BR112019015000A2 - uso de pridopidina para o tratamento da síndrome do x frágil - Google Patents
uso de pridopidina para o tratamento da síndrome do x frágil Download PDFInfo
- Publication number
- BR112019015000A2 BR112019015000A2 BR112019015000-5A BR112019015000A BR112019015000A2 BR 112019015000 A2 BR112019015000 A2 BR 112019015000A2 BR 112019015000 A BR112019015000 A BR 112019015000A BR 112019015000 A2 BR112019015000 A2 BR 112019015000A2
- Authority
- BR
- Brazil
- Prior art keywords
- individual
- pridopidine
- fact
- sxf
- amount
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762448595P | 2017-01-20 | 2017-01-20 | |
| US62/448,595 | 2017-01-20 | ||
| PCT/US2018/014169 WO2018136600A1 (en) | 2017-01-20 | 2018-01-18 | Use of pridopidine for the treatment of fragile x syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112019015000A2 true BR112019015000A2 (pt) | 2020-04-07 |
Family
ID=62908348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112019015000-5A BR112019015000A2 (pt) | 2017-01-20 | 2018-01-18 | uso de pridopidina para o tratamento da síndrome do x frágil |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11234973B2 (https=) |
| EP (1) | EP3570940B1 (https=) |
| JP (1) | JP7114604B2 (https=) |
| CN (1) | CN110505902B (https=) |
| AU (1) | AU2018210145B2 (https=) |
| BR (1) | BR112019015000A2 (https=) |
| CA (1) | CA3050700C (https=) |
| DK (1) | DK3570940T3 (https=) |
| ES (1) | ES2972205T3 (https=) |
| HU (1) | HUE068300T2 (https=) |
| IL (1) | IL268125B2 (https=) |
| PL (1) | PL3570940T3 (https=) |
| WO (1) | WO2018136600A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013536825A (ja) | 2010-09-03 | 2013-09-26 | イバックス・インターナショナル・ゲーエムベーハー | ドパミン作動性安定化剤として有用なプリドピジンの重水素化類似体 |
| US11090297B2 (en) | 2013-06-21 | 2021-08-17 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating huntington's disease |
| CA3035099C (en) | 2016-08-24 | 2023-01-17 | Prilenia Therapeutics Development Ltd. | Use of pridopidine for treating dystonias |
| EP4516356A3 (en) | 2016-08-24 | 2025-05-14 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating functional decline |
| US12102627B2 (en) | 2016-09-16 | 2024-10-01 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating rett syndrome |
| US12036213B2 (en) | 2017-09-08 | 2024-07-16 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating drug induced dyskinesias |
| JP2020533296A (ja) | 2017-09-08 | 2020-11-19 | プリレニア ニューロセラピューティクス リミテッド | 薬物誘発性ジスキネジアを治療するためのプリドピジン |
| CN113395964A (zh) | 2019-02-04 | 2021-09-14 | 普瑞尼亚神经治疗有限公司 | 用于帕金森氏病和与帕金森症相关的其它疾病的低剂量普利多匹定 |
| WO2021141426A1 (ko) * | 2020-01-08 | 2021-07-15 | 건국대학교 글로컬산학협력단 | 리수리드 화합물을 유효성분으로 포함하는 취약 x 증후군 또는 관련 발달 장애 치료용 조성물 |
| CN116472043A (zh) * | 2020-10-20 | 2023-07-21 | 普瑞尼亚神经治疗有限公司 | 普利多匹定和类似物用于治疗焦虑和抑郁的用途 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6472736A (en) | 1987-09-14 | 1989-03-17 | Toshiba Corp | Mri apparatus |
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| SE9904724D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| SE0401465D0 (sv) | 2004-06-08 | 2004-06-08 | Carlsson A Research Ab | New substituted piperdines as modulators of dopamine neurotransmission |
| EP1807394A1 (en) | 2004-10-13 | 2007-07-18 | Neurosearch Sweden AB | Process for the synthesis of 4-(3-sulfonylphenyl)-piperidines |
| CA2584831C (en) | 2004-10-13 | 2013-09-17 | Neurosearch Sweden Ab | Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-n-propyl-piperidine |
| EP1961742A1 (en) | 2007-02-22 | 2008-08-27 | Novartis AG | compounds of formula (I) as serine protease inhibitors |
| CN101711236B (zh) | 2007-04-12 | 2012-10-31 | Nsab神经研究瑞典公司分公司 | 表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物 |
| TW200848063A (en) * | 2007-04-23 | 2008-12-16 | Combinatorx Inc | Methods and compositions for the treatment of neurodegenerative disorders |
| WO2008155357A2 (en) | 2007-06-18 | 2008-12-24 | A. Carlsson Research Ab | Use of dopamine stabilizers |
| US20110206782A1 (en) | 2010-02-24 | 2011-08-25 | Auspex Pharmaceuticals, Inc. | Piperidine modulators of dopamine receptor |
| JP2013532233A (ja) | 2010-07-02 | 2013-08-15 | アクティエボラゲット・エスコーエッフ | 機械構成要素、および表面硬化方法 |
| JP2013536825A (ja) | 2010-09-03 | 2013-09-26 | イバックス・インターナショナル・ゲーエムベーハー | ドパミン作動性安定化剤として有用なプリドピジンの重水素化類似体 |
