BR9713522A - Método de uso de inibidores da cicloxigenase-2 como agentes antiangiogênicos. - Google Patents
Método de uso de inibidores da cicloxigenase-2 como agentes antiangiogênicos.Info
- Publication number
- BR9713522A BR9713522A BR9713522A BR9713522A BR9713522A BR 9713522 A BR9713522 A BR 9713522A BR 9713522 A BR9713522 A BR 9713522A BR 9713522 A BR9713522 A BR 9713522A BR 9713522 A BR9713522 A BR 9713522A
- Authority
- BR
- Brazil
- Prior art keywords
- cyclooxygenase
- inhibitors
- antiangiogenic agents
- antiangiogenic
- agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3140496P | 1996-11-19 | 1996-11-19 | |
PCT/US1997/021489 WO1998022101A2 (en) | 1996-11-19 | 1997-11-19 | Method of using cyclooxygenase-2 inhibitors as anti-angiogenic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9713522A true BR9713522A (pt) | 2000-03-21 |
Family
ID=21859277
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9713522A BR9713522A (pt) | 1996-11-19 | 1997-11-19 | Método de uso de inibidores da cicloxigenase-2 como agentes antiangiogênicos. |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0941080A2 (sk) |
JP (1) | JP2001505564A (sk) |
KR (1) | KR20000053362A (sk) |
CN (1) | CN1247470A (sk) |
AU (1) | AU730211B2 (sk) |
BR (1) | BR9713522A (sk) |
CA (1) | CA2270469C (sk) |
CZ (1) | CZ176899A3 (sk) |
ID (1) | ID21979A (sk) |
IL (1) | IL129604A (sk) |
NO (1) | NO992309L (sk) |
NZ (1) | NZ335853A (sk) |
PL (2) | PL194717B1 (sk) |
RO (1) | RO118566B1 (sk) |
RU (1) | RU2268716C2 (sk) |
SK (1) | SK59999A3 (sk) |
TR (1) | TR199901703T2 (sk) |
UA (1) | UA70294C2 (sk) |
WO (1) | WO1998022101A2 (sk) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6515014B2 (en) | 1995-06-02 | 2003-02-04 | G. D. Searle & Co. | Thiophene substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors |
US6512121B2 (en) | 1998-09-14 | 2003-01-28 | G.D. Searle & Co. | Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors |
US6887893B1 (en) | 1997-12-24 | 2005-05-03 | Sankyo Company, Limited | Methods and compositions for treatment and prevention of tumors, tumor-related disorders and cachexia |
JP2002533387A (ja) * | 1998-12-23 | 2002-10-08 | ジー.ディー.サール & カンパニー | 腫瘍治療の複合療法としてインテグリン拮抗物質と一つ以上の抗腫瘍剤を使用する方法 |
US6833373B1 (en) | 1998-12-23 | 2004-12-21 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
US20030013739A1 (en) * | 1998-12-23 | 2003-01-16 | Pharmacia Corporation | Methods of using a combination of cyclooxygenase-2 selective inhibitors and thalidomide for the treatment of neoplasia |
WO2000053149A2 (en) * | 1999-03-10 | 2000-09-14 | G.D. Searle & Co. | Method and composition for administering a cyclooxygenase-2 inhibitor |
AU775305B2 (en) * | 1999-07-29 | 2004-07-29 | Tularik Inc. | Combination therapy using pentafluorobenzenesulfonamide and platin compound |
AU6469401A (en) | 2000-05-19 | 2001-11-26 | Serono Reproductive Biology In | Pharmaceutically active compounds and methods of use |
WO2002039958A2 (en) | 2000-11-03 | 2002-05-23 | Tularik Inc. | Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents |
KR100686537B1 (ko) * | 2001-12-28 | 2007-02-27 | 씨제이 주식회사 | 사이클로옥시게나제-2 의 저해제로서 선택성이 뛰어난디아릴 1,2,4-트리아졸 유도체 |
EP1530475A2 (en) * | 2002-07-17 | 2005-05-18 | Warner-Lambert Company LLC | Pharmaceutical compositions comprising an allosteric carboxylic inhibitor of matrix metalloproteinase-13 and a selective inhibitor of cyclooxygenase-2 |
KR100484525B1 (ko) * | 2002-10-15 | 2005-04-20 | 씨제이 주식회사 | 이소티아졸 유도체, 그 제조방법 및 약제학적 조성물 |
AT504159A1 (de) * | 2006-08-16 | 2008-03-15 | Marlyn Nutraceuticals Inc | Verwendung von proteasen |
RU2475257C1 (ru) * | 2011-06-22 | 2013-02-20 | Людмила Николаевна Третьяк | Средство для повышения адаптируемости организма к экстремальным условиям |
