BR9206293A - Tiazolidinadionas hipoglicêmicas e intermediários - Google Patents
Tiazolidinadionas hipoglicêmicas e intermediáriosInfo
- Publication number
- BR9206293A BR9206293A BR9206293A BR9206293A BR9206293A BR 9206293 A BR9206293 A BR 9206293A BR 9206293 A BR9206293 A BR 9206293A BR 9206293 A BR9206293 A BR 9206293A BR 9206293 A BR9206293 A BR 9206293A
- Authority
- BR
- Brazil
- Prior art keywords
- intermediates
- hypoglycemic thiazolidinediones
- thiazolidinediones
- hypoglycemic
- Prior art date
Links
- 229940123464 Thiazolidinedione Drugs 0.000 title 1
- 230000002218 hypoglycaemic effect Effects 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 150000001467 thiazolidinediones Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73377191A | 1991-07-22 | 1991-07-22 | |
| PCT/US1992/005436 WO1993002079A1 (en) | 1991-07-22 | 1992-07-01 | Hypoglycemic thiazolidinediones and intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9206293A true BR9206293A (pt) | 1994-11-08 |
Family
ID=24949048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9206293A BR9206293A (pt) | 1991-07-22 | 1992-07-01 | Tiazolidinadionas hipoglicêmicas e intermediários |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6329408B1 (Direct) |
| EP (1) | EP0641338A1 (Direct) |
| JP (1) | JPH08823B2 (Direct) |
| CN (1) | CN1030195C (Direct) |
| AU (1) | AU665775B2 (Direct) |
| BR (1) | BR9206293A (Direct) |
| CA (1) | CA2111447C (Direct) |
| CZ (1) | CZ282831B6 (Direct) |
| HU (1) | HUT69692A (Direct) |
| IE (1) | IE922357A1 (Direct) |
| IL (1) | IL102573A (Direct) |
| MX (1) | MX9204279A (Direct) |
| NO (1) | NO301226B1 (Direct) |
| NZ (1) | NZ243653A (Direct) |
| PT (1) | PT100711B (Direct) |
| RU (1) | RU2079497C1 (Direct) |
| TW (1) | TW222626B (Direct) |
| WO (1) | WO1993002079A1 (Direct) |
| ZA (1) | ZA925468B (Direct) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE173728T1 (de) * | 1991-07-22 | 1998-12-15 | Pfizer | Verfahren zur herstellung von (s)-4-(3-(5-methyl- 2-phenyl-4-oxazolyl)- 1-hydroxypropyl> brombenzol |
| GB9308487D0 (en) * | 1993-04-23 | 1993-06-09 | Smithkline Beecham Plc | Novel compounds |
| PL337510A1 (en) | 1997-06-18 | 2000-08-28 | Smithkline Beecham Plc | Treatment of diabetes by means of derivatives of thiazolydinone and sulphonylurea |
| AR023700A1 (es) | 1998-11-12 | 2002-09-04 | Smithkline Beecham Plc | Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina |
| HK1040910B (en) * | 1998-11-12 | 2009-06-26 | Smithkline Beecham Plc | Pharmaceutical composition for modified release of an insulin sensitiser and metformin |
| DE60035682T2 (de) * | 1999-04-28 | 2008-04-30 | Sanofi-Aventis Deutschland Gmbh | Di-aryl-säurederivate als ppar rezeptor liganden |
| TW200528436A (en) * | 1999-09-22 | 2005-09-01 | Bristol Myers Squibb Co | Substituted acid derivatives useful as antiodiabetic and antiobesity agents and method |
| DK1228067T3 (da) * | 1999-11-10 | 2004-12-06 | Takeda Chemical Industries Ltd | 5-leddede heterocykliske forbindelser med hypoglykæmisk og hypolipidæmisk virkning |
| MXPA02011609A (es) * | 2000-05-26 | 2003-03-27 | Nippon Shinyaku Co Ltd | Compuestos heterociclicos. |
| GB0014969D0 (en) | 2000-06-19 | 2000-08-09 | Smithkline Beecham Plc | Novel method of treatment |
| JP2003040877A (ja) * | 2001-07-24 | 2003-02-13 | Sumika Fine Chemicals Co Ltd | ５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法 |
| PL210408B1 (pl) * | 2002-06-03 | 2012-01-31 | Novartis Ag | Zastosowanie podstawionych cyjanopirolidyn do wytwarzania leku do modulowania hiperlipidemii |
| BR0312452A (pt) * | 2002-07-03 | 2005-04-19 | Hoffmann La Roche | Composto; processo para a preparação de um composto; composição farmacêutica; uso de um composto; e método para o tratamento e/ou profilaxia de doenças que são moduladas por agonistas de ppar(alfa) e/ou ppar(gama) |
| US8216609B2 (en) | 2002-08-05 | 2012-07-10 | Torrent Pharmaceuticals Limited | Modified release composition of highly soluble drugs |
| US8268352B2 (en) | 2002-08-05 | 2012-09-18 | Torrent Pharmaceuticals Limited | Modified release composition for highly soluble drugs |
| NZ546031A (en) * | 2003-09-22 | 2009-03-31 | Ono Pharmaceutical Co | Phenylacetic acid derivative, process for producing the same, and use |
