BR9811981A - Sistemas de expressão para liberar uma proteìna e um anticorpo recombinante em um ovo, processos para imunizar um animal, para preparação de uma proteìna e de um anticorpo recombinante em um ovo, para preparação de um ovo que é isento de um patógeno, ovo, linhagem de célula de aves transformada, e, animal ovìparo transgênico - Google Patents

Sistemas de expressão para liberar uma proteìna e um anticorpo recombinante em um ovo, processos para imunizar um animal, para preparação de uma proteìna e de um anticorpo recombinante em um ovo, para preparação de um ovo que é isento de um patógeno, ovo, linhagem de célula de aves transformada, e, animal ovìparo transgênico

Info

Publication number
BR9811981A
BR9811981A BR9811981-8A BR9811981A BR9811981A BR 9811981 A BR9811981 A BR 9811981A BR 9811981 A BR9811981 A BR 9811981A BR 9811981 A BR9811981 A BR 9811981A
Authority
BR
Brazil
Prior art keywords
egg
preparing
protein
recombinant antibody
animal
Prior art date
Application number
BR9811981-8A
Other languages
English (en)
Inventor
Robert J Etches
Manssor Mohammed
Sherie Morrison
Letitia Alice Wims
Kham M Trinh
Alan G Wildeman
Original Assignee
Univ Guelph
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Guelph, Univ California filed Critical Univ Guelph
Publication of BR9811981A publication Critical patent/BR9811981A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/02—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from eggs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/30—Bird
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

''SISTEMAS DE EXPRESSãO PARA LIBERAR UMA PROTEìNA E UM ANTICORPO RECOMBINANTE EM UM OVO, PROCESSOS PARA IMUNIZAR UM ANIMAL, PARA PREPARAçãO DE UMA PROTEìNA E DE UM ANTICORPO RECOMBINANTE EM UM OVO, PARA PREPARAçãO DE UM OVO QUE é ISENTO DE UM PATóGENO, OVO, LINHAGEM DE CéLULA DE AVES TRANSFORMADA, E, ANIMAL OVìPARO TRANSGêNICO''. Processos para preparar proteínas recombinantes, como anticorpos, em ovos são descritos. O processo oferece vantagens sobre os sistemas existentes para preparar proteínas recombinantes incluindo alto rendimento, baixo custo e compatibilidade com as leis de proteção de animais. Além disso, porque os ovos são fontes de alimentos comestíveis, a proteína recombinante não precisa ser isolada do ovo.
BR9811981-8A 1997-08-22 1998-08-21 Sistemas de expressão para liberar uma proteìna e um anticorpo recombinante em um ovo, processos para imunizar um animal, para preparação de uma proteìna e de um anticorpo recombinante em um ovo, para preparação de um ovo que é isento de um patógeno, ovo, linhagem de célula de aves transformada, e, animal ovìparo transgênico BR9811981A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5686597P 1997-08-22 1997-08-22
PCT/CA1998/000792 WO1999010505A2 (en) 1997-08-22 1998-08-21 Production of proteins in eggs

Publications (1)

Publication Number Publication Date
BR9811981A true BR9811981A (pt) 2000-08-15

Family

ID=22007036

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9811981-8A BR9811981A (pt) 1997-08-22 1998-08-21 Sistemas de expressão para liberar uma proteìna e um anticorpo recombinante em um ovo, processos para imunizar um animal, para preparação de uma proteìna e de um anticorpo recombinante em um ovo, para preparação de um ovo que é isento de um patógeno, ovo, linhagem de célula de aves transformada, e, animal ovìparo transgênico

Country Status (12)

