BR112023023149A2 - Precursores de marcação diméricos conjugados via um trislinker e radiotraçadores derivados dos mesmos - Google Patents
Precursores de marcação diméricos conjugados via um trislinker e radiotraçadores derivados dos mesmosInfo
- Publication number
- BR112023023149A2 BR112023023149A2 BR112023023149A BR112023023149A BR112023023149A2 BR 112023023149 A2 BR112023023149 A2 BR 112023023149A2 BR 112023023149 A BR112023023149 A BR 112023023149A BR 112023023149 A BR112023023149 A BR 112023023149A BR 112023023149 A2 BR112023023149 A2 BR 112023023149A2
- Authority
- BR
- Brazil
- Prior art keywords
- trislinker
- radiotracers
- derived
- dimmer
- conjugated via
- Prior art date
Links
- 239000002243 precursor Substances 0.000 title abstract 3
- 238000002372 labelling Methods 0.000 abstract 3
- 125000006850 spacer group Chemical group 0.000 abstract 3
- 238000010668 complexation reaction Methods 0.000 abstract 1
- 239000000700 radioactive tracer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Treatment And Processing Of Natural Fur Or Leather (AREA)
- Paints Or Removers (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102021114711.5A DE102021114711B4 (de) | 2021-06-08 | 2021-06-08 | Trislinker-konjugierte dimere Markierungsvorläufer und daraus abgeleitete Radiotracer |
| PCT/EP2022/065440 WO2022258637A1 (de) | 2021-06-08 | 2022-06-07 | Trislinker-konjugierte dimere markierungsvorläufer und daraus abgeleitete radiotracer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023023149A2 true BR112023023149A2 (pt) | 2024-01-23 |
Family
ID=82258261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023023149A BR112023023149A2 (pt) | 2021-06-08 | 2022-06-07 | Precursores de marcação diméricos conjugados via um trislinker e radiotraçadores derivados dos mesmos |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4351663A1 (zh) |
| KR (1) | KR20240019301A (zh) |
| CN (1) | CN117642190A (zh) |
| AU (1) | AU2022288744A1 (zh) |
| BR (1) | BR112023023149A2 (zh) |
| CA (1) | CA3222226A1 (zh) |
| DE (1) | DE102021114711B4 (zh) |
| WO (1) | WO2022258637A1 (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023133645A1 (en) * | 2022-01-14 | 2023-07-20 | Provincial Health Services Authority | Radiolabeled compounds for imaging of fibroblast activation protein (fap) and treatment of fap-related disorders |
| WO2023222558A1 (en) | 2022-05-14 | 2023-11-23 | Zounek Alexis Nikolai | Precursor and theranostic radiotracer with improved tumor retention |
| DE102022116009A1 (de) | 2022-06-28 | 2023-12-28 | Positron Precision GmbH | Fibroblasten-Aktivierungsprotein adressierender Präkursor und Radiotracer |
| CN115947775B (zh) * | 2023-03-13 | 2023-06-09 | 北京先通国际医药科技股份有限公司 | 一种制备化合物（i）的方法和化合物（i）及其用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT4095130T (lt) | 2013-10-18 | 2024-04-25 | Novartis Ag | Žymėti prostatos specifinio membranos antigeno (psma) inhibitoriai, jų naudojimas kaip vizualizavimo medžiagų ir farmacinių medžiagų prostatos vėžiui gydyti |
| DE102018126558A1 (de) * | 2018-10-24 | 2020-04-30 | Helmholtz-Zentrum Dresden - Rossendorf E.V. | Markierungsvorläufer mit Quadratsäure-Kopplung |
| US11167048B2 (en) * | 2018-12-14 | 2021-11-09 | The Curators Of The University Of Missouri | Dual targeting ligand for cancer diagnosis and treatment |
| JP2022548749A (ja) * | 2019-09-20 | 2022-11-21 | ザ ユニバーシティー オブ メルボルン | 画像化及び治療用組成物 |
| DE102021101216A1 (de) * | 2021-01-21 | 2022-07-21 | Johannes Gutenberg-Universität Mainz, Körperschaft des öffentlichen Rechts | Markierungsvorläufer und Radiotracer zur nuklearmedizinischen Diagnose und Therapie von Prostatakrebs induzierten Knochenmetastasen |
| CN113880810B (zh) * | 2021-09-24 | 2023-02-28 | 厦门大学 | 一种核素标记的配合物及其制备方法和应用 |
