DK3484502T3 - Blodplasmafraktioner til behandling mod aldersrelaterede kognitive forstyrrelser - Google Patents

Blodplasmafraktioner til behandling mod aldersrelaterede kognitive forstyrrelser Download PDF

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Publication number
DK3484502T3
DK3484502T3 DK17841780.4T DK17841780T DK3484502T3 DK 3484502 T3 DK3484502 T3 DK 3484502T3 DK 17841780 T DK17841780 T DK 17841780T DK 3484502 T3 DK3484502 T3 DK 3484502T3
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Denmark
Prior art keywords
blood plasma
cognitive disorders
related cognitive
treatment against
plasma fractions
Prior art date
Application number
DK17841780.4T
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English (en)
Inventor
Karoly Nikolich
Ian Gallager
Steven P Braithwaite
S Sakura Minami
Vu Dang
David Bell
Joe Mccracken
Original Assignee
Alkahest Inc
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Publication of DK3484502T3 publication Critical patent/DK3484502T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • A61K38/385Serum albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK17841780.4T 2016-08-18 2017-04-27 Blodplasmafraktioner til behandling mod aldersrelaterede kognitive forstyrrelser DK3484502T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662376529P 2016-08-18 2016-08-18
US201662412258P 2016-10-24 2016-10-24
PCT/US2017/029953 WO2018034712A1 (en) 2016-08-18 2017-04-27 Blood plasma fractions as a treatment for aging-associated cognitive disorders

Publications (1)

Publication Number Publication Date
DK3484502T3 true DK3484502T3 (da) 2021-10-25

Family

ID=61196950

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17841780.4T DK3484502T3 (da) 2016-08-18 2017-04-27 Blodplasmafraktioner til behandling mod aldersrelaterede kognitive forstyrrelser

Country Status (28)

Country Link
US (2) US20190321449A1 (da)
EP (2) EP3995140A1 (da)
JP (3) JP7316931B2 (da)
KR (3) KR20190032614A (da)
CN (2) CN115957309A (da)
AU (4) AU2017312722B2 (da)
BR (1) BR112019003172A2 (da)
CA (1) CA3033051A1 (da)
CL (1) CL2019000304A1 (da)
CY (1) CY1124695T1 (da)
DK (1) DK3484502T3 (da)
ES (1) ES2899147T3 (da)
HR (1) HRP20211628T1 (da)
HU (1) HUE056294T2 (da)
IL (2) IL304946A (da)
LT (1) LT3484502T (da)
MA (1) MA45692B1 (da)
MD (1) MD3484502T2 (da)
MX (2) MX2019001718A (da)
NZ (1) NZ750885A (da)
PL (1) PL3484502T3 (da)
PT (1) PT3484502T (da)
RS (1) RS62558B1 (da)
SG (1) SG11201901273TA (da)
SI (1) SI3484502T1 (da)
UA (1) UA126232C2 (da)
WO (1) WO2018034712A1 (da)
ZA (1) ZA202004834B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3615057T3 (da) * 2017-04-26 2024-01-02 Alkahest Inc Doseringsskema til behandling af kognitive svækkelser med blodplasmaprodukter
SG11202010115RA (en) 2018-05-15 2020-11-27 Alkahest Inc Treatment of aging-associated disease with modulators of leukotriene a4 hydrolase
CN110724176B (zh) * 2018-07-16 2021-10-26 北京豪思生物科技有限公司 一种治疗阿尔茨海默症的血浆蛋白分离物及其制备方法和应用
CN110787187B (zh) * 2018-07-16 2022-05-13 北京豪思生物科技股份有限公司 一种增强记忆力和提高认知功能的血浆混合物及其制备方法和应用
EP4374921A3 (en) * 2018-07-20 2024-06-19 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
JP7504090B2 (ja) 2018-10-26 2024-06-21 アルカヘスト,インコーポレイテッド 疼痛、創傷治癒及び術後回復の改善のための血漿及び血漿画分の使用
CN110448686B (zh) * 2019-09-19 2022-11-04 北京豪思生物科技股份有限公司 铜蓝蛋白联合运铁蛋白的应用
WO2021062007A1 (en) * 2019-09-25 2021-04-01 Cytegen Corp. Treatment of mitochondrial deficits and age-related diseases using blood products
US11439687B2 (en) 2019-11-04 2022-09-13 Alkahest, Inc. Blood plasma fractions for use in muscle regeneration
US11484551B2 (en) 2019-11-20 2022-11-01 Alkahest, Inc. Method of treating liver failure with plasma fraction IV-4
CA3156906A1 (en) 2019-11-20 2021-05-27 Alkahest, Inc. Blood plasma fractions for use in liver regeneration
EP4426284A1 (en) 2021-11-01 2024-09-11 Alkahest, Inc. Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases
WO2024102244A1 (en) * 2022-11-11 2024-05-16 Alkahest, Inc. Blood plasma fractions for improvement of myelination

Family Cites Families (23)

