BR0209028A - Método de transferência nuclear - Google Patents
Método de transferência nuclearInfo
- Publication number
- BR0209028A BR0209028A BR0209028-7A BR0209028A BR0209028A BR 0209028 A BR0209028 A BR 0209028A BR 0209028 A BR0209028 A BR 0209028A BR 0209028 A BR0209028 A BR 0209028A
- Authority
- BR
- Brazil
- Prior art keywords
- nuclear transfer
- transfer method
- relates
- present
- somatic cell
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 210000001082 somatic cell Anatomy 0.000 abstract 2
- 210000002257 embryonic structure Anatomy 0.000 abstract 1
- 210000004940 nucleus Anatomy 0.000 abstract 1
- 210000000287 oocyte Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Developmental Biology & Embryology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"MéTODO DE TRANSFERêNCIA NUCLEAR". A presente invenção se refere a métodos de transferência nuclear e embriões desenvolvidos a partir dos mesmos. Em particular, a presente invenção se refere a métodos de transferência nuclear compreendendo a etapa de transferir uma célula somática ou núcleos de célula somática em um oócito enucleado livre de zona pellucida.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPR4514A AUPR451401A0 (en) | 2001-04-20 | 2001-04-20 | A method of nuclear transfer |
| PCT/AU2002/000491 WO2002086103A1 (en) | 2001-04-20 | 2002-04-19 | A method of nuclear transfer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0209028A true BR0209028A (pt) | 2005-05-31 |
Family
ID=3828509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0209028-7A BR0209028A (pt) | 2001-04-20 | 2002-04-19 | Método de transferência nuclear |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20040177390A1 (pt) |
| JP (1) | JP2004529648A (pt) |
| CN (1) | CN1524121A (pt) |
| AU (1) | AUPR451401A0 (pt) |
| BR (1) | BR0209028A (pt) |
| CA (1) | CA2444621A1 (pt) |
| NZ (1) | NZ529007A (pt) |
| WO (1) | WO2002086103A1 (pt) |
Families Citing this family (58)
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| US7807862B2 (en) * | 2003-09-30 | 2010-10-05 | Sterrenbeld Biotechnologie North America, Inc. | Transgenic bovine comprising human growth hormone in its serum and methods of making |
| US8513486B2 (en) | 2005-09-08 | 2013-08-20 | Aarhus Universitet | Cell nuclear transfer |
| CN101580828B (zh) * | 2009-05-06 | 2012-06-20 | 深圳华大基因科技有限公司 | 一种细胞核移植方法 |
| CN101880689B (zh) * | 2010-06-12 | 2012-12-19 | 中国科学院西北高原生物研究所 | 藏羚羊-牛种间体细胞核移植胚胎的构建与体外发育方法 |
| CN101880690B (zh) * | 2010-06-12 | 2012-12-19 | 中国科学院西北高原生物研究所 | 藏羚羊-山羊种间克隆胚胎构建与体外培养的方法 |
| CN102766655A (zh) * | 2012-06-20 | 2012-11-07 | 中国农业科学院北京畜牧兽医研究所 | 一种生产体细胞克隆牛囊胚的方法 |
| DK3456831T3 (da) | 2013-04-16 | 2021-09-06 | Regeneron Pharma | Målrettet modifikation af rottegenom |
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| KR102170502B1 (ko) | 2013-12-11 | 2020-10-28 | 리제너론 파마슈티칼스 인코포레이티드 | 게놈의 표적화된 변형을 위한 방법 및 조성물 |
| HRP20200529T1 (hr) | 2014-06-06 | 2020-09-04 | Regeneron Pharmaceuticals, Inc. | Postupci i pripravci za modificiranje ciljnog lokusa |
| SI3161128T1 (sl) | 2014-06-26 | 2019-02-28 | Regeneron Pharmaceuticals, Inc. | Postopki in sestavki za ciljano genetsko spremembo in postopki uporabe |
| KR102531016B1 (ko) | 2014-11-21 | 2023-05-10 | 리제너론 파마슈티칼스 인코포레이티드 | 쌍 형성된 가이드 rna를 사용하는 표적화된 유전자 변형을 위한 방법 및 조성물 |
| ES2947714T3 (es) | 2014-12-19 | 2023-08-17 | Regeneron Pharma | Métodos y composiciones para la modificación genética dirigida a través de múltiples direccionamientos en un solo paso |
| AU2016233250C1 (en) | 2015-03-16 | 2022-08-18 | Regeneron Pharmaceuticals, Inc. | Non-human animal exhibiting diminished upper and lower motor neuron function and sensory perception |
| AU2016270587B2 (en) | 2015-05-29 | 2020-12-24 | Regeneron Pharmaceuticals, Inc. | Non-human animals having a disruption in a C9ORF72 locus |
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| CN108135155A (zh) | 2015-10-13 | 2018-06-08 | 佛泰尔塞夫股份有限公司 | 制备用于低温程序的生物样品的装置及方法 |
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| JP2019523009A (ja) | 2016-07-29 | 2019-08-22 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | C末端切断型フィブリリン−1の発現をもたらす変異を有するマウス |
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| EP3585161A1 (en) | 2017-07-31 | 2020-01-01 | Regeneron Pharmaceuticals, Inc. | Assessment of crispr/cas-induced recombination with an exogenous donor nucleic acid in vivo |
