BR9102418A - Proteinas homogenea e de fusao conjugado,processo para conversao de uma prorip em uma rip,isolado de adn,veiculo de expressao e celula hospedeira - Google Patents

Proteinas homogenea e de fusao conjugado,processo para conversao de uma prorip em uma rip,isolado de adn,veiculo de expressao e celula hospedeira

Info

Publication number
BR9102418A
BR9102418A BR919102418A BR9102418A BR9102418A BR 9102418 A BR9102418 A BR 9102418A BR 919102418 A BR919102418 A BR 919102418A BR 9102418 A BR9102418 A BR 9102418A BR 9102418 A BR9102418 A BR 9102418A
Authority
BR
Brazil
Prior art keywords
prorip
homogene
rip
dna
isolated
Prior art date
Application number
BR919102418A
Other languages
English (en)
Inventor
Terence A Waish
Timothy D Hey
Alice E R Morgan
Original Assignee
Dowelanco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dowelanco filed Critical Dowelanco
Publication of BR9102418A publication Critical patent/BR9102418A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR919102418A 1990-06-11 1991-06-11 Proteinas homogenea e de fusao conjugado,processo para conversao de uma prorip em uma rip,isolado de adn,veiculo de expressao e celula hospedeira BR9102418A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/535,636 US5248606A (en) 1990-06-11 1990-06-11 Dna encoding inactive precursor and active forms of maize ribosome inactivating protein

Publications (1)

Publication Number Publication Date
BR9102418A true BR9102418A (pt) 1992-01-14

Family

ID=24135102

Family Applications (1)

Application Number Title Priority Date Filing Date
BR919102418A BR9102418A (pt) 1990-06-11 1991-06-11 Proteinas homogenea e de fusao conjugado,processo para conversao de uma prorip em uma rip,isolado de adn,veiculo de expressao e celula hospedeira

Country Status (10)

