WO2000026357A3 - Transgenic and cloned mammals - Google Patents
Transgenic and cloned mammals Download PDFInfo
- Publication number
- WO2000026357A3 WO2000026357A3 PCT/US1999/025710 US9925710W WO0026357A3 WO 2000026357 A3 WO2000026357 A3 WO 2000026357A3 US 9925710 W US9925710 W US 9925710W WO 0026357 A3 WO0026357 A3 WO 0026357A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- transgenic
- cloned
- methods
- somatic cell
- mammals
- Prior art date
Links
- 230000009261 transgenic effect Effects 0.000 title abstract 5
- 241000124008 Mammalia Species 0.000 title abstract 4
- 210000001082 somatic cell Anatomy 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 2
- 210000001161 mammalian embryo Anatomy 0.000 abstract 2
- 210000000287 oocyte Anatomy 0.000 abstract 2
- 241000283707 Capra Species 0.000 abstract 1
- 210000002257 embryonic structure Anatomy 0.000 abstract 1
- 230000016853 telophase Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
- C12N15/8772—Caprine embryos
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0273—Cloned vertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/102—Caprine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Developmental Biology & Embryology (AREA)
- Microbiology (AREA)
- Environmental Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU14622/00A AU1462200A (en) | 1998-11-02 | 1999-11-02 | Transgenic and cloned mammals |
JP2000579729A JP4523165B2 (en) | 1998-11-02 | 1999-11-02 | Transgenic and cloned mammals |
CA002350233A CA2350233A1 (en) | 1998-11-02 | 1999-11-02 | Transgenic and cloned mammals |
EP99971451A EP1127113A2 (en) | 1998-11-02 | 1999-11-02 | Transgenic and cloned mammals |
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10672898P | 1998-11-02 | 1998-11-02 | |
US60/106,728 | 1998-11-02 | ||
US29850899A | 1999-04-22 | 1999-04-22 | |
US09/298,508 | 1999-04-22 | ||
US09/298,971 US6580017B1 (en) | 1998-11-02 | 1999-04-23 | Methods of reconstructed goat embryo transfer |
US09/298,971 | 1999-04-23 | ||
US13132899P | 1999-04-26 | 1999-04-26 | |
US60/131,328 | 1999-04-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000026357A2 WO2000026357A2 (en) | 2000-05-11 |
WO2000026357A3 true WO2000026357A3 (en) | 2000-11-23 |
Family
ID=27493534
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/025710 WO2000026357A2 (en) | 1998-11-02 | 1999-11-02 | Transgenic and cloned mammals |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1127113A2 (en) |
JP (2) | JP4523165B2 (en) |
AU (1) | AU1462200A (en) |
CA (1) | CA2350233A1 (en) |
WO (1) | WO2000026357A2 (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6781030B1 (en) | 1998-11-02 | 2004-08-24 | Trustee Of Tufts College, Ballou Hall | Methods for cloning mammals using telophase oocytes |
JP2004518405A (en) * | 2000-07-27 | 2004-06-24 | アポゲーネ・ゲーエムベーハー・ウント・コー・カーゲー | Somatic cell cloning gene transfer to produce recombinant proteins, cells, and organisms |
CN1558949A (en) * | 2001-11-06 | 2004-12-29 | �Ϻ��ڶ�ҽ�ƴ�ѧ | Preparing somatic embryo by utilizing rabbit oocyte |
US7612250B2 (en) | 2002-07-29 | 2009-11-03 | Trustees Of Tufts College | Nuclear transfer embryo formation method |
CA2501415A1 (en) * | 2002-08-01 | 2004-02-12 | Gtc Biotherapeutics, Inc. | Method of selecting cells for somatic cell nuclear transfer |
WO2011060489A1 (en) * | 2009-11-18 | 2011-05-26 | Murray Goulburn Co-Operative Co. Limited | Transgenic non-human animals |
CN104082239B (en) * | 2014-06-10 | 2016-01-20 | 张海员 | A kind of method for culturing special microbial strain for original ecological live pigs |
FR3025515B1 (en) | 2014-09-05 | 2016-09-09 | Lab Francais Du Fractionnement | PROCESS FOR PURIFYING MONOCLONAL ANTIBODY |
US11246299B2 (en) | 2015-03-04 | 2022-02-15 | Pormedtec Co., Ltd. | Disease model pig exhibiting stable phenotype, and production method thereof |