Country Link
EP (1) EP1007697B1 (pt)
JP (2) JP4731683B2 (pt)
KR (1) KR20010023179A (pt)
AT (1) ATE356878T1 (pt)
AU (1) AU750028B2 (pt)
BR (1) BR9811981A (pt)
CA (1) CA2311116A1 (pt)
DE (1) DE69837337T2 (pt)
HK (1) HK1028623A1 (pt)
IL (2) IL134618A0 (pt)
NZ (1) NZ503098A (pt)
WO (1) WO1999010505A2 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2375441A1 (en) * 1999-06-04 2000-12-14 Tranxenogen, Inc. Methods for manipulating the avian genome
FR2796385A1 (fr) * 1999-07-16 2001-01-19 Inst Nat Sante Rech Med Methode de production d'anticorps dans le jaune d'oeuf et utilisation des anticorps ainsi obtenus
IL154751A0 (en) * 2000-08-03 2003-10-31 Humanized antibodies, recombination vectors, transgenic vectors and methods for the preparation of humanized antibodies from transgenic animals
US7049480B1 (en) * 2000-09-01 2006-05-23 Avigenics, Inc. Methods of enucleating an avian oocyte or zygote using two-photon laser scanning microscopy
US20020108132A1 (en) * 2001-02-02 2002-08-08 Avigenics Inc. Production of a monoclonal antibody by a transgenic chicken
US7339090B2 (en) 2001-02-13 2008-03-04 Avigenics, Inc. Microinjection devices and methods of use
GB0119497D0 (en) * 2001-08-10 2001-10-03 Viragen Inc Expression of modified antibodies in avian cells
ATE513038T1 (de) 2001-09-18 2011-07-15 Synageva Biopharma Corp Produktion eines transgenen vogels mittels cytoplasmainjektion
US7550650B2 (en) 2001-09-18 2009-06-23 Synageva Biopharma Corp. Production of a transgenic avian by cytoplasmic injection
KR100471117B1 (ko) * 2001-12-12 2005-03-08 주식회사 단바이오텍 로타바이러스 감염의 예방 및 치료에 유용한 수용성단백질 및 이를 포함한 알 및 이들의 제조방법
US7145057B2 (en) * 2002-02-01 2006-12-05 Origen Therapeutics, Inc. Chimeric bird from embryonic stem cells
EP1480675A4 (en) * 2002-02-08 2005-10-26 Tranxenogen Inc IMMUNOGLOBULIN PURIFICATION
KR20040018589A (ko) * 2002-08-23 2004-03-04 주식회사 한국야쿠르트 로타바이러스 항체 및 이를 함유하는 면역난황/면역란,그리고 이들의 생산 방법
US20080222744A1 (en) 2003-05-09 2008-09-11 Avigenics, Inc. In vivo transfection in avians
US7381712B2 (en) 2003-05-09 2008-06-03 Avigenics, Inc. In vivo transfection in avians
US20050090001A1 (en) 2003-10-07 2005-04-28 Parker Stephen H. Cell lines and methods for producing proteins
EP1790716A1 (en) 2005-11-23 2007-05-30 UMC Utrecht Holding B.V. Uses of the FcRn receptor
JP2009082033A (ja) * 2007-09-28 2009-04-23 Kaneka Corp 完全ヒト型抗体生産法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1306946C (en) * 1985-11-25 1992-09-01 Hideo Tokoro Specific antibody-containing substance from eggs and method of production and use thereof
JPH0753669B2 (ja) * 1985-11-25 1995-06-07 株式会社ゲン・コーポレーション 鶏卵からの特異的抗体含有材料およびその製造方法と用途
PT92900A (pt) * 1989-01-24 1990-07-31 Sistema de vectores de expressao para a producao de anticorpos monoclonais quimericos
EP0394827A1 (en) * 1989-04-26 1990-10-31 F. Hoffmann-La Roche Ag Chimaeric CD4-immunoglobulin polypeptides
GB9223377D0 (en) * 1992-11-04 1992-12-23 Medarex Inc Humanized antibodies to fc receptors for immunoglobulin on human mononuclear phagocytes
JPH08507687A (ja) * 1993-03-12 1996-08-20 クレイトン ユニバーシティ 遺伝子治療用の改良されたベクター
JPH07138297A (ja) * 1993-11-12 1995-05-30 Sumitomo Electric Ind Ltd キメラ分子
KR970010968A (ko) * 1995-08-24 1997-03-27 윤원영 오리 배 세포를 이용한 에리스로포이틴의 발현 시스템
DE19607367A1 (de) * 1996-02-27 1997-08-28 Progen Biotechnik Gmbh Herstellung von transgenem Geflügel durch Gentransfer mit p95-spezifischen Genfähren
JPH09275849A (ja) * 1996-04-17 1997-10-28 Eisai Co Ltd 卵管粘膜に外来遺伝子を導入した産卵鶏
US6825396B2 (en) * 1996-06-12 2004-11-30 Board Of Trustees Operating Michigan State University Methods for tissue specific synthesis of protein in eggs of transgenic hens

