BR9809677A - Nitrometil cetonas, processo para o preparo das mesmas e composições contendo as mesmas - Google Patents
Nitrometil cetonas, processo para o preparo das mesmas e composições contendo as mesmasInfo
- Publication number
- BR9809677A BR9809677A BR9809677-0A BR9809677A BR9809677A BR 9809677 A BR9809677 A BR 9809677A BR 9809677 A BR9809677 A BR 9809677A BR 9809677 A BR9809677 A BR 9809677A
- Authority
- BR
- Brazil
- Prior art keywords
- compositions containing
- preparing
- ketones
- same
- nitromethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
- C07C233/33—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/61—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/76—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/56—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/60—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Patente de Invenção: <B>"NITROMETIL CETONAS, PROCESSO PARA O PREPARO DAS MESMAS E COMPOSIçõES CONTENDO AS MESMAS"<D>. Os compostos da fórmula (I) no qual A representa C~ 6~-C~ 10~ arila ou um heterociclo de três a dez elementos opcionalmente aromático; X representa halogênio, ciano, C~ 1~-C~ 7~ alquila, trifluorometila, C~ 2~-C~ 7~ alcóxi ou trifluorometóxi; p é escolhido de 0, 1, 2, 3, 4 e 5; Z representa uma ligação, -CO-NH-, -SO~ 2~-NH-C~ 2~-C~ 7~ alquileno, enxofre, sulfinila ou sulfonila; n representa 0 ou 1; R~ 1~, R~ 2~, R~ 3~, E são conforme definidos na reivindicação 1, são inibidores da reductase de aldose.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97108369 | 1997-05-23 | ||
PCT/EP1998/002353 WO1998052906A1 (en) | 1997-05-23 | 1998-04-21 | New nitromethyl ketones, process for preparing them and compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9809677A true BR9809677A (pt) | 2000-07-11 |
Family
ID=8226821
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9809677-0A BR9809677A (pt) | 1997-05-23 | 1998-04-21 | Nitrometil cetonas, processo para o preparo das mesmas e composições contendo as mesmas |
Country Status (20)
Country | Link |
---|---|
US (4) | US5932765A (pt) |
EP (1) | EP0983226A1 (pt) |
JP (1) | JP2001526668A (pt) |
KR (1) | KR20010012712A (pt) |
CN (1) | CN1257474A (pt) |
AR (1) | AR011476A1 (pt) |
AU (1) | AU729996B2 (pt) |
BR (1) | BR9809677A (pt) |
CA (1) | CA2290831A1 (pt) |
HU (1) | HUP0001797A3 (pt) |
ID (1) | ID23157A (pt) |
MY (1) | MY133098A (pt) |
NO (1) | NO314661B1 (pt) |
PL (1) | PL336806A1 (pt) |
RU (1) | RU2194046C2 (pt) |
SG (1) | SG97828A1 (pt) |
SK (1) | SK153799A3 (pt) |
TW (1) | TW487690B (pt) |
WO (1) | WO1998052906A1 (pt) |
ZA (1) | ZA984329B (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5932765A (en) * | 1997-05-23 | 1999-08-03 | Merck Patent Gesellschaft Mit | Nitromethyl ketones, process for preparing them and compositions containing them |
US20060281768A1 (en) * | 2005-06-10 | 2006-12-14 | Gaul Michael D | Thienopyrimidine and thienopyridine kinase modulators |
MX2009011615A (es) * | 2007-06-05 | 2009-11-10 | Sanofi Aventis | Acidos benzoilamino-indan-2-carboxilicos sustituidos y compuestos relacionados. |
CN110357809B (zh) * | 2018-04-10 | 2020-10-02 | 新发药业有限公司 | 一种4-甲基哌啶-3-酮及其衍生物的简便制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1456992A (en) * | 1973-04-03 | 1976-12-01 | Beecham Group Ltd | 2-2-nitroacetyl-benzoic acid derivatives |