| EP1586573B1 (en) * | 2004-04-01 | 2007-02-07 | Sanofi-Aventis Deutschland GmbH | Oxadiazolones, processes for their preparation and their use as pharmaceuticals |
| US20120094959A1 (en) | 2010-10-19 | 2012-04-19 | Bonnie Blazer-Yost | Treatment of cystic diseases |
| US10034868B2 (en) | 2014-11-04 | 2018-07-31 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the prevention and the treatment of rapidly progressive glomerulonephritis |
| CN109867765A (zh) * | 2019-02-28 | 2019-06-11 | 中山大学惠州研究院 | 一种长效缓释可降解防污聚氨酯及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5522636A (en) | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| US4367234A (en) | 1980-07-28 | 1983-01-04 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
| US4342771A (en) | 1981-01-02 | 1982-08-03 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
| US4617312A (en) | 1983-01-17 | 1986-10-14 | Pfizer Inc. | Aldose reductase inhibiting 5-(2-alkoxyphenyl) thiazolidinediones |
| CN1003445B (zh) | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物，其制备方法和用途 |
| US4703052A (en) | 1985-05-21 | 1987-10-27 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
| FI91869C (fi) * | 1987-03-18 | 1994-08-25 | Tanabe Seiyaku Co | Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi |
| GB8713861D0 (en) * | 1987-06-13 | 1987-07-15 | Beecham Group Plc | Compounds |
| WO1989008651A1 (en) * | 1988-03-08 | 1989-09-21 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| US5036079A (en) | 1989-12-07 | 1991-07-30 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| US5089514A (en) | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
-
1992
- 1992-06-30 TW TW081105174A patent/TW222626B/zh active
- 1992-07-01 CZ CS94124A patent/CZ282831B6/cs not_active IP Right Cessation
- 1992-07-01 AU AU22973/92A patent/AU665775B2/en not_active Ceased
- 1992-07-01 WO PCT/US1992/005436 patent/WO1993002079A1/en not_active Ceased
- 1992-07-01 HU HU9400181A patent/HUT69692A/hu unknown
- 1992-07-01 JP JP5502812A patent/JPH08823B2/ja not_active Expired - Fee Related
- 1992-07-01 CA CA002111447A patent/CA2111447C/en not_active Expired - Fee Related
- 1992-07-01 EP EP92915346A patent/EP0641338A1/en not_active Withdrawn
- 1992-07-01 RU RU94012853/04A patent/RU2079497C1/ru not_active IP Right Cessation
- 1992-07-01 BR BR9206293A patent/BR9206293A/pt not_active Application Discontinuation
- 1992-07-20 PT PT100711A patent/PT100711B/pt active IP Right Grant
- 1992-07-21 IL IL102573A patent/IL102573A/xx not_active IP Right Cessation
- 1992-07-21 NZ NZ243653A patent/NZ243653A/en unknown
- 1992-07-21 ZA ZA925468A patent/ZA925468B/xx unknown
- 1992-07-21 MX MX9204279A patent/MX9204279A/es not_active IP Right Cessation
- 1992-07-21 IE IE235792A patent/IE922357A1/en not_active Application Discontinuation
- 1992-07-21 CN CN92108662A patent/CN1030195C/zh not_active Expired - Fee Related
-
1994
- 1994-01-21 NO NO940225A patent/NO301226B1/no unknown
-
1995
- 1995-06-01 US US08/458,071 patent/US6329408B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HU9400181D0 (en) | 1994-05-30 |
| EP0641338A1 (en) | 1995-03-08 |
| NZ243653A (en) | 1995-02-24 |
| IL102573A0 (en) | 1993-01-14 |
| CZ12494A3 (en) | 1994-07-13 |
| MX9204279A (es) | 1994-03-31 |
| PT100711A (pt) | 1993-09-30 |
| ZA925468B (en) | 1994-01-21 |
| JPH07502487A (ja) | 1995-03-16 |
| IL102573A (en) | 1997-04-15 |
| AU665775B2 (en) | 1996-01-18 |
| RU2079497C1 (ru) | 1997-05-20 |
| CZ282831B6 (cs) | 1997-10-15 |
| CA2111447C (en) | 2002-08-13 |
| TW222626B (Direct) | 1994-04-21 |
| HUT69692A (en) | 1995-09-28 |
| AU2297392A (en) | 1993-02-23 |
| CN1068823A (zh) | 1993-02-10 |
| CN1030195C (zh) | 1995-11-01 |
| US6329408B1 (en) | 2001-12-11 |
| NO940225D0 (no) | 1994-01-21 |
| WO1993002079A1 (en) | 1993-02-04 |
| NO301226B1 (no) | 1997-09-29 |
| PT100711B (pt) | 1999-07-30 |
| JPH08823B2 (ja) | 1996-01-10 |
| CA2111447A1 (en) | 1993-02-04 |
| NO940225L (no) | 1994-01-21 |
| IE922357A1 (en) | 1993-01-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EE | Request for examination | ||
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal | ||
| FC | Decision: refusal |