Also Published As

Publication number Publication date
ATE356878T1 (de) 2007-04-15
IL134618A0 (en) 2001-04-30
HK1028623A1 (en) 2001-02-23
KR20010023179A (ko) 2001-03-26
JP2011050393A (ja) 2011-03-17
DE69837337D1 (de) 2007-04-26
IL134618A (en) 2011-07-31
JP4731683B2 (ja) 2011-07-27
WO1999010505A2 (en) 1999-03-04
EP1007697B1 (en) 2007-03-14
WO1999010505A3 (en) 1999-05-20
DE69837337T2 (de) 2008-02-21
EP1007697A2 (en) 2000-06-14
JP2001514005A (ja) 2001-09-11
AU8848598A (en) 1999-03-16
AU750028B2 (en) 2002-07-11
NZ503098A (en) 2002-06-28
CA2311116A1 (en) 1999-03-04

Similar Documents

Publication Publication Date Title
BR9811981A (pt) Sistemas de expressão para liberar uma proteìna e um anticorpo recombinante em um ovo, processos para imunizar um animal, para preparação de uma proteìna e de um anticorpo recombinante em um ovo, para preparação de um ovo que é isento de um patógeno, ovo, linhagem de célula de aves transformada, e, animal ovìparo transgênico
Morishige et al. Immunostimulatory effects of collagen from jellyfish in vivo
Bandman Continued expression of neonatal myosin heavy chain in adult dystrophic skeletal muscle
Takemura Changes in an immunoglobulin M (IgM)-like protein during larval stages in tilapia, Oreochromis mossambicus
Takemura et al. Transfer of maternally-derived immunoglobulin (IgM) to larvae in tilapia, Oreochromis mossambicus
HK1087949A1 (en) Immunogene adherence and method of making and using the same
Scanes et al. Reproductive management of poultry
KR19990022555A (ko) 인히빈 조성물 및 증식 성능 개선 방법
Kaspers et al. Transfer of IgA from albumen into the yolk sac during embryonic development in the chicken
BR9704313A (pt) Utilização de ig-y de ovo de galinha associado a anticorpos monoclonais contra antigenos sexo especifico na imunosexagem de espermatozóides de bovinos
Burke Sex differences in weight of turkey embryos
Blaese et al. Infectious agammaglobulinemia: Suppressor T cells with specificity for individual immunoglobulin classes
Erickson et al. Effects of mate familiarity on the courtship and reproductive success of the ring dove (Streptopelia risoria)
Kuwayama et al. Effects of removal of chicks from hens on concentrations of prolactin, luteinizing hormone and oestradiol in plasma of brooding Gifujidori hens
Neurath et al. Solubilization and some properties of the erythrocyte receptor for adenovirus type 7 haemagglutinin
Boogaard et al. The effects of estradiol and progesterone on the growth and differentiation of the quail oviduct
Counihan et al. Immune parameters in different age classes of captive male Steller's eiders (Polysticta stelleri)
Vieira-Pires et al. Other Avian Species: Ostrich, Quail, Turkey, Duck and Goose
Lassila et al. Migration of prebursal stem cells from the early chicken embryo to the yolk sac
Spies et al. The effects of body weight and long ahemeral days on early production parameters and morphological characteristics of broiler breeder hens
Verdier et al. Partial characterization of antigenic sperm proteins in foxes (Vulpes vulpes)
Huriaux et al. Expression of myofibrillar proteins and parvalbumin isoforms in white muscle of dorada during development
CN110590928B (zh) 一种PiT-1单克隆抗体、制备方法及应用
Tsuji et al. Some characteristics of hepatic ornithine transcarbamylase from the house musk shrew, Suncus murinus
KANKI et al. Bursal Role in the Synthesis of γ-Chain Messenger Ribonucleic Acid in Young Chickens

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6O, 7O, 8O E 9O ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007.