DK3500682T3 - Fremstilling af lukket, lineært dna - Google Patents
Fremstilling af lukket, lineært dna Download PDFInfo
- Publication number
- DK3500682T3 DK3500682T3 DK17757824.2T DK17757824T DK3500682T3 DK 3500682 T3 DK3500682 T3 DK 3500682T3 DK 17757824 T DK17757824 T DK 17757824T DK 3500682 T3 DK3500682 T3 DK 3500682T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- closed
- linear dna
- dna
- linear
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/10—Nucleotidyl transfering
- C12Q2521/113—Telomerase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/151—Modifications characterised by repeat or repeated sequences, e.g. VNTR, microsatellite, concatemer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/30—Oligonucleotides characterised by their secondary structure
- C12Q2525/301—Hairpin oligonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/30—Oligonucleotides characterised by their secondary structure
- C12Q2525/307—Circular oligonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/119—Strand displacement amplification [SDA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/125—Rolling circle
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1613994.1A GB201613994D0 (en) | 2016-08-16 | 2016-08-16 | Production of closed linear DNA |
| GBGB1621954.5A GB201621954D0 (en) | 2016-12-22 | 2016-12-22 | Closed linear DNA production |
| PCT/GB2017/052413 WO2018033730A1 (en) | 2016-08-16 | 2017-08-16 | Closed linear dna production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3500682T3 true DK3500682T3 (da) | 2020-08-24 |
Family
ID=59702752
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17757824.2T DK3500682T3 (da) | 2016-08-16 | 2017-08-16 | Fremstilling af lukket, lineært dna |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11505821B2 (da) |
| EP (2) | EP3763823A1 (da) |
| CN (2) | CN109844134B (da) |
| DK (1) | DK3500682T3 (da) |
| ES (1) | ES2813324T3 (da) |
| LT (1) | LT3500682T (da) |
| WO (1) | WO2018033730A1 (da) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10077459B2 (en) | 2016-05-04 | 2018-09-18 | General Electric Company | Cell-free protein expression using rolling circle amplification product |
| US10590452B2 (en) * | 2017-12-20 | 2020-03-17 | University Of Seoul Industry Cooperation Foundation | DNA-Mn hybrid particles and method of manufacturing the same |
| GB201905651D0 (en) * | 2019-04-24 | 2019-06-05 | Lightbio Ltd | Nucleic acid constructs and methods for their manufacture |
| EP3792367A1 (en) | 2019-09-11 | 2021-03-17 | Universität Bielefeld | Method for the production of raav and method for the in vitro generation of genetically engineered, linear, single-stranded nucleic acid fragments containing itr sequences flanking a gene of interest |
| CA3131183A1 (en) * | 2019-10-25 | 2021-04-29 | Illumina Cambridge Limited | Methods for generating, and sequencing from, asymmetric adaptors on the ends of polynucleotide templates comprising hairpin loops |
| WO2021123062A1 (en) * | 2019-12-20 | 2021-06-24 | Keygene N.V. | Ngs library preparation using covalently closed nucleic acid molecule ends |
| CN115023503A (zh) * | 2020-01-31 | 2022-09-06 | 泰瑞斯疗法公司 | 生产闭合线性dna的方法 |
| CA3181680A1 (en) | 2020-06-12 | 2021-12-16 | University Of Rochester | Encoding and expression of ace-trnas |
| CN112080475B (zh) * | 2020-07-30 | 2022-02-11 | 扬州大学 | 一种副溶血性弧菌噬菌体及其在检测副溶血性弧菌大流行株活细胞含量中的应用 |
| GB202014751D0 (en) * | 2020-09-18 | 2020-11-04 | Lightbio Ltd | Targeting vector |
| CN113201583B (zh) * | 2021-04-29 | 2022-02-08 | 国科宁波生命与健康产业研究院 | 恒温条件下合成核酸的方法及试剂盒和应用 |
| GB202108176D0 (en) | 2021-06-08 | 2021-07-21 | Touchlight Ip Ltd | Vector |
| CA3222751A1 (en) | 2021-06-08 | 2022-12-15 | Touchlight IP Limited | Lentiviral vector |
