BR9406613A - Composto éster ou amida metabolicamente lábil do mesmo processo para a preparação de um composto e composição farmacêutica - Google Patents
Composto éster ou amida metabolicamente lábil do mesmo processo para a preparação de um composto e composição farmacêuticaInfo
- Publication number
- BR9406613A BR9406613A BR9406613A BR9406613A BR9406613A BR 9406613 A BR9406613 A BR 9406613A BR 9406613 A BR9406613 A BR 9406613A BR 9406613 A BR9406613 A BR 9406613A BR 9406613 A BR9406613 A BR 9406613A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- preparation
- pharmaceutical composition
- same process
- metabolically labile
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Electroluminescent Light Sources (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939306453A GB9306453D0 (en) | 1993-03-29 | 1993-03-29 | Heterocyclic derivatives |
| GB939325605A GB9325605D0 (en) | 1993-12-15 | 1993-12-15 | Heterocyclic derivatives |
| PCT/GB1994/000647 WO1994022834A1 (en) | 1993-03-29 | 1994-03-28 | Heterocyclic derivatives as platelet aggregation inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9406613A true BR9406613A (pt) | 1996-02-06 |
Family
ID=26302668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9406613A BR9406613A (pt) | 1993-03-29 | 1994-03-28 | Composto éster ou amida metabolicamente lábil do mesmo processo para a preparação de um composto e composição farmacêutica |
Country Status (26)
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750754A (en) * | 1993-03-29 | 1998-05-12 | Zeneca Limited | Heterocyclic compounds |
| IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
| SK79797A3 (en) * | 1994-12-23 | 1997-11-05 | Thomae Gmbh Dr K | Piperazine derivatives, medicaments containing the same, their use and process for preparing the same |
| US5700801A (en) * | 1994-12-23 | 1997-12-23 | Karl Thomae, Gmbh | Piperazine derivatives, pharmaceutical compositions containing these compounds, their use and processes for preparing them |
| BR9606409A (pt) * | 1995-06-01 | 1997-09-30 | Zeneca Ltd | Composto opticamente ativo composição farmacêutica processos para inibir agregação de plaqueta em um animal de sangue quente ligação de fibrinogênio a gpiib/iia em um animal de sangue quente e eventos trombóticos que acompanham agnina instável em animal de sangue quente e uso do composto opticamante ativo |
| FR2734818B1 (fr) * | 1995-06-01 | 1998-07-10 | Zeneca Ltd | Acide (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazine-1-yl- phenoxy}-butyrique, procede pour sa preparation et composition pharmaceutique le contenant |
| DE19524765A1 (de) * | 1995-07-07 | 1997-01-09 | Boehringer Mannheim Gmbh | Neue Oxazolidinonderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| PT874836E (pt) * | 1995-11-17 | 2003-02-28 | Warner Lambert Co | Inibidores com sulfonamida de metaloproteinases de matriz |
| GB9525620D0 (en) * | 1995-12-15 | 1996-02-14 | Glaxo Group Ltd | Chemical compounds |
| GB9602166D0 (en) * | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
| US6313127B1 (en) * | 1996-02-02 | 2001-11-06 | Zeneca Limited | Heterocyclic compounds useful as pharmaceutical agents |
| GB9604242D0 (en) | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
| AU712082B2 (en) * | 1996-02-28 | 1999-10-28 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5780480A (en) * | 1996-02-28 | 1998-07-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| AU2044297A (en) * | 1996-03-29 | 1997-10-22 | Meiji Seika Kaisha Ltd. | Novel heterocyclic compounds having platelet aggregation inhibitory effects |
| JP2000514427A (ja) * | 1996-06-28 | 2000-10-31 | メルク エンド カンパニー インコーポレーテッド | フィブリノーゲンレセプター拮抗薬プロドラッグ |
| CA2258093A1 (en) * | 1996-06-28 | 1998-01-08 | Mark E. Duggan | Fibrinogen receptor antagonists |
| US5932582A (en) * | 1996-06-28 | 1999-08-03 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
| US5990107A (en) * | 1996-06-28 | 1999-11-23 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
| US5854245A (en) * | 1996-06-28 | 1998-12-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| GB9821483D0 (en) | 1998-10-03 | 1998-11-25 | Glaxo Group Ltd | Chemical compounds |
| UA56197C2 (uk) * | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
| US5945545A (en) * | 1996-12-13 | 1999-08-31 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US6440972B1 (en) | 1997-02-13 | 2002-08-27 | Zeneca Limited | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
| DK0966462T3 (da) | 1997-02-13 | 2003-09-22 | Astrazeneca Ab | Heterocykliske forbindelser, der er egnede som oxidosqualencyklaseinhibitorer |
| GB9715895D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic compounds |
| US6166069A (en) * | 1998-05-12 | 2000-12-26 | American Home Products Corporation | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
| US6451827B2 (en) | 1998-05-12 | 2002-09-17 | Wyeth | 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia |
| US6232322B1 (en) | 1998-05-12 | 2001-05-15 | American Home Products Corporation | Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
| US6110963A (en) * | 1998-05-12 | 2000-08-29 | American Home Products Corporation | Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
| US6221902B1 (en) | 1998-05-12 | 2001-04-24 | American Home Products Corporation | Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
| CA2331056A1 (en) | 1998-05-12 | 1999-12-02 | Wyeth | 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia |
| US6699896B1 (en) | 1998-05-12 | 2004-03-02 | Wyeth | Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
| DE69917278T2 (de) * | 1998-07-31 | 2005-05-19 | Eli Lilly And Co., Indianapolis | Heterocyclyl sulphonamid derivate |
| GB9902989D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Heterocyclic derivatives |
| EP1173408B1 (en) * | 1999-04-19 | 2005-07-20 | Coelacanth Corporation | Ppar-(gamma) agonists as agents for the treatment of type ii diabetes |
| US6310081B1 (en) | 1999-05-10 | 2001-10-30 | American Home Products Corporation | Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
| ATE502928T1 (de) | 2000-11-01 | 2011-04-15 | Millennium Pharm Inc | Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung |
| DE202011000090U1 (de) | 2011-01-14 | 2011-04-21 | E-LEAD ELECTRONIC CO., LTD., Shengang Shiang | Fahrzeug-Audiosystem mit auswechselbarem Plug-In-Computer |
| FI3684767T3 (fi) | 2017-09-22 | 2024-07-22 | Jubilant Epipad LLC | Heterosyklisiä yhdisteitä pad:n estäjinä |
| US11426412B2 (en) | 2017-10-18 | 2022-08-30 | Jubilant Epipad LLC | Imidazo-pyridine compounds as PAD inhibitors |
| SG11202004143XA (en) | 2017-11-06 | 2020-06-29 | Jubilant Prodel LLC | Pyrimidine derivatives as inhibitors of pd1/pd-l1 activation |
| RS65576B1 (sr) | 2017-11-24 | 2024-06-28 | Jubilant Episcribe Llc | Heterociklična jedinjenja kao inhibitori prmt5 |
| JP7279063B6 (ja) | 2018-03-13 | 2024-02-15 | ジュビラント プローデル エルエルシー | Ｐｄ１／ｐｄ－ｌ１相互作用／活性化の阻害剤としての二環式化合物 |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3875165A (en) * | 1973-02-22 | 1975-04-01 | Wyeth John & Brother Ltd | (4-Quinolylamino)-(N-piperidyl)benzamides and N-{8 (quinolylamino)-benzoyl{9 piperidines |
| GB1474296A (en) * | 1975-01-23 | 1977-05-18 | Wyeth John & Brother Ltd | 4-aminoquinoline derivatives |
| JPS57183738A (en) * | 1981-05-06 | 1982-11-12 | Yamanouchi Pharmaceut Co Ltd | Aromatic carboxylic acid derivative |
| ZA825719B (en) * | 1981-09-03 | 1983-06-29 | Recordati Chem Pharm | Alkanoylanilides |
| EP0100158A3 (en) * | 1982-07-28 | 1985-03-27 | The Upjohn Company | (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters |
| US4613598A (en) * | 1984-03-13 | 1986-09-23 | Mitsubishi Chemical Industries Limited | Piperazine derivatives and their acid addition salts |
| CA1252788A (en) * | 1985-03-12 | 1989-04-18 | William J. Coates | Pyridazinone derivatives |
| GB8603120D0 (en) * | 1986-02-07 | 1986-03-12 | Pfizer Ltd | Anti-dysrhythmia agents |
| GB8609630D0 (en) * | 1986-04-19 | 1986-05-21 | Pfizer Ltd | Anti-arrhythmia agents |
| EP0264883A3 (en) * | 1986-10-21 | 1990-04-04 | Banyu Pharmaceutical Co., Ltd. | Substituted pyridine derivatives |
| MY104343A (en) * | 1987-11-23 | 1994-03-31 | Janssen Pharmaceutica Nv | Novel pyridizinamine deravatives |
