BR112017006848A2 - composições. - Google Patents
composições.Info
- Publication number
- BR112017006848A2 BR112017006848A2 BR112017006848A BR112017006848A BR112017006848A2 BR 112017006848 A2 BR112017006848 A2 BR 112017006848A2 BR 112017006848 A BR112017006848 A BR 112017006848A BR 112017006848 A BR112017006848 A BR 112017006848A BR 112017006848 A2 BR112017006848 A2 BR 112017006848A2
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- aqueous solution
- furthermore
- relates
- therapeutic use
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
a invenção se refere a uma solução aquosa que compreende entre 80 mg a/ml e 400 mg a/ml de uma polimixina sulfometilada e um cartucho contendo a mesma. além disso, a invenção apresenta uma solução aquosa de uso terapêutico.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462059711P | 2014-10-03 | 2014-10-03 | |
US62/059,711 | 2014-10-03 | ||
PCT/EP2015/072728 WO2016050928A1 (en) | 2014-10-03 | 2015-10-01 | Compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112017006848A2 true BR112017006848A2 (pt) | 2017-12-12 |
BR112017006848B1 BR112017006848B1 (pt) | 2022-10-04 |
Family
ID=54252294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017006848-6A BR112017006848B1 (pt) | 2014-10-03 | 2015-10-01 | Composições |
Country Status (25)
Country | Link |
---|---|
US (1) | US10532080B2 (pt) |
EP (2) | EP3718571A1 (pt) |
JP (1) | JP6633061B2 (pt) |
KR (1) | KR102433278B1 (pt) |
CN (1) | CN106794221B (pt) |
AU (1) | AU2015326842B2 (pt) |
BR (1) | BR112017006848B1 (pt) |
CA (1) | CA2961700C (pt) |
CO (1) | CO2017004303A2 (pt) |
DK (1) | DK3200827T3 (pt) |
ES (1) | ES2822943T3 (pt) |
HR (1) | HRP20201598T1 (pt) |
HU (1) | HUE052028T2 (pt) |
IL (1) | IL251479B (pt) |
MX (1) | MX2017004176A (pt) |
PH (1) | PH12017500516A1 (pt) |
PL (1) | PL3200827T3 (pt) |
PT (1) | PT3200827T (pt) |
RS (1) | RS60874B1 (pt) |
RU (1) | RU2712276C2 (pt) |
SG (1) | SG11201702717XA (pt) |
SI (1) | SI3200827T1 (pt) |
UA (1) | UA119573C2 (pt) |
WO (1) | WO2016050928A1 (pt) |
ZA (1) | ZA201702047B (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI2943503T1 (sl) | 2013-01-11 | 2017-11-30 | Xellia Pharmaceuticals Aps | Polimiksini, sestava, postopki priprave in postopki uporabe |
KR20170032348A (ko) | 2014-07-09 | 2017-03-22 | 셀리아 파마슈티칼즈 에이피에스 | 저 치환된 폴리믹신 및 이의 조성물 |
JP6626890B2 (ja) * | 2014-10-03 | 2019-12-25 | クセリア ファーマシューティカルズ エーピーエスXellia Pharmaceuticals ApS | 吸入用デバイスおよび同デバイスに含有される水溶液 |
CN112546030A (zh) * | 2019-09-26 | 2021-03-26 | 盈科瑞(天津)创新医药研究有限公司 | 一种吸入用多粘菌素e甲磺酸钠溶液及其制备方法 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1062895A (en) | 1962-12-13 | 1967-03-22 | Wellcome Found | Sulphomethyl derivatives of polymxin |
DE1906699A1 (de) | 1968-02-12 | 1970-02-05 | Pfizer | Neue Polymyxinderivate und Verfahren zu deren Herstellung |
FR1586834A (pt) | 1968-02-12 | 1970-03-06 | ||
WO1989009626A1 (en) | 1988-04-07 | 1989-10-19 | Luther Ronald B | Non-thrombogenic intravascular time release catheter |
ATE111746T1 (de) * | 1989-11-15 | 1994-10-15 | Sandoz Ag | Polymyxinkonjugate. |
EP0804088B1 (en) * | 1994-06-29 | 2000-10-25 | Meiji Seika Kaisha Ltd. | Stabilized composition comprising colistin sulfate |
WO1998020836A2 (en) * | 1996-11-15 | 1998-05-22 | Pathogenesis Corporation | Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections |
US5767068A (en) | 1997-02-13 | 1998-06-16 | Pathogenesis Corporation | Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections |
