BR9509634A - Solução aquosa concentrada estável ao armazenamento para infusao uso da mesma e processos de preparação da mesma de tratamento de um paciente necessitando de um inibidor de trombina e de estabilização de um inibidor de trombina ativo - Google Patents

Solução aquosa concentrada estável ao armazenamento para infusao uso da mesma e processos de preparação da mesma de tratamento de um paciente necessitando de um inibidor de trombina e de estabilização de um inibidor de trombina ativo

Info

Publication number
BR9509634A
BR9509634A BR9509634A BR9509634A BR9509634A BR 9509634 A BR9509634 A BR 9509634A BR 9509634 A BR9509634 A BR 9509634A BR 9509634 A BR9509634 A BR 9509634A BR 9509634 A BR9509634 A BR 9509634A
Authority
BR
Brazil
Prior art keywords
thrombin inhibitor
infusion
patient
treatment
need
Prior art date
Application number
BR9509634A
Other languages
English (en)
Inventor
Ulla Stejernfelt
Mats Sundgren
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of BR9509634A publication Critical patent/BR9509634A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR9509634A 1994-11-08 1995-10-19 Solução aquosa concentrada estável ao armazenamento para infusao uso da mesma e processos de preparação da mesma de tratamento de um paciente necessitando de um inibidor de trombina e de estabilização de um inibidor de trombina ativo BR9509634A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9403831A SE504185C2 (sv) 1994-11-08 1994-11-08 Lagringsstabil vattenlösning för infusion av trombininhibitorer
PCT/SE1995/001228 WO1996014084A1 (en) 1994-11-08 1995-10-19 A storage stable water solution for infusion containing a thrombin inhibitor

Publications (1)

Publication Number Publication Date
BR9509634A true BR9509634A (pt) 1998-01-06

Family

ID=20395892

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9509634A BR9509634A (pt) 1994-11-08 1995-10-19 Solução aquosa concentrada estável ao armazenamento para infusao uso da mesma e processos de preparação da mesma de tratamento de um paciente necessitando de um inibidor de trombina e de estabilização de um inibidor de trombina ativo

Country Status (31)

Country Link
US (1) US5830865A (pt)
EP (1) EP0789585B1 (pt)
JP (1) JPH10508598A (pt)
KR (1) KR100416677B1 (pt)
CN (1) CN1090508C (pt)
AT (1) ATE205399T1 (pt)
AU (1) AU695719B2 (pt)
BR (1) BR9509634A (pt)
CA (1) CA2203396A1 (pt)
CZ (1) CZ287256B6 (pt)
DE (1) DE69522702T2 (pt)
DK (1) DK0789585T3 (pt)
EE (1) EE9700218A (pt)
ES (1) ES2163528T3 (pt)
FI (1) FI971949A0 (pt)
HU (1) HU217073B (pt)
IL (1) IL115879A (pt)
IS (1) IS4468A (pt)
MX (1) MX9703339A (pt)
MY (1) MY112593A (pt)
NO (1) NO322048B1 (pt)
NZ (1) NZ295492A (pt)
PL (1) PL320342A1 (pt)
PT (1) PT789585E (pt)
RU (1) RU2164803C2 (pt)
SE (1) SE504185C2 (pt)
SK (1) SK53597A3 (pt)
TR (1) TR199501391A2 (pt)
TW (1) TW407057B (pt)
WO (1) WO1996014084A1 (pt)
ZA (1) ZA959377B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984627B1 (en) * 1993-06-03 2006-01-10 Astrazeneca Ab Peptide derivatives
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
AR005245A1 (es) * 1995-12-21 1999-04-28 Astrazeneca Ab Prodrogas de inhibidores de trombina, una formulación farmaceutica que las comprende, el uso de dichas prodrogas para la manufactura de un medicamento y un procedimiento para su preparacion
SE9802974D0 (sv) * 1998-09-03 1998-09-03 Astra Ab New crystalline forms
US6462021B1 (en) 2000-11-06 2002-10-08 Astrazeneca Ab Use of low molecular weight thrombin inhibitor
ES2543588T3 (es) 2002-12-03 2015-08-20 Pharmacyclics Llc Derivados de 2-(2-hidroxibifenil-3-il)-1H-benzoimidazol-5-carboxamidina como inhibidores del factor VIIa
US7345093B2 (en) * 2004-04-27 2008-03-18 Formatech, Inc. Methods of enhancing solubility of compounds
US20110070294A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods for the Administration of Drugs Using Liposomes
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
WO2011038073A1 (en) 2009-09-23 2011-03-31 Formatech, Inc. Methods for the preparation of liposomes comprising docetaxel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9103612D0 (sv) * 1991-12-04 1991-12-04 Astra Ab New peptide derivatives
US5466131A (en) * 1994-03-22 1995-11-14 Micropump Corporation Multiple-chamber gear pump with hydraulically connected chambers

Also Published As

Publication number Publication date
NO322048B1 (no) 2006-08-07
EP0789585B1 (en) 2001-09-12
TW407057B (en) 2000-10-01
HU217073B (hu) 1999-11-29
SE9403831D0 (sv) 1994-11-08
RU2164803C2 (ru) 2001-04-10
CZ287256B6 (en) 2000-10-11
CN1090508C (zh) 2002-09-11
TR199501391A2 (tr) 1996-06-21
FI971949A (fi) 1997-05-07
IS4468A (is) 1997-04-21
AU3884695A (en) 1996-05-31
IL115879A0 (en) 1996-01-31
SE9403831L (sv) 1996-05-09
PL320342A1 (en) 1997-09-29
CZ129497A3 (cs) 1998-02-18
US5830865A (en) 1998-11-03
KR970706844A (ko) 1997-12-01
CA2203396A1 (en) 1996-05-17
MY112593A (en) 2001-07-31
SK53597A3 (en) 1998-07-08
ATE205399T1 (de) 2001-09-15
DE69522702T2 (de) 2002-07-11
DK0789585T3 (da) 2001-11-12
EE9700218A (et) 1998-02-16
EP0789585A1 (en) 1997-08-20
CN1162921A (zh) 1997-10-22
NO972065D0 (no) 1997-05-05
FI971949A0 (fi) 1997-05-07
PT789585E (pt) 2002-01-30
NO972065L (no) 1997-05-05
MX9703339A (es) 1997-07-31
ZA959377B (en) 1996-05-08
KR100416677B1 (ko) 2004-06-16
AU695719B2 (en) 1998-08-20
JPH10508598A (ja) 1998-08-25
HUT77560A (hu) 1998-06-29
DE69522702D1 (de) 2001-10-18
SE504185C2 (sv) 1996-12-02
WO1996014084A1 (en) 1996-05-17
NZ295492A (en) 1998-06-26
IL115879A (en) 2001-08-08
ES2163528T3 (es) 2002-02-01

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]