BR0013959A - Clonagem de porcos usando células ou núcleos doadores a partir de células diferenciadas e produção de porcino pluripotente - Google Patents
Clonagem de porcos usando células ou núcleos doadores a partir de células diferenciadas e produção de porcino pluripotenteInfo
- Publication number
- BR0013959A BR0013959A BR0013959-9A BR0013959A BR0013959A BR 0013959 A BR0013959 A BR 0013959A BR 0013959 A BR0013959 A BR 0013959A BR 0013959 A BR0013959 A BR 0013959A
- Authority
- BR
- Brazil
- Prior art keywords
- production
- cells
- donor
- differentiated
- nuclei
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Abstract
Patente de Invenção: "CLONAGEM DE PORCOS USANDO CéLULAS OU NúCLEOS DOADORES A PARTIR DE CéLULAS DIFERENCIADAS E PRODUçãO DE PORCINO PLURIPOTENTE". é proporcionado um método aperfeiçoado de transferência nuclear envolvendo a transplantação de núcleos de células de porcos diferenciadas doadores em oócitos de porcas enucleados. As unidades de transferência nuclear resultantes são úteis para a multiplicação de genótipos e de genótipos transgênicos pela produção de fetos e proles. A produção de embriões, fetos e proles de porcos geneticamente engenheirados ou transgênicos é facilitada pelo presente método, visto que a fonte de células diferenciadas dos núcleos doadores pode ser geneticamente modificada e propagada de forma cional.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/394,902 US7291764B1 (en) | 1997-01-10 | 1999-09-13 | Cloning pigs using non-quiescent differentiated donor cells or nuclei |
PCT/US2000/024958 WO2001019181A1 (en) | 1999-09-13 | 2000-09-13 | Cloning pigs using donor cells or nuclei from differentiated cells and production of pluripotent porcine. |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0013959A true BR0013959A (pt) | 2002-05-21 |
Family
ID=23560867
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0013959-9A BR0013959A (pt) | 1999-09-13 | 2000-09-13 | Clonagem de porcos usando células ou núcleos doadores a partir de células diferenciadas e produção de porcino pluripotente |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1241931A4 (pt) |
JP (1) | JP2003509031A (pt) |
CN (1) | CN1377225A (pt) |
AU (1) | AU7372500A (pt) |
BR (1) | BR0013959A (pt) |
CA (1) | CA2381124A1 (pt) |
IL (1) | IL148508A0 (pt) |
MX (1) | MXPA02002653A (pt) |
WO (1) | WO2001019181A1 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004275074A (ja) * | 2003-03-14 | 2004-10-07 | Nipro Corp | 動物胚における正常性のスクリーニング方法 |
CN100404675C (zh) * | 2006-02-22 | 2008-07-23 | 李宁 | 一种生产体细胞克隆猪的方法 |
WO2008106984A2 (en) * | 2007-03-07 | 2008-09-12 | Aarhus Universitet | Pig model for breast cancer, mitochondria related protein folding disorders and/or epidermolysis bullosa simplex |
AU2015360502A1 (en) | 2014-12-10 | 2017-06-29 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
JP6929527B2 (ja) | 2015-03-04 | 2021-09-01 | 株式会社ポル・メド・テック | 安定した表現型を示す疾患モデルブタおよびその作製方法 |
KR20190017985A (ko) * | 2016-06-14 | 2019-02-20 | 리전츠 오브 더 유니버스티 오브 미네소타 | 질환을 치료하기 위한 유전적으로 변형된 세포, 조직, 및 장기 |
CN111349615A (zh) * | 2018-12-24 | 2020-06-30 | 上海细胞治疗集团有限公司 | 制备过表达外源基因的细胞的方法 |
CN115305260B (zh) * | 2021-11-30 | 2023-09-22 | 海南大学 | 一种金鲳鱼受精卵的显微注射方法及应用 |
CN116640804A (zh) * | 2023-04-20 | 2023-08-25 | 云南农业大学 | 一种基于体细胞核移植技术构建三倍体猪的方法 |
CN117044679B (zh) * | 2023-10-13 | 2024-01-19 | 成都铁骑力士饲料有限公司 | 一种血清fas在川藏黑猪s05系瘦肉型猪选育中的应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE213771T1 (de) * | 1993-12-23 | 2002-03-15 | Infigen Inc | Embryonale stammzellen von huftieren als kerndonatoren und kerntransfertechniken zur herstellung chimärer und transgener tiere |
US5905042A (en) * | 1996-04-01 | 1999-05-18 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Cultured inner cell mass cell lines derived from bovine or porcine embryos |
US5945577A (en) * | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
US6235969B1 (en) * | 1997-01-10 | 2001-05-22 | University Of Massachusetts | Cloning pigs using donor nuclei from non-quiescent differentiated cells |
-
2000
- 2000-09-13 CN CN00813714A patent/CN1377225A/zh active Pending
- 2000-09-13 CA CA002381124A patent/CA2381124A1/en not_active Abandoned
- 2000-09-13 AU AU73725/00A patent/AU7372500A/en not_active Abandoned
- 2000-09-13 BR BR0013959-9A patent/BR0013959A/pt not_active Application Discontinuation
- 2000-09-13 MX MXPA02002653A patent/MXPA02002653A/es not_active Application Discontinuation
- 2000-09-13 WO PCT/US2000/024958 patent/WO2001019181A1/en active Application Filing
- 2000-09-13 JP JP2001522835A patent/JP2003509031A/ja active Pending
- 2000-09-13 EP EP00961827A patent/EP1241931A4/en not_active Withdrawn
- 2000-09-13 IL IL14850800A patent/IL148508A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
MXPA02002653A (es) | 2003-10-14 |
JP2003509031A (ja) | 2003-03-11 |
WO2001019181A1 (en) | 2001-03-22 |
AU7372500A (en) | 2001-04-17 |
EP1241931A1 (en) | 2002-09-25 |
CA2381124A1 (en) | 2000-09-13 |
CN1377225A (zh) | 2002-10-30 |
EP1241931A4 (en) | 2004-12-29 |
IL148508A0 (en) | 2002-09-12 |
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Legal Events
Date | Code | Title | Description |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A ANUIDADE. |
|
B08H | Application fees: decision cancelled [chapter 8.8 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1849 DE 13/06/2006 POR TER SIDO APRESENTADA PAPELETA DE ESCLARECIMENTO. |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |