BR9811657A - Clonagem usando-se núcleos doadores oriundos de células diferenciadas não-carentes de soro - Google Patents

Clonagem usando-se núcleos doadores oriundos de células diferenciadas não-carentes de soro

Info

Publication number
BR9811657A
BR9811657A BR9811657-6A BR9811657A BR9811657A BR 9811657 A BR9811657 A BR 9811657A BR 9811657 A BR9811657 A BR 9811657A BR 9811657 A BR9811657 A BR 9811657A
Authority
BR
Brazil
Prior art keywords
cells
differentiated
serum
production
cloning
Prior art date
Application number
BR9811657-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Steven L Stice
Jose Cibelli
James M Robl
Paul Golueke
F Abel Ponce De Leon
D Joseph Jerry
Original Assignee
Univ Massachusetts Public Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Massachusetts Public Inst filed Critical Univ Massachusetts Public Inst
Publication of BR9811657A publication Critical patent/BR9811657A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8771—Bovine embryos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/02—Cells from transgenic animals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/04—Cells produced using nuclear transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Psychology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
BR9811657-6A 1997-07-03 1998-06-24 Clonagem usando-se núcleos doadores oriundos de células diferenciadas não-carentes de soro BR9811657A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88828397A 1997-07-03 1997-07-03
PCT/US1998/012800 WO1999001163A1 (en) 1997-07-03 1998-06-24 Cloning using donor nuclei from non-serum starved, differentiated cells

Publications (1)

Publication Number Publication Date
BR9811657A true BR9811657A (pt) 2000-09-05

Family

ID=25392916

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9811657-6A BR9811657A (pt) 1997-07-03 1998-06-24 Clonagem usando-se núcleos doadores oriundos de células diferenciadas não-carentes de soro

Country Status (9)

Country Link
EP (1) EP1017422A4 (de)
JP (1) JP2001509361A (de)
CN (2) CN101003800A (de)
AU (1) AU8154398A (de)
BR (1) BR9811657A (de)
CA (1) CA2294916A1 (de)
IL (1) IL133786A0 (de)
NZ (1) NZ502129A (de)
WO (1) WO1999001163A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235969B1 (en) * 1997-01-10 2001-05-22 University Of Massachusetts Cloning pigs using donor nuclei from non-quiescent differentiated cells
DE59812083D1 (de) * 1998-01-16 2004-11-11 Agrobiogen Gmbh Effizienter kerntransfer mit fetalen fibroblasten
US6331659B1 (en) 1998-01-21 2001-12-18 University Of Hawaii Cumulus cells as nuclear donors
WO1999046982A1 (en) * 1998-03-16 1999-09-23 Relag Pty Ltd Porcine nuclear transfer
AUPP294898A0 (en) * 1998-04-15 1998-05-07 Monash University Method of nuclear transfer
US6781030B1 (en) 1998-11-02 2004-08-24 Trustee Of Tufts College, Ballou Hall Methods for cloning mammals using telophase oocytes
EP1375654A3 (de) * 1998-11-02 2008-01-16 GTC Biotherapeutics, Inc. Transgen- und klonierte Saugentiere
EP1818397A1 (de) * 1998-11-02 2007-08-15 Trustees Of Tufts College Verfahren zur Klonierung von Tieren
WO2000025578A2 (en) * 1999-04-26 2000-05-11 Trustees Of Tufts College Methods for cloning animals
ES2338631T3 (es) 1999-03-04 2010-05-11 Revivicor, Inc. Modificacion genetica de celulas somaticas y usos de las mismas.
AU753209B2 (en) * 1999-06-30 2002-10-10 Seoul National University Industry Foundation Method for producing cloned tigers by employing inter-species nuclear transplantation technique
RU2205536C2 (ru) * 1999-06-30 2003-06-10 Воо-Сук ХВАНГ Способ получения клонированной коровы
RU2216591C2 (ru) * 1999-06-30 2003-11-20 Воо-Сук ХВАНГ Способ получения клонированных эмбрионов человека путем применения способа межвидовой трансплантации ядер
EP1226239A4 (de) * 1999-10-15 2003-02-12 Advanced Cell Tech Inc Verfahren zur Herstellung von differenzierten Vorläuferzellen und embryonalen Stammzellen mit Liniendefekten
DE10084883D2 (de) * 2000-06-08 2004-04-29 Trostner Jens Verfahren zur genetischen Rekonstruktion von menschlichen Organen
AU8470301A (en) 2000-08-03 2002-02-18 Wim-Van Schooten Production of humanized antibodies in transgenic animals
FR2814642B1 (fr) 2000-10-03 2005-07-01 Ass Pour Le Dev De La Rech En Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee
US20020168763A1 (en) * 2000-11-30 2002-11-14 Yan Wen Liang Isolated homozygous stem cells, differentiated cells derived therefrom, and materials and methods for making and using same
ATE466089T1 (de) 2000-12-22 2010-05-15 Agronomique Inst Nat Rech Positionsunabhängige und gewebespezifische expression eines transgens in der milch eines transgen-tieres
JP4420604B2 (ja) * 2000-12-22 2010-02-24 協和発酵キリン株式会社 再プログラムしたドナークロマチンまたはドナー細胞を用いて哺乳類をクローニングする方法
EP1425386A4 (de) 2001-08-13 2007-05-02 Embrex Inc Verfahren zur injektion von vogeleiern
CN1650003A (zh) * 2002-04-01 2005-08-03 Gtc生物治疗学公司 选择用于哺乳动物种中核转移的细胞系的方法
US7612250B2 (en) 2002-07-29 2009-11-03 Trustees Of Tufts College Nuclear transfer embryo formation method
CN102719444B (zh) 2006-09-01 2016-12-14 人类多细胞株治疗学公司 人或人源化免疫球蛋白在非人转基因动物中增强的表达
EP2267153A1 (de) 2009-05-26 2010-12-29 Université Claude Bernard Lyon 1 Identifizierung der Netrin-1-Rezeptor-unc5c-Genmutation bei festen Krebsen
WO2013010045A1 (en) 2011-07-12 2013-01-17 Biotime Inc. Novel methods and formulations for orthopedic cell therapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0739412B1 (de) * 1993-12-23 2002-02-27 Infigen, Inc. EMBRYONALE STAMMZELLEN von Huftieren ALS KERNDONATOREN UND KERNTRANSFERTECHNIKEN ZUR HERSTELLUNG CHIMÄRER UND TRANSGENER TIERE
GB9517779D0 (en) 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
GB9517780D0 (en) * 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
US5945577A (en) 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
DE59812083D1 (de) * 1998-01-16 2004-11-11 Agrobiogen Gmbh Effizienter kerntransfer mit fetalen fibroblasten

Also Published As

Publication number Publication date
CN1265599A (zh) 2000-09-06
NZ502129A (en) 2005-02-25
WO1999001163A1 (en) 1999-01-14
IL133786A0 (en) 2001-04-30
EP1017422A1 (de) 2000-07-12
AU8154398A (en) 1999-01-25
JP2001509361A (ja) 2001-07-24
EP1017422A4 (de) 2002-10-29
CA2294916A1 (en) 1999-01-14
CN101003800A (zh) 2007-07-25

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. PORTANTO, INDEFIRO O PRESENTE PEDIDO DE PATENTE COMO INVENCAO - DE ACORDO COM O ART. 8O DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.