BR9708171A - Uso de derivados de 4-fenil-3,6-di-hidro-2h-piridila como bloqueadores de subtipo de receptor nmda - Google Patents
Uso de derivados de 4-fenil-3,6-di-hidro-2h-piridila como bloqueadores de subtipo de receptor nmdaInfo
- Publication number
- BR9708171A BR9708171A BR9708171A BR9708171A BR9708171A BR 9708171 A BR9708171 A BR 9708171A BR 9708171 A BR9708171 A BR 9708171A BR 9708171 A BR9708171 A BR 9708171A BR 9708171 A BR9708171 A BR 9708171A
- Authority
- BR
- Brazil
- Prior art keywords
- nmda receptor
- receptor subtype
- hydrogen
- dihydro
- phenyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96103636 | 1996-03-08 | ||
PCT/EP1997/000951 WO1997032581A1 (en) | 1996-03-08 | 1997-02-27 | Use of 4-phenyl-3,6-dihydro-2h-pyridyl derivatives as nmda receptor subtype blockers |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9708171A true BR9708171A (pt) | 1999-07-27 |
Family
ID=8222541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9708171A BR9708171A (pt) | 1996-03-08 | 1997-02-27 | Uso de derivados de 4-fenil-3,6-di-hidro-2h-piridila como bloqueadores de subtipo de receptor nmda |
Country Status (15)
Country | Link |
---|---|
US (1) | US5962472A (pt) |
EP (1) | EP0885004B1 (pt) |
JP (1) | JP3248917B2 (pt) |
KR (1) | KR100352358B1 (pt) |
CN (1) | CN1131031C (pt) |
AT (1) | ATE216883T1 (pt) |
AU (1) | AU717140B2 (pt) |
BR (1) | BR9708171A (pt) |
CA (1) | CA2248134A1 (pt) |
DE (1) | DE69712325T2 (pt) |
DK (1) | DK0885004T3 (pt) |
ES (1) | ES2174220T3 (pt) |
PT (1) | PT885004E (pt) |
TR (1) | TR199801774T2 (pt) |
WO (1) | WO1997032581A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1674087A1 (en) | 2000-10-02 | 2006-06-28 | Pfizer Products Inc. | Prophylactic use of n-methyl-d-aspartate (NMDA) antagonists |
WO2002072542A2 (en) * | 2001-03-08 | 2002-09-19 | Emory University | Ph-dependent nmda receptor antagonists |
US6951875B2 (en) * | 2001-10-29 | 2005-10-04 | Hoffmann-La Roche Inc. | Conjugated aromatic compounds with a pyridine substituent |
US7005432B2 (en) * | 2002-05-16 | 2006-02-28 | Hoffman-La Roche Inc. | Substituted imidazol-pyridazine derivatives |
US7671072B2 (en) * | 2003-11-26 | 2010-03-02 | Pfizer Inc. | Aminopyrazole derivatives as GSK-3 inhibitors |
KR20100045983A (ko) * | 2007-06-29 | 2010-05-04 | 에모리 유니버시티 | 신경보호를 위한 nmda 수용체 길항물질 |
MX2010009649A (es) * | 2008-03-27 | 2010-12-17 | Evotecv Neurosciences Gmbh | Metodos para tratar trastornos utilizando un antagonista selectivo del subtipo nr2b de nmda. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH543509A (de) * | 1968-12-24 | 1973-10-31 | Hoffmann La Roche | Verfahren zur Herstellung von aromatischen Äthern |
CH558354A (de) * | 1970-06-17 | 1975-01-31 | Hoffmann La Roche | Verfahren zur herstellung von aromatischen aethern. |
US3879405A (en) * | 1970-06-19 | 1975-04-22 | Hoffmann La Roche | Tetrahydropyridine derivatives |
CH547802A (de) * | 1970-06-19 | 1974-04-11 | Hoffmann La Roche | Verfahren zur herstellung von tetrahydropyridinderivaten. |
US5149817A (en) * | 1990-03-05 | 1992-09-22 | Shionogi & Co., Ltd. | Teirahydropyridine derivatives |
DE4325855A1 (de) * | 1993-08-02 | 1995-02-09 | Boehringer Ingelheim Kg | Neue Benzoesäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
DE4325885A1 (de) * | 1993-08-02 | 1995-02-09 | Basf Ag | Elektrolumineszierende Anordnung |
DE4410822A1 (de) * | 1994-03-24 | 1995-09-28 | Schering Ag | Neue Piperidin-Derivate |
US5698565A (en) * | 1995-06-09 | 1997-12-16 | Hoffmann-La Roche Inc. | Use of phenoxy-pyridine derivatives |
-
1997
- 1997-02-27 JP JP53141697A patent/JP3248917B2/ja not_active Expired - Fee Related
- 1997-02-27 PT PT97905107T patent/PT885004E/pt unknown
- 1997-02-27 WO PCT/EP1997/000951 patent/WO1997032581A1/en active IP Right Grant
- 1997-02-27 KR KR10-1998-0706936A patent/KR100352358B1/ko not_active IP Right Cessation
- 1997-02-27 CA CA002248134A patent/CA2248134A1/en not_active Abandoned
- 1997-02-27 TR TR1998/01774T patent/TR199801774T2/xx unknown
- 1997-02-27 BR BR9708171A patent/BR9708171A/pt not_active Application Discontinuation
- 1997-02-27 AU AU18782/97A patent/AU717140B2/en not_active Ceased
- 1997-02-27 AT AT97905107T patent/ATE216883T1/de not_active IP Right Cessation
- 1997-02-27 CN CN97192889A patent/CN1131031C/zh not_active Expired - Fee Related
- 1997-02-27 DE DE69712325T patent/DE69712325T2/de not_active Expired - Fee Related
- 1997-02-27 DK DK97905107T patent/DK0885004T3/da active
- 1997-02-27 ES ES97905107T patent/ES2174220T3/es not_active Expired - Lifetime
- 1997-02-27 EP EP97905107A patent/EP0885004B1/en not_active Expired - Lifetime
- 1997-03-07 US US08/813,523 patent/US5962472A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1131031C (zh) | 2003-12-17 |
ATE216883T1 (de) | 2002-05-15 |
PT885004E (pt) | 2002-08-30 |
DK0885004T3 (da) | 2002-08-19 |
CN1213304A (zh) | 1999-04-07 |
KR100352358B1 (ko) | 2003-03-10 |
TR199801774T2 (xx) | 1998-12-21 |
AU1878297A (en) | 1997-09-22 |
JP3248917B2 (ja) | 2002-01-21 |
EP0885004A1 (en) | 1998-12-23 |
KR19990087505A (ko) | 1999-12-27 |
US5962472A (en) | 1999-10-05 |
DE69712325D1 (de) | 2002-06-06 |
EP0885004B1 (en) | 2002-05-02 |
WO1997032581A1 (en) | 1997-09-12 |
AU717140B2 (en) | 2000-03-16 |
ES2174220T3 (es) | 2002-11-01 |
JP2000507542A (ja) | 2000-06-20 |
CA2248134A1 (en) | 1997-09-12 |
DE69712325T2 (de) | 2002-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, COM BASE NOS ARTIGOS 8 E 11 DA LPI E DADO COMO CONCLUIDO O EXAME. |
|
B12B | Appeal against refusal [chapter 12.2 patent gazette] |