| GB8819307D0 (en) * | 1988-08-13 | 1988-09-14 | Pfizer Ltd | Antiarrhythmic agents |
| US5039805A (en) * | 1988-12-08 | 1991-08-13 | Hoffmann-La Roche Inc. | Novel benzoic and phenylacetic acid derivatives |
| US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
| CA2008116C (en) * | 1989-02-23 | 2001-11-20 | Thomas Weller | Glycine derivatives |
| DE4134467A1 (de) * | 1991-10-18 | 1993-04-22 | Thomae Gmbh Dr K | Heterobiarylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| US5318899A (en) * | 1989-06-16 | 1994-06-07 | Cor Therapeutics, Inc. | Platelet aggregation inhibitors |
| CA2060326C (en) * | 1989-07-25 | 2003-10-21 | Jackson Boling Hester, Jr. | Antiarrhythmic tertiary amine-alkenyl-phenyl-alkanesulfonamides |
| US5051405A (en) * | 1989-10-10 | 1991-09-24 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Anti-thrombotic peptides and pseudopeptides |
| CA2037153A1 (en) * | 1990-03-09 | 1991-09-10 | Leo Alig | Acetic acid derivatives |
| GB9007751D0 (en) * | 1990-04-05 | 1990-06-06 | Ciba Geigy Ag | Novel platelet-aggregation inhibitors |
| US5252735A (en) * | 1990-06-29 | 1993-10-12 | The Upjohn Company | Antiatherosclerotic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones |
| US5264420A (en) * | 1990-09-27 | 1993-11-23 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| IL99539A0 (en) * | 1990-09-27 | 1992-08-18 | Merck & Co Inc | Fibrinogen receptor antagonists and pharmaceutical compositions containing them |
| NZ239876A (en) * | 1990-09-27 | 1993-12-23 | Merck & Co Inc | Glycyl-b-alanine derivatives and pharmaceutical compositions thereof. |
| IL99537A (en) * | 1990-09-27 | 1995-11-27 | Merck & Co Inc | Fibrinogen receptor antagonists and pharmaceutical compositions containing them |
| NZ239846A (en) * | 1990-09-27 | 1994-11-25 | Merck & Co Inc | Sulphonamide derivatives and pharmaceutical compositions thereof |
| DE4102024A1 (de) * | 1991-01-24 | 1992-07-30 | Thomae Gmbh Dr K | Biphenylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| WO1992013552A1 (en) * | 1991-02-05 | 1992-08-20 | Smithkline Beecham Corporation | Anti-aggregatory peptides containing an aromatic ester or amide |
| DE4107857A1 (de) * | 1991-03-12 | 1992-09-17 | Thomae Gmbh Dr K | Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| UA39849C2 (uk) * | 1991-03-26 | 2001-07-16 | Ф.Хоффманн-Ля Рош Аг | ПОХІДНІ N-АЦИЛ-<font face="Symbol">a</font>-АМІНОКИСЛОТИ АБО ЇХ ФІЗІОЛОГІЧНО ПРИЙНЯТНІ СОЛІ, ПРОСТІ АБО СКЛАДНІ ЕФІРИ, АМІДИ АБО ЇХ ГІДРАТИ ЯК ФАРМАЦЕВТИЧНО АКТИВНІ РЕЧОВИНИ |
| MX9201416A (es) * | 1991-03-28 | 1992-10-01 | Rhone Poulenc Rorer Int | Peptidos y pseudopeptidos antitromboticos. |
| JPH08503920A (ja) * | 1991-04-11 | 1996-04-30 | ローヌ−プーラン ローラー インターナショナル（ホウルディングス） インコーポレイテッド | 抗血栓ペプチドおよび偽ペプチド誘導体 |
| FI934894A0 (fi) * | 1991-05-07 | 1993-11-05 | Merck & Co Inc | Fibrinogenreceptorantagonister |
| US5321034A (en) * | 1991-05-07 | 1994-06-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| DK0513675T3 (da) * | 1991-05-13 | 1996-09-30 | Fujisawa Pharmaceutical Co | Hidtil ukendt peptidforbindelse samt fremgangsmåde til fremstilling deraf |
| JPH05213884A (ja) * | 1991-06-14 | 1993-08-24 | Upjohn Co:The | 新規な４−アミノキノリン類およびこれを有効成分とする高血圧・鬱血性心不全の予防・治療剤 |
| DE4124942A1 (de) * | 1991-07-27 | 1993-01-28 | Thomae Gmbh Dr K | 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE4127404A1 (de) * | 1991-08-19 | 1993-02-25 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| AU646966B2 (en) * | 1991-08-23 | 1994-03-10 | Takeda Chemical Industries Ltd. | 2-piperazinone compounds, their production and use |
| WO1993008164A1 (en) * | 1991-10-15 | 1993-04-29 | G.D. Searle & Co. | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors |
| US5254573A (en) * | 1991-10-15 | 1993-10-19 | Monsanto Company | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors |
| US5239113A (en) * | 1991-10-15 | 1993-08-24 | Monsanto Company | Substituted β-amino acid derivatives useful as platelet aggregation inhibitors and intermediates thereof |
| GB9122016D0 (en) * | 1991-10-16 | 1991-11-27 | Glaxo Group Ltd | Chemical compounds |
