CN110505902B - 普利多匹定用于治疗脆性x综合征的应用 - Google Patents

普利多匹定用于治疗脆性x综合征的应用 Download PDF

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Publication number
CN110505902B
CN110505902B CN201880007913.2A CN201880007913A CN110505902B CN 110505902 B CN110505902 B CN 110505902B CN 201880007913 A CN201880007913 A CN 201880007913A CN 110505902 B CN110505902 B CN 110505902B
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pridopidine
subject
fxs
acid
vigabatrin
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Chinese (zh)
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CN110505902A (zh
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迈克尔·海登
马哈茂德·阿卜杜勒侯赛因·普拉迪
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Prenia Neurotherapy Co ltd
Agency for Science Technology and Research Singapore
National University of Singapore
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Prenia Neurotherapy Co ltd
Agency for Science Technology and Research Singapore
National University of Singapore
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201880007913.2A 2017-01-20 2018-01-18 普利多匹定用于治疗脆性x综合征的应用 Active CN110505902B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762448595P 2017-01-20 2017-01-20
US62/448,595 2017-01-20
PCT/US2018/014169 WO2018136600A1 (en) 2017-01-20 2018-01-18 Use of pridopidine for the treatment of fragile x syndrome

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CN110505902A CN110505902A (zh) 2019-11-26
CN110505902B true CN110505902B (zh) 2022-11-11

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US (2) US11234973B2 (https=)
EP (1) EP3570940B1 (https=)
JP (1) JP7114604B2 (https=)
CN (1) CN110505902B (https=)
AU (1) AU2018210145B2 (https=)
BR (1) BR112019015000A2 (https=)
CA (1) CA3050700C (https=)
DK (1) DK3570940T3 (https=)
ES (1) ES2972205T3 (https=)
HU (1) HUE068300T2 (https=)
IL (1) IL268125B2 (https=)
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WO2018039475A1 (en) 2016-08-24 2018-03-01 Teva Pharmaceuticals International Gmbh Use of pridopidine for treating dystonias
ES3025836T3 (en) 2016-08-24 2025-06-09 Prilenia Neurotherapeutics Ltd Use of pridopidine for treating functional decline
US12102627B2 (en) 2016-09-16 2024-10-01 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating rett syndrome
US12036213B2 (en) 2017-09-08 2024-07-16 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
AU2018329628B2 (en) 2017-09-08 2021-04-22 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
EP3920924A4 (en) 2019-02-04 2022-11-16 Prilenia Neurotherapeutics Ltd. LOW-DOSE PRIDOIDIN FOR THE TREATMENT OF PARKINSON'S DISEASE AND OTHER PARKINSONIC-RELATED DISEASES
KR102528677B1 (ko) * 2020-01-08 2023-05-04 주식회사 뉴로벤티 리수리드 화합물을 유효성분으로 포함하는 취약 x 증후군 또는 관련 발달 장애 치료용 조성물
CN116472043A (zh) * 2020-10-20 2023-07-21 普瑞尼亚神经治疗有限公司 普利多匹定和类似物用于治疗焦虑和抑郁的用途

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Publication number Publication date
US11234973B2 (en) 2022-02-01
US20220202798A1 (en) 2022-06-30
CA3050700C (en) 2023-10-03
AU2018210145A1 (en) 2019-08-29
CN110505902A (zh) 2019-11-26
DK3570940T3 (da) 2024-02-19
IL268125A (en) 2019-09-26
HUE068300T2 (hu) 2024-12-28
AU2018210145B2 (en) 2023-06-29
EP3570940A4 (en) 2020-10-28
BR112019015000A2 (pt) 2020-04-07
JP7114604B2 (ja) 2022-08-08
US12551474B2 (en) 2026-02-17
CA3050700A1 (en) 2018-07-26
IL268125B (en) 2022-12-01
ES2972205T3 (es) 2024-06-11
IL268125B2 (en) 2023-04-01
WO2018136600A1 (en) 2018-07-26
JP2020514313A (ja) 2020-05-21
PL3570940T3 (pl) 2024-06-17
US20190336488A1 (en) 2019-11-07
EP3570940A1 (en) 2019-11-27
EP3570940B1 (en) 2023-12-13

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