GB2496135B (en) * | 2011-11-01 | 2015-03-18 | Valirx Plc | Inhibitors of the interaction between a Src family kinase and an androgen receptor or estradiol receptor for treatment of endometriosis |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6027694A (en) * | 1993-01-15 | 1994-08-15 | G.D. Searle & Co. | Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
US5436265A (en) * | 1993-11-12 | 1995-07-25 | Merck Frosst Canada, Inc. | 1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents |
PL180717B1 (pl) * | 1993-11-30 | 2001-03-30 | Searle & Co | N o w e 1 -[4-(aminosulfonylo)fenylo]pirazolilobenzenosulfonamidy do leczenia stanów zapalnych PL PL PL PL PL PL PL |
US5521213A (en) * | 1994-08-29 | 1996-05-28 | Merck Frosst Canada, Inc. | Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2 |
EP0799218B1 (en) * | 1994-12-21 | 2003-02-19 | Merck Frosst Canada & Co. | Diaryl-2-(5h)-furanones as cox-2 inhibitors |
US5691374A (en) * | 1995-05-18 | 1997-11-25 | Merck Frosst Canada Inc. | Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors |
-
1997
- 1997-11-19 EP EP97949579A patent/EP0941080A2/en not_active Withdrawn
- 1997-11-19 AU AU72982/98A patent/AU730211B2/en not_active Ceased
- 1997-11-19 PL PL97373973A patent/PL194717B1/pl unknown
- 1997-11-19 CA CA002270469A patent/CA2270469C/en not_active Expired - Fee Related
- 1997-11-19 UA UA99063447A patent/UA70294C2/uk unknown
- 1997-11-19 SK SK599-99A patent/SK59999A3/sk unknown
- 1997-11-19 RU RU99112952/14A patent/RU2268716C2/ru not_active IP Right Cessation
- 1997-11-19 KR KR1019990704392A patent/KR20000053362A/ko not_active Application Discontinuation
- 1997-11-19 CZ CZ991768A patent/CZ176899A3/cs unknown
- 1997-11-19 NZ NZ335853A patent/NZ335853A/en not_active Application Discontinuation
- 1997-11-19 RO RO99-00572A patent/RO118566B1/ro unknown
- 1997-11-19 TR TR1999/01703T patent/TR199901703T2/xx unknown
- 1997-11-19 BR BR9713522A patent/BR9713522A/pt not_active Application Discontinuation
- 1997-11-19 IL IL12960497A patent/IL129604A/en not_active IP Right Cessation
- 1997-11-19 ID IDW990379A patent/ID21979A/id unknown
- 1997-11-19 JP JP52396098A patent/JP2001505564A/ja not_active Withdrawn
- 1997-11-19 WO PCT/US1997/021489 patent/WO1998022101A2/en not_active Application Discontinuation
- 1997-11-19 CN CN97181368A patent/CN1247470A/zh active Pending
-
1999
- 1999-04-30 PL PL333370A patent/PL191793B1/pl unknown
- 1999-05-12 NO NO992309A patent/NO992309L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TR199901703T2 (xx) | 2000-07-21 |
IL129604A (en) | 2004-08-31 |
PL194717B1 (pl) | 2007-06-29 |
WO1998022101A2 (en) | 1998-05-28 |
CA2270469A1 (en) | 1998-05-28 |
SK59999A3 (en) | 2000-01-18 |
RO118566B1 (ro) | 2003-07-30 |
CZ176899A3 (cs) | 1999-10-13 |
EP0941080A2 (en) | 1999-09-15 |
NZ335853A (en) | 2002-02-01 |
WO1998022101A3 (en) | 1998-06-25 |
CN1247470A (zh) | 2000-03-15 |
CA2270469C (en) | 2007-04-10 |
NO992309D0 (no) | 1999-05-12 |
PL191793B1 (pl) | 2006-07-31 |
ID21979A (id) | 1999-08-19 |
NO992309L (no) | 1999-05-12 |
UA70294C2 (en) | 2004-10-15 |
JP2001505564A (ja) | 2001-04-24 |
PL333370A1 (en) | 1999-12-06 |
AU730211B2 (en) | 2001-03-01 |
IL129604A0 (en) | 2000-02-29 |
KR20000053362A (ko) | 2000-08-25 |
RU2268716C2 (ru) | 2006-01-27 |
AU7298298A (en) | 1998-06-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE NAO ATENDE AO REQUISITO DE ATIVIDADE INVENTIVA ( ART. 8O COMBINADO COM ART. 13 DA LPI ). |
|
B15K | Others concerning applications: alteration of classification |
Free format text: ALTERADA DE INT.CL: A61K 31/00, A61K 31/45, A61P 35/00, A61P 15/00 Ipc: A61K 31/00 (2007.10), A61K 31/45 (2007.10), A61K 3 |