US4117137A (en) * | 1976-09-20 | 1978-09-26 | Sandoz, Inc. | 2-amino-pyridyl nitromethylketones and 2-amino-phenyl nitromethylketones |
US4381304A (en) * | 1981-08-21 | 1983-04-26 | Ayerst, Mckenna & Harrison, Inc. | 4,9-Dihydro-4,9-dioxo-1H-cyclohepta[b]pyridine derivatives |
US4382088A (en) * | 1981-08-21 | 1983-05-03 | Ayerst, Mckenna & Harrison, Inc. | 4,7-Dihydro-4,7-dioxi-1H-cyclohepta[b]pyridine derivatives |
GB8718619D0 (en) * | 1987-08-06 | 1987-09-09 | Ici Plc | Pharmaceutical compositions |
IE63463B1 (en) * | 1989-02-06 | 1995-04-19 | Zeneca Ltd | Phenylsulphone derivatives |
US5360822A (en) * | 1990-02-07 | 1994-11-01 | Nippon Shinyaku Co. Ltd. | Sulfonanilide derivatives and medicine |
WO1993025545A1 (en) * | 1992-06-09 | 1993-12-23 | Korea Research Institute Of Chemical Technology | Novel quinoline derivatives and processes for preparing the same |
US5932765A (en) * | 1997-05-23 | 1999-08-03 | Merck Patent Gesellschaft Mit | Nitromethyl ketones, process for preparing them and compositions containing them |
-
1997
- 1997-10-22 US US08/955,624 patent/US5932765A/en not_active Expired - Fee Related
-
1998
- 1998-04-21 CA CA002290831A patent/CA2290831A1/en not_active Abandoned
- 1998-04-21 WO PCT/EP1998/002353 patent/WO1998052906A1/en not_active Application Discontinuation
- 1998-04-21 RU RU99126651/04A patent/RU2194046C2/ru not_active IP Right Cessation
- 1998-04-21 ID IDW991275A patent/ID23157A/id unknown
- 1998-04-21 SK SK1537-99A patent/SK153799A3/sk unknown
- 1998-04-21 JP JP54985598A patent/JP2001526668A/ja active Pending
- 1998-04-21 AU AU75280/98A patent/AU729996B2/en not_active Ceased
- 1998-04-21 BR BR9809677-0A patent/BR9809677A/pt not_active IP Right Cessation
- 1998-04-21 KR KR1019997010673A patent/KR20010012712A/ko not_active Application Discontinuation
- 1998-04-21 EP EP98922757A patent/EP0983226A1/en not_active Withdrawn
- 1998-04-21 SG SG200000025A patent/SG97828A1/en unknown
- 1998-04-21 CN CN98805323A patent/CN1257474A/zh active Pending
- 1998-04-21 PL PL98336806A patent/PL336806A1/xx unknown
- 1998-04-21 HU HU0001797A patent/HUP0001797A3/hu unknown
- 1998-05-08 TW TW087107161A patent/TW487690B/zh active
- 1998-05-20 MY MYPI98002230A patent/MY133098A/en unknown
- 1998-05-21 ZA ZA984329A patent/ZA984329B/xx unknown
- 1998-05-22 AR ARP980102395A patent/AR011476A1/es not_active Application Discontinuation
-
1999
- 1999-02-25 US US09/257,046 patent/US6043281A/en not_active Expired - Fee Related
- 1999-11-12 US US09/438,979 patent/US6559185B2/en not_active Expired - Fee Related
- 1999-11-22 NO NO19995724A patent/NO314661B1/no not_active IP Right Cessation
-
2003
- 2003-02-12 US US10/364,372 patent/US20030171422A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR20010012712A (ko) | 2001-02-26 |
ID23157A (id) | 2000-03-23 |
CA2290831A1 (en) | 1998-11-26 |
HUP0001797A3 (en) | 2002-01-28 |
WO1998052906A1 (en) | 1998-11-26 |
JP2001526668A (ja) | 2001-12-18 |
US6559185B2 (en) | 2003-05-06 |
MY133098A (en) | 2007-10-31 |
AR011476A1 (es) | 2000-08-16 |
HUP0001797A2 (hu) | 2000-10-28 |
NO314661B1 (no) | 2003-04-28 |
US6043281A (en) | 2000-03-28 |
AU729996B2 (en) | 2001-02-22 |
CN1257474A (zh) | 2000-06-21 |
US5932765A (en) | 1999-08-03 |
SK153799A3 (en) | 2000-05-16 |
TW487690B (en) | 2002-05-21 |