Country Link
US (1) US5248606A (pt)
EP (1) EP0466222B1 (pt)
JP (1) JPH04279599A (pt)
CN (1) CN1062172A (pt)
AT (1) ATE184289T1 (pt)
AU (1) AU638133B2 (pt)
BR (1) BR9102418A (pt)
CA (1) CA2044201A1 (pt)
DE (1) DE69131589T2 (pt)
HU (1) HUT58800A (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672683A (en) * 1989-09-07 1997-09-30 Alkermes, Inc. Transferrin neuropharmaceutical agent fusion protein
US5635384A (en) * 1990-06-11 1997-06-03 Dowelanco Ribosome-inactivating proteins, inactive precursor forms thereof, a process for making and a method of using
DE4040954C2 (de) * 1990-12-20 2001-05-17 Max Planck Gesellschaft Verfahren zur Erzeugung von pathogen-resistenten Pflanzen
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
DE69333270T2 (de) 1992-03-11 2004-08-05 Narhex Ltd. Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
NZ249789A (en) * 1992-03-11 1997-07-27 Narhex Ltd Hydrazine, carbazate and 1,2-diazacyclic derivatives and pharmaceutical compositions
GB9304905D0 (en) * 1992-03-16 1993-04-28 Zeneca Ltd Processes
CA2138038A1 (en) * 1992-06-16 1993-12-23 Douglas A. Lappi Recombinant production of saporin-containing proteins
US5332808A (en) * 1992-09-08 1994-07-26 North Carolina State University DNA encoding a ribosome inactivating protein
KR970001565B1 (ko) * 1993-08-28 1997-02-11 장기하 섬자리공 항바이러스성 단백질(pip) 유전자 및 이를 발현하는 미생물
EG23907A (en) * 1994-08-01 2007-12-30 Delta & Pine Land Co Control of plant gene expression
JPH0856655A (ja) * 1994-08-16 1996-03-05 Frontier:Kk 細胞致死剤および細胞死抑制剤
DE69734656T2 (de) * 1996-04-30 2006-08-10 Twinstrand Therapeutics Inc., Burnaby Antivirale variante von ricin-proteinen
US7247715B2 (en) 1997-04-30 2007-07-24 Twinstrand Therapeutics Inc. Ricin-like toxin variants for treatment of cancer, viral or parasitic infections
JP4566290B2 (ja) 1997-04-30 2010-10-20 ツインストランド・ホールディングス・インコーポレイテッド 癌、ウイルスまたは寄生虫感染を治療するためのリシン様毒素変異体
WO2001025267A2 (en) 1999-10-04 2001-04-12 Twinstrand Therapeutics Inc. Improved ricin-like toxins for treatment of cancer
WO1999003492A1 (en) * 1997-07-16 1999-01-28 Sophie Chen Antiviral and antitumor agents
WO2000039291A1 (en) * 1998-12-31 2000-07-06 Rutgers, The State University Virus-resistant transgenic plants expressing l3
US6531125B1 (en) 1999-03-02 2003-03-11 Twinstrand Therapeutics Inc. Antiviral ricin-like proteins
GB0025225D0 (en) * 2000-10-14 2000-11-29 Cambridge Advanced Tech Plant cell death system
AU2006201828B2 (en) * 2000-10-14 2009-07-16 British American Tobacco (Investments) Limited Plant cell death system
US7560424B2 (en) 2001-04-30 2009-07-14 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US7629309B2 (en) 2002-05-29 2009-12-08 Zystor Therapeutics, Inc. Targeted therapeutic proteins
JP4106441B2 (ja) * 2001-05-11 2008-06-25 独立行政法人産業技術総合研究所 任意のポリペプチドをコードするＤＮＡの転写産物と翻訳産物との安定的な複合体を形成させる方法、該方法に用いる核酸構築物、該方法により形成される複合体、並びに該方法を利用した機能性タンパク質および該タンパク質をコードするｍＲＮＡまたはＤＮＡのスクリーニング
US20030072761A1 (en) 2001-10-16 2003-04-17 Lebowitz Jonathan Methods and compositions for targeting proteins across the blood brain barrier
US20050244400A1 (en) 2004-02-10 2005-11-03 Zystor Therapeutics, Inc. Acid alpha-glucosidase and fragments thereof
EP2279210B1 (en) 2008-05-07 2017-04-12 BioMarin Pharmaceutical Inc. Lysosomal targeting peptides and uses thereof
EP2475376B1 (en) 2009-06-17 2016-03-30 BioMarin Pharmaceutical Inc. Formulations for lysosomal enzymes
CN102234638B (zh) * 2010-04-27 2013-03-27 香港中文大学 修饰的玉米核糖体失活蛋白前体及其应用和蛋白纯化方法
US10347262B2 (en) 2017-10-18 2019-07-09 The Nielsen Company (Us), Llc Systems and methods to improve timestamp transition resolution
CN110455903A (zh) * 2018-05-07 2019-11-15 天士力生物医药股份有限公司 一种注射用重组人尿激酶原杂质分析的梯度电泳检测方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0170697B1 (en) * 1984-02-08 1991-10-23 Cetus Oncology Corporation Toxin conjugates
DE3688137D1 (de) * 1985-11-29 1993-04-29 Consolidated Pharmaceuticals L Ricin-antikoerper-konjugate.
FR2601679B1 (fr) * 1986-07-15 1990-05-25 Sanofi Sa Immunotoxines, procede de preparation et compositions pharmaceutiques en contenant
DE3724323C2 (de) * 1986-07-29 1995-07-20 Erba Farmitalia Ein neuer Inhibitor für die Proteinsynthese
US4869903A (en) * 1987-05-29 1989-09-26 Genelabs Incorporated Method of selectively inhibiting HIV
GB8801877D0 (en) * 1988-01-28 1988-02-24 Erba Carlo Spa Nucleotide sequence encoding plant ribosome inactivating protein
IT1229216B (it) * 1989-03-31 1991-07-25 Italfarmaco Spa Proteine inibenti i ribosomi e loro derivati.
AU654563B2 (en) * 1991-07-24 1994-11-10 Imperial Chemical Industries Plc Proteins

Also Published As

Publication number Publication date
DE69131589D1 (de) 1999-10-14
US5248606A (en) 1993-09-28
HUT58800A (en) 1992-03-30
DE69131589T2 (de) 2000-05-04
ATE184289T1 (de) 1999-09-15
AU7832991A (en) 1991-12-12
HU911944D0 (en) 1991-12-30
EP0466222B1 (en) 1999-09-08
JPH04279599A (ja) 1992-10-05
CN1062172A (zh) 1992-06-24
AU638133B2 (en) 1993-06-17
CA2044201A1 (en) 1991-12-12
EP0466222A1 (en) 1992-01-15

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