BR9302737A - Derivados de tiazolivinilfenila,processo para a preparacao de um composto,medicamento,uso e processos para tratar ou prevenir asma bronquica - Google Patents
Derivados de tiazolivinilfenila,processo para a preparacao de um composto,medicamento,uso e processos para tratar ou prevenir asma bronquicaInfo
- Publication number
- BR9302737A BR9302737A BR9302737A BR9302737A BR9302737A BR 9302737 A BR9302737 A BR 9302737A BR 9302737 A BR9302737 A BR 9302737A BR 9302737 A BR9302737 A BR 9302737A BR 9302737 A BR9302737 A BR 9302737A
- Authority
- BR
- Brazil
- Prior art keywords
- thiazolivinylphenyl
- medication
- treat
- derivatives
- processes
- Prior art date
Links
- 208000006673 asthma Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6539—Five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/907,987 US5273986A (en) | 1992-07-02 | 1992-07-02 | Cycloalkylthiazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9302737A true BR9302737A (pt) | 1994-02-08 |
Family
ID=25424972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9302737A BR9302737A (pt) | 1992-07-02 | 1993-07-01 | Derivados de tiazolivinilfenila,processo para a preparacao de um composto,medicamento,uso e processos para tratar ou prevenir asma bronquica |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US5273986A (pt) |
| EP (1) | EP0577003A1 (pt) |
| JP (1) | JPH0680654A (pt) |
| KR (1) | KR940005602A (pt) |
| CN (1) | CN1087086A (pt) |
| AU (1) | AU667107B2 (pt) |
| BR (1) | BR9302737A (pt) |
| CA (1) | CA2099295A1 (pt) |
| CZ (1) | CZ133493A3 (pt) |
| FI (1) | FI933037A (pt) |
| HU (1) | HUT72747A (pt) |
| IL (1) | IL106141A0 (pt) |
| MX (1) | MX9303958A (pt) |
| NO (1) | NO932399L (pt) |
| NZ (1) | NZ247988A (pt) |
| PL (1) | PL299544A1 (pt) |
| UY (1) | UY23609A1 (pt) |
| ZA (1) | ZA934603B (pt) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830854A (en) * | 1992-12-14 | 1998-11-03 | Merck Sharp & Dohme, Limited | Method of treating cystic fibrosis using a tachykinin receptor antagonist |
| WO1996008479A1 (en) * | 1994-09-13 | 1996-03-21 | F. Hoffmann-La Roche Ag | A process of making (e)-4-[3-[2-(4-cycloalkyl-2-thiazolyl)ethenyl]phenyl]amino-2,2-alkyldiyl-4-oxobutanoic acid |
| KR100386392B1 (ko) * | 1994-10-14 | 2003-10-11 | 야마노우치세이야쿠 가부시키가이샤 | 아졸유도체및이를포함하는약제학적조성물 |
| JPH11506425A (ja) * | 1995-04-21 | 1999-06-08 | 第一製薬株式会社 | エチニルチアゾール誘導体 |
| SE9804212D0 (sv) * | 1998-12-04 | 1998-12-04 | Astra Pharma Prod | Compounds |
| EP1389463A4 (en) * | 2001-04-26 | 2008-09-17 | Daiichi Seiyaku Co | MEDICAMENT FOR INHIBITING A DRUG REMOVAL PUMP |
| US7056917B2 (en) * | 2001-04-26 | 2006-06-06 | Daiichi Pharmaceutical Co., Ltd. | Drug efflux pump inhibitor |
| SE0102299D0 (sv) * | 2001-06-26 | 2001-06-26 | Astrazeneca Ab | Compounds |
| SE0102764D0 (sv) * | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
| GB0226930D0 (en) | 2002-11-19 | 2002-12-24 | Astrazeneca Ab | Chemical compounds |
| EP2048137A1 (en) * | 2004-02-18 | 2009-04-15 | AstraZeneca AB | Benzamide derivatives and their use as glucokinase activating agents. |
| KR20070007104A (ko) * | 2004-02-18 | 2007-01-12 | 아스트라제네카 아베 | 화합물 |
| TW200600086A (en) * | 2004-06-05 | 2006-01-01 | Astrazeneca Ab | Chemical compound |