SG97828A1 (en) | 2003-08-20 |
PL336806A1 (en) | 2000-07-17 |
RU2194046C2 (ru) | 2002-12-10 |
EP0983226A1 (en) | 2000-03-08 |
US20030171422A1 (en) | 2003-09-11 |
NO995724L (no) | 1999-11-22 |
NO995724D0 (no) | 1999-11-22 |
ZA984329B (en) | 1999-03-03 |
US20030069312A1 (en) | 2003-04-10 |
AU7528098A (en) | 1998-12-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9901298A (pt) | Novos compostos de benzotiofeno, benzofurano e indol, um processo para sua preparação e composições farmacêuticas que os contêm | |
DK0769010T3 (da) | 2-[1',2',4'-triazol-3'-yloxymethylen]-anilider og deres anvendelse som pesticider | |
BR0309534A (pt) | Composto, composição farmacêutica, e, uso de um composto | |
BR9910326A (pt) | Processo para preeparar isoxazóis, composto, processo para preparar compostos, uso de compostos, e, processo para preparar tioéteres | |
BR0008763A (pt) | Derivados de piridopiranoazepinas, a preparação dos mesmos e a respectiva aplicação em terapêutica | |
BRPI0411721A (pt) | derivados de tiazolilpiperidina como inibidores de mtp | |
BR0005866A (pt) | Composição de resina fotossensìvel | |
BR0013041A (pt) | Composto heterociclico e composição farmacêutica para tratar e prevenir doenças mediadas por cgmp-pde, seu uso e método | |
BR0102319A (pt) | Monoacilalquilfosfinas organometálicas | |
BR9803832A (pt) | Emulsões de compostos de organossilício para a hidrofobização de materiais de construção | |
BR9804437A (pt) | Compostos para a osteoporose | |
BRPI0113162B8 (pt) | compostos ariloxialquilaminas nao-imidazólicos e composição farmacêutica compreendendo os referidos compostos | |
BR0011282A (pt) | Derivados da purina, seu processo de preparo e composiçoes farmacêuticas que as contêm | |
BR9916328A (pt) | Inibidores de transferase de farnesila | |
CO5251438A1 (es) | Derivados del acido hidroxamico sustituidos por arilsul- fonamido, compuestos y composiciones farmaceuticas que los contienen y procedimiento para su aplicacion y preparacion | |
BR9809677A (pt) | Nitrometil cetonas, processo para o preparo das mesmas e composições contendo as mesmas | |
BR0108989A (pt) | Trifluorobutenos nematicidas | |
BR0013075A (pt) | Derivados de tetrazolinona | |
BR0013292A (pt) | Derivados de benzenamina como anti-coagulantes | |
BR0212982A (pt) | Processo para preparar um composto, e, composto | |
BR0100107A (pt) | Compostos de benzenossulfonamida, um processo para sua preparação e composições farmacêuticas que contêm os mesmos | |
BR9813756A (pt) | Derivados da acronicina, seu processo de preparo e as composições farmacêuticas que as contêm | |
MXPA03008248A (es) | Agentes colorantes para fibras de queratina que contienen derivados de n-heteroarilmetil-m-fenilendiamina, asi como nuevos derivados de n-heteroarilmetil-m-fenilendiamina. | |
BR9609991A (pt) | Carbamoilcarboxamida composição adequada para controlar fungos nocivos processos para a preparação de uma carbamoilcarboxamida para preparação da composição e para controle de fungos nocivos e uso de um composto ou de uma composição | |
BR0306707A (pt) | Derivados de 5-(piridin-3-il)-1-azabiciclo[3.2.1]octano, sua preparação e sua aplicação em terapêutica |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A,8A E 9A ANUIDADES |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007. |