| US20190098879A1 (en) | 2017-09-29 | 2019-04-04 | Regeneron Pharmaceuticals, Inc. | Non-Human Animals Comprising A Humanized TTR Locus And Methods Of Use |
| JP7097440B2 (ja) | 2017-11-10 | 2022-07-07 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Slc30a8変異を含む非ヒト動物および使用方法 |
| JP7361031B2 (ja) | 2017-11-30 | 2023-10-13 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | ヒト化trkb遺伝子座を含む非ヒト動物 |
| EP3592140A1 (en) | 2018-03-19 | 2020-01-15 | Regeneron Pharmaceuticals, Inc. | Transcription modulation in animals using crispr/cas systems |
| JP7222075B2 (ja) | 2018-09-13 | 2023-02-14 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | C3糸球体症のモデルとしての補体因子h遺伝子ノックアウトラット |
| KR102925054B1 (ko) | 2018-12-20 | 2026-02-10 | 리제너론 파마슈티칼스 인코포레이티드 | 뉴클레아제-매개 반복부 팽창 |
| KR102661779B1 (ko) | 2019-04-04 | 2024-04-30 | 리제너론 파마슈티칼스 인코포레이티드 | 인간화 응고 인자 12 좌위를 포함하는 비-인간 동물 |
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| EP3990475A1 (en) | 2019-06-27 | 2022-05-04 | Regeneron Pharmaceuticals, Inc. | Modeling tdp-43 proteinopathy |
| CN110904034A (zh) * | 2019-11-15 | 2020-03-24 | 芜湖职业技术学院 | 一种去除卵细胞细胞核的方法 |
| WO2021108363A1 (en) | 2019-11-25 | 2021-06-03 | Regeneron Pharmaceuticals, Inc. | Crispr/cas-mediated upregulation of humanized ttr allele |
| CN111004775B (zh) * | 2020-01-08 | 2023-05-02 | 中国医学科学院医学生物学研究所 | 一种物理性去除卵母细胞透明带的方法 |
| WO2021154791A1 (en) | 2020-01-28 | 2021-08-05 | Regeneron Pharmaceuticals, Inc. | Non-human animals comprising a humanized pnpla3 locus and methods of use |
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| US20230102342A1 (en) | 2020-03-23 | 2023-03-30 | Regeneron Pharmaceuticals, Inc. | Non-human animals comprising a humanized ttr locus comprising a v30m mutation and methods of use |
| WO2021263146A2 (en) | 2020-06-26 | 2021-12-30 | Regeneron Pharmaceuticals, Inc. | Non-human animals comprising a humanized ace2 locus |
| CN113061572A (zh) * | 2021-04-21 | 2021-07-02 | 广西壮族自治区畜牧研究所 | 手工克隆程序中无透明带胚胎培养的微穴改进方法 |
| IL312505A (en) | 2021-11-04 | 2024-07-01 | Regeneron Pharma | Non-human animals comprising a modified cacng1 locus |
| KR20240117571A (ko) | 2021-12-08 | 2024-08-01 | 리제너론 파마슈티칼스 인코포레이티드 | 돌연변이 마이오실린 질환 모델 및 이의 용도 |
| US20250049006A1 (en) | 2021-12-20 | 2025-02-13 | C/O Regeneron Pharmaceuticals, Inc. | Non-human animals comprising humanized ace2 and tmprss loci |
| CN114350600B (zh) * | 2022-01-26 | 2023-08-18 | 中国农业大学 | 一种提高冷冻卵母细胞体外培育质量的培养液及其应用 |
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Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ336493A (en) * | 1997-01-02 | 2001-01-26 | Univ Monash | A method of oocyte enucleation and production of reconstituted embryos |
-
2001
- 2001-04-20 AU AUPR4514A patent/AUPR451401A0/en not_active Abandoned
-
2002
- 2002-04-19 WO PCT/AU2002/000491 patent/WO2002086103A1/en not_active Ceased
- 2002-04-19 CN CNA028125819A patent/CN1524121A/zh active Pending
- 2002-04-19 BR BR0209028-7A patent/BR0209028A/pt not_active IP Right Cessation
- 2002-04-19 US US10/475,168 patent/US20040177390A1/en not_active Abandoned
- 2002-04-19 JP JP2002583618A patent/JP2004529648A/ja active Pending
- 2002-04-19 NZ NZ529007A patent/NZ529007A/en unknown
- 2002-04-19 CA CA002444621A patent/CA2444621A1/en not_active Abandoned
-
2007
- 2007-06-08 US US11/808,383 patent/US20080092249A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2444621A1 (en) | 2002-10-31 |
| NZ529007A (en) | 2005-05-27 |
| JP2004529648A (ja) | 2004-09-30 |
| AUPR451401A0 (en) | 2001-05-24 |
| US20080092249A1 (en) | 2008-04-17 |
| US20040177390A1 (en) | 2004-09-09 |
| CN1524121A (zh) | 2004-08-25 |
| WO2002086103A1 (en) | 2002-10-31 |
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Legal Events
| Date | Code | Title | Description |
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| B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
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| B08E | Application fees: payment of additional fee required [chapter 8.5 patent gazette] |
Free format text: COMPLEMENTAR 7A ANUIDADE DE ACORDO COM TABELA VIGENTE REFERENTE A GUIA 220805229806 E COMPROVAR RECOLHIMENTO DA 8A ANUIDADE. |
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| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2099 DE 29/03/2011. |
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| B15K | Others concerning applications: alteration of classification |
Ipc: C12N 15/873 (2010.01) |