BR112015023207A8 - composições de ci-inh e métodos para prevenção e tratamento de desordens associadas à deficiência de inibidor de c1 esterase. - Google Patents

composições de ci-inh e métodos para prevenção e tratamento de desordens associadas à deficiência de inibidor de c1 esterase.

Info

Publication number
BR112015023207A8
BR112015023207A8 BR112015023207A BR112015023207A BR112015023207A8 BR 112015023207 A8 BR112015023207 A8 BR 112015023207A8 BR 112015023207 A BR112015023207 A BR 112015023207A BR 112015023207 A BR112015023207 A BR 112015023207A BR 112015023207 A8 BR112015023207 A8 BR 112015023207A8
Authority
BR
Brazil
Prior art keywords
prevention
treatment
methods
compositions
esterase inhibitor
Prior art date
Application number
BR112015023207A
Other languages
English (en)
Other versions
BR112015023207A2 (pt
Inventor
Gallagher Cynthia
Cornell Manning Mark
Ruddy Steven
Original Assignee
Shire Viropharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51538486&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112015023207(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Shire Viropharma Inc filed Critical Shire Viropharma Inc
Publication of BR112015023207A2 publication Critical patent/BR112015023207A2/pt
Publication of BR112015023207A8 publication Critical patent/BR112015023207A8/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors

Abstract

resumo composições de cl-inh e métodos para prevenção e tratamento de desordens associadas à deficiência de inibidor de c1 esterase composições e métodos para o tratamento e/ou prevenção de desordens associadas a deficiência de inibidor de c1 esterase são divulgados.
BR112015023207A 2013-03-15 2014-03-17 composições de ci-inh e métodos para prevenção e tratamento de desordens associadas à deficiência de inibidor de c1 esterase. BR112015023207A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361791399P 2013-03-15 2013-03-15
PCT/US2014/030309 WO2014145519A2 (en) 2013-03-15 2014-03-17 C1-inh compositions and methods for the prevention and treatment of disorders associated with c1 esterase inhibitor deficency

Publications (2)

Publication Number Publication Date
BR112015023207A2 BR112015023207A2 (pt) 2017-11-21
BR112015023207A8 true BR112015023207A8 (pt) 2018-01-23

Family

ID=51538486

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015023207A BR112015023207A8 (pt) 2013-03-15 2014-03-17 composições de ci-inh e métodos para prevenção e tratamento de desordens associadas à deficiência de inibidor de c1 esterase.

Country Status (30)

Country Link
US (9) US9616111B2 (pt)
EP (3) EP3290046B1 (pt)
JP (9) JP6184581B2 (pt)
KR (4) KR102430453B1 (pt)
CN (2) CN111529708A (pt)
AU (3) AU2014232912A1 (pt)
BR (1) BR112015023207A8 (pt)
CA (2) CA3054718A1 (pt)
CY (2) CY1119419T1 (pt)
DE (1) DE202014011208U1 (pt)
DK (2) DK3290046T3 (pt)
EA (1) EA201591278A1 (pt)
ES (2) ES2713004T3 (pt)
GB (1) GB2530921B (pt)
HK (2) HK1220403A1 (pt)
HR (2) HRP20171269T1 (pt)
HU (2) HUE036224T2 (pt)
IL (2) IL241549B (pt)
LT (2) LT3290046T (pt)
ME (2) ME03326B (pt)
MX (3) MX2020004724A (pt)
NZ (2) NZ751555A (pt)
PL (2) PL2968434T3 (pt)
PT (2) PT3290046T (pt)
RS (2) RS56285B1 (pt)
SG (2) SG11201507616VA (pt)
SI (2) SI2968434T1 (pt)
TR (1) TR201900319T4 (pt)
WO (1) WO2014145519A2 (pt)
ZA (3) ZA201507604B (pt)

