MX2021010457A - Método para la síntesis in vivo del 4-hidroximetilfurfural y sus derivados. - Google Patents

Método para la síntesis in vivo del 4-hidroximetilfurfural y sus derivados.

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Publication number
MX2021010457A
MX2021010457A MX2021010457A MX2021010457A MX2021010457A MX 2021010457 A MX2021010457 A MX 2021010457A MX 2021010457 A MX2021010457 A MX 2021010457A MX 2021010457 A MX2021010457 A MX 2021010457A MX 2021010457 A MX2021010457 A MX 2021010457A
Authority
MX
Mexico
Prior art keywords
formylfuran
carboxylate
furandimethanol
dicarbaldehyde
fdca
Prior art date
Application number
MX2021010457A
Other languages
English (en)
Inventor
Alexandrino Paulo Moises Raduan
Gouvea Iuri Estrada
Queiroz Veronica Leite
Original Assignee
Braskem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Braskem Sa filed Critical Braskem Sa
Publication of MX2021010457A publication Critical patent/MX2021010457A/es

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    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
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    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01003—Aldehyde dehydrogenase (NAD+) (1.2.1.3)
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    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01004—Aldehyde dehydrogenase (NADP+) (1.2.1.4)
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    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01005—Aldehyde dehydrogenase [NAD(P)+] (1.2.1.5)
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    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)

Abstract

La presente descripción proporciona microorganismos recombinantes y métodos para la producción de 4 HMF, 2,4-furandimetanol, furan-2,4-dicarbaldehído, ácido 4-(hidroximetil)furoico, 2-formilfuran-4-carboxilato, 4-formilfuran-2-carboxilato y/o 2,4-FDCA a partir de una fuente de carbono. El método proporciona microorganismos modificados que expresan moléculas de ácido nucleico endógenas y/o exógenas que catalizan la conversión de una fuente de carbono en 4-HMF, 2,4-furandimetanol, furan-2,4-dicarbaldehído, ácido 4-(hidroximetil)furoico, 2-formilfuran-4-carboxilato, 4-formilfuran-2-carboxilato y/o 2,4-FDCA. La descripción proporciona además métodos para producir polímeros derivados de 4-HMF, 2,4-furandimetanol, furan-2,4-dicarbaldehído, ácido 4-(hidroximetil)furoico, 2-formilfuran-4-carboxilato, 4-formilfuran-2 carboxilato 10 y/o 2,4-FDCA.
MX2021010457A 2019-03-01 2020-03-02 Método para la síntesis in vivo del 4-hidroximetilfurfural y sus derivados. MX2021010457A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962812904P 2019-03-01 2019-03-01
PCT/BR2020/050064 WO2020176958A1 (en) 2019-03-01 2020-03-02 Method for the in vivo synthesis of 4-hydroxymethylfurfural and derivatives thereof

Publications (1)

Publication Number Publication Date
MX2021010457A true MX2021010457A (es) 2021-12-10

Family

ID=70189623

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021010457A MX2021010457A (es) 2019-03-01 2020-03-02 Método para la síntesis in vivo del 4-hidroximetilfurfural y sus derivados.

Country Status (9)

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US (5) US11339414B2 (es)
EP (1) EP3921435A1 (es)
JP (1) JP2022523540A (es)
KR (1) KR20210136044A (es)
CN (1) CN113748211A (es)
BR (1) BR112021016818A2 (es)
CA (1) CA3132051A1 (es)
MX (1) MX2021010457A (es)
WO (1) WO2020176958A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
MX2022014991A (es) * 2020-05-29 2023-04-19 Braskem Sa Produccion y uso de plastificadores basados en 2,4-isomero de diesteres de acido furandicarboxilico.
WO2022047559A1 (en) 2020-09-01 2022-03-10 Braskem S.A. Anaerobic fermentative production of furandimethanol and enzymatic production of furandicarboxylic acid
US11692210B2 (en) 2020-09-01 2023-07-04 Braskem S.A. Anaerobic fermentative production of furandicarboxylic acid
EP4284855A1 (en) 2021-01-29 2023-12-06 Braskem, S.A. Copolyesters of 2,4-fdca with increased crystallization control
US20230002363A1 (en) 2021-06-16 2023-01-05 Braskem S.A. Furanic diglycidyl ethers and esters and use thereof
CN113913448B (zh) * 2021-07-23 2023-10-20 中国人民解放军军事科学院军事医学研究院 一种提高甲基营养菌吡咯喹啉醌产量的方法及应用

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US6740506B2 (en) 1995-12-07 2004-05-25 Diversa Corporation End selection in directed evolution
US6033861A (en) 1997-11-19 2000-03-07 Incyte Genetics, Inc. Methods for obtaining nucleic acid containing a mutation
US8460726B2 (en) 2006-12-18 2013-06-11 Advanced Bionutrition Corporation Dry food product containing live probiotic
EP2495239B1 (en) 2009-07-09 2016-11-16 University of Science and Technology of China Method for preparing 4-hydroxymethylfurfural
NL2006359C2 (en) * 2011-03-08 2012-04-24 Bird Engineering B V Genetically modified cell and process for use of said cell.
EP4234696A3 (en) 2012-12-12 2023-09-06 The Broad Institute Inc. Crispr-cas component systems, methods and compositions for sequence manipulation
US9937207B2 (en) 2013-03-21 2018-04-10 Sangamo Therapeutics, Inc. Targeted disruption of T cell receptor genes using talens
NL2011027C2 (en) * 2013-06-24 2014-12-29 Univ Delft Tech Process for the preparation of 2,5-furandicarboxylic acid.
DK3259349T3 (da) * 2015-02-17 2020-08-10 Purac Biochem Bv Dehydrogenase-katalyseret fremstilling af FDCA
EP3378931A1 (en) * 2017-03-21 2018-09-26 Purac Biochem B.V. Fdca-decarboxylating monooxygenase-deficient host cells for producing fdca

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US20210222217A1 (en) 2021-07-22
CA3132051A1 (en) 2020-09-10
BR112021016818A2 (pt) 2021-11-16
US11566269B2 (en) 2023-01-31
US20210238639A1 (en) 2021-08-05
US20220298535A1 (en) 2022-09-22
US11566270B2 (en) 2023-01-31
US20200277639A1 (en) 2020-09-03
US20220090153A1 (en) 2022-03-24
EP3921435A1 (en) 2021-12-15
US11339414B2 (en) 2022-05-24
WO2020176958A1 (en) 2020-09-10
KR20210136044A (ko) 2021-11-16
CN113748211A (zh) 2021-12-03
JP2022523540A (ja) 2022-04-25

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