FR3034420A1 (en) | 2015-03-31 | 2016-10-07 | Lab Francais Du Fractionnement | ANTI-CD303 MONOCLONAL ANTIBODIES |
US10961556B2 (en) | 2016-08-15 | 2021-03-30 | Danmarks Tekniske Universitet | Method for reducing ammonium and lactate production in CHO cells |
FR3060395B1 (en) | 2016-12-16 | 2019-05-24 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | COMBINATION OF ANTI-CD303 AND ANTI-HER2 ANTIBODIES |
FR3060394B1 (en) | 2016-12-16 | 2019-05-24 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | COMBINATION OF ANTI-CD303 AND ANTI-AMHRII ANTIBODIES |
FR3076294B1 (en) | 2017-12-29 | 2022-01-28 | Lab Francais Du Fractionnement | METHOD FOR PURIFYING ANTIBODIES FROM RAW MILK |
CN109315355A (en) * | 2018-11-21 | 2019-02-12 | 江西和乐园生态农业科技发展有限公司 | A kind of goat cultural method |
AU2022422400A1 (en) | 2021-12-20 | 2024-07-11 | Vetoquinol Sa | Anti-canine interleukine-31-receptor a (il-31ra) antibodies and the uses thereof |
WO2024165823A2 (en) | 2023-02-09 | 2024-08-15 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Mutant fab fragment for obtaining site-specific mono-or bifunctionalised conjugates |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996026268A1 (en) * | 1995-02-21 | 1996-08-29 | Genzyme Transgenics Corporation | Transgenically produced antithrombin iii |
WO1997007669A1 (en) * | 1995-08-31 | 1997-03-06 | Roslin Institute (Edinburgh) | Quiescent cell populations for nuclear transfer |
WO1997019589A1 (en) * | 1995-11-30 | 1997-06-05 | Nexia Biotechnologies, Inc. | Method for development of transgenic goats |
-
1999
- 1999-11-02 AU AU14622/00A patent/AU1462200A/en not_active Abandoned
- 1999-11-02 EP EP99971451A patent/EP1127113A2/en not_active Withdrawn
- 1999-11-02 WO PCT/US1999/025710 patent/WO2000026357A2/en active Application Filing
- 1999-11-02 CA CA002350233A patent/CA2350233A1/en not_active Abandoned
- 1999-11-02 JP JP2000579729A patent/JP4523165B2/en not_active Expired - Fee Related
-
2003
- 2003-06-26 JP JP2003182181A patent/JP4068516B2/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996026268A1 (en) * | 1995-02-21 | 1996-08-29 | Genzyme Transgenics Corporation | Transgenically produced antithrombin iii |
WO1997007669A1 (en) * | 1995-08-31 | 1997-03-06 | Roslin Institute (Edinburgh) | Quiescent cell populations for nuclear transfer |
WO1997019589A1 (en) * | 1995-11-30 | 1997-06-05 | Nexia Biotechnologies, Inc. | Method for development of transgenic goats |
Non-Patent Citations (7)
Title |
---|
BAGUISI A, ET AL.: "Production of goats by somatic cell nuclear transfer.", NAT BIOTECHNOL, vol. 17, no. 5, May 1999 (1999-05-01), pages 456 - 461, XP000891364 * |
BORDIGNON,V. & SMITH L.C.: "TELOPHASE ENUCLEATION: AN IMPROVED METHOD TO PREPARE RECIPIENT CYTOPLASTS FOR USE IN BOVINE NUCLEAR TRANSFER", MOLECULAR REPRODUCTION AND DEVELOPMENT, vol. 49, no. 1, January 1998 (1998-01-01), US,NEW YORK, pages 29 - 36, XP000910821 * |
EBERT K M ET AL: "TRANSGENIC FARM ANIMALS: PROGRESS REPORT", THERIOGENOLOGY,US,LOS ALTOS, CA, vol. 39, no. 1, 1 January 1993 (1993-01-01), pages 121 - 135, XP000565804, ISSN: 0093-691X * |
GOOTWINE, E. ET AL.: "Factors affecting success of embryo collection and transfer in a transgenic goat program.", THERIOGENOLOGY, (1997) VOL. 48, NO. 3, PP. 485-499., XP000892953 * |
LEWIS-WILLIAMS J., ET AL.: "BIRTH OF SUCCESSFULLY IDENTIFIED TRANSGENIC GOATS USING PREIMPLANTATION STAGE EMBRYOS BIOPSIED FOR FISH.", THERIOGENOLOGY, LOS ALTOS, CA, US, vol. 47., no. 01., 1 January 1997 (1997-01-01), US, pages 226., XP000892951, ISSN: 0093-691X, DOI: 10.1016/S0093-691X(97)82353-9 * |
LEWIS-WILLIAMS, J. ET AL.: "Birth of successfully identified transgenic goats using preimplantation stage embryos biopsied for fish.", THERIOGENOLOGY, (1997) VOL. 47, NO. 1, PP. 226. * |
WILMUT I ET AL: "VIABLE OFFSPRING DERIVED FROM FETAL AND ADULT MAMMALIAN CELLS", NATURE,GB,MACMILLAN JOURNALS LTD. LONDON, vol. 385, no. 6619, 27 February 1997 (1997-02-27), pages 810 - 813, XP002067035, ISSN: 0028-0836 * |