-
2021
- 2021-06-08 DE DE102021114711.5A patent/DE102021114711B4/de active Active
-
2022
- 2022-06-07 EP EP22734235.9A patent/EP4351663A1/de active Pending
- 2022-06-07 KR KR1020247000764A patent/KR20240019301A/ko unknown
- 2022-06-07 BR BR112023023149A patent/BR112023023149A2/pt unknown
- 2022-06-07 CN CN202280040063.2A patent/CN117642190A/zh active Pending
- 2022-06-07 CA CA3222226A patent/CA3222226A1/en active Pending
- 2022-06-07 AU AU2022288744A patent/AU2022288744A1/en active Pending
- 2022-06-07 WO PCT/EP2022/065440 patent/WO2022258637A1/de active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| DE102021114711B4 (de) | 2023-11-02 |
| DE102021114711A1 (de) | 2022-12-08 |
| AU2022288744A9 (en) | 2023-12-21 |
| EP4351663A1 (de) | 2024-04-17 |
| CA3222226A1 (en) | 2022-12-15 |
| CN117642190A (zh) | 2024-03-01 |
| KR20240019301A (ko) | 2024-02-14 |
| AU2022288744A1 (en) | 2023-12-14 |
| WO2022258637A1 (de) | 2022-12-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112023023149A2 (pt) | Precursores de marcação diméricos conjugados via um trislinker e radiotraçadores derivados dos mesmos | |
| BR122019003178B1 (pt) | método de controle de pestes | |
| TR199801641T2 (xx) | Tropan t�revleri bunlar�n haz�rlanmas� ve kullan�m� | |
| CY1109955T1 (el) | Δισκιο τροποποιημενης απελευθερωσης υδροχλωριουχου bupropion | |
| BR112022006001A2 (pt) | Imunoconjugado, composto de 8-amido-2-aminobenzazepina-ligante, composto de 5-amino-pirazoloazepina-ligante, composto de aminoquinolina-ligante, uso de um imunoconjugado e métodos para tratar câncer e para preparar um imunoconjugado | |
| BRPI0510059A (pt) | inibidores da transcriptase reversa não-nucleosìdica | |
| BR0213207A (pt) | remodelagem e glicoconjugação de peptìdeos | |
| BRPI0508125A (pt) | formulação de alcalóide, método para melhorar a eficácia de um alcalóide, uso do produto da reação de um ou mais alcalóides com um mais derivados de fosfato de um ou mais agentes de transferência de elétrons, junto com excipientes e composição farmacêutica | |
| RS51235B (sr) | Derivati n-(aminoheteroaril)-1h-indol-2-karboksamida, njihovo dobijanje i njihova terapeutska primena | |
| BRPI0720972B8 (pt) | compostos análogos de ciclopamina e composições farmacêuticas compreendendo os referidos compostos | |
| BRPI0715579A2 (pt) | "composto, composição farmacêutica e uso de um composto" | |
| BRPI0618589B8 (pt) | composto de oxazol, composição farmacêutica compreendendo o referido composto, processos de fabricação e usos dos mesmos | |
| UY30030A1 (es) | Derivados sustituidos de la 8-piracin-2-il-1,2,4,4a-tetrahidro-2´h, 6h-espiro (1,4-oxacin(4,3-a)quinolin-5,5´-pirimidin)-2´, 4´, 6´ (1´h, 3´h)-tiona, composiciones y aplicaciones | |
| BR0211227A (pt) | Composto, composição farmacêutica e seus usos | |
| BR0009314A (pt) | Uso de um composto como fungicida, compostos fungicidas, composição fungicida e método de combate a fungos | |
| CY1113003T1 (el) | Ευσταθη παρασκευασματα laquinimod | |
| CY1105194T1 (el) | Φωσφονικα παραγωγα γλυκοπεπτιδιων | |
| BR0214485A (pt) | 3-cianoquinolinas como inibidores de egf-r e her2 quinases | |
| BR0307687A (pt) | Composições cosméticas tópicas | |
| BR112012012141A2 (pt) | composição de controle de peste | |
| BRPI0507903A (pt) | derivados de quinazolina e composição farmacêutica compreendendo os mesmos | |
| BRPI0508997A (pt) | microcamada com siloxanas | |
| CY1114838T1 (el) | Φαρμακευτικες τοπικες συνθεσεις | |
| BRPI0408353A (pt) | composto, composição farmacêutica, métodos para o tratamento de neoplasias suscetìveis e para o tratamento de infecções virais, e, uso de um composto | |
| BR0208274A (pt) | Composições antitumorais contendo derivados de taxano |