| US9708366B2 (en) | 2011-01-27 | 2017-07-18 | Neuren Pharmaceuticals Ltd. | Treatment of fragile X syndrome using glycyl-L-2-methylprolyl-L-glutamate |
| BR112014005389A8 (pt) | 2011-09-07 | 2018-04-03 | Ivax Int Gmbh | Sal cloridrato de 4- (3-metanossulfonil-fenil) -1- propil-piperidina em uma forma cristalina, composição farmacêutica compreendendo o mesmo e usos do dito sal |
| TWI579272B (zh) | 2011-12-08 | 2017-04-21 | 梯瓦製藥國際有限責任公司 | 普多比啶（ｐｒｉｄｏｐｉｄｉｎｅ）之氫溴酸鹽 |
| AU2013243461A1 (en) | 2012-04-04 | 2014-11-06 | Teva Pharmaceuticals International Gmbh | Pharmaceutical compositions for combination therapy |
| MX2015003608A (es) | 2012-09-27 | 2015-06-05 | Teva Pharma | Combinacion de laquinimod y pridopidina para tratar trastornos neurodegenerativos. |
| US20150216850A1 (en) * | 2012-09-27 | 2015-08-06 | Michael Hayden | Combination of rasagiline and pridopidine for treating neurodegenerative disorders, in particular huntington's disease |
| HK1221646A1 (zh) | 2013-06-21 | 2017-06-09 | Teva Pharmaceuticals International Gmbh | 高剂量普利多匹定用於治疗亨廷顿舞蹈症的用途 |
| MX377576B (es) | 2014-01-22 | 2025-03-04 | Prilenia Neurotherapeutics Ltd | Formulaciones de pridopidina de liberación modificada. |
| TW201613859A (en) | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| MX2017008136A (es) | 2014-12-22 | 2018-03-06 | Teva Pharmaceuticals Int Gmbh | Sal de l-tartrato de pridopidina. |
| WO2016138135A1 (en) | 2015-02-25 | 2016-09-01 | Teva Pharmaceuticals International Gmbh | Sigma-1 receptor modulators for treating huntington's disease |
| JP6887952B2 (ja) * | 2015-02-25 | 2021-06-16 | プリレニア ニューロセラピューティクス リミテッド | 認知機能を改善するため、およびアルツハイマー病を治療するためのプリドピジンの使用 |
| AR105434A1 (es) | 2015-07-22 | 2017-10-04 | Teva Pharmaceuticals Int Gmbh | Proceso para preparar pridopidina |
| EP3324967A4 (en) | 2015-07-22 | 2019-03-20 | Prilenia Therapeutics Development Ltd. | PRIDOPIDINE-BASED FORMULATIONS AND USE OF THE SAME |
| CN109952100A (zh) | 2016-09-15 | 2019-06-28 | 普瑞尼亚医疗发展有限公司 | 普利多匹定用于治疗焦虑和抑郁的用途 |
| CN121243170A (zh) | 2019-06-12 | 2026-01-02 | 普瑞尼亚神经治疗有限公司 | 用于治疗亨廷顿病及其症状的包含普利多匹定及其类似物的组合物 |
-
2018
- 2018-01-18 CA CA3050700A patent/CA3050700C/en active Active
- 2018-01-18 WO PCT/US2018/014169 patent/WO2018136600A1/en not_active Ceased
- 2018-01-18 IL IL268125A patent/IL268125B2/en unknown
- 2018-01-18 HU HUE18741607A patent/HUE068300T2/hu unknown
- 2018-01-18 ES ES18741607T patent/ES2972205T3/es active Active
- 2018-01-18 DK DK18741607.8T patent/DK3570940T3/da active
- 2018-01-18 EP EP18741607.8A patent/EP3570940B1/en active Active
- 2018-01-18 CN CN201880007913.2A patent/CN110505902B/zh active Active
- 2018-01-18 AU AU2018210145A patent/AU2018210145B2/en active Active
- 2018-01-18 PL PL18741607.8T patent/PL3570940T3/pl unknown
- 2018-01-18 JP JP2019539958A patent/JP7114604B2/ja active Active
- 2018-01-18 BR BR112019015000-5A patent/BR112019015000A2/pt not_active Application Discontinuation
-
2019
- 2019-07-17 US US16/514,167 patent/US11234973B2/en active Active
-
2022
- 2022-01-31 US US17/588,403 patent/US12551474B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018210145B2 (en) | 2023-06-29 |
| IL268125B2 (en) | 2023-04-01 |
| CN110505902A (zh) | 2019-11-26 |
| DK3570940T3 (da) | 2024-02-19 |
| CA3050700A1 (en) | 2018-07-26 |
| EP3570940B1 (en) | 2023-12-13 |
| ES2972205T3 (es) | 2024-06-11 |
| IL268125A (en) | 2019-09-26 |
| AU2018210145A1 (en) | 2019-08-29 |
| WO2018136600A1 (en) | 2018-07-26 |
| US20190336488A1 (en) | 2019-11-07 |
| EP3570940A4 (en) | 2020-10-28 |
| US20220202798A1 (en) | 2022-06-30 |
| PL3570940T3 (pl) | 2024-06-17 |
| EP3570940A1 (en) | 2019-11-27 |
| US12551474B2 (en) | 2026-02-17 |
| JP2020514313A (ja) | 2020-05-21 |
| CN110505902B (zh) | 2022-11-11 |
| IL268125B (en) | 2022-12-01 |
| US11234973B2 (en) | 2022-02-01 |
| JP7114604B2 (ja) | 2022-08-08 |
| HUE068300T2 (hu) | 2024-12-28 |
| CA3050700C (en) | 2023-10-03 |
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Legal Events
| Date | Code | Title | Description |
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| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICA??O DE DEVOLU??O DO PEDIDO EM FUN??O DA REVOGA??O DO ART. 229-C DA LEI N? 9.279, DE 1996, POR FOR?A DA LEI N? 14.195, DE 2021 |
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| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |