IL320763A - Solid form of (-)-ambrox produced via bioconversion of homoferon in the presence of a biocatalyst - Google Patents

Solid form of (-)-ambrox produced via bioconversion of homoferon in the presence of a biocatalyst

Info

Publication number
IL320763A
IL320763A IL320763A IL32076325A IL320763A IL 320763 A IL320763 A IL 320763A IL 320763 A IL320763 A IL 320763A IL 32076325 A IL32076325 A IL 32076325A IL 320763 A IL320763 A IL 320763A
Authority
IL
Israel
Prior art keywords
ambrox
homofarnesol
bioconversion
solid form
medium
Prior art date
Application number
IL320763A
Other languages
English (en)
Hebrew (he)
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2016/058997 external-priority patent/WO2016170106A1/en
Priority claimed from PCT/EP2016/058987 external-priority patent/WO2016170099A1/en
Application filed by Givaudan Sa filed Critical Givaudan Sa
Publication of IL320763A publication Critical patent/IL320763A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/04Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00Formulations or additives for perfume preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92Naphthofurans; Hydrogenated naphthofurans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y504/00Intramolecular transferases (5.4)
    • C12Y504/99Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99017Squalene--hopene cyclase (5.4.99.17)

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Furan Compounds (AREA)
  • Cosmetics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
  • Detergent Compositions (AREA)
IL320763A 2016-04-22 2017-04-20 Solid form of (-)-ambrox produced via bioconversion of homoferon in the presence of a biocatalyst IL320763A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/EP2016/058997 WO2016170106A1 (en) 2015-04-24 2016-04-22 Process for isolating and purifying ambrox
PCT/EP2016/058987 WO2016170099A1 (en) 2015-04-24 2016-04-22 Enzymes and applications thereof
GBGB1618090.3A GB201618090D0 (en) 2016-10-26 2016-10-26 Product
PCT/EP2017/059327 WO2017182542A1 (en) 2016-04-22 2017-04-20 A solid form of (-)-ambrox formed by a bioverversion of homofarnesol in the presence of a biocatalyst

Publications (1)

Publication Number Publication Date
IL320763A true IL320763A (en) 2025-07-01

Family

ID=57738295

Family Applications (5)

Application Number Title Priority Date Filing Date
IL320763A IL320763A (en) 2016-04-22 2017-04-20 Solid form of (-)-ambrox produced via bioconversion of homoferon in the presence of a biocatalyst
IL290606A IL290606B2 (en) 2016-04-22 2017-04-20 A solid form of (–)-ambrox produced by BIOVERVERSION of homoprenzol in the presence of a biocatalyst
IL304330A IL304330B2 (en) 2016-04-22 2017-04-20 A solid form of (-)-ambrox formed by a bioverversion of homofarnesol in the presence of a biocatalyst
IL310388A IL310388B2 (en) 2016-04-22 2017-04-20 Solid form of (-)-ambrox produced via bioconversion of homoferon in the presence of a biocatalyst
IL262393A IL262393B (en) 2016-04-22 2018-10-15 A solid form of (-)-ambrox produced by biooverversion of homoprenzol in the presence of a biocatalyst

Family Applications After (4)

Application Number Title Priority Date Filing Date
IL290606A IL290606B2 (en) 2016-04-22 2017-04-20 A solid form of (–)-ambrox produced by BIOVERVERSION of homoprenzol in the presence of a biocatalyst
IL304330A IL304330B2 (en) 2016-04-22 2017-04-20 A solid form of (-)-ambrox formed by a bioverversion of homofarnesol in the presence of a biocatalyst
IL310388A IL310388B2 (en) 2016-04-22 2017-04-20 Solid form of (-)-ambrox produced via bioconversion of homoferon in the presence of a biocatalyst
IL262393A IL262393B (en) 2016-04-22 2018-10-15 A solid form of (-)-ambrox produced by biooverversion of homoprenzol in the presence of a biocatalyst

Country Status (12)

Country Link
US (5) US10844412B2 (cg-RX-API-DMAC7.html)
EP (1) EP3445755B1 (cg-RX-API-DMAC7.html)
JP (4) JP7407513B2 (cg-RX-API-DMAC7.html)
CN (2) CN109071480B (cg-RX-API-DMAC7.html)
BR (1) BR112018071284A2 (cg-RX-API-DMAC7.html)
CO (1) CO2018011292A2 (cg-RX-API-DMAC7.html)
GB (1) GB201618090D0 (cg-RX-API-DMAC7.html)
IL (5) IL320763A (cg-RX-API-DMAC7.html)
MX (2) MX2018012836A (cg-RX-API-DMAC7.html)
RU (1) RU2018136063A (cg-RX-API-DMAC7.html)
SG (1) SG11201808643SA (cg-RX-API-DMAC7.html)
WO (1) WO2017182542A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201618090D0 (en) * 2016-10-26 2016-12-07 Givaudan Sa Product
GB201917694D0 (en) 2019-12-04 2020-01-15 Givaudan Sa Enzyme mediated process
GB201917688D0 (en) 2019-12-04 2020-01-15 Givaudan Sa SHC enzymes and enzyme variants
GB202011823D0 (en) 2020-07-30 2020-09-16 Givaudan Sa Method
GB202020331D0 (en) * 2020-12-22 2021-02-03 Givaudan Sa Process of making organic compounds
WO2023175123A1 (en) 2022-03-17 2023-09-21 Givaudan Sa Shc enzymes and enzyme variants
WO2024097746A1 (en) * 2022-11-01 2024-05-10 Conagen Inc. Alkene cyclopropanation with nickel catalyst enhancer and improved rearrangement reaction

