BR112017023374A2 - formulação de anticorpo anti-cgrp - Google Patents

formulação de anticorpo anti-cgrp

Info

Publication number
BR112017023374A2
BR112017023374A2 BR112017023374-6A BR112017023374A BR112017023374A2 BR 112017023374 A2 BR112017023374 A2 BR 112017023374A2 BR 112017023374 A BR112017023374 A BR 112017023374A BR 112017023374 A2 BR112017023374 A2 BR 112017023374A2
Authority
BR
Brazil
Prior art keywords
antibody formulation
cgrp antibody
headaches
occasional
chronic
Prior art date
Application number
BR112017023374-6A
Other languages
English (en)
Inventor
N. SHARMA Anant
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BR112017023374A2 publication Critical patent/BR112017023374A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Abstract

a presente invenção refere-se às formulações farmacêuticas para anticorpos anti-cgrp, e métodos de usar as mesmas, que são úteis como tratamento para enxaquecas, cefaleias ocasionais, cefaleias crônicas, cefaleias em salvas crônicas, e cefaleias em salvas ocasionais.
BR112017023374-6A 2015-06-17 2016-06-08 formulação de anticorpo anti-cgrp BR112017023374A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562180905P 2015-06-17 2015-06-17
US62/180,905 2015-06-17
PCT/US2016/036407 WO2016205037A1 (en) 2015-06-17 2016-06-08 Anti-cgrp antibody formulation

Publications (1)

Publication Number Publication Date
BR112017023374A2 true BR112017023374A2 (pt) 2018-07-24

Family

ID=56131672

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017023374-6A BR112017023374A2 (pt) 2015-06-17 2016-06-08 formulação de anticorpo anti-cgrp

Country Status (21)

Country Link
US (3) US11498959B2 (pt)
EP (1) EP3310809A1 (pt)
JP (1) JP6438599B2 (pt)
KR (1) KR102000867B1 (pt)
CN (2) CN107787229A (pt)
AR (1) AR104847A1 (pt)
AU (1) AU2016280555B2 (pt)
BR (1) BR112017023374A2 (pt)
CA (1) CA2984185A1 (pt)
EA (1) EA037580B1 (pt)
HK (1) HK1245813A1 (pt)
IL (2) IL292562A (pt)
JO (1) JO3772B1 (pt)
MA (1) MA49726A (pt)
MX (1) MX2017016199A (pt)
MY (1) MY184266A (pt)
NZ (1) NZ737046A (pt)
TW (1) TWI725973B (pt)
UA (1) UA120881C2 (pt)
WO (1) WO2016205037A1 (pt)
ZA (1) ZA201707324B (pt)

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US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
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KR20210113597A (ko) 2019-01-08 2021-09-16 하. 룬드벡 아크티에셀스카브 항-cgrp 항체를 사용한 두통의 급성 치료 및 신속 치료
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Also Published As

Publication number Publication date
CN114948847A (zh) 2022-08-30
KR20180002858A (ko) 2018-01-08
AR104847A1 (es) 2017-08-16
CN107787229A (zh) 2018-03-09
TW201711697A (zh) 2017-04-01
IL255443A0 (en) 2017-12-31
US11498959B2 (en) 2022-11-15
MA49726A (fr) 2020-06-10
WO2016205037A1 (en) 2016-12-22
AU2016280555B2 (en) 2018-11-15
US20220112277A1 (en) 2022-04-14
EP3310809A1 (en) 2018-04-25
MX2017016199A (es) 2018-03-01
IL255443B (en) 2022-06-01
MY184266A (en) 2021-03-30
EA037580B1 (ru) 2021-04-16
ZA201707324B (en) 2020-01-29
JO3772B1 (ar) 2021-01-31
JP6438599B2 (ja) 2018-12-19
EA201792359A1 (ru) 2018-05-31
IL292562A (en) 2022-06-01
JP2018517727A (ja) 2018-07-05
UA120881C2 (uk) 2020-02-25
AU2016280555A1 (en) 2017-11-16
US20180134772A1 (en) 2018-05-17
TWI725973B (zh) 2021-05-01
HK1245813A1 (zh) 2018-08-31
KR102000867B1 (ko) 2019-07-16
NZ737046A (en) 2019-09-27
CA2984185A1 (en) 2016-12-22
US20230159628A1 (en) 2023-05-25

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]