BR112019003172A2 - frações de plasma sanguíneo como tratamento para distúrbios cognitivos associados ao envelhecimento - Google Patents

frações de plasma sanguíneo como tratamento para distúrbios cognitivos associados ao envelhecimento

Info

Publication number
BR112019003172A2
BR112019003172A2 BR112019003172A BR112019003172A BR112019003172A2 BR 112019003172 A2 BR112019003172 A2 BR 112019003172A2 BR 112019003172 A BR112019003172 A BR 112019003172A BR 112019003172 A BR112019003172 A BR 112019003172A BR 112019003172 A2 BR112019003172 A2 BR 112019003172A2
Authority
BR
Brazil
Prior art keywords
blood plasma
aging
cognitive disorders
treatment
related cognitive
Prior art date
Application number
BR112019003172A
Other languages
English (en)
Inventor
Bell David
Gallager Ian
Mccracken Joe
Nikolich Karoly
Sakura Minami S
P Braithwaite Steven
Dang Vu
Original Assignee
Alkahest Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkahest Inc filed Critical Alkahest Inc
Publication of BR112019003172A2 publication Critical patent/BR112019003172A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • A61K38/385Serum albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

a presente invenção revela métodos e composições para o tratamento e/ou prevenção de condições relacionadas com o envelhecimento. as composições utilizadas nos métodos incluem frações derivadas do plasma sanguíneo com eficácia no tratamento e/ou prevenção de condições relacionadas com o envelhecimento, tais como distúrbios cognitivos.
BR112019003172A 2016-08-18 2017-04-27 frações de plasma sanguíneo como tratamento para distúrbios cognitivos associados ao envelhecimento BR112019003172A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662376529P 2016-08-18 2016-08-18
US201662412258P 2016-10-24 2016-10-24
PCT/US2017/029953 WO2018034712A1 (en) 2016-08-18 2017-04-27 Blood plasma fractions as a treatment for aging-associated cognitive disorders

Publications (1)

Publication Number Publication Date
BR112019003172A2 true BR112019003172A2 (pt) 2019-05-28

Family

ID=61196950

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019003172A BR112019003172A2 (pt) 2016-08-18 2017-04-27 frações de plasma sanguíneo como tratamento para distúrbios cognitivos associados ao envelhecimento

Country Status (28)

