BR112018071284A2 - forma sólida do (-) ambrox formada pela bioconversão do homofarnesol na presença de um biocatalisador - Google Patents

forma sólida do (-) ambrox formada pela bioconversão do homofarnesol na presença de um biocatalisador

Info

Publication number
BR112018071284A2
BR112018071284A2 BR112018071284-1A BR112018071284A BR112018071284A2 BR 112018071284 A2 BR112018071284 A2 BR 112018071284A2 BR 112018071284 A BR112018071284 A BR 112018071284A BR 112018071284 A2 BR112018071284 A2 BR 112018071284A2
Authority
BR
Brazil
Prior art keywords
bioconversion
solid form
homopharnesol
biocatalyst
ambrox
Prior art date
Application number
BR112018071284-1A
Other languages
English (en)
Portuguese (pt)
Inventor
SANHAJI Ghislain
ROUSSEAUX Alix
NOEL Sandrine
EICHHORN Eric
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2016/058997 external-priority patent/WO2016170106A1/en
Priority claimed from PCT/EP2016/058987 external-priority patent/WO2016170099A1/en
Application filed by Givaudan Sa filed Critical Givaudan Sa
Publication of BR112018071284A2 publication Critical patent/BR112018071284A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/99—Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99017—Squalene--hopene cyclase (5.4.99.17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Furan Compounds (AREA)
  • Cosmetics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
  • Detergent Compositions (AREA)
BR112018071284-1A 2016-04-22 2017-04-20 forma sólida do (-) ambrox formada pela bioconversão do homofarnesol na presença de um biocatalisador BR112018071284A2 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
PCT/EP2016/058997 WO2016170106A1 (en) 2015-04-24 2016-04-22 Process for isolating and purifying ambrox
PCT/EP2016/058987 WO2016170099A1 (en) 2015-04-24 2016-04-22 Enzymes and applications thereof
EPPCT/EP2016/058987 2016-04-22
EPPCT/EP2016/058997 2016-04-22
GB1618090.3 2016-10-26
GBGB1618090.3A GB201618090D0 (en) 2016-10-26 2016-10-26 Product
PCT/EP2017/059327 WO2017182542A1 (en) 2016-04-22 2017-04-20 A solid form of (-)-ambrox formed by a bioverversion of homofarnesol in the presence of a biocatalyst

Publications (1)

Publication Number Publication Date
BR112018071284A2 true BR112018071284A2 (pt) 2019-02-12

Family

ID=57738295

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018071284-1A BR112018071284A2 (pt) 2016-04-22 2017-04-20 forma sólida do (-) ambrox formada pela bioconversão do homofarnesol na presença de um biocatalisador

Country Status (12)

Country Link
US (5) US10844412B2 (cg-RX-API-DMAC7.html)
EP (1) EP3445755B1 (cg-RX-API-DMAC7.html)
JP (4) JP7407513B2 (cg-RX-API-DMAC7.html)
CN (2) CN109071480B (cg-RX-API-DMAC7.html)
BR (1) BR112018071284A2 (cg-RX-API-DMAC7.html)
CO (1) CO2018011292A2 (cg-RX-API-DMAC7.html)
GB (1) GB201618090D0 (cg-RX-API-DMAC7.html)
IL (5) IL320763A (cg-RX-API-DMAC7.html)
MX (2) MX2018012836A (cg-RX-API-DMAC7.html)
RU (1) RU2018136063A (cg-RX-API-DMAC7.html)
SG (1) SG11201808643SA (cg-RX-API-DMAC7.html)
WO (1) WO2017182542A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201618090D0 (en) * 2016-10-26 2016-12-07 Givaudan Sa Product
GB201917694D0 (en) 2019-12-04 2020-01-15 Givaudan Sa Enzyme mediated process
GB201917688D0 (en) 2019-12-04 2020-01-15 Givaudan Sa SHC enzymes and enzyme variants
GB202011823D0 (en) 2020-07-30 2020-09-16 Givaudan Sa Method
GB202020331D0 (en) * 2020-12-22 2021-02-03 Givaudan Sa Process of making organic compounds
WO2023175123A1 (en) 2022-03-17 2023-09-21 Givaudan Sa Shc enzymes and enzyme variants
WO2024097746A1 (en) * 2022-11-01 2024-05-10 Conagen Inc. Alkene cyclopropanation with nickel catalyst enhancer and improved rearrangement reaction

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4123767C2 (de) * 1991-07-18 1993-11-18 Henkel Kgaa Verfahren zur Herstellung von Stereoisomerengemischen von 8,12-Oxido-13,14,15,16-tetranorlabdan
DE69213916T2 (de) * 1991-12-29 1997-03-06 Kuraray Co Verfahren zur Herstellung von L-Ambrox
DE19649655A1 (de) 1996-11-29 1998-06-04 Haarmann & Reimer Gmbh Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung
US6180121B1 (en) * 1998-03-05 2001-01-30 Colgate-Palmolive Company Fragrance enhancing compositions for cosmetic products
DE19960106A1 (de) 1999-12-14 2001-06-21 Haarmann & Reimer Gmbh Enzyme und Gene für die Herstellung von Vanillin
US20040265850A1 (en) 2002-12-02 2004-12-30 Hua Wang Rapid detection of microorganisms
AU2003302326A1 (en) 2002-12-02 2004-08-10 The Ohio State University Research Foundation Rapid detection of microorganisms
JP4598692B2 (ja) * 2006-02-24 2010-12-15 花王株式会社 新規微生物、当該新規微生物を用いたドデカヒドロ−３ａ，６，６，９ａ−テトラメチルナフト［２，１−ｂ］フラン中間体の製造方法
JP4156655B2 (ja) * 2006-07-31 2008-09-24 花王株式会社 （±）−３ａ、６、６、９ａ−テトラメチルデカヒドロナフト［２、１−ｂ］フラン−２（１Ｈ）−オン類の製造方法
JP5236233B2 (ja) * 2007-09-04 2013-07-17 花王株式会社 （−）−アンブロキサンの製造方法
WO2010139710A1 (de) 2009-06-05 2010-12-09 Basf Se Verbundteile enthaltend plastisch verformbaren polyurethanhartschaumstoff, klebstoff und abdeckmaterial
WO2010139719A2 (de) 2009-06-05 2010-12-09 Basf Se Biokatalytische herstellung von ambroxan
US8935839B2 (en) 2010-02-19 2015-01-20 Owen V. Burt Ballistic enhanced battering ram
ES2925777T3 (es) 2010-11-17 2022-10-19 Basf Se Procedimiento para la ciclación biocatalítica de terpenos y mutantes de ciclasa que pueden usarse en el mismo
US8932839B2 (en) 2010-11-17 2015-01-13 Basf Se Method for the biocatalytic cyclization of terpenes and cyclase mutants employable therein
JP2013132226A (ja) * 2011-12-26 2013-07-08 Kao Corp （−）−３ａ，６，６，９ａ−テトラメチルドデカヒドロナフト［２，１−ｂ］フランの製造方法
ES2602190T3 (es) * 2012-04-16 2017-02-20 Basf Se Procedimiento para la preparación de (3E, 7E)-homofarnesol
US20130273619A1 (en) 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol
US9902979B2 (en) 2013-09-05 2018-02-27 Niigata University Method for producing ambrein
GB201318886D0 (en) 2013-10-25 2013-12-11 Givaudan Sa Improvements i or relating to organic compounds
GB201318894D0 (en) * 2013-10-25 2013-12-11 Givaudan Sa Improvements in or relating to organic compounds
GB201507207D0 (en) * 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
GB201507170D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Process
CN105037308B (zh) * 2015-07-06 2017-06-06 四川中烟工业有限责任公司 一种制备降龙涎香醚的方法
MX361536B (es) * 2015-10-23 2018-12-10 Univ Michoacana De San Nicolas De Hidalgo Proceso de sintesis de ambrox a partir de ageratina jocotepecana.
CN105418566B (zh) * 2015-11-27 2018-02-09 北京工商大学 降龙涎醚的一种合成方法
GB201618090D0 (en) * 2016-10-26 2016-12-07 Givaudan Sa Product

Also Published As

Publication number Publication date
JP2019521952A (ja) 2019-08-08
US20210040521A1 (en) 2021-02-11
EP3445755B1 (en) 2026-01-07
EP3445755A1 (en) 2019-02-27
SG11201808643SA (en) 2018-11-29
JP7723048B2 (ja) 2025-08-13
IL262393B (en) 2022-03-01
CN109071480B (zh) 2022-11-29
IL310388B2 (en) 2025-10-01
IL290606B1 (en) 2023-10-01
CO2018011292A2 (es) 2018-11-13
JP2025183197A (ja) 2025-12-16
JP7407513B2 (ja) 2024-01-04
CN109071480A (zh) 2018-12-21
US10844412B2 (en) 2020-11-24
JP7343564B2 (ja) 2023-09-12
US20190136275A1 (en) 2019-05-09
US11773419B2 (en) 2023-10-03
JP2023179438A (ja) 2023-12-19
CN115819385A (zh) 2023-03-21
US20220177935A1 (en) 2022-06-09
IL310388A (en) 2024-03-01
IL304330B2 (en) 2024-07-01
IL310388B1 (en) 2025-06-01
WO2017182542A1 (en) 2017-10-26
CN115819385B (zh) 2025-05-13
RU2018136063A (ru) 2020-05-22
IL320763A (en) 2025-07-01
IL262393A (en) 2018-12-31
IL304330A (en) 2023-09-01
JP2022061977A (ja) 2022-04-19
US20230357809A1 (en) 2023-11-09
US20240401094A1 (en) 2024-12-05
MX2023014907A (es) 2024-02-15
US11401541B2 (en) 2022-08-02
MX2018012836A (es) 2019-03-11
RU2018136063A3 (cg-RX-API-DMAC7.html) 2020-07-13
IL290606B2 (en) 2024-02-01
US12084699B2 (en) 2024-09-10
IL290606A (en) 2022-04-01
IL304330B1 (en) 2024-03-01
GB201618090D0 (en) 2016-12-07

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B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]