BR9808676A - Molécula de ácido nucleico isolada, construção genética, processo para alterar o nìvel de ácidos graxos epóxi em uma célula, tecido, órgão ou organismo e para produzir um polipeptìdeo epoxigenase enzimaticamente ativo e um ácido graxo epoxigenado, recombinante, polipeptìdeo recombinante, planta, e, molécula de anticorpo - Google Patents

Molécula de ácido nucleico isolada, construção genética, processo para alterar o nìvel de ácidos graxos epóxi em uma célula, tecido, órgão ou organismo e para produzir um polipeptìdeo epoxigenase enzimaticamente ativo e um ácido graxo epoxigenado, recombinante, polipeptìdeo recombinante, planta, e, molécula de anticorpo

Info

Publication number
BR9808676A
BR9808676A BR9808676-6A BR9808676A BR9808676A BR 9808676 A BR9808676 A BR 9808676A BR 9808676 A BR9808676 A BR 9808676A BR 9808676 A BR9808676 A BR 9808676A
Authority
BR
Brazil
Prior art keywords
recombinant
fatty acid
fatty acids
present
plant
Prior art date
Application number
BR9808676-6A
Other languages
English (en)
Other versions
BR9808676B1 (pt
Inventor
Sten Stymne
Allan Green
Surinder Singh
Marit Lenman
Original Assignee
Commw Scient Ind Res Org
Sten Stymne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPO6226A external-priority patent/AUPO622697A0/en
Priority claimed from AUPO6223A external-priority patent/AUPO622397A0/en
Application filed by Commw Scient Ind Res Org, Sten Stymne filed Critical Commw Scient Ind Res Org
Publication of BR9808676A publication Critical patent/BR9808676A/pt
Publication of BR9808676B1 publication Critical patent/BR9808676B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Nutrition Science (AREA)
  • Environmental Sciences (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Lubricants (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"MOLéCULA DE áCIDO NUCLEICO ISOLADA, CONSTRUçãO GENéTICA, PROCESSO PARA ALTERAR O NìVEL DE áCIDOS GRAXOS EPóXI EM UMA CéLULA, TECIDO, óRGãO OU ORGANISMO E PARA PRODUZIR UM POLIPEPTìDEO EPOXIGENASE ENZIMATICAMENTE ATIVO E UM áCIDO GRAXO EPOXIGENADO, RECOMBINANTE, POLIPEPTìDEO RECOMBINANTE, PLANTA, E, MOLéCULA DE ANTICORPO". A presente invenção refere-se geralmente a novas sequências genéticas que codificam enzimas epoxigenase de ácido graxo. Em particular, a presente invenção refere-se a sequências genéticas que codificam enzimas <30>12- epoxigenase de ácido graxo, compreendendo enzimas monooxigenase de função mista. Mais preferivelmente a presente invenção provê sequências de cDNA que codificam epoxigenases de ácido graxo de plantas, particularmente a epoxigenase <30>-12 de Crepis palaestina, e homólogos, análogos e derivados dos mesmos. As sequências genéticas da presente invenção provêem os meios pelo que o metabolismo de ácido graxo pode ser alterado ou manipulado em organismos, como leveduras, mofos, bactérias, insetos, pássaros, mamíferos e plantas, particularmente para converter ácidos graxos insaturados em ácidos graxos epoxigenados nos mesmos. A invenção se estende a organismos acumulando óleo geneticamente modificados, transformados com as sequências genéticas em questão, e aos óleos derivados dos mesmos. Os óleos assim produzidos provêem os meios para as matérias primas de custo efetivo para uso na produção eficiente de revestimentos, resinas, colas, plásticos, tensoativos e lubrificantes, dentre outros.
BRPI9808676-6A 1997-04-15 1998-04-09 construção genética, processos para produzir um polipeptìdeo epoxigenase enzimaticamente ativo, recombinante, e, polipeptìdeo recombinante de ocorrência não natural. BR9808676B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AUPO6226A AUPO622697A0 (en) 1997-04-15 1997-04-15 Plant fatty acid epoxygenase genes and uses therefor IIa
AUPO6223A AUPO622397A0 (en) 1997-04-15 1997-04-15 Plant fatty acid epoxygenase genes and uses therefor Ia
US4370697P 1997-04-16 1997-04-16
US5040397P 1997-06-20 1997-06-20
PCT/AU1998/000246 WO1998046762A1 (en) 1997-04-15 1998-04-09 Plant fatty acid epoxygenase genes and uses therefor

Publications (2)

Publication Number Publication Date
BR9808676A true BR9808676A (pt) 2000-07-11
BR9808676B1 BR9808676B1 (pt) 2010-10-05

Family

ID=27424435

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9808676-6A BR9808676B1 (pt) 1997-04-15 1998-04-09 construção genética, processos para produzir um polipeptìdeo epoxigenase enzimaticamente ativo, recombinante, e, polipeptìdeo recombinante de ocorrência não natural.

