AR120475A1 - Producción de células precursoras hematopoyéticas - Google Patents
Producción de células precursoras hematopoyéticasInfo
- Publication number
- AR120475A1 AR120475A1 ARP200103167A ARP200103167A AR120475A1 AR 120475 A1 AR120475 A1 AR 120475A1 AR P200103167 A ARP200103167 A AR P200103167A AR P200103167 A ARP200103167 A AR P200103167A AR 120475 A1 AR120475 A1 AR 120475A1
- Authority
- AR
- Argentina
- Prior art keywords
- precursor cells
- hematopoietic precursor
- production
- hematopoietic
- runx1c
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/02—Atmosphere, e.g. low oxygen conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/99—Serum-free medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/41—Hedgehog proteins; Cyclopamine (inhibitor)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente proporciona métodos mejorados para la generación de células precursoras hematopoyéticas a partir de una célula madre pluripotente y células precursoras hematopoyéticas generadas a partir de las mismas. Las células precursoras hematopoyéticas expresan CXCR4 o runx1c y son capaces de migrar a, y/o injertarse en, la médula ósea.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962935353P | 2019-11-14 | 2019-11-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR120475A1 true AR120475A1 (es) | 2022-02-16 |
Family
ID=73790249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP200103167A AR120475A1 (es) | 2019-11-14 | 2020-11-16 | Producción de células precursoras hematopoyéticas |
Country Status (9)
Country | Link |
---|---|
US (1) | US20220411755A1 (es) |
EP (1) | EP4058564A1 (es) |
JP (1) | JP2023501520A (es) |
AR (1) | AR120475A1 (es) |
AU (1) | AU2020381537A1 (es) |
CA (1) | CA3161465A1 (es) |
MX (1) | MX2022005892A (es) |
TW (1) | TW202132563A (es) |
WO (1) | WO2021097346A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4271798A1 (en) | 2020-12-30 | 2023-11-08 | CRISPR Therapeutics AG | Compositions and methods for differentiating stem cells into nk cells |
CN116445408B (zh) * | 2023-05-22 | 2024-02-02 | 呈诺再生医学科技(北京)有限公司 | LSD1抑制剂在促进iPSC向HSC分化和HSC干性维持中的应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2197915B (en) | 1986-11-19 | 1990-11-14 | Rolls Royce Plc | Improvements in or relating to fluid bearings |
JP5943533B2 (ja) | 2000-05-17 | 2016-07-06 | アステリアス バイオセラピューティクス インコーポレイテッド | 神経前駆細胞の集団 |
CA3003152A1 (en) * | 2015-11-04 | 2017-05-11 | Fate Therapeutics, Inc. | Methods and compositions for inducing hematopoietic cell differentiation |
WO2017192708A1 (en) * | 2016-05-03 | 2017-11-09 | The Children's Medical Center Corporation | Hematopoietic stem and progenitor cells derived from hemogenic endothelial cells |
-
2020
- 2020-11-13 JP JP2022527112A patent/JP2023501520A/ja active Pending
- 2020-11-13 AU AU2020381537A patent/AU2020381537A1/en active Pending
- 2020-11-13 US US17/776,622 patent/US20220411755A1/en active Pending
- 2020-11-13 EP EP20821507.9A patent/EP4058564A1/en active Pending
- 2020-11-13 MX MX2022005892A patent/MX2022005892A/es unknown
- 2020-11-13 WO PCT/US2020/060582 patent/WO2021097346A1/en unknown
- 2020-11-13 CA CA3161465A patent/CA3161465A1/en active Pending
- 2020-11-16 AR ARP200103167A patent/AR120475A1/es unknown
- 2020-11-16 TW TW109139975A patent/TW202132563A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
CA3161465A1 (en) | 2021-05-20 |
MX2022005892A (es) | 2022-06-14 |
AU2020381537A1 (en) | 2022-06-09 |
WO2021097346A1 (en) | 2021-05-20 |
US20220411755A1 (en) | 2022-12-29 |
JP2023501520A (ja) | 2023-01-18 |
EP4058564A1 (en) | 2022-09-21 |
TW202132563A (zh) | 2021-09-01 |
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