Also Published As
Publication number | Publication date |
---|---|
WO2000026357A2 (en) | 2000-05-11 |
JP2002528117A (en) | 2002-09-03 |
JP4068516B2 (en) | 2008-03-26 |
AU1462200A (en) | 2000-05-22 |
JP2004073189A (en) | 2004-03-11 |
EP1127113A2 (en) | 2001-08-29 |
CA2350233A1 (en) | 2000-05-11 |
JP4523165B2 (en) | 2010-08-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2000026357A3 (en) | Transgenic and cloned mammals | |
WO2001050848A3 (en) | Clonal propagation of primate offspring by embryo splitting | |
IL126416A0 (en) | Cultured inner cell mass cell lines derived from ungulate embryos | |
EP1017423A4 (en) | Cloning pigs using donor nuclei from differentiated cells | |
NZ336612A (en) | Cloning using donor nuclei from proliferating somatic cells | |
NO20001105L (en) | Transgenic mammals that form oligosaccharides in the milk | |
WO2004016742A3 (en) | α(1,3)-GALACTOSYLTRANSFERASE NULL CELLS, METHODS OF SELECTING AND α(1,3)-GALACTOSYLTRANSFERASE NULL SWINE PRODUCED THEREFROM | |
WO2009021151A8 (en) | Isolation, characterization and propagation of germline stem cells | |
ATE281516T1 (en) | METHOD FOR PRODUCING MAMMALS WITH DEFINED GENETIC CHARACTERISTICS | |
EP1019491A4 (en) | Production of avian embryonic germ (eg) cell lines by prolonged culturing of pgcs, use thereof for cloning and chimerization | |
WO2002010337A3 (en) | Method of cloning porcine animals | |
FR2812004B1 (en) | CULTURE MEDIA FOR IN VITRO FERTILIZATION, OR FOR THE CULTURE OF FOLLICLES, MALE GERMINAL CELLS OR EMBRYOS | |
AU4861999A (en) | Use of the first polar body chromosomes for the production of embryos | |
EP1375654A3 (en) | Transgenic and cloned mammals | |
EP1711599A4 (en) | Embryonic stem cell line and method for preparing the same | |
EP1395111A4 (en) | Cloning of transgenic animals comprising artificial chromosomes | |
DE60017931D1 (en) | IMPROVED METHOD FOR THE PRODUCTION OF CLONED PIG EMBRYOS BY SOMATIC CELL CORE TRANSFER | |
CA2431859A1 (en) | Transgenic and cloned mammals | |
WO2002020752A3 (en) | Cloned cells, embryos, and avians and methods, of producing them | |
WO2006036975A3 (en) | Methods of embryo transfer | |
WO2001032008A8 (en) | Methods for sexing non-human mammals | |
WO2003054170A8 (en) | Compositions for the in vitro derivation and culture of embryonic stem (es) cell lines with germline transmission capability and for the culture of adult stem cells | |
AU2406099A (en) | Renegeration of somatic embryos from plant tissues | |
WO2000069257A3 (en) | Genetic modification of male germ cells for generation of transgenic species and genetic therapies | |
WO2002023983A3 (en) | Method of producing non-human mammals |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ENP | Entry into the national phase |
Ref country code: AU Ref document number: 2000 14622 Kind code of ref document: A Format of ref document f/p: F |
|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US US US US UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
AK | Designated states |
Kind code of ref document: A3 Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US US US US UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
ENP | Entry into the national phase |
Ref document number: 2350233 Country of ref document: CA Ref country code: CA Ref document number: 2350233 Kind code of ref document: A Format of ref document f/p: F |
|
ENP | Entry into the national phase |
Ref country code: JP Ref document number: 2000 579729 Kind code of ref document: A Format of ref document f/p: F |
|
WWE | Wipo information: entry into national phase |
Ref document number: 14622/00 Country of ref document: AU |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1999971451 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 1999971451 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |