BR112019002979B1 - Método de cromatografia para quantificação de um tensoativo não iônico em uma composição compreendendo o tensoativo não iônico e um polipeptídeo - Google Patents
Método de cromatografia para quantificação de um tensoativo não iônico em uma composição compreendendo o tensoativo não iônico e um polipeptídeo Download PDFInfo
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
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| US20210139387A1 (en) * | 2016-01-19 | 2021-05-13 | Genebiologics, Llc | Production of Arginine-Rich Proteins from Wastewater and Use as a Fertilizer |
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| TWI870390B (zh) * | 2019-02-27 | 2025-01-21 | 法商賽諾菲公司 | 以具內標之lc-ms於樣品中進行聚山梨醇酯定量之方法 |
| CN113424057B (zh) * | 2019-04-19 | 2024-04-05 | 海正生物制药有限公司 | 组合物中泊洛沙姆188的检测方法 |
| JP2022531317A (ja) | 2019-05-03 | 2022-07-06 | ジェネンテック， インコーポレイテッド | 精製プラットフォームから得られた組成物中の酵素加水分解活性速度を低下させる方法 |
| EP4090666A1 (en) | 2020-01-15 | 2022-11-23 | F. Hoffmann-La Roche AG | Methods to decrease impurities from recombinant protein manufacturing processes |
| CA3198684A1 (en) | 2020-10-30 | 2022-05-05 | Genentech, Inc. | Purification platforms for obtaining pharmaceutical compositions having a reduced hydrolytic enzyme activity rate |
| BR112023016996A2 (pt) | 2021-02-24 | 2023-09-26 | Hoffmann La Roche | Métodos para purificar um polipeptídeo terapêutico e para produzir um polipeptídeo terapêutico e usos de uma solução ácida e de uma solução alcalina |
| KR102283871B1 (ko) * | 2021-03-02 | 2021-08-02 | 한국원자력연구원 | 크로마토그래피를 이용한 무담체 홀뮴-166의 분리 방법, 분리 장치 및 이에 의하여 분리된 무담체 홀뮴-166 |
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| JP5193266B2 (ja) | 2010-11-16 | 2013-05-08 | 株式会社ミノファーゲン製薬 | 生薬由来成分の高感度定量方法 |
| SG10201606218WA (en) * | 2011-07-29 | 2016-09-29 | Eleven Biotherapeutics Inc | Purified Proteins |
| HUE035685T2 (en) * | 2011-11-02 | 2018-05-28 | Hoffmann La Roche | Overload and elute chromatography |
| JP6129302B2 (ja) * | 2012-05-23 | 2017-05-17 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 混合物中のポリソルベート種の濃度を決定するための方法 |
| HRP20250718T1 (hr) | 2016-08-15 | 2025-08-15 | F. Hoffmann-La Roche Ag | Kromatografski postupak za kvantifikaciju neionskog surfaktanta u sastavu koji sadrži neionski surfaktant i polipeptid |
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