 9811992A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- cyclopeptide derivatives
- cyclopeptide
- derivatives
- integrin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Patente de Invenção: <B>"DERIVADOS DE CICLOPEPTìDEOS"<D>. Composto de fórmula I em que X, A, B e C têm os significados indicados na reivindicação 1, e seus sais, podem ser usados como inibidores da integrina, em particular na profilaxia e tratamento de doenças da circulação, tromboses, enfarte do coração, doenças coronarianas, aterosclerose, em processos patológicos suportados ou propagados pela angiogênese e no tratamento de tumores.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19736772A DE19736772A1 (de) | 1997-08-23 | 1997-08-23 | Cyclopeptidderivate |
PCT/EP1998/005161 WO1999010371A2 (de) | 1997-08-23 | 1998-08-14 | Cyclopeptidderivate als adhäsionsinhibitoren |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9811992A true BR9811992A (pt) | 2000-09-05 |
Family
ID=7839977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9811992-3A BR9811992A (pt) | 1997-08-23 | 1998-08-14 | Derivados de ciclopeptìdeos |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1007545A2 (pt) |
JP (1) | JP2001514186A (pt) |
KR (1) | KR20010022828A (pt) |
CN (1) | CN1267306A (pt) |
AR (1) | AR013650A1 (pt) |
AU (1) | AU734829B2 (pt) |
BR (1) | BR9811992A (pt) |
CA (1) | CA2301182A1 (pt) |
DE (1) | DE19736772A1 (pt) |
HU (1) | HUP0003500A3 (pt) |
ID (1) | ID23952A (pt) |
NO (1) | NO20000860D0 (pt) |
PL (1) | PL341090A1 (pt) |
RU (1) | RU2200166C2 (pt) |
SK (1) | SK2132000A3 (pt) |
TW (1) | TW477793B (pt) |
WO (1) | WO1999010371A2 (pt) |
ZA (1) | ZA987558B (pt) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA43823C2 (uk) * | 1992-07-06 | 2002-01-15 | Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг | ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ІНГІБУВАННЯ ІНТЕГРИН <font face="Symbol">a</font><sub>V</sub><font face="Symbol">b</font><sub>3</sub>-ОПОСЕРЕДКОВАНОЇ КЛІТИННОЇ АДГЕЗІЇ КЛІТИН ССАВЦІВ, СПОСІБ ЛІКУВАННЯ ТА ПРОФІЛАКТИКИ ЗАХВОРЮВАННЯ, АСОЦІЙОВАНОГО З ПОРУШЕННЯМ АДГЕЗІЇ КЛІТИН, СПОСІБ БЛОКУВАННЯ ЗВ'ЯЗУВАННЯ ФІБРИНОГЕНОМ ІНТЕГРИНУ, КОМПОЗИЦІЯ ДЛЯ ЗАГОЄННЯ РАН |
DE4310643A1 (de) * | 1993-04-01 | 1994-10-06 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
DE4415310A1 (de) * | 1994-04-30 | 1995-11-02 | Merck Patent Gmbh | Cyclopeptide |
JPH07316193A (ja) * | 1994-05-24 | 1995-12-05 | Asahi Glass Co Ltd | ペプチド誘導体およびその用途 |
-
1997
- 1997-08-23 DE DE19736772A patent/DE19736772A1/de not_active Withdrawn
-
1998
- 1998-08-14 HU HU0003500A patent/HUP0003500A3/hu unknown
- 1998-08-14 BR BR9811992-3A patent/BR9811992A/pt not_active IP Right Cessation
- 1998-08-14 PL PL98341090A patent/PL341090A1/xx unknown
- 1998-08-14 WO PCT/EP1998/005161 patent/WO1999010371A2/de not_active Application Discontinuation
- 1998-08-14 KR KR1020007001430A patent/KR20010022828A/ko not_active Application Discontinuation
- 1998-08-14 AU AU95319/98A patent/AU734829B2/en not_active Ceased
- 1998-08-14 EP EP98948833A patent/EP1007545A2/de not_active Withdrawn
- 1998-08-14 RU RU2000107122/04A patent/RU2200166C2/ru not_active IP Right Cessation
- 1998-08-14 CA CA002301182A patent/CA2301182A1/en not_active Abandoned
- 1998-08-14 ID IDW20000532A patent/ID23952A/id unknown
- 1998-08-14 SK SK213-2000A patent/SK2132000A3/sk unknown
- 1998-08-14 CN CN98808380A patent/CN1267306A/zh active Pending
- 1998-08-14 JP JP2000507697A patent/JP2001514186A/ja active Pending
- 1998-08-19 TW TW087113657A patent/TW477793B/zh not_active IP Right Cessation
- 1998-08-20 ZA ZA987558A patent/ZA987558B/xx unknown
- 1998-08-21 AR ARP980104136A patent/AR013650A1/es not_active Application Discontinuation
-
2000
- 2000-02-22 NO NO20000860A patent/NO20000860D0/no unknown
Also Published As
Publication number | Publication date |
---|---|
SK2132000A3 (en) | 2000-09-12 |
PL341090A1 (en) | 2001-03-26 |
NO20000860L (no) | 2000-02-22 |
AU734829B2 (en) | 2001-06-21 |
WO1999010371A2 (de) | 1999-03-04 |
NO20000860D0 (no) | 2000-02-22 |
KR20010022828A (ko) | 2001-03-26 |
CA2301182A1 (en) | 1999-03-04 |
EP1007545A2 (de) | 2000-06-14 |
HUP0003500A3 (en) | 2001-12-28 |
TW477793B (en) | 2002-03-01 |
AU9531998A (en) | 1999-03-16 |
HUP0003500A2 (hu) | 2001-02-28 |
JP2001514186A (ja) | 2001-09-11 |
WO1999010371A3 (de) | 1999-05-27 |
ZA987558B (en) | 1999-02-23 |
RU2200166C2 (ru) | 2003-03-10 |
DE19736772A1 (de) | 1999-02-25 |
ID23952A (id) | 2000-06-08 |
AR013650A1 (es) | 2001-01-10 |
CN1267306A (zh) | 2000-09-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6O, 7O, 8O E 9O ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007. |