BR112021016818A2 - Método para síntese in vivo de 4-hidroximetilfurfural e derivados do mesmo - Google Patents

Método para síntese in vivo de 4-hidroximetilfurfural e derivados do mesmo

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Publication number
BR112021016818A2
BR112021016818A2 BR112021016818A BR112021016818A BR112021016818A2 BR 112021016818 A2 BR112021016818 A2 BR 112021016818A2 BR 112021016818 A BR112021016818 A BR 112021016818A BR 112021016818 A BR112021016818 A BR 112021016818A BR 112021016818 A2 BR112021016818 A2 BR 112021016818A2
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Brazil
Prior art keywords
formylfuran
carboxylate
furandimethanol
dicarbaldehyde
fdca
Prior art date
Application number
BR112021016818A
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English (en)
Inventor
Estrada Gouvea Iuri
Moises Raduan Alexandrino Paulo
Leite Queiroz Veronica
Original Assignee
Braskem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Braskem Sa filed Critical Braskem Sa
Publication of BR112021016818A2 publication Critical patent/BR112021016818A2/pt

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    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
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    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01005—Aldehyde dehydrogenase [NAD(P)+] (1.2.1.5)
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    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)

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  • Chemical & Material Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
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  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Furan Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

método para síntese in vivo de 4-hidroximetilfurfural e derivados do mesmo. a presente divulgação fornece micro-organismos recombinantes e métodos para a produção de 4-hmf, 2,4-furandimetanol, furan-2,4-dicarbaldeído, ácido 4-(hidroximetil)furoico, 2-formilfuran-4-carboxilato, 4-formilfuran-2-carboxilato e/ou 2,4-fdca a partir de uma fonte de carbono. o método prevê micro-organismos manipulados que expressam moléculas de ácido nucleico endógenas e/ou exógenas que catalisam a conversão de uma fonte de carbono em 4-hmf, 2,4-furandimetanol, furan-2,4-dicarbaldeído, ácido 4-(hidroximetil)furoico, 2-formilfuran-4-carboxilato, 4-formilfuran-2-carboxilato e/ou 2,4-fdca. a divulgação fornece ainda métodos de produção de polímeros derivados de 4-hmf, 2,4-furandimetanol, furan-2,4-dicarbaldeído, ácido 4-(hidroximetil)furoico, 2-formilfuran-4-carboxilato, 4-formilfuran-2-carboxilato e/ou 2,4-fdca.
BR112021016818A 2019-03-01 2020-03-02 Método para síntese in vivo de 4-hidroximetilfurfural e derivados do mesmo BR112021016818A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962812904P 2019-03-01 2019-03-01
PCT/BR2020/050064 WO2020176958A1 (en) 2019-03-01 2020-03-02 Method for the in vivo synthesis of 4-hydroxymethylfurfural and derivatives thereof

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BR112021016818A2 true BR112021016818A2 (pt) 2021-11-16

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US (5) US11339414B2 (pt)
EP (1) EP3921435A1 (pt)
JP (1) JP2022523540A (pt)
KR (1) KR20210136044A (pt)
CN (1) CN113748211A (pt)
BR (1) BR112021016818A2 (pt)
CA (1) CA3132051A1 (pt)
MX (1) MX2021010457A (pt)
WO (1) WO2020176958A1 (pt)

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US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
JP2023527820A (ja) * 2020-05-29 2023-06-30 ブラスケン・エス．エー． フランジカルボキシル酸ジエステルの２，４－異性体に基づく可塑剤の生産及び使用
US11692210B2 (en) 2020-09-01 2023-07-04 Braskem S.A. Anaerobic fermentative production of furandicarboxylic acid
WO2022047559A1 (en) 2020-09-01 2022-03-10 Braskem S.A. Anaerobic fermentative production of furandimethanol and enzymatic production of furandicarboxylic acid
CN117043225A (zh) 2021-01-29 2023-11-10 布拉斯科公司 具有提高的结晶控制的2,4-fdca的共聚酯
US20230002363A1 (en) 2021-06-16 2023-01-05 Braskem S.A. Furanic diglycidyl ethers and esters and use thereof
CN113913448B (zh) * 2021-07-23 2023-10-20 中国人民解放军军事科学院军事医学研究院 一种提高甲基营养菌吡咯喹啉醌产量的方法及应用
GB202217116D0 (en) * 2022-11-16 2022-12-28 Univ Nottingham biosynthesis of plastics precursors

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JP2022523540A (ja) 2022-04-25
CN113748211A (zh) 2021-12-03
CA3132051A1 (en) 2020-09-10
US12006523B2 (en) 2024-06-11
KR20210136044A (ko) 2021-11-16
US11566270B2 (en) 2023-01-31
US20220298535A1 (en) 2022-09-22
EP3921435A1 (en) 2021-12-15
US20210238639A1 (en) 2021-08-05
WO2020176958A1 (en) 2020-09-10
US20200277639A1 (en) 2020-09-03
US20220090153A1 (en) 2022-03-24
MX2021010457A (es) 2021-12-10
US11339414B2 (en) 2022-05-24
US11566269B2 (en) 2023-01-31
US20210222217A1 (en) 2021-07-22

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