| GB0423043D0 (en) * | 2004-10-16 | 2004-11-17 | Astrazeneca Ab | Compounds |
| CA2581619A1 (en) | 2004-10-16 | 2006-04-20 | Astrazeneca Ab | Process for making phenoxy benzamide compounds |
| GB0423044D0 (en) * | 2004-10-16 | 2004-11-17 | Astrazeneca Ab | Compounds |
| US20110059941A1 (en) * | 2005-05-24 | 2011-03-10 | Peter William Rodney Caulkett | 2-phenyl substituted imidazol [4,5b] pyridine/pyrazine and purine derivatives as glucokinase modulators |
| TW200714597A (en) * | 2005-05-27 | 2007-04-16 | Astrazeneca Ab | Chemical compounds |
| BRPI0622262A2 (pt) * | 2005-07-09 | 2011-08-09 | Astrazeneca Ab | composto, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, processo para a preparação de um composto |
| US20110053910A1 (en) * | 2005-07-09 | 2011-03-03 | Mckerrecher Darren | 2 -heterocyclyloxybenzoyl amino heterocyclyl compounds as modulators of glucokinase for the treatment of type 2 diabetes |
| EP2027113A1 (en) * | 2005-07-09 | 2009-02-25 | AstraZeneca AB | Heteroaryl benzamide derivatives for use as glk activators in the treatment of diabetes |
| US9202182B2 (en) * | 2005-08-11 | 2015-12-01 | International Business Machines Corporation | Method and system for analyzing business architecture |
| TW200738621A (en) * | 2005-11-28 | 2007-10-16 | Astrazeneca Ab | Chemical process |
| TW200825063A (en) * | 2006-10-23 | 2008-06-16 | Astrazeneca Ab | Chemical compounds |
| TW200825060A (en) * | 2006-10-26 | 2008-06-16 | Astrazeneca Ab | Chemical compounds |
| WO2008075073A1 (en) * | 2006-12-21 | 2008-06-26 | Astrazeneca Ab | Novel crystalline compound useful as glk activator |
| WO2010015849A2 (en) | 2008-08-04 | 2010-02-11 | Astrazeneca Ab | Therapeutic agents 414 |
| GB0902406D0 (en) * | 2009-02-13 | 2009-04-01 | Astrazeneca Ab | Crystalline polymorphic form |
| GB0902434D0 (en) * | 2009-02-13 | 2009-04-01 | Astrazeneca Ab | Chemical process |
| AR076220A1 (es) | 2009-04-09 | 2011-05-26 | Astrazeneca Ab | Derivados de pirazol [4,5 - e] pirimidina |
| AR076221A1 (es) | 2009-04-09 | 2011-05-26 | Astrazeneca Ab | Derivado de pirazol [4,5-e] pirimidina y su uso para tratar diabetes y obesidad |
| AU2010302584B2 (en) | 2009-10-02 | 2015-09-10 | Avexxin As | Anti inflammatory 2-oxothiazoles and 2 -oxooxazoles |
| KR102268357B1 (ko) | 2013-01-29 | 2021-06-23 | 아벡신 에이에스 | 항염증성 및 항종양성 2-옥소티아졸 및 2-옥소티오펜 화합물 |
| GB201413695D0 (en) | 2014-08-01 | 2014-09-17 | Avexxin As | Compound |
| GB201604318D0 (en) | 2016-03-14 | 2016-04-27 | Avexxin As | Combination therapy |
| WO2019148005A1 (en) * | 2018-01-26 | 2019-08-01 | Nurix Therapeutics, Inc. | Inhibitors of cbl-b and methods of use thereof |
| WO2020210508A1 (en) | 2019-04-09 | 2020-10-15 | Nurix Therapeutics, Inc. | 3-substituted piperidine compounds for cbl-b inhibition, and use of a cbl-b inhibitor in combination with a cancer vaccine and/or oncolytic virus |
| CN114206855A (zh) | 2019-05-17 | 2022-03-18 | 紐力克斯治疗公司 | 用于Cbl-b抑制的氰基环丁基类化合物及其用途 |
| CA3214729A1 (en) | 2021-04-08 | 2022-10-13 | Marilena GALLOTTA | Combination therapies with cbl-b inhibitor compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62142168A (ja) * | 1985-10-16 | 1987-06-25 | Mitsubishi Chem Ind Ltd | チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤 |
| JPS63258854A (ja) * | 1987-04-16 | 1988-10-26 | Mitsubishi Kasei Corp | カルボキシスチレン誘導体およびそれを有効成分とする薬剤 |
| DE3723913A1 (de) * | 1987-07-18 | 1989-02-23 | Shell Agrar Gmbh & Co Kg | Neue phosphoniumsalze, ihre herstellung und verwendung |
| EP0318085A3 (en) * | 1987-11-25 | 1990-03-14 | Merck Frosst Canada Inc. | Heterazole dialkanoic acids |
| ES2052825T3 (es) * | 1988-07-15 | 1994-07-16 | Hoffmann La Roche | Derivados de cicloalquiltiazol. |
| US5001140A (en) * | 1989-04-17 | 1991-03-19 | Hoffmann-La Roche Inc. | Cycloalkylthiazoles |
| JPH02169583A (ja) * | 1988-12-22 | 1990-06-29 | Mitsubishi Kasei Corp | ビニルチアゾール誘導体およびそれを有効成分とする薬剤 |
| AU654140B2 (en) * | 1990-07-31 | 1994-10-27 | Lilly Industries Limited | N-benzyl indoles, processes for their preparation or pharmaceutical compositions containing them |
-
1992
- 1992-07-02 US US07/907,987 patent/US5273986A/en not_active Expired - Fee Related
-
1993
- 1993-06-24 EP EP93110073A patent/EP0577003A1/en not_active Withdrawn
- 1993-06-25 IL IL106141A patent/IL106141A0/xx unknown
- 1993-06-25 ZA ZA934603A patent/ZA934603B/xx unknown
- 1993-06-25 NZ NZ247988A patent/NZ247988A/en unknown
- 1993-06-28 HU HU9301881A patent/HUT72747A/hu unknown
- 1993-06-28 CA CA002099295A patent/CA2099295A1/en not_active Abandoned
- 1993-06-28 AU AU41562/93A patent/AU667107B2/en not_active Expired - Fee Related
- 1993-06-29 JP JP5185437A patent/JPH0680654A/ja active Pending
- 1993-06-30 MX MX9303958A patent/MX9303958A/es unknown
- 1993-06-30 UY UY23609A patent/UY23609A1/es unknown
- 1993-07-01 FI FI933037A patent/FI933037A/fi not_active Application Discontinuation
- 1993-07-01 PL PL29954493A patent/PL299544A1/xx unknown
- 1993-07-01 CN CN93109528A patent/CN1087086A/zh active Pending
- 1993-07-01 NO NO932399A patent/NO932399L/no unknown
- 1993-07-01 KR KR1019930012260A patent/KR940005602A/ko not_active Application Discontinuation
- 1993-07-01 BR BR9302737A patent/BR9302737A/pt not_active Application Discontinuation
- 1993-07-01 CZ CZ931334A patent/CZ133493A3/cs unknown
- 1993-09-02 US US08/116,386 patent/US5399702A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CZ133493A3 (en) | 1994-01-19 |
| CA2099295A1 (en) | 1994-01-03 |
| HU9301881D0 (en) | 1993-09-28 |
| CN1087086A (zh) | 1994-05-25 |
| FI933037A (fi) | 1994-01-03 |
| US5273986A (en) | 1993-12-28 |
| FI933037A0 (fi) | 1993-07-01 |
| PL299544A1 (en) | 1994-02-21 |
| US5399702A (en) | 1995-03-21 |
| KR940005602A (ko) | 1994-03-21 |
| NZ247988A (en) | 1995-11-27 |
| UY23609A1 (es) | 1993-12-21 |
| MX9303958A (es) | 1994-04-29 |
| IL106141A0 (en) | 1993-10-20 |
| ZA934603B (en) | 1994-01-05 |
| EP0577003A1 (en) | 1994-01-05 |
| HUT72747A (en) | 1996-05-28 |
| NO932399D0 (no) | 1993-07-01 |
| AU667107B2 (en) | 1996-03-07 |
| NO932399L (no) | 1994-01-03 |
| AU4156293A (en) | 1994-01-06 |
| JPH0680654A (ja) | 1994-03-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9302737A (pt) | Derivados de tiazolivinilfenila,processo para a preparacao de um composto,medicamento,uso e processos para tratar ou prevenir asma bronquica | |
| BR1100850A (pt) | Composto, processo para a preparação de um composto, e, composição farmacêutica | |
