DK3532607T3 - Restimulation af kryokonserverede, tumorinfiltrerende lymfocytter - Google Patents

Restimulation af kryokonserverede, tumorinfiltrerende lymfocytter Download PDF

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Publication number
DK3532607T3
DK3532607T3 DK17798045.5T DK17798045T DK3532607T3 DK 3532607 T3 DK3532607 T3 DK 3532607T3 DK 17798045 T DK17798045 T DK 17798045T DK 3532607 T3 DK3532607 T3 DK 3532607T3
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Denmark
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restimulation
cryopreserved
lymphocytes
tumor
filtering
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DK17798045.5T
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Ian Frank
Michael T Lotze
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Iovance Biotherapeutics Inc
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
    • A61K2239/57—Skin; melanoma
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    • C07K2319/00—Fusion polypeptide
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/04—Immunosuppressors, e.g. cyclosporin, tacrolimus
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2302—Interleukin-2 (IL-2)
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    • C12N2502/00—Coculture with; Conditioned medium produced by
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    • C12N2502/99—Coculture with; Conditioned medium produced by genetically modified cells

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DK17798045.5T 2016-10-26 2017-10-26 Restimulation af kryokonserverede, tumorinfiltrerende lymfocytter DK3532607T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662413387P 2016-10-26 2016-10-26
US201662413283P 2016-10-26 2016-10-26
US201662415452P 2016-10-31 2016-10-31
PCT/US2017/058610 WO2018081473A1 (en) 2016-10-26 2017-10-26 Restimulation of cryopreserved tumor infiltrating lymphocytes

Publications (1)

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DK3532607T3 true DK3532607T3 (da) 2024-04-02

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US (22) US11026974B2 (da)
EP (2) EP3532607B1 (da)
JP (2) JP2019532652A (da)
KR (1) KR20190066073A (da)
CN (1) CN110099998A (da)
AU (1) AU2017347851B2 (da)
BR (1) BR112019008305A2 (da)
CA (1) CA3041678A1 (da)
DK (1) DK3532607T3 (da)
ES (1) ES2977118T3 (da)
FI (1) FI3532607T3 (da)
HR (1) HRP20240436T1 (da)
HU (1) HUE066460T2 (da)
IL (1) IL266209B1 (da)
LT (1) LT3532607T (da)
MD (1) MD3532607T2 (da)
MX (2) MX2019004707A (da)
PL (1) PL3532607T3 (da)
PT (1) PT3532607T (da)
RS (1) RS65448B1 (da)
SG (1) SG11201903331QA (da)
SI (1) SI3532607T1 (da)
WO (1) WO2018081473A1 (da)

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