BR112018010108A2 - micro-organismos para a produção de ferormônios de inseto e compostos relacionados - Google Patents
micro-organismos para a produção de ferormônios de inseto e compostos relacionadosInfo
- Publication number
- BR112018010108A2 BR112018010108A2 BR112018010108A BR112018010108A BR112018010108A2 BR 112018010108 A2 BR112018010108 A2 BR 112018010108A2 BR 112018010108 A BR112018010108 A BR 112018010108A BR 112018010108 A BR112018010108 A BR 112018010108A BR 112018010108 A2 BR112018010108 A2 BR 112018010108A2
- Authority
- BR
- Brazil
- Prior art keywords
- aldehydes
- acetates
- recombinant microorganisms
- fatty alcohols
- production
- Prior art date
Links
- 244000005700 microbiome Species 0.000 title abstract 5
- 239000003016 pheromone Substances 0.000 title abstract 4
- 241000238631 Hexapoda Species 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 150000001242 acetic acid derivatives Chemical class 0.000 abstract 4
- 150000001299 aldehydes Chemical class 0.000 abstract 4
- 150000002191 fatty alcohols Chemical class 0.000 abstract 2
- 230000037361 pathway Effects 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000019634 flavors Nutrition 0.000 abstract 1
- 239000003205 fragrance Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000005649 metathesis reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/02—Acyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/0105—Long-chain-fatty-acyl-CoA reductase (1.2.1.50)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/19—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
- C12Y114/19001—Stearoyl-CoA 9-desaturase (1.14.19.1), i.e. DELTA9-desaturase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/19—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
- C12Y114/19005—DELTA11-fatty-acid desaturase (1.14.19.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Enzymes And Modification Thereof (AREA)
- Insects & Arthropods (AREA)
- Mycology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562257054P | 2015-11-18 | 2015-11-18 | |
| US201662351605P | 2016-06-17 | 2016-06-17 | |
| PCT/US2016/062852 WO2017087846A1 (en) | 2015-11-18 | 2016-11-18 | Microorganisms for the production of insect pheromones and related compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112018010108A2 true BR112018010108A2 (pt) | 2018-11-21 |
Family
ID=58717924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018010108A BR112018010108A2 (pt) | 2015-11-18 | 2016-11-18 | micro-organismos para a produção de ferormônios de inseto e compostos relacionados |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US10308962B1 (https=) |
| EP (2) | EP3376859B1 (https=) |
| JP (1) | JP6737885B2 (https=) |
| CN (1) | CN108697072A (https=) |
| BR (1) | BR112018010108A2 (https=) |
| DK (1) | DK3376859T3 (https=) |
| ES (1) | ES2864102T3 (https=) |
| HU (1) | HUE053613T2 (https=) |
| WO (1) | WO2017087846A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102014220186B4 (de) * | 2013-12-12 | 2017-06-22 | Technische Universität Dresden | Hefestämme und Verfahren zur Produktion von Omega-Hydroxyfettsäuren und Dicarbonsäuren |
| CN108138202B (zh) | 2015-06-26 | 2023-05-16 | 丹麦科技大学 | 用于在酵母中产生蛾信息素的方法 |
| EP3376859B1 (en) | 2015-11-18 | 2021-01-06 | Provivi, Inc. | Microorganisms for the production of insect pheromones and related compounds |
| WO2017214133A2 (en) | 2016-06-06 | 2017-12-14 | Provivi, Inc. | Semi-biosynthetic production of fatty alcohols and fatty aldehydes |
| US11434506B2 (en) | 2016-12-16 | 2022-09-06 | Danmarks Tekniske Universitet | Production of desaturated fatty alcohols and desaturated fatty alcohol acetates in yeast |
| ES2888232T3 (es) * | 2016-12-16 | 2022-01-03 | Univ Danmarks Tekniske | Procedimientos para la producción de alcoholes grasos y sus derivados en levadura |
| MX382401B (es) | 2017-05-17 | 2025-03-13 | Provivi Inc | Microorganismos para la producción de feromonas de insectos y compuestos relacionados. |
| EP3521439A1 (en) * | 2018-01-31 | 2019-08-07 | Commissariat à l'Energie Atomique et aux Energies Alternatives | Method for the production of triacylglycerides and fatty acids |
| US11220675B2 (en) * | 2018-05-02 | 2022-01-11 | Provivi, Inc. | Multi-substrate metabolism for improving biomass and lipid production |
| CN109699646B (zh) * | 2018-12-29 | 2020-12-15 | 云南大学 | 一种水稻螟虫信息素成分的制备方法 |
| EP3766982A1 (en) | 2019-07-18 | 2021-01-20 | Delft Advanced Biofuels B.V. | Integrated system for biocatalytically producing and recovering an organic substance |
| CN111296498A (zh) * | 2020-03-31 | 2020-06-19 | 夏书好 | 多功能中草药烟熏消毒组合物 |
| WO2021262906A1 (en) * | 2020-06-23 | 2021-12-30 | Provivi, Inc. | Synthesis of complex insect pheromone blends and reaction apparatuses for the same |
| CN112425609A (zh) * | 2020-12-18 | 2021-03-02 | 重庆谷百奥生物研究院有限公司 | 一种促进香蕉植株生长和防治香蕉枯萎病的绿僵菌制剂 |
| US20240229086A1 (en) * | 2021-03-29 | 2024-07-11 | Genomatica, Inc. | Production Of Non-Native Monounsaturated Fatty Acids In Bacteria |
| MX2024005812A (es) * | 2021-11-12 | 2024-05-28 | Isca Tech Inc | Metodos de produccion de feromonas insaturadas dobles utilizando rutas metabolicas. |
| US20240287553A1 (en) * | 2022-01-31 | 2024-08-29 | Isca Technologies, Inc. | Methods of Production of Double Unsaturated Pheromones Using Metabolic Pathways |
| US20230242945A1 (en) * | 2022-01-31 | 2023-08-03 | Isca Technologies, Inc. | Methods for production of amyelois transitella pheromone precursor |
| US20230242944A1 (en) * | 2022-01-31 | 2023-08-03 | Isca Technologies, Inc. | Methods for production of diatraea saccharalis pheromone precursors |
| JP7672362B2 (ja) * | 2022-06-03 | 2025-05-07 | 信越化学工業株式会社 | （４ｚ，６ｅ）－４，６－ウンデカジエニル＝トリメチルアセテート、及びそれからの（５ｚ，７ｅ）－５，７－ドデカジエン化合物の製造方法 |
| CN115452991B (zh) * | 2022-09-15 | 2024-07-12 | 江苏科技大学 | 十四碳烯酸和十六碳烯醛在检测检疫性害虫中的应用 |
| CN115725619B (zh) * | 2022-10-31 | 2024-04-02 | 西南大学 | 家蚕脂肪酶基因BmTGLc的应用及方法 |
| WO2025046624A1 (en) * | 2023-08-29 | 2025-03-06 | Pheromones Biotech Llp | A method for mating disruption of insects pests using semiochemicals |
| CN118955670B (zh) * | 2024-10-17 | 2025-04-18 | 湘湖实验室(农业浙江省实验室) | 用于合成十八碳烯类化合物的蛋白及合成十八碳烯类化合物的方法 |
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| US4427595A (en) | 1981-07-16 | 1984-01-24 | Massachusetts Institute Of Technology | Catalyst composition to effect metathesis of acetylenes |
| JPS61254193A (ja) | 1985-05-07 | 1986-11-11 | Harima Chem Inc | 不飽和ワツクスエステルの製造方法 |
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| DE3724254A1 (de) | 1987-07-22 | 1989-02-02 | Henkel Kgaa | Verfahren zur hydrierung von fettsaeuremethylestern im druckbereich von 20 bis 100 bar |
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2016
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- 2016-11-18 CN CN201680079219.2A patent/CN108697072A/zh active Pending
- 2016-11-18 JP JP2018525739A patent/JP6737885B2/ja active Active
- 2016-11-18 EP EP20216824.1A patent/EP3868890A1/en active Pending
- 2016-11-18 DK DK16867255.8T patent/DK3376859T3/da active
- 2016-11-18 BR BR112018010108A patent/BR112018010108A2/pt not_active Application Discontinuation
- 2016-11-18 ES ES16867255T patent/ES2864102T3/es active Active
- 2016-11-18 WO PCT/US2016/062852 patent/WO2017087846A1/en not_active Ceased
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2018
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- 2019-05-23 US US16/420,566 patent/US11109596B2/en active Active
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| DK3376859T3 (da) | 2021-03-29 |
| EP3376859B1 (en) | 2021-01-06 |
| US10308962B1 (en) | 2019-06-04 |
| US20190338317A1 (en) | 2019-11-07 |
| US11109596B2 (en) | 2021-09-07 |
| WO2017087846A1 (en) | 2017-05-26 |
| JP2019503657A (ja) | 2019-02-14 |
| EP3376859A1 (en) | 2018-09-26 |
| HUE053613T2 (hu) | 2021-07-28 |
| ES2864102T3 (es) | 2021-10-13 |
| EP3376859A4 (en) | 2019-03-06 |
| EP3868890A1 (en) | 2021-08-25 |
| JP6737885B2 (ja) | 2020-08-12 |
| US11844353B2 (en) | 2023-12-19 |
| US20220053774A1 (en) | 2022-02-24 |
| CN108697072A (zh) | 2018-10-23 |
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