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US20190160158A1 (en) 2019-05-30
DE202014011208U1 (de) 2018-08-23
HRP20190270T1 (hr) 2019-04-05
ZA201706929B (en) 2019-05-29
JP2021088599A (ja) 2021-06-10
ZA201507604B (en) 2018-05-30
JP2017105847A (ja) 2017-06-15
LT3290046T (lt) 2019-03-12
EP2968434A2 (en) 2016-01-20
US11364288B2 (en) 2022-06-21
US20160015795A1 (en) 2016-01-21
US11534482B2 (en) 2022-12-27
JP6877471B2 (ja) 2021-05-26
EP2968434A4 (en) 2016-03-02
JP2018119001A (ja) 2018-08-02
WO2014145519A2 (en) 2014-09-18
CY1119419T1 (el) 2018-03-07
JP6473535B2 (ja) 2019-02-20
JP2019073546A (ja) 2019-05-16
JP2019073544A (ja) 2019-05-16
CA3054718A1 (en) 2014-09-18
HUE036224T2 (hu) 2018-06-28
KR20220070049A (ko) 2022-05-27
KR102430453B1 (ko) 2022-08-05
CN105517559A (zh) 2016-04-20
PL3290046T3 (pl) 2019-05-31
GB2530921A (en) 2016-04-06
BR112015023207A2 (pt) 2017-11-21
GB201519921D0 (en) 2015-12-23
CY1121653T1 (el) 2020-07-31
US10080788B2 (en) 2018-09-25
AU2020203183B2 (en) 2022-06-02
JP2018119000A (ja) 2018-08-02
MX2020004724A (es) 2022-01-18
ES2639833T3 (es) 2017-10-30
US20200261556A1 (en) 2020-08-20
JP6877472B2 (ja) 2021-05-26
HRP20171269T1 (hr) 2017-11-03
AU2020203183A1 (en) 2020-06-04
KR20150135242A (ko) 2015-12-02
RS58351B1 (sr) 2019-03-29
RS56285B1 (sr) 2017-12-29
US10201595B2 (en) 2019-02-12
US20180110843A1 (en) 2018-04-26
HK1250912B (zh) 2020-01-10
MX2015011281A (es) 2016-03-03
US20190160157A1 (en) 2019-05-30
LT2968434T (lt) 2017-09-25
US9616111B2 (en) 2017-04-11
GB2530921B (en) 2017-09-20
PT3290046T (pt) 2019-02-18
KR20210021146A (ko) 2021-02-24
SI2968434T1 (sl) 2017-11-30
CA2904543C (en) 2019-10-08
IL276153B (en) 2022-06-01
PL2968434T3 (pl) 2018-01-31
SG10201707598QA (en) 2017-10-30
AU2014232912A1 (en) 2015-09-03
JP6184581B2 (ja) 2017-08-23
AU2018229558B2 (en) 2020-03-05
IL241549B (en) 2020-08-31
CN111529708A (zh) 2020-08-14
SG11201507616VA (en) 2015-10-29
PT2968434T (pt) 2017-09-18
EP2968434B1 (en) 2017-06-28
JP2016516073A (ja) 2016-06-02
JP2019073545A (ja) 2019-05-16
JP6473534B2 (ja) 2019-02-20
DK3290046T3 (en) 2019-03-18
ME03326B (me) 2019-10-20
HUE041837T2 (hu) 2019-05-28
US20180085441A1 (en) 2018-03-29
EA201591278A1 (ru) 2016-03-31
NZ751555A (en) 2021-07-30
US20180153972A1 (en) 2018-06-07
ZA201806793B (en) 2020-01-29
JP6473536B2 (ja) 2019-02-20
KR102579789B1 (ko) 2023-09-15
JP2018119002A (ja) 2018-08-02
US10105423B2 (en) 2018-10-23
IL276153A (en) 2020-09-30
EP3290046B1 (en) 2019-01-02
JP6877470B2 (ja) 2021-05-26
CA2904543A1 (en) 2014-09-18
WO2014145519A3 (en) 2014-12-31
SI3290046T1 (sl) 2019-04-30
KR20210129267A (ko) 2021-10-27
ME02865B (me) 2018-04-20
NZ710730A (en) 2021-07-30
US10130690B2 (en) 2018-11-20
DK2968434T3 (en) 2017-09-11
HK1220403A1 (zh) 2017-05-05
AU2018229558A1 (en) 2018-10-04
MX2021011946A (es) 2021-11-17
ES2713004T3 (es) 2019-05-17
TR201900319T4 (tr) 2019-02-21
EP3508213A1 (en) 2019-07-10
US20170224788A1 (en) 2017-08-10
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US20180110844A1 (en) 2018-04-26
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