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4123767C2 (de) * 1991-07-18 1993-11-18 Henkel Kgaa Verfahren zur Herstellung von Stereoisomerengemischen von 8,12-Oxido-13,14,15,16-tetranorlabdan
DE69213916T2 (de) * 1991-12-29 1997-03-06 Kuraray Co Verfahren zur Herstellung von L-Ambrox
DE19649655A1 (de) 1996-11-29 1998-06-04 Haarmann & Reimer Gmbh Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung
US6180121B1 (en) * 1998-03-05 2001-01-30 Colgate-Palmolive Company Fragrance enhancing compositions for cosmetic products
DE19960106A1 (de) 1999-12-14 2001-06-21 Haarmann & Reimer Gmbh Enzyme und Gene für die Herstellung von Vanillin
US20040265850A1 (en) 2002-12-02 2004-12-30 Hua Wang Rapid detection of microorganisms
AU2003302326A1 (en) 2002-12-02 2004-08-10 The Ohio State University Research Foundation Rapid detection of microorganisms
JP4598692B2 (ja) * 2006-02-24 2010-12-15 花王株式会社 新規微生物、当該新規微生物を用いたドデカヒドロ−3a,6,6,9a−テトラメチルナフト[2,1−b]フラン中間体の製造方法
JP4156655B2 (ja) * 2006-07-31 2008-09-24 花王株式会社 (±)−3a、6、6、9a−テトラメチルデカヒドロナフト[2、1−b]フラン−2(1H)−オン類の製造方法
JP5236233B2 (ja) * 2007-09-04 2013-07-17 花王株式会社 (−)−アンブロキサンの製造方法
WO2010139710A1 (de) 2009-06-05 2010-12-09 Basf Se Verbundteile enthaltend plastisch verformbaren polyurethanhartschaumstoff, klebstoff und abdeckmaterial
WO2010139719A2 (de) 2009-06-05 2010-12-09 Basf Se Biokatalytische herstellung von ambroxan
US8935839B2 (en) 2010-02-19 2015-01-20 Owen V. Burt Ballistic enhanced battering ram
ES2925777T3 (es) 2010-11-17 2022-10-19 Basf Se Procedimiento para la ciclación biocatalítica de terpenos y mutantes de ciclasa que pueden usarse en el mismo
US8932839B2 (en) 2010-11-17 2015-01-13 Basf Se Method for the biocatalytic cyclization of terpenes and cyclase mutants employable therein
JP2013132226A (ja) * 2011-12-26 2013-07-08 Kao Corp (−)−3a,6,6,9a−テトラメチルドデカヒドロナフト[2,1−b]フランの製造方法
ES2602190T3 (es) * 2012-04-16 2017-02-20 Basf Se Procedimiento para la preparación de (3E, 7E)-homofarnesol
US20130273619A1 (en) 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol
US9902979B2 (en) 2013-09-05 2018-02-27 Niigata University Method for producing ambrein
GB201318886D0 (en) 2013-10-25 2013-12-11 Givaudan Sa Improvements i or relating to organic compounds
GB201318894D0 (en) * 2013-10-25 2013-12-11 Givaudan Sa Improvements in or relating to organic compounds
GB201507207D0 (en) * 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
GB201507170D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Process
CN105037308B (zh) * 2015-07-06 2017-06-06 四川中烟工业有限责任公司 一种制备降龙涎香醚的方法
MX361536B (es) * 2015-10-23 2018-12-10 Univ Michoacana De San Nicolas De Hidalgo Proceso de sintesis de ambrox a partir de ageratina jocotepecana.
CN105418566B (zh) * 2015-11-27 2018-02-09 北京工商大学 降龙涎醚的一种合成方法
GB201618090D0 (en) * 2016-10-26 2016-12-07 Givaudan Sa Product

Also Published As

Publication number Publication date
JP2019521952A (ja) 2019-08-08
US20210040521A1 (en) 2021-02-11
EP3445755B1 (en) 2026-01-07
EP3445755A1 (en) 2019-02-27
SG11201808643SA (en) 2018-11-29
JP7723048B2 (ja) 2025-08-13
IL262393B (en) 2022-03-01
CN109071480B (zh) 2022-11-29
IL310388B2 (en) 2025-10-01
IL290606B1 (en) 2023-10-01
CO2018011292A2 (es) 2018-11-13
JP2025183197A (ja) 2025-12-16
JP7407513B2 (ja) 2024-01-04
CN109071480A (zh) 2018-12-21
US10844412B2 (en) 2020-11-24
JP7343564B2 (ja) 2023-09-12
US20190136275A1 (en) 2019-05-09
US11773419B2 (en) 2023-10-03
JP2023179438A (ja) 2023-12-19
BR112018071284A2 (pt) 2019-02-12
CN115819385A (zh) 2023-03-21
US20220177935A1 (en) 2022-06-09
IL310388A (en) 2024-03-01
IL304330B2 (en) 2024-07-01
IL310388B1 (en) 2025-06-01
WO2017182542A1 (en) 2017-10-26
CN115819385B (zh) 2025-05-13
RU2018136063A (ru) 2020-05-22
IL262393A (en) 2018-12-31
IL304330A (en) 2023-09-01
JP2022061977A (ja) 2022-04-19
US20230357809A1 (en) 2023-11-09
US20240401094A1 (en) 2024-12-05
MX2023014907A (es) 2024-02-15
US11401541B2 (en) 2022-08-02
MX2018012836A (es) 2019-03-11
RU2018136063A3 (cg-RX-API-DMAC7.html) 2020-07-13
IL290606B2 (en) 2024-02-01
US12084699B2 (en) 2024-09-10
IL290606A (en) 2022-04-01
IL304330B1 (en) 2024-03-01
GB201618090D0 (en) 2016-12-07

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