| AU2022299552A1 (en) | 2021-06-25 | 2024-01-04 | Oxford Biomedica (Us) Llc | Adeno-associated virus packaging systems |
| WO2023114901A2 (en) | 2021-12-15 | 2023-06-22 | Oxford Biomedica Solutions Llc | Methods and compositions for the production of adeno-associated virus |
| WO2023122523A1 (en) | 2021-12-20 | 2023-06-29 | Zoetis Services Llc | Compositions and methods for expressing antigens on cell membrane |
| WO2023122525A1 (en) | 2021-12-20 | 2023-06-29 | Zoetis Services Llc | Compositions and methods for prevention of piscine myocarditis |
| WO2023122526A1 (en) | 2021-12-20 | 2023-06-29 | Zoetis Services Llc | Use of interferon as an adjuvant in vaccines |
| WO2023154788A2 (en) * | 2022-02-10 | 2023-08-17 | Code Biotherapeutics, Inc. | Enhanced dna dendrimers and methods of use thereof |
| WO2023220729A2 (en) * | 2022-05-13 | 2023-11-16 | Flagship Pioneering Innovations Vii, Llc | Double stranded dna compositions and related methods |
| EP4293101A1 (en) | 2022-06-14 | 2023-12-20 | Asklepios Biopharmaceutical, Inc. | Reactor with temperature control and method of using the same |
| WO2024059486A1 (en) | 2022-09-12 | 2024-03-21 | Zoetis Services Llc | Method of administration of aquaculture vaccines |
| CN116606834A (zh) * | 2023-04-10 | 2023-08-18 | 天津中合基因科技有限公司 | 多种具有切割连接活性的原端酶及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE503829T1 (de) * | 2002-04-09 | 2011-04-15 | Kyowa Hakko Kirin Co Ltd | Zelle mit erniedrigter oder deletierter aktivität eines am gdp-fucosetransport beteiligten proteins |
| EP1951870B1 (de) * | 2005-11-25 | 2013-04-24 | Mologen AG | Dna-konstrukte zur spezifischen hemmung der genexpression durch rna-interferenz |
| CA2836368C (en) * | 2006-02-13 | 2020-04-07 | Monsanto Technology Llc | Method for managing crop pest resistance |
| BRPI0909212A2 (pt) * | 2008-03-28 | 2015-08-18 | Pacific Biosciences California | Composições e método para sequeciamento de ácido nucléico |
| GB0901593D0 (en) | 2009-01-30 | 2009-03-11 | Touchlight Genetics Ltd | Production of closed linear DNA |
| GB201013153D0 (en) * | 2010-08-04 | 2010-09-22 | Touchlight Genetics Ltd | Primer for production of closed linear DNA |
| AU2012304537B2 (en) * | 2011-09-06 | 2015-08-20 | Gen-Probe Incorporated | Closed nucleic acid structures |
| US9404147B2 (en) * | 2011-12-19 | 2016-08-02 | Gen-Probe Incorporated | Closed nucleic acid structures |
| EP2692870A1 (en) * | 2012-08-03 | 2014-02-05 | Alacris Theranostics GmbH | Method for nucleic acid amplification |
| GB201415789D0 (en) * | 2014-09-05 | 2014-10-22 | Touchlight Genetics Ltd | Synthesis of DNA |
-
2017
- 2017-08-16 WO PCT/GB2017/052413 patent/WO2018033730A1/en unknown
- 2017-08-16 US US16/325,621 patent/US11505821B2/en active Active
- 2017-08-16 CN CN201780063788.2A patent/CN109844134B/zh active Active
- 2017-08-16 CN CN202310457342.5A patent/CN116732145A/zh active Pending
- 2017-08-16 LT LTEP17757824.2T patent/LT3500682T/lt unknown
- 2017-08-16 EP EP20184316.6A patent/EP3763823A1/en active Pending
- 2017-08-16 EP EP17757824.2A patent/EP3500682B1/en active Active
- 2017-08-16 DK DK17757824.2T patent/DK3500682T3/da active
- 2017-08-16 ES ES17757824T patent/ES2813324T3/es active Active
-
2022
- 2022-10-06 US US17/938,553 patent/US20230272461A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3763823A1 (en) | 2021-01-13 |
| CN109844134A (zh) | 2019-06-04 |
| ES2813324T8 (es) | 2021-03-31 |
| US11505821B2 (en) | 2022-11-22 |
| WO2018033730A1 (en) | 2018-02-22 |
| ES2813324T3 (es) | 2021-03-23 |
| LT3500682T (lt) | 2020-10-26 |
| EP3500682A1 (en) | 2019-06-26 |
| CN116732145A (zh) | 2023-09-12 |
| US20190185924A1 (en) | 2019-06-20 |
| CN109844134B (zh) | 2023-05-05 |
| US20230272461A1 (en) | 2023-08-31 |
| EP3500682B1 (en) | 2020-07-08 |
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