BR112022008113A2 - Formas sólidas de um modulador de receptor s1p - Google Patents

Formas sólidas de um modulador de receptor s1p

Info

Publication number
BR112022008113A2
BR112022008113A2 BR112022008113A BR112022008113A BR112022008113A2 BR 112022008113 A2 BR112022008113 A2 BR 112022008113A2 BR 112022008113 A BR112022008113 A BR 112022008113A BR 112022008113 A BR112022008113 A BR 112022008113A BR 112022008113 A2 BR112022008113 A2 BR 112022008113A2
Authority
BR
Brazil
Prior art keywords
solid forms
receiver modulator
modulator
receiver
diseases
Prior art date
Application number
BR112022008113A
Other languages
English (en)
Inventor
De Lombaert Stéphane
Rosario Mollo Sarno Ana
A Christie Michael
L Ciolkowski Edward
DEL RIO GANCEDO Susana
Stephen Harris Joseph
Kristina Mapp Lucy
Bogumil Pitak Mateusz
L Childs Scott
Original Assignee
Escape Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Escape Bio Inc filed Critical Escape Bio Inc
Publication of BR112022008113A2 publication Critical patent/BR112022008113A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Details Of Television Scanning (AREA)
  • Liquid Crystal Substances (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

FORMAS SÓLIDAS DE UM MODULADOR DE RECEPTOR S1P. O presente pedido se refere a formas sólidas de um modulador do receptor S1P da fórmula a seguir, que são úteis no tratamento contra doenças ou contra distúrbios associados à atividade de S1P, incluindo distúrbios do SNC. Composto 1.
BR112022008113A 2019-10-31 2020-10-30 Formas sólidas de um modulador de receptor s1p BR112022008113A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962928412P 2019-10-31 2019-10-31
PCT/US2020/058269 WO2021087299A1 (en) 2019-10-31 2020-10-30 Solid forms of an s1p-receptor modulator

Publications (1)

Publication Number Publication Date
BR112022008113A2 true BR112022008113A2 (pt) 2022-07-19

Family

ID=73544378

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022008113A BR112022008113A2 (pt) 2019-10-31 2020-10-30 Formas sólidas de um modulador de receptor s1p

Country Status (12)

Country Link
US (2) US11535632B2 (pt)
EP (1) EP4051683A1 (pt)
JP (1) JP2022553802A (pt)
KR (1) KR20220123634A (pt)
CN (1) CN114728982A (pt)
AU (1) AU2020373047A1 (pt)
BR (1) BR112022008113A2 (pt)
CA (1) CA3159378A1 (pt)
IL (1) IL292547A (pt)
MX (1) MX2022005084A (pt)
TW (1) TW202132311A (pt)
WO (1) WO2021087299A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201643169A (zh) 2010-07-09 2016-12-16 艾伯維股份有限公司 作為s1p調節劑的螺-哌啶衍生物
CN117007818B (zh) * 2023-08-04 2024-04-09 徐州医科大学科技园发展有限公司 S1pr1作为靶点在开发或制备用于预防慢性疼痛相关记忆损伤疾病的药物中的应用

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Also Published As

Publication number Publication date
JP2022553802A (ja) 2022-12-26
EP4051683A1 (en) 2022-09-07
AU2020373047A1 (en) 2022-05-19
US20210139502A1 (en) 2021-05-13
CN114728982A (zh) 2022-07-08
IL292547A (en) 2022-06-01
KR20220123634A (ko) 2022-09-08
TW202132311A (zh) 2021-09-01
MX2022005084A (es) 2022-05-26
US11535632B2 (en) 2022-12-27
WO2021087299A1 (en) 2021-05-06
CA3159378A1 (en) 2021-05-06
US20230339967A1 (en) 2023-10-26

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