BR112022021020A2 - Método de fabricação de um produto de terapia celular, métodos de tratamento do paciente com o produto de terapia celular de expansão e fabricado, e, método de fabricação de um produto de terapia celular - Google Patents

Método de fabricação de um produto de terapia celular, métodos de tratamento do paciente com o produto de terapia celular de expansão e fabricado, e, método de fabricação de um produto de terapia celular

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Publication number
BR112022021020A2
BR112022021020A2 BR112022021020A BR112022021020A BR112022021020A2 BR 112022021020 A2 BR112022021020 A2 BR 112022021020A2 BR 112022021020 A BR112022021020 A BR 112022021020A BR 112022021020 A BR112022021020 A BR 112022021020A BR 112022021020 A2 BR112022021020 A2 BR 112022021020A2
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Brazil
Prior art keywords
therapy product
cell therapy
patient
expansion
manufacturing
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BR112022021020A
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English (en)
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Brooks Anne
Macrides Steve
Lanzi Kristin
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Iovance Biotherapeutics Inc
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Application filed by Iovance Biotherapeutics Inc filed Critical Iovance Biotherapeutics Inc
Publication of BR112022021020A2 publication Critical patent/BR112022021020A2/pt

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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
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Abstract

MÉTODO DE FABRICAÇÃO DE UM PRODUTO DE TERAPIA CELULAR, MÉTODOS DE TRATAMENTO DO PACIENTE COM O PRODUTO DE TERAPIA CELULAR DE EXPANSÃO E FABRICADO, E, MÉTODO DE FABRICAÇÃO DE UM PRODUTO DE TERAPIA CELULAR. Um método para coordenar a fabricação de um produto de terapia celular expandido para um paciente pode incluir receber uma solicitação de pedido celular para expandir o produto de terapia celular para o paciente; gerar um identificador específico do paciente ou identificador de pedido celular associado à solicitação de pedido celular; e iniciar um processo para expandir o produto de terapia celular de pelo menos um pouco de um tumor sólido obtido do paciente. Se os parâmetros de aceitação para o produto de terapia celular de expansão não atenderem a certos critérios de aceitação em um segundo ponto de tempo subsequente a um primeiro ponto de tempo no processo de expansão, determina-se se a repetição da expansão do produto de terapia celular usando a técnica de expansão celular é possível a partir do primeiro ponto de tempo com base nos parâmetros de aceitação no segundo ponto de tempo. Se tal reexecução da expansão for possível, os eventos de tratamento do paciente que usam o produto de terapia celular expandido são reprogramados.
BR112022021020A 2020-04-22 2021-04-22 Método de fabricação de um produto de terapia celular, métodos de tratamento do paciente com o produto de terapia celular de expansão e fabricado, e, método de fabricação de um produto de terapia celular BR112022021020A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202063013942P 2020-04-22 2020-04-22
US202163155711P 2021-03-02 2021-03-02
US202163159806P 2021-03-11 2021-03-11
PCT/US2021/028709 WO2021216920A1 (en) 2020-04-22 2021-04-22 Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy

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BR112022021020A2 true BR112022021020A2 (pt) 2023-02-14

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BR112022021020A BR112022021020A2 (pt) 2020-04-22 2021-04-22 Método de fabricação de um produto de terapia celular, métodos de tratamento do paciente com o produto de terapia celular de expansão e fabricado, e, método de fabricação de um produto de terapia celular

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US (5) US20210335467A1 (pt)
EP (1) EP4139440A1 (pt)
JP (1) JP2023524639A (pt)
KR (1) KR20230037069A (pt)
CN (1) CN115997008A (pt)
AU (1) AU2021258257A1 (pt)
BR (1) BR112022021020A2 (pt)
CA (1) CA3176356A1 (pt)
IL (1) IL297442A (pt)
MX (1) MX2022013065A (pt)
TW (1) TW202206592A (pt)
WO (1) WO2021216920A1 (pt)

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