Country Status (18)

Country Link
US (1) US6329518B1 (pt)
EP (1) EP0975765B1 (pt)
JP (1) JP4108765B2 (pt)
KR (1) KR100711074B1 (pt)
CN (1) CN100482797C (pt)
AT (1) ATE342361T1 (pt)
BR (1) BR9808676B1 (pt)
CA (1) CA2286895C (pt)
DE (1) DE69836133T2 (pt)
DK (1) DK0975765T3 (pt)
EA (1) EA004568B1 (pt)
ES (1) ES2275301T3 (pt)
IL (2) IL132393A0 (pt)
MX (1) MX224646B (pt)
NZ (1) NZ500542A (pt)
PL (1) PL194095B1 (pt)
TR (1) TR199902583T2 (pt)
WO (1) WO1998046762A1 (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06240940A (ja) * 1993-02-22 1994-08-30 Takigen Seizo Kk 掛金装置
US6310194B1 (en) 1994-09-26 2001-10-30 Carnegie Institution Of Washington Plant fatty acid hydroxylases
US7589253B2 (en) * 1997-04-15 2009-09-15 Commonwealth Scientific And Industrial Research Organisation Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism
BR9910125A (pt) * 1998-04-16 2003-02-25 Pierre Broun Interconversão de dessaturases e hidroxilases de ácido graxo de plantas
DE19941609A1 (de) * 1999-09-01 2001-03-08 Inst Pflanzenbiochemie Ipb Fettsäure-Desaturase-Gen aus Pflanzen
CA2408357A1 (en) * 2000-05-09 2001-11-15 Bioriginal Food & Science Corp. Production of conjugated linoleic and linolenic acids in plants
US7214520B2 (en) 2000-07-18 2007-05-08 National Research Council Of Canada Cloning, sequencing and expression of a comamonas cyclopentanone 1,2-monooxygenase-encoding gene in Escherichia coli
MXPA03000507A (es) * 2000-07-21 2003-10-06 Du Pont Enzima de citocromo p450 asociada con la sintesis de grupos delta12-epoxi en acidos grasos de plantas..
US6485949B1 (en) * 2001-01-29 2002-11-26 The United States Of America As Represented By The Secretary Of Agriculture Epoxidation of carbon-carbon double bond with membrane bound peroxygenase
EP1578987A2 (en) * 2001-08-03 2005-09-28 Diversa Corporation Epoxide hydrolases, nucleic acids encoding them and methods for making and using them
US20040157803A1 (en) * 2002-03-04 2004-08-12 Williams Deryck J. Nematicidal fatty acid and fatty acid ester related compounds
US6887900B2 (en) 2002-03-04 2005-05-03 Divergence, Inc. Nematicidal compositions and methods
US7364901B2 (en) 2002-07-15 2008-04-29 University Of Kentucky Research Foundation Recombinant Stokesia epoxygenase gene
US7365240B2 (en) 2003-02-05 2008-04-29 Divergence, Inc. Nucleic acids encoding anthelmintic agents and plants made therefrom
CN1310674C (zh) * 2003-04-30 2007-04-18 比奥滕普特公司 治疗重症急性呼吸综合征的药物组合物
WO2005014834A1 (en) * 2003-07-31 2005-02-17 The University Of York Fatty acid biosynthesis 3
WO2005014832A1 (en) * 2003-07-31 2005-02-17 The University Of York Fatty acid biosynthesis 4
AU2003255742A1 (en) * 2003-07-31 2005-02-25 The Universtiy Of York Fatty acid biosynthesis 1
US7368629B2 (en) * 2004-02-04 2008-05-06 Divergence, Inc. Nucleic acids encoding anthelmintic agents and plants made therefrom
AU2005323136A1 (en) * 2004-12-20 2006-07-13 Basf Plant Science Gmbh Nucleic acid molecules encoding fatty acid desaturase genes from plants and methods of use
ES2550623T3 (es) * 2005-05-23 2015-11-11 Blue Horse Labs, Inc. Cártamo con ácido gamma linolénico elevado
AU2009240794A1 (en) * 2008-04-25 2009-10-29 Commonwealth Scientific Industrial Research Organisation Polypeptides and methods for producing triacylglycerols comprising modified fatty acids
US8431772B1 (en) * 2008-11-19 2013-04-30 University Of Kentucky Research Foundation Diacylglycerol acyltransferase sequences and related methods
US9249082B2 (en) 2010-02-09 2016-02-02 King Abdulaziz City for Science and Technology (KACST) Synthesis of dimethyl carbonate from carbon dioxide and methanol
AU2012324024B2 (en) 2011-12-27 2016-06-16 Nuseed Global Innovation Ltd Processes for producing lipids
SG11201604871VA (en) 2013-12-18 2016-07-28 Commw Scient Ind Res Org Lipid comprising long chain polyunsaturated fatty acids
KR102527795B1 (ko) 2014-06-27 2023-05-02 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 도코사펜타에노산을 포함하는 지질
MX2017000109A (es) 2014-07-07 2017-05-23 Commw Scient Ind Res Org Procesos para producir productos industriales de lipidos vegetales.
US11913006B2 (en) 2018-03-16 2024-02-27 Nuseed Global Innovation Ltd. Plants producing modified levels of medium chain fatty acids
EP3543323A1 (de) * 2018-03-21 2019-09-25 Bergolin GmbH & Co. KG Verwendung eines insektenöls in harzen für beschichtungs- und klebstoffzusammensetzungen
CN116212948B (zh) * 2023-02-14 2024-07-09 四川九天五洋新材料有限责任公司 一种丙烯气相环氧化成型催化剂及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE115999T1 (de) 1987-12-15 1995-01-15 Gene Shears Pty Ltd Ribozyme.
PH31293A (en) * 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
US5668292A (en) * 1994-09-26 1997-09-16 Carnegie Institution Of Washington Use of plant fatty acyl hydroxylases to produce hydroxylated fatty acids and derivatives in plants
US5834293A (en) * 1994-09-28 1998-11-10 Vanderbilt University Cytochrome P450 arachidonic acid epoxygenase genetic mutation associated with hypertension
SE9601236D0 (sv) 1996-03-29 1996-03-29 Sten Stymne Novel plant enzyme and use thereof