| BR1100323A (pt) | Composto, uso de um composto, composição farmacêutica e processo para preparar um composto | |
| BR9609780A (pt) | Composto uso de um composto processo para o tratamento de condições composição farmacêutica processos para preparar uma composição farmacêutica e para preparar um composto | |
| BR9501770A (pt) | Uso de um composto,composto,formulação farmacêutica e processo para preparar um composto | |
| BR9404203A (pt) | Compostos, processo para a preparação dos mesmos, medicamento, uso dos ditos compostos e processo de tratamento ou prevenção de distúrbios nervosos centrais | |
| PT90994A (pt) | Processo para a preparacao de um sistema para a preparacao de composicoes para aplicacao topica | |
| BR8803901A (pt) | Processo para a preparacao de derivados de 1-nitro-2,2-diaminoetileno,composicao praguicida,aplicacao e processo para combater pragas | |
| BR9408148A (pt) | Processo para tratamento de arritmia composto e formulação farmacêutica | |
| BR9602705A (pt) | Composto composição farmacéutica processo para a preparação de um composto e uso | |
| BR9505107A (pt) | Composto composiçao farmacêutica processo para a preparaçao de um composto e seu uso | |
| BR9103036A (pt) | Composto,formulacao farmaceutica e processo para a preparacao do composto | |
| BR9607346A (pt) | Composto utilizaç o de um composto composiç o farmacéutica e processo para o tratamento de um mamifero e para e preparaç o de compostos | |
| BR9302389A (pt) | Composto,formulacao farmaceutica e processo para preparar o composto | |
| BR9602337A (pt) | Composto processo para sua preparação usos do mesmo processo para tratamento de arritmias e medicamento | |
| BR9602025A (pt) | Composto composição farmacêutica uso e processo para a preparação de um composto | |
| BR8706915A (pt) | Processo para a preparacao de derivados metoxibenzofenona,metoxibenzofenonas e composto | |
| BR9301273A (pt) | Composto,formulacao farmaceutica,processo para preparar um composto e composto obtido | |
| BR9406923A (pt) | Compostos derivados de (1-heteroazolil-1-heterociclil)alcano processo para preparar os mesmos formulaçao farmaceutica uso de compostos e processo para o tratamento de disturbios neuropsiquiatricos cronicos e agudos | |
| BR9301399A (pt) | Processo para a preparacao de um monoazocorante | |
| BR8703423A (pt) | Processo para a preparacao de dialquilmaleinimidas,composicoes herbicidas,processos para o combate de ervas daninhas e para a preparacao de composicoes | |
| BR9406924A (pt) | Composto processo para preparar o mesmo formulaçao farmaceutica e uso de um composto | |
| BR9505571A (pt) | Oligômero composto medicamento processo para a produção de um medicamento e uso | |
| BR9603164A (pt) | Compostos processo para a preparação dos mesmos processo para a produção de preparações farmacêuticas preparação farmacêutica medicamentos e uso de compostos | |
| BR8900301A (pt) | Processo para a preparacao de compostos,composicoes inseticidas,emprego e processo para o combate de acarideos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EE | Request for examination | ||
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal | ||
| FC | Decision: refusal | ||
| HIFC | Refusal cancelled |