BR112018014534A2 - A method of preparing and intermediates Tulathromycin - Google Patents

A method of preparing and intermediates Tulathromycin

Info

Publication number
BR112018014534A2
BR112018014534A2 BR112018014534-3A BR112018014534A BR112018014534A2 BR 112018014534 A2 BR112018014534 A2 BR 112018014534A2 BR 112018014534 A BR112018014534 A BR 112018014534A BR 112018014534 A2 BR112018014534 A2 BR 112018014534A2
Authority
BR
Brazil
Prior art keywords
tulathromycin
preparation
formula
organic solvent
purity
Prior art date
Application number
BR112018014534-3A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112018014534B1 (pt
Inventor
Yin Mingxing
Wu Dongdong
Wen Weijiang
Original Assignee
Zhejiang Hisun Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhejiang Hisun Pharmaceutical Co., Ltd. filed Critical Zhejiang Hisun Pharmaceutical Co., Ltd.
Publication of BR112018014534A2 publication Critical patent/BR112018014534A2/zh
Publication of BR112018014534B1 publication Critical patent/BR112018014534B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D315/00—Heterocyclic compounds containing rings having one oxygen atom as the only ring hetero atom according to more than one of groups C07D303/00 - C07D313/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
BR112018014534-3A 2016-01-18 2016-01-18 Método e intermediário para a preparação de tulatromicina BR112018014534B1 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2016/071198 WO2017124222A1 (zh) 2016-01-18 2016-01-18 一种泰拉霉素的制备方法及其中间体

Publications (2)

Publication Number Publication Date
BR112018014534A2 true BR112018014534A2 (zh) 2018-12-11
BR112018014534B1 BR112018014534B1 (pt) 2022-08-23

Family

ID=59361111

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018014534-3A BR112018014534B1 (pt) 2016-01-18 2016-01-18 Método e intermediário para a preparação de tulatromicina

Country Status (6)

Country Link
US (1) US10414746B2 (zh)
EP (1) EP3406619B1 (zh)
CN (1) CN108473524B (zh)
BR (1) BR112018014534B1 (zh)
ES (1) ES2858585T3 (zh)
WO (1) WO2017124222A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107501364B (zh) * 2017-08-29 2019-10-18 博瑞生物医药（苏州）股份有限公司 泰拉菌素中间体的盐
CN110903335A (zh) * 2018-09-14 2020-03-24 广东东阳光药业有限公司 一种泰拉霉素的制备方法
CN111087433B (zh) * 2018-10-23 2023-03-21 湖北美天生物科技股份有限公司 一种泰拉霉素中间体的制备方法
CN109535210A (zh) * 2018-12-19 2019-03-29 江苏威凌生化科技有限公司 一种合成纯化泰拉霉素杂质e的方法
CN109535211B (zh) * 2018-12-19 2020-05-08 江苏威凌生化科技有限公司 一种合成纯化泰拉霉素杂质c的方法
CN111072730B (zh) * 2019-12-16 2021-01-12 浙江国邦药业有限公司 一种泰拉霉素中间体盐的制备方法及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA02007305A (es) * 2000-01-27 2002-11-29 Pfizer Prod Inc Composiciones antiboticas de azalida.
JP4104463B2 (ja) * 2001-04-27 2008-06-18 ファイザー・プロダクツ・インク ４’’−置換された−９−デオキソ−９ａ−アザ−９ａ−ホモエリスロマイシン誘導体を製造するための方法
CN102295672B (zh) 2011-07-13 2014-06-04 武汉回盛生物科技有限公司 一种泰拉菌素的合成方法
CN102260306B (zh) 2011-07-22 2012-07-18 山东鲁抗舍里乐药业有限公司 一种制备泰拉霉素的方法
CN102786569B (zh) * 2012-09-07 2016-12-07 安徽中升药业有限公司 泰拉霉素中间体及其制备方法与泰拉霉素的制备方法
EP3027634B1 (en) * 2013-07-31 2018-03-21 Farma GRS, d.o.o. Process for preparation of tulathromycin
CN103641869B (zh) 2013-12-30 2016-04-06 广州自远生物科技有限公司 一种泰拉菌素的合成方法

Also Published As

Publication number Publication date
ES2858585T3 (es) 2021-09-30
EP3406619A1 (en) 2018-11-28
CN108473524A (zh) 2018-08-31
BR112018014534B1 (pt) 2022-08-23
US20190023681A1 (en) 2019-01-24
WO2017124222A1 (zh) 2017-07-27
CN108473524B (zh) 2021-11-02
US10414746B2 (en) 2019-09-17
EP3406619B1 (en) 2020-11-25
EP3406619A4 (en) 2020-01-01

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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