Also Published As

Publication number Publication date
JP2001518797A (ja) 2001-10-16
EP0975765A1 (en) 2000-02-02
IL132393A (en) 2010-11-30
EA004568B1 (ru) 2004-06-24
WO1998046762A1 (en) 1998-10-22
CA2286895C (en) 2010-07-13
DE69836133T2 (de) 2007-08-16
EP0975765B1 (en) 2006-10-11
DK0975765T3 (da) 2007-02-19
CA2286895A1 (en) 1998-10-22
CN100482797C (zh) 2009-04-29
BR9808676B1 (pt) 2010-10-05
PL336292A1 (en) 2000-06-19
US6329518B1 (en) 2001-12-11
EP0975765A4 (en) 2002-09-25
EA199900933A1 (ru) 2000-04-24
DE69836133D1 (de) 2006-11-23
MX9909476A (es) 2000-04-30
TR199902583T2 (xx) 2000-05-22
IL132393A0 (en) 2001-03-19
KR100711074B1 (ko) 2007-04-26
ES2275301T3 (es) 2007-06-01
KR20010006468A (ko) 2001-01-26
NZ500542A (en) 2000-11-24
JP4108765B2 (ja) 2008-06-25
CN1257541A (zh) 2000-06-21
PL194095B1 (pl) 2007-04-30
MX224646B (es) 2004-12-03
ATE342361T1 (de) 2006-11-15

