BR112023026141A2 - Métodos para produzir uma população de células enriquecida em células nk, para produzir células nk derivadas de células-tronco pluripotentes induzidas, para tratar um sujeito em necessidade de terapia de células e para produzir uma população de células compreendendo células progenitoras hematopoiéticas cd34+, e, populações de células nk e de células não classificadas - Google Patents

Métodos para produzir uma população de células enriquecida em células nk, para produzir células nk derivadas de células-tronco pluripotentes induzidas, para tratar um sujeito em necessidade de terapia de células e para produzir uma população de células compreendendo células progenitoras hematopoiéticas cd34+, e, populações de células nk e de células não classificadas

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Publication number
BR112023026141A2
BR112023026141A2 BR112023026141A BR112023026141A BR112023026141A2 BR 112023026141 A2 BR112023026141 A2 BR 112023026141A2 BR 112023026141 A BR112023026141 A BR 112023026141A BR 112023026141 A BR112023026141 A BR 112023026141A BR 112023026141 A2 BR112023026141 A2 BR 112023026141A2
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Brazil
Prior art keywords
cells
producing
cell population
induced pluripotent
populations
Prior art date
Application number
BR112023026141A
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English (en)
Portuguese (pt)
Inventor
Hui-Hsin Chang
Jianxin Hu
Lan Cao
Xi Shi
Yu Qian
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Takeda Pharmaceuticals Co
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Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of BR112023026141A2 publication Critical patent/BR112023026141A2/pt

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/421—Immunoglobulin superfamily
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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BR112023026141A 2021-06-15 2022-06-14 Métodos para produzir uma população de células enriquecida em células nk, para produzir células nk derivadas de células-tronco pluripotentes induzidas, para tratar um sujeito em necessidade de terapia de células e para produzir uma população de células compreendendo células progenitoras hematopoiéticas cd34+, e, populações de células nk e de células não classificadas BR112023026141A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163210683P 2021-06-15 2021-06-15
PCT/IB2022/055504 WO2022264033A1 (en) 2021-06-15 2022-06-14 Method for producing natural killer cells from pluripotent stem cells

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BR112023026141A2 true BR112023026141A2 (pt) 2024-03-05

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US (1) US20240108656A1 (https=)
EP (1) EP4355861A1 (https=)
JP (1) JP2024523332A (https=)
KR (1) KR20240021878A (https=)
CN (1) CN117813374A (https=)
AR (1) AR126145A1 (https=)
AU (1) AU2022292988A1 (https=)
BR (1) BR112023026141A2 (https=)
CA (1) CA3222770A1 (https=)
CO (1) CO2023018654A2 (https=)
MX (1) MX2023014979A (https=)
TW (1) TW202317755A (https=)
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TW202600815A (zh) * 2024-03-05 2026-01-01 美商Ｒ Ｐ 先靈爾科技公司 將多能幹細胞分化成自然殺手細胞之方法

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