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US3869431A (en) 1973-03-12 1975-03-04 Firestone Tire & Rubber Co Polyamides and their production
US4624780A (en) 1982-06-28 1986-11-25 Alpha Therapeutic Corporation Fractionation of blood plasma
DE3612137A1 (de) * 1986-04-10 1987-10-15 Biotest Pharma Gmbh Steriles plasmaaustauschmittel
US5138034A (en) * 1989-07-12 1992-08-11 The Green Cross Corporation Method of fractionating plasma proteins
US5110907A (en) 1989-08-01 1992-05-05 Alpha Therapeutic Corporation Factor viii complex purification using heparin affinity chromatography
US5288853A (en) 1992-04-30 1994-02-22 Alpha Therapeutic Corporation Factor viii purification process
US5219995A (en) 1992-07-14 1993-06-15 Alpha Therapeutic Corporation Plasma fraction purification
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
US20050143310A1 (en) * 2001-05-11 2005-06-30 Masaki Hirashima Novel remedies for neurodegenerative disease
AU2003303198A1 (en) * 2002-12-19 2004-07-14 New York University Method for treating amyloid disease
US20040146565A1 (en) * 2003-01-28 2004-07-29 Lauridsen Group Incorporated First lipoprotein fraction and therapeutic compositions of same
US20130121979A1 (en) * 2003-12-29 2013-05-16 Allan Mishra Method of treating cancer using platelet compositions
ES2257225B1 (es) 2006-02-17 2007-03-16 Grifols, S.A Preparacion terapeutica de fviia de muy alta pureza y metodo para su obtencion.
ES2332846B1 (es) * 2007-10-26 2010-07-08 Grifols, S.A. Utilizacion de albumina humana terapeutica para la preparacion de un medicamento para el tratamiento de pacientes afectados por desordenes cognitivos.
EP2271382B1 (en) 2008-04-15 2013-03-13 Grifols Therapeutics Inc. Two-stage ultrafiltration/diafiltration
WO2009155069A1 (en) * 2008-05-28 2009-12-23 Allan Mishra Compositions and methods for treating psychiatric and neurodegenerative disorders
AU2013203043B2 (en) * 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
PT2994160T (pt) * 2013-05-06 2019-08-07 Baxalta Inc Tratamento de sub-populações com doença de alzheimer com imunoglobulina g combinada
AU2014364182B2 (en) * 2013-12-09 2019-03-07 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating aging-associated conditions
ES2524516B1 (es) 2014-05-29 2015-03-31 Grifols Worldwide Operations Limited Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido
EA039316B1 (ru) * 2016-10-24 2022-01-12 Алкахест, Инк. Фракции плазмы крови в качестве лечения когнитивных расстройств, связанных со старением
US11040068B2 (en) * 2017-04-26 2021-06-22 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
DK3615057T3 (da) * 2017-04-26 2024-01-02 Alkahest Inc Doseringsskema til behandling af kognitive svækkelser med blodplasmaprodukter

Also Published As

Publication number Publication date
ES2899147T3 (es) 2022-03-10
CY1124695T1 (el) 2022-07-22
EP3995140A1 (en) 2022-05-11
RS62558B1 (sr) 2021-12-31
WO2018034712A1 (en) 2018-02-22
MA45692B1 (fr) 2021-10-29
AU2017312722B2 (en) 2020-01-02
CA3033051A1 (en) 2018-02-22
IL264660B2 (en) 2024-03-01
HUE056294T2 (hu) 2022-02-28
NZ750885A (en) 2021-07-30
MX2024008963A (es) 2024-07-30
US20220152161A1 (en) 2022-05-19
LT3484502T (lt) 2021-12-10
JP7316931B2 (ja) 2023-07-28
CL2019000304A1 (es) 2019-05-31
JP2023156459A (ja) 2023-10-24
BR112019003172A2 (pt) 2019-05-28
ZA202004834B (en) 2022-07-27
KR20190032614A (ko) 2019-03-27
AU2020200181A1 (en) 2020-01-30
PT3484502T (pt) 2021-11-18
AU2024219765A1 (en) 2024-10-10
HRP20211628T1 (hr) 2022-02-04
MX2019001718A (es) 2019-09-13
PL3484502T3 (pl) 2022-01-31
KR20220107322A (ko) 2022-08-02
AU2021240142B2 (en) 2024-06-20
AU2020200181B2 (en) 2021-07-22
EP3484502B1 (en) 2021-08-25
JP7447069B2 (ja) 2024-03-11
IL304946A (en) 2023-10-01
MA45692A (fr) 2019-05-22
MD3484502T2 (ro) 2022-01-31
SI3484502T1 (sl) 2022-01-31
AU2017312722A1 (en) 2019-03-14
CN109963582B (zh) 2022-12-27
IL264660A (da) 2019-04-30
EP3484502A1 (en) 2019-05-22
EP3484502A4 (en) 2020-03-04
SG11201901273TA (en) 2019-03-28
JP2019528269A (ja) 2019-10-10
JP2022037124A (ja) 2022-03-08
KR20240036720A (ko) 2024-03-20
CN109963582A (zh) 2019-07-02
IL264660B1 (en) 2023-11-01
CN115957309A (zh) 2023-04-14
US20190321449A1 (en) 2019-10-24
UA126232C2 (uk) 2022-09-07
AU2021240142A1 (en) 2021-10-28

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