Similar Documents

Publication Publication Date Title
BR9808676A (pt) Molécula de ácido nucleico isolada, construção genética, processo para alterar o nìvel de ácidos graxos epóxi em uma célula, tecido, órgão ou organismo e para produzir um polipeptìdeo epoxigenase enzimaticamente ativo e um ácido graxo epoxigenado, recombinante, polipeptìdeo recombinante, planta, e, molécula de anticorpo
ES2195993T3 (es) Metodo para inhibir la produccion de etileno en plantas.
BR9808528A (pt) Sintases de ácidos graxos em plantas e seu uso em métodos aperfeiçoados para produção de ácidos graxos de cadeia média
AR012399A1 (es) Una region regulatoria de 5&#39; de oleosiina para la modificacion de composicion lipida de semilla de planta
BG103797A (en) Composition and method for polynonsaturated fatty acid syntheses with a long chain
BR0011400A (pt) Sequência de ácido nucleico isolada, sequência de aminoácidos, cassete de expressão, vetor, organismo, planta transgênica, processos para preparar ácidos graxos insaturados, e para preparar triglicerìdeos, proteìna, ácido graxo insaturado, triglicerìdeo, e, uso de uma sequência de ácidos nucleicos, de ácidos graxos insaturados ou triglicerìdeos com um conteúdo aumentado de ácidos graxos insaturados, e de proteìnas
DE69133283D1 (de) Dna, die für pflanzliche thioesterasen kodiert
DE69636903D1 (de) Herstellung von 1,3-propandiol aus glycerol mit rekombinanten diol-dehydratase exprimierenden bakterien
DE69636225D1 (de) STIMULIERUNG der HOMOLOGEn REKOMBINATION IN pflanzlichen ORGANISMEN MITTELS REKOMBINATIONS FÖRDERNDER ENZYME
PL334530A1 (en) Novel genes specific in respect to n-axecetyl-l-phosphotricin, used to code amino acids deacetylase, their isolation and application
PE44399A1 (es) Procedimiento para la produccion de l-amino acido mediante fermentacion
HUP9904364A2 (hu) Módosított acil-ACP-deszaturáz
DE69935978D1 (de) Kulturmedium zur kultivierung tierischer zellen und verfahren zur herstellung von proteinen durch dessen verwendung
EP2325308A3 (en) Methods and materials for making and using transgenic dicamba-degrading organisms
CA2170761A1 (en) Lipid-Modified Serum Free Media
BR0013687A (pt) Sequências de ácido nucleico isolada, e de aminoácido, construção de ácido nucleico, vetor, organismo, vegetal transgênico, processos para a preparação de ácidos graxos insaturados, para a preparação de triglicerìdeos com um teor aumentado de ácidos graxos insaturados, para a preparação de ácidos graxos saturados, uso de uma sequência de ácido nucleico, uso de ácidos graxos insaturados ou saturados, e, enzima
BR9915881A (pt) Sequência de dna isolada, polipeptìdeo purificado e isolado, vetor de expressão recombinante, vetor de clonagem replicativo, método para regular a formação de éster alifático e/ou aromático em frutas, planta e material de propagação da mesma, planta de morango ou limão geneticamente modificada e material de propagação derivado da mesma, método para produzir ésteres aromáticos e/ou alifáticos em microorganismos, células de plantas ou plantas, anticorpo, kit diagnóstico, e, método para triar frutas
DE60312592D1 (de) Verfahren zur Herstellung von L-Lysin unter Verwendung Coryneformer Bakterien die ein attenuiertes Malat Enzym-gen enthalten
BR0213259A (pt) Método para produzir um composto bioativo apresentando uma bioatividade conhecida, e, células recombinantes
DE69837047D1 (de) Verfahren zur herstellung verzweigtkettiger fettsäuren mittels genetisch modifizierter pflanzen
BR0005307A (pt) Processo para a produção fermentativa de l-lisina usando bactérias coryneform
DE60235879D1 (de) Verfahren und materialien zur herstellung und anwendung transgener, dicamba abbauender organismen
Kim et al. Effect of prolonged starvation on the activities of malic enzyme and acetylcholinesterase in tissues of Japanese quail
EP1637606A3 (de) Triacylglycerol-Lipasen
BR0207818A (pt) Processo para a produção de vitamina e, construção de ácido nucléico, combinação de construções de ácido nucléico, organismo geneticamente modificado, uso do mesmo, processo para a produção de organismos geneticamente modificados, e, uso dos ácidos nucléicos, ou das construções de ácido nucléico, ou das combinações de construções de ácido nucléico

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Free format text: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU), BASF PLANT SCIENCE GMBH (DE)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 05/10/2010, OBSERVADAS AS CONDICOES LEGAIS. COM RESSALVA NO QUE INCIDIR NO ARTIGO 10, INCISO IX, DA LPI 9279/96.

B24H Lapse because of non-payment of annual fees (definitively: art 78 iv lpi)
B24F Patent annual fee: publication cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2257 DE 08/04/2014 POR TER SIDO INDEVIDA.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE AS 13A, 14A, 15A, 16A, 17A, 18A, 19A, 20A, 21A E 22A ANUIDADES.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2606 DE 15-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.