Country Link
US (2) US20190321449A1 (pt)
EP (2) EP3995140A1 (pt)
JP (3) JP7316931B2 (pt)
KR (3) KR20240036720A (pt)
CN (2) CN115957309A (pt)
AU (3) AU2017312722B2 (pt)
BR (1) BR112019003172A2 (pt)
CA (1) CA3033051A1 (pt)
CL (1) CL2019000304A1 (pt)
CY (1) CY1124695T1 (pt)
DK (1) DK3484502T3 (pt)
ES (1) ES2899147T3 (pt)
HR (1) HRP20211628T1 (pt)
HU (1) HUE056294T2 (pt)
IL (2) IL264660B2 (pt)
LT (1) LT3484502T (pt)
MA (1) MA45692B1 (pt)
MD (1) MD3484502T2 (pt)
MX (1) MX2019001718A (pt)
NZ (1) NZ750885A (pt)
PL (1) PL3484502T3 (pt)
PT (1) PT3484502T (pt)
RS (1) RS62558B1 (pt)
SG (1) SG11201901273TA (pt)
SI (1) SI3484502T1 (pt)
UA (1) UA126232C2 (pt)
WO (1) WO2018034712A1 (pt)
ZA (1) ZA202004834B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4299129A3 (en) * 2017-04-26 2024-03-20 Alkahest, Inc. Dosing regimen for treatment of cognitive impairments with blood plasma products
MX2020011114A (es) 2018-05-15 2021-01-29 Alkahest Inc Tratamiento de enfermedades asociadas con el envejecimiento con moduladores de la leucotrieno a4 hidrolasa.
CN110724176B (zh) * 2018-07-16 2021-10-26 北京豪思生物科技有限公司 一种治疗阿尔茨海默症的血浆蛋白分离物及其制备方法和应用
CN110787187B (zh) * 2018-07-16 2022-05-13 北京豪思生物科技股份有限公司 一种增强记忆力和提高认知功能的血浆混合物及其制备方法和应用
WO2020018343A1 (en) * 2018-07-20 2020-01-23 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
JP2022505915A (ja) 2018-10-26 2022-01-14 アルカヘスト,インコーポレイテッド 疼痛、創傷治癒及び術後回復の改善のための血漿及び血漿画分の使用
CN110448686B (zh) * 2019-09-19 2022-11-04 北京豪思生物科技股份有限公司 铜蓝蛋白联合运铁蛋白的应用
WO2021062007A1 (en) * 2019-09-25 2021-04-01 Cytegen Corp. Treatment of mitochondrial deficits and age-related diseases using blood products
CA3151943A1 (en) 2019-11-04 2021-05-14 Viktoria Kheifets Blood plasma fractions for use in muscle regeneration
US11484551B2 (en) 2019-11-20 2022-11-01 Alkahest, Inc. Method of treating liver failure with plasma fraction IV-4
CN114746100A (zh) 2019-11-20 2022-07-12 万能溶剂有限公司 用于肝再生的血浆级分
CA3221177A1 (en) 2021-11-01 2023-05-04 Meghan Kerrisk Campbell Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3869431A (en) 1973-03-12 1975-03-04 Firestone Tire & Rubber Co Polyamides and their production
US4624780A (en) 1982-06-28 1986-11-25 Alpha Therapeutic Corporation Fractionation of blood plasma
DE3612137A1 (de) * 1986-04-10 1987-10-15 Biotest Pharma Gmbh Steriles plasmaaustauschmittel
US5138034A (en) * 1989-07-12 1992-08-11 The Green Cross Corporation Method of fractionating plasma proteins
US5110907A (en) 1989-08-01 1992-05-05 Alpha Therapeutic Corporation Factor viii complex purification using heparin affinity chromatography
US5288853A (en) 1992-04-30 1994-02-22 Alpha Therapeutic Corporation Factor viii purification process
US5219995A (en) 1992-07-14 1993-06-15 Alpha Therapeutic Corporation Plasma fraction purification
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
US20050143310A1 (en) * 2001-05-11 2005-06-30 Masaki Hirashima Novel remedies for neurodegenerative disease
US20070010435A1 (en) * 2002-12-19 2007-01-11 New York University Method for treating amyloid disease
US20040146565A1 (en) * 2003-01-28 2004-07-29 Lauridsen Group Incorporated First lipoprotein fraction and therapeutic compositions of same
US20130121979A1 (en) * 2003-12-29 2013-05-16 Allan Mishra Method of treating cancer using platelet compositions
ES2257225B1 (es) 2006-02-17 2007-03-16 Grifols, S.A Preparacion terapeutica de fviia de muy alta pureza y metodo para su obtencion.
ES2332846B1 (es) * 2007-10-26 2010-07-08 Grifols, S.A. Utilizacion de albumina humana terapeutica para la preparacion de un medicamento para el tratamiento de pacientes afectados por desordenes cognitivos.
PT2271382E (pt) 2008-04-15 2013-05-07 Grifols Therapeutics Inc Ultrafiltração em dois andares/diafiltração
US20090297485A1 (en) * 2008-05-28 2009-12-03 Allan Mishra Compositions and methods for treating psychiatric and neurodegenerative disorders
AU2013203043B2 (en) * 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
WO2014182631A1 (en) * 2013-05-06 2014-11-13 Baxter International Inc. Treatment of alzheimer's disease subpopulations with pooled immunoglobulin g
CN106163530A (zh) * 2013-12-09 2016-11-23 小利兰·斯坦福大学托管委员会 用于治疗衰老相关病症的方法和组合物
ES2524516B1 (es) 2014-05-29 2015-03-31 Grifols Worldwide Operations Limited Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido
EA039316B1 (ru) * 2016-10-24 2022-01-12 Алкахест, Инк. Фракции плазмы крови в качестве лечения когнитивных расстройств, связанных со старением
US11040068B2 (en) * 2017-04-26 2021-06-22 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
EP4299129A3 (en) * 2017-04-26 2024-03-20 Alkahest, Inc. Dosing regimen for treatment of cognitive impairments with blood plasma products

Also Published As

Publication number Publication date
JP7316931B2 (ja) 2023-07-28
LT3484502T (lt) 2021-12-10
PT3484502T (pt) 2021-11-18
ZA202004834B (en) 2022-07-27
HRP20211628T1 (hr) 2022-02-04
EP3484502B1 (en) 2021-08-25
AU2020200181A1 (en) 2020-01-30
PL3484502T3 (pl) 2022-01-31
SI3484502T1 (sl) 2022-01-31
MA45692A (fr) 2019-05-22
MA45692B1 (fr) 2021-10-29
SG11201901273TA (en) 2019-03-28
JP2019528269A (ja) 2019-10-10
EP3995140A1 (en) 2022-05-11
KR20240036720A (ko) 2024-03-20
ES2899147T3 (es) 2022-03-10
CN109963582A (zh) 2019-07-02
IL264660B1 (en) 2023-11-01
MX2019001718A (es) 2019-09-13
CN115957309A (zh) 2023-04-14
JP2023156459A (ja) 2023-10-24
CA3033051A1 (en) 2018-02-22
CY1124695T1 (el) 2022-07-22
RS62558B1 (sr) 2021-12-31
JP2022037124A (ja) 2022-03-08
JP7447069B2 (ja) 2024-03-11
DK3484502T3 (da) 2021-10-25
US20220152161A1 (en) 2022-05-19
AU2017312722A1 (en) 2019-03-14
IL264660B2 (en) 2024-03-01
WO2018034712A1 (en) 2018-02-22
AU2017312722B2 (en) 2020-01-02
UA126232C2 (uk) 2022-09-07
KR20220107322A (ko) 2022-08-02
AU2021240142A1 (en) 2021-10-28
EP3484502A1 (en) 2019-05-22
EP3484502A4 (en) 2020-03-04
IL264660A (pt) 2019-04-30
HUE056294T2 (hu) 2022-02-28
NZ750885A (en) 2021-07-30
MD3484502T2 (ro) 2022-01-31
KR20190032614A (ko) 2019-03-27
AU2020200181B2 (en) 2021-07-22
US20190321449A1 (en) 2019-10-24
IL304946A (en) 2023-10-01
CN109963582B (zh) 2022-12-27
CL2019000304A1 (es) 2019-05-31

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Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements