CO2017005566A2 - Péptidos cíclicos derivados de cd44v6 para el tratamiento de enfermedades relacionadas con cánceres y angiogénesis - Google Patents

Péptidos cíclicos derivados de cd44v6 para el tratamiento de enfermedades relacionadas con cánceres y angiogénesis

Info

Publication number
CO2017005566A2
CO2017005566A2 CONC2017/0005566A CO2017005566A CO2017005566A2 CO 2017005566 A2 CO2017005566 A2 CO 2017005566A2 CO 2017005566 A CO2017005566 A CO 2017005566A CO 2017005566 A2 CO2017005566 A2 CO 2017005566A2
Authority
CO
Colombia
Prior art keywords
angiogenesis
treatment
cd44v6
cancers
diseases related
Prior art date
Application number
CONC2017/0005566A
Other languages
English (en)
Inventor
Alexandra Matzke-Ogi
Véronique Orian-Rousseau
Uwe Haberkorn
Thomas Lindner
Walter Mier
Original Assignee
Amcure Gmbh
Ruprecht Karls Univ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52425505&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO2017005566(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amcure Gmbh, Ruprecht Karls Univ filed Critical Amcure Gmbh
Publication of CO2017005566A2 publication Critical patent/CO2017005566A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70585—CD44
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

RESUMEN La presente invención se refiere a compuestos, composiciones farmacéuticas y métodos para el tratamiento de diferentes formas de enfermedades relacionadas con el cáncer y angiogénesis usando péptidos cíclicos.
CONC2017/0005566A 2014-12-05 2017-06-05 Péptidos cíclicos derivados de cd44v6 para el tratamiento de enfermedades relacionadas con cánceres y angiogénesis CO2017005566A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1421647.7A GB201421647D0 (en) 2014-12-05 2014-12-05 CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
PCT/EP2015/078892 WO2016087680A1 (en) 2014-12-05 2015-12-07 Cd44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases

Publications (1)

Publication Number Publication Date
CO2017005566A2 true CO2017005566A2 (es) 2017-08-31

Family

ID=52425505

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2017/0005566A CO2017005566A2 (es) 2014-12-05 2017-06-05 Péptidos cíclicos derivados de cd44v6 para el tratamiento de enfermedades relacionadas con cánceres y angiogénesis

Country Status (17)

Country Link
US (2) US10703796B2 (es)
EP (1) EP3227322B1 (es)
JP (2) JP2018506508A (es)
KR (1) KR20170086124A (es)
CN (1) CN107207578B (es)
AU (1) AU2015356997B2 (es)
BR (1) BR112017011543A2 (es)
CA (1) CA2968333A1 (es)
CL (1) CL2017001310A1 (es)
CO (1) CO2017005566A2 (es)
EA (1) EA035767B1 (es)
GB (1) GB201421647D0 (es)
IL (1) IL252626B (es)
MX (1) MX2017007338A (es)
PH (1) PH12017500853A1 (es)
SG (1) SG11201703825UA (es)
WO (1) WO2016087680A1 (es)

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US10441654B2 (en) 2014-01-24 2019-10-15 Children's Hospital Of Eastern Ontario Research Institute Inc. SMC combination therapy for the treatment of cancer
TWI663983B (zh) 2014-02-04 2019-07-01 美商輝瑞大藥廠 用於治療癌症之ｐｄ－１拮抗劑及ｖｅｇｆｒ抑制劑之組合
WO2016137985A1 (en) 2015-02-26 2016-09-01 Merck Patent Gmbh Pd-1 / pd-l1 inhibitors for the treatment of cancer
MX2017016324A (es) 2015-06-16 2018-03-02 Merck Patent Gmbh Tratamientos de combinacion de antagonista de ligando 1 de muerte programada (pd-l1).
BR112019006504A2 (pt) 2016-10-06 2019-06-25 Merck Patent Gmbh regime de dosagem de avelumabe para o tratamento de câncer
US20190388407A1 (en) * 2017-02-12 2019-12-26 Aiviva Biopharma, Inc. Multikinase inhibitors of vegf and tfg beta and uses thereof
CN111053771A (zh) * 2018-10-16 2020-04-24 正大天晴药业集团股份有限公司 用于治疗食道鳞状细胞癌的喹啉类化合物或其药学上可接受的盐

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EP1417974A1 (en) 2002-11-08 2004-05-12 Boehringer Ingelheim International GmbH Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and radiotherapy
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Also Published As

Publication number Publication date
EA201791249A1 (ru) 2017-11-30
JP6952843B2 (ja) 2021-10-27
US10703796B2 (en) 2020-07-07
WO2016087680A1 (en) 2016-06-09
EA035767B1 (ru) 2020-08-07
CN107207578B (zh) 2021-10-22
EP3227322A1 (en) 2017-10-11
IL252626B (en) 2022-01-01
GB201421647D0 (en) 2015-01-21
MX2017007338A (es) 2018-04-11
US20200283503A1 (en) 2020-09-10
AU2015356997A1 (en) 2017-06-29
SG11201703825UA (en) 2017-07-28
KR20170086124A (ko) 2017-07-25
BR112017011543A2 (pt) 2018-07-10
EP3227322B1 (en) 2024-04-10
AU2015356997B2 (en) 2020-06-25
US20170320930A1 (en) 2017-11-09
IL252626A0 (en) 2017-07-31
PH12017500853A1 (en) 2017-11-06
CN107207578A (zh) 2017-09-26
JP2020183441A (ja) 2020-11-12
CA2968333A1 (en) 2016-06-09
CL2017001310A1 (es) 2018-02-02
JP2018506508A (ja) 2018-03-08

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