BR9102418A - Proteinas homogenea e de fusao conjugado,processo para conversao de uma prorip em uma rip,isolado de adn,veiculo de expressao e celula hospedeira - Google Patents

Proteinas homogenea e de fusao conjugado,processo para conversao de uma prorip em uma rip,isolado de adn,veiculo de expressao e celula hospedeira

Info

Publication number
BR9102418A
BR9102418A BR919102418A BR9102418A BR9102418A BR 9102418 A BR9102418 A BR 9102418A BR 919102418 A BR919102418 A BR 919102418A BR 9102418 A BR9102418 A BR 9102418A BR 9102418 A BR9102418 A BR 9102418A
Authority
BR
Brazil
Prior art keywords
prorip
homogene
rip
dna
isolated
Prior art date
Application number
BR919102418A
Other languages
English (en)
Inventor
Terence A Waish
Timothy D Hey
Alice E R Morgan
Original Assignee
Dowelanco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dowelanco filed Critical Dowelanco
Publication of BR9102418A publication Critical patent/BR9102418A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
BR919102418A 1990-06-11 1991-06-11 Proteinas homogenea e de fusao conjugado,processo para conversao de uma prorip em uma rip,isolado de adn,veiculo de expressao e celula hospedeira BR9102418A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/535,636 US5248606A (en) 1990-06-11 1990-06-11 Dna encoding inactive precursor and active forms of maize ribosome inactivating protein

Publications (1)

Publication Number Publication Date
BR9102418A true BR9102418A (pt) 1992-01-14

Family

ID=24135102

Family Applications (1)

Application Number Title Priority Date Filing Date
BR919102418A BR9102418A (pt) 1990-06-11 1991-06-11 Proteinas homogenea e de fusao conjugado,processo para conversao de uma prorip em uma rip,isolado de adn,veiculo de expressao e celula hospedeira

Country Status (10)