| US5250679A (en) * | 1991-10-18 | 1993-10-05 | Genentech, Inc. | Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor |
| US5272158A (en) * | 1991-10-29 | 1993-12-21 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| WO1993010091A2 (en) * | 1991-11-14 | 1993-05-27 | Glaxo Group Limited | Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation |
| US5424334A (en) * | 1991-12-19 | 1995-06-13 | G. D. Searle & Co. | Peptide mimetic compounds useful as platelet aggregation inhibitors |
| EP0623120A1 (en) * | 1992-01-21 | 1994-11-09 | Glaxo Group Limited | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation |
| US5264457A (en) * | 1992-02-14 | 1993-11-23 | G. D. Searle & Co. | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors |
| US5227490A (en) * | 1992-02-21 | 1993-07-13 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| HUT63609A (en) * | 1992-03-10 | 1993-09-28 | Sandoz Ag | Process for producing new derivatives and isosters of beta-amino acids and pharmaceutical compositions comprising such compounds |
| DE4212304A1 (de) * | 1992-04-13 | 1993-10-14 | Cassella Ag | Asparaginsäurederivate, ihre Herstellung und Verwendung |
| GB9208740D0 (en) * | 1992-04-23 | 1992-06-10 | Glaxo Group Ltd | Chemical compounds |
| DE4213634A1 (de) * | 1992-04-24 | 1993-10-28 | Cassella Ag | 2,4-Dioxo-imidazolidin-Derivate |
| DE4219158A1 (de) * | 1992-06-11 | 1993-12-16 | Thomae Gmbh Dr K | Biphenylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| US5726192A (en) * | 1992-12-29 | 1998-03-10 | Smithkline Beecham Corporation | Platelet aggregation inhibiting compounds |
| TW301607B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1993-03-09 | 1997-04-01 | Takeda Pharm Industry Co Ltd |
-
1994
- 1994-03-28 AU AU62889/94A patent/AU692438B2/en not_active Ceased
- 1994-03-28 DE DE69411900T patent/DE69411900T2/de not_active Expired - Fee Related
- 1994-03-28 TW TW083102802A patent/TW276254B/zh active
- 1994-03-28 JP JP6521810A patent/JPH08508291A/ja active Pending
- 1994-03-28 PT PT97117909T patent/PT825184E/pt unknown
- 1994-03-28 CN CN94191664A patent/CN1120334A/zh active Pending
- 1994-03-28 AT AT97117909T patent/ATE202345T1/de not_active IP Right Cessation
- 1994-03-28 EP EP94910494A patent/EP0691959B1/en not_active Expired - Lifetime
- 1994-03-28 DK DK97117909T patent/DK0825184T3/da active
- 1994-03-28 HU HU9502290A patent/HUT72088A/hu unknown
- 1994-03-28 EP EP97117909A patent/EP0825184B1/en not_active Expired - Lifetime
- 1994-03-28 GB GB9406143A patent/GB9406143D0/en active Pending
- 1994-03-28 US US08/218,171 patent/US5556977A/en not_active Expired - Fee Related
- 1994-03-28 ES ES94910494T patent/ES2119184T3/es not_active Expired - Lifetime
- 1994-03-28 WO PCT/GB1994/000647 patent/WO1994022834A1/en not_active Application Discontinuation
- 1994-03-28 CA CA002156070A patent/CA2156070A1/en not_active Abandoned
- 1994-03-28 NZ NZ262941A patent/NZ262941A/en unknown
- 1994-03-28 FI FI954616A patent/FI954616A7/fi unknown
- 1994-03-28 BR BR9406613A patent/BR9406613A/pt not_active Application Discontinuation
- 1994-03-28 IL IL10914494A patent/IL109144A/xx not_active IP Right Cessation
- 1994-03-28 SK SK1208-95A patent/SK120895A3/sk unknown
- 1994-03-28 AT AT94910494T patent/ATE168678T1/de not_active IP Right Cessation
- 1994-03-28 KR KR1019950704314A patent/KR100231089B1/ko not_active Expired - Fee Related
- 1994-03-28 ZW ZW4294A patent/ZW4294A1/xx unknown
- 1994-03-28 DK DK94910494T patent/DK0691959T3/da active
- 1994-03-28 CZ CZ952509A patent/CZ250995A3/cs unknown
- 1994-03-28 ES ES97117909T patent/ES2159798T3/es not_active Expired - Lifetime
- 1994-03-28 DE DE69427548T patent/DE69427548T2/de not_active Expired - Fee Related
- 1994-03-28 PL PL94310889A patent/PL310889A1/xx unknown
-
1995
- 1995-06-13 HU HU95P/P00193P patent/HU211336A9/hu unknown
- 1995-09-28 NO NO953837A patent/NO305244B1/no not_active IP Right Cessation
-
1998
- 1998-08-27 GR GR980401930T patent/GR3027751T3/el unknown
-
2001
- 2001-09-18 GR GR20010401498T patent/GR3036640T3/el not_active IP Right Cessation
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