BR112022002834A2 - Métodos para a administração de certos inibidores de vmat2 a pacientes com insuficiência renal severa - Google Patents
Métodos para a administração de certos inibidores de vmat2 a pacientes com insuficiência renal severaInfo
- Publication number
- BR112022002834A2 BR112022002834A2 BR112022002834A BR112022002834A BR112022002834A2 BR 112022002834 A2 BR112022002834 A2 BR 112022002834A2 BR 112022002834 A BR112022002834 A BR 112022002834A BR 112022002834 A BR112022002834 A BR 112022002834A BR 112022002834 A2 BR112022002834 A2 BR 112022002834A2
- Authority
- BR
- Brazil
- Prior art keywords
- patients
- administration
- methods
- kidney failure
- severe kidney
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
MÉTODOS PARA A ADMINISTRAÇÃO DE CERTOS INIBIDORES DE VMAT2 A PACIENTES COM INSUFICIÊNCIA RENAL SEVERA. A presente invenção refere-se a um método de administração de um inibidor do transportador-2 de monoamina vesicular (VMAT2) a um indivíduo em necessidade do mesmo, em que o indivíduo apresenta insuficiência renal severa.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962890697P | 2019-08-23 | 2019-08-23 | |
US202063028754P | 2020-05-22 | 2020-05-22 | |
PCT/US2020/047392 WO2021041208A1 (en) | 2019-08-23 | 2020-08-21 | Methods for the administration of certain vmat2 inhibitors to patients with severe renal impairment |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022002834A2 true BR112022002834A2 (pt) | 2022-06-28 |
Family
ID=72292706
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022002834A BR112022002834A2 (pt) | 2019-08-23 | 2020-08-21 | Métodos para a administração de certos inibidores de vmat2 a pacientes com insuficiência renal severa |
Country Status (13)
Country | Link |
---|---|
US (1) | US10940141B1 (pt) |
EP (1) | EP4017494A1 (pt) |
JP (1) | JP2022544711A (pt) |
KR (1) | KR20220051239A (pt) |
CN (1) | CN114679906A (pt) |
AU (1) | AU2020336017A1 (pt) |
BR (1) | BR112022002834A2 (pt) |
CA (1) | CA3149033A1 (pt) |
IL (1) | IL290686A (pt) |
JO (1) | JOP20220040A1 (pt) |
MX (1) | MX2022000559A (pt) |
TW (1) | TW202114675A (pt) |
WO (1) | WO2021041208A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20200066662A (ko) | 2017-01-27 | 2020-06-10 | 뉴로크린 바이오사이언시즈 인코퍼레이티드 | 특정 vmat2 억제제의 투여 방법 |
MX2020002841A (es) | 2017-09-21 | 2020-07-22 | Neurocrine Biosciences Inc | Formulacion de valbenazina de alta dosis y composiciones, metodos y kits relacionados con la misma. |
EA202090932A1 (ru) | 2017-10-10 | 2021-05-20 | Нейрокрин Байосайенсиз, Инк | Способы введения некоторых vmat2-ингибиторов |
CA3104693A1 (en) | 2018-08-15 | 2020-02-20 | Neurocrine Biosciences, Inc. | Methods for the administration of certain vmat2 inhibitors |
JP2024514873A (ja) * | 2021-04-15 | 2024-04-03 | ニューロクライン バイオサイエンシーズ,インコーポレイテッド | デューテトラベナジンおよびcyp2d6阻害剤の併用投与のための方法 |
BR112023021151A2 (pt) * | 2021-04-15 | 2023-12-12 | Neurocrine Biosciences Inc | Métodos para administração de certos inibidores de vmat2 |
EP4362942A1 (en) | 2021-06-30 | 2024-05-08 | Neurocrine Biosciences, Inc. | Valbenazine for use in the treatment of dyskinesia due to cerebral palsy |
KR20240027780A (ko) | 2021-06-30 | 2024-03-04 | 뉴로크린 바이오사이언시즈 인코퍼레이티드 | 조현병의 부가적 치료에 사용하기 위한 발베나진 |
WO2023172849A1 (en) | 2022-03-07 | 2023-09-14 | Neurocrine Biosciences, Inc. | Valbenazine, a vmat2 inhibitor, as a free base a tosylate or ditosylate salt, for use in the treatment of chorea associated with huntington's disease |
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MA52896A (fr) | 2018-06-14 | 2021-04-21 | Neurocrine Biosciences Inc | Composés inhibiteurs de vmat2, compositions et méthodes associées |
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-
2020
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- 2020-08-21 JO JOP/2022/0040A patent/JOP20220040A1/ar unknown
- 2020-08-21 BR BR112022002834A patent/BR112022002834A2/pt unknown
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WO2021041208A1 (en) | 2021-03-04 |
MX2022000559A (es) | 2022-02-10 |
IL290686A (en) | 2022-04-01 |
AU2020336017A1 (en) | 2022-04-07 |
EP4017494A1 (en) | 2022-06-29 |
TW202114675A (zh) | 2021-04-16 |
JOP20220040A1 (ar) | 2023-01-30 |
US20210052558A1 (en) | 2021-02-25 |
CN114679906A (zh) | 2022-06-28 |
US10940141B1 (en) | 2021-03-09 |
CA3149033A1 (en) | 2021-03-04 |
KR20220051239A (ko) | 2022-04-26 |
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