Country Link
US (1) US5248606A (pt)
EP (1) EP0466222B1 (pt)
JP (1) JPH04279599A (pt)
CN (1) CN1062172A (pt)
AT (1) ATE184289T1 (pt)
AU (1) AU638133B2 (pt)
BR (1) BR9102418A (pt)
CA (1) CA2044201A1 (pt)
DE (1) DE69131589T2 (pt)
HU (1) HUT58800A (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672683A (en) * 1989-09-07 1997-09-30 Alkermes, Inc. Transferrin neuropharmaceutical agent fusion protein
US5635384A (en) * 1990-06-11 1997-06-03 Dowelanco Ribosome-inactivating proteins, inactive precursor forms thereof, a process for making and a method of using
DE4040954C2 (de) * 1990-12-20 2001-05-17 Max Planck Gesellschaft Verfahren zur Erzeugung von pathogen-resistenten Pflanzen
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
EP0633881B1 (en) * 1992-03-11 2003-10-29 Narhex Limited Amine derivatives of oxo- and hydroxy-substitued hydrocarbons
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
MXPA93002392A (es) 1992-03-11 2005-02-04 Narhex Ltd Derivados amino de hidrocarburos-oxo e hidroxi-substituidos.
GB9304905D0 (en) * 1992-03-16 1993-04-28 Zeneca Ltd Processes
US5916772A (en) * 1992-06-16 1999-06-29 Whittier Institute For Diabetes And Endocrinology Recombinant production of saporin-containing proteins
US5332808A (en) * 1992-09-08 1994-07-26 North Carolina State University DNA encoding a ribosome inactivating protein
KR970001565B1 (ko) * 1993-08-28 1997-02-11 장기하 섬자리공 항바이러스성 단백질(pip) 유전자 및 이를 발현하는 미생물
EG23907A (en) * 1994-08-01 2007-12-30 Delta & Pine Land Co Control of plant gene expression
JPH0856655A (ja) * 1994-08-16 1996-03-05 Frontier:Kk 細胞致死剤および細胞死抑制剤
EP0909322B1 (en) * 1996-04-30 2005-11-16 Twinstrand Therapeutics Inc. Antiviral ricin-like proteins
CA2288943C (en) 1997-04-30 2011-02-01 De Novo Enzyme Corporation Ricin-like toxin variants for treatment of cancer, viral or parasitic infections
WO2001025267A2 (en) 1999-10-04 2001-04-12 Twinstrand Therapeutics Inc. Improved ricin-like toxins for treatment of cancer
US7247715B2 (en) 1997-04-30 2007-07-24 Twinstrand Therapeutics Inc. Ricin-like toxin variants for treatment of cancer, viral or parasitic infections
EP0948347A4 (en) * 1997-07-16 2000-08-30 Sophie Chen ANTI-VIRALS AND ANTI-TUMOR ACTIVE SUBSTANCES
AU2401800A (en) * 1998-12-31 2000-07-31 Rutgers, The State University Virus-resistant transgenic plants expressing l3
US6531125B1 (en) 1999-03-02 2003-03-11 Twinstrand Therapeutics Inc. Antiviral ricin-like proteins
AU2006201828B2 (en) * 2000-10-14 2009-07-16 British American Tobacco (Investments) Limited Plant cell death system
GB0025225D0 (en) * 2000-10-14 2000-11-29 Cambridge Advanced Tech Plant cell death system
US7560424B2 (en) 2001-04-30 2009-07-14 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US7629309B2 (en) 2002-05-29 2009-12-08 Zystor Therapeutics, Inc. Targeted therapeutic proteins
WO2002101036A1 (fr) * 2001-05-11 2002-12-19 Kazunari Taira Methode de formation d'un complexe stable d'un transcrit d'adn codant un peptide arbitraire a l'aide d'un produit de traduction, construction d'acide nucleique utilisee dans cette methode, complexe obtenu par cette methode et criblage de proteine fonctionnelle et marn ou adn codant la proteine a l'aide de cette methode
US20030072761A1 (en) 2001-10-16 2003-04-17 Lebowitz Jonathan Methods and compositions for targeting proteins across the blood brain barrier
WO2005078077A2 (en) 2004-02-10 2005-08-25 Zystor Therapeutics, Inc. Acid alpha-glucosidase and fragments thereof
DK2279210T3 (en) 2008-05-07 2017-07-24 Biomarin Pharm Inc Lysosomal targeting peptides and uses thereof
ES2569514T3 (es) 2009-06-17 2016-05-11 Biomarin Pharmaceutical Inc. Formulaciones para enzimas lisosómicas
CN102234638B (zh) * 2010-04-27 2013-03-27 香港中文大学 修饰的玉米核糖体失活蛋白前体及其应用和蛋白纯化方法
CN110455903A (zh) * 2018-05-07 2019-11-15 天士力生物医药股份有限公司 一种注射用重组人尿激酶原杂质分析的梯度电泳检测方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3584486D1 (de) * 1984-02-08 1991-11-28 Cetus Corp Toxinkonjugate.
NZ218460A (en) * 1985-11-29 1989-07-27 Univ Melbourne Ricin-antibody conjugate
FR2601679B1 (fr) * 1986-07-15 1990-05-25 Sanofi Sa Immunotoxines, procede de preparation et compositions pharmaceutiques en contenant
DE3724323C2 (de) * 1986-07-29 1995-07-20 Erba Farmitalia Ein neuer Inhibitor für die Proteinsynthese
US4869903A (en) * 1987-05-29 1989-09-26 Genelabs Incorporated Method of selectively inhibiting HIV
GB8801877D0 (en) * 1988-01-28 1988-02-24 Erba Carlo Spa Nucleotide sequence encoding plant ribosome inactivating protein
IT1229216B (it) * 1989-03-31 1991-07-25 Italfarmaco Spa Proteine inibenti i ribosomi e loro derivati.
AU654563B2 (en) * 1991-07-24 1994-11-10 Imperial Chemical Industries Plc Proteins

Also Published As

Publication number Publication date
EP0466222A1 (en) 1992-01-15
DE69131589D1 (de) 1999-10-14
JPH04279599A (ja) 1992-10-05
EP0466222B1 (en) 1999-09-08
ATE184289T1 (de) 1999-09-15
AU7832991A (en) 1991-12-12
CA2044201A1 (en) 1991-12-12
AU638133B2 (en) 1993-06-17
HU911944D0 (en) 1991-12-30
DE69131589T2 (de) 2000-05-04
HUT58800A (en) 1992-03-30
CN1062172A (zh) 1992-06-24
US5248606A (en) 1993-09-28

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