CA2447600C (en) | 2001-05-18 | 2015-10-20 | Chiron Corporation | Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics |
US20040022740A1 (en) | 2001-07-10 | 2004-02-05 | Baker William R. | Macrolide formulations for inhalation and methods of treatment of endobronchial infections |
EP1340506B1 (en) | 2002-03-01 | 2006-12-27 | CHIESI FARMACEUTICI S.p.A. | Compositions comprising pulmonary surfactants and a polymyxin having improved surface properties |
WO2008025560A1 (en) * | 2006-09-01 | 2008-03-06 | Pari Pharma Gmbh | Methods for taste masking of nebulised compositions for nasal and pulmonary inhalation therapy |
US20080066739A1 (en) | 2006-09-20 | 2008-03-20 | Lemahieu Edward | Methods and systems of delivering medication via inhalation |
US8329645B2 (en) | 2008-02-08 | 2012-12-11 | Northern Antibiotics Ltd. | Polymyxin derivatives and uses thereof |
EP2470555B1 (en) | 2009-10-30 | 2014-12-24 | Xellia Pharmaceuticals ApS | Method for purification of colistin and purified colistin components |
CN102190711A (zh) * | 2010-01-22 | 2011-09-21 | 上海医药工业研究院 | 多黏菌素e组合物及其制备方法和用途 |
GB201010500D0 (en) | 2010-06-23 | 2010-08-04 | Univ Cardiff | Therapeutic conjugates |
WO2012168820A1 (en) | 2011-06-08 | 2012-12-13 | Pfizer Inc. | Polymyxin derivatives useful as antibacterial agents |
CN102531955B (zh) | 2011-09-16 | 2014-02-19 | 浙江众益制药股份有限公司 | 奥沙拉秦钠的制备方法和甲磺化反应的后处理方法 |
SI2943503T1 (sl) | 2013-01-11 | 2017-11-30 | Xellia Pharmaceuticals Aps | Polimiksini, sestava, postopki priprave in postopki uporabe |
TW201522364A (zh) | 2013-06-07 | 2015-06-16 | Xellia Pharmaceuticals Aps | 黏菌素甲磺酸鈉(cms)之定性方法 |
KR20170032348A (ko) | 2014-07-09 | 2017-03-22 | 셀리아 파마슈티칼즈 에이피에스 | 저 치환된 폴리믹신 및 이의 조성물 |
JP6626890B2 (ja) | 2014-10-03 | 2019-12-25 | クセリア ファーマシューティカルズ エーピーエスXellia Pharmaceuticals ApS | 吸入用デバイスおよび同デバイスに含有される水溶液 |
-
2015
- 2015-10-01 JP JP2017517047A patent/JP6633061B2/ja active Active
- 2015-10-01 EP EP20176607.8A patent/EP3718571A1/en not_active Withdrawn
- 2015-10-01 US US15/516,243 patent/US10532080B2/en active Active
- 2015-10-01 EP EP15775173.6A patent/EP3200827B1/en active Active
- 2015-10-01 BR BR112017006848-6A patent/BR112017006848B1/pt active IP Right Grant
- 2015-10-01 CN CN201580053905.8A patent/CN106794221B/zh active Active
- 2015-10-01 PL PL15775173T patent/PL3200827T3/pl unknown
- 2015-10-01 HU HUE15775173A patent/HUE052028T2/hu unknown
- 2015-10-01 SI SI201531386T patent/SI3200827T1/sl unknown
- 2015-10-01 MX MX2017004176A patent/MX2017004176A/es active IP Right Grant
- 2015-10-01 PT PT157751736T patent/PT3200827T/pt unknown
- 2015-10-01 RS RS20201176A patent/RS60874B1/sr unknown
- 2015-10-01 WO PCT/EP2015/072728 patent/WO2016050928A1/en active Application Filing
- 2015-10-01 ES ES15775173T patent/ES2822943T3/es active Active
- 2015-10-01 CA CA2961700A patent/CA2961700C/en active Active
- 2015-10-01 KR KR1020177011539A patent/KR102433278B1/ko active IP Right Grant
- 2015-10-01 UA UAA201704127A patent/UA119573C2/uk unknown
- 2015-10-01 DK DK15775173.6T patent/DK3200827T3/da active
- 2015-10-01 AU AU2015326842A patent/AU2015326842B2/en active Active
- 2015-10-01 SG SG11201702717XA patent/SG11201702717XA/en unknown
- 2015-10-01 RU RU2017114136A patent/RU2712276C2/ru active
-
2017
- 2017-03-17 PH PH12017500516A patent/PH12017500516A1/en unknown
- 2017-03-23 ZA ZA2017/02047A patent/ZA201702047B/en unknown
- 2017-03-30 IL IL251479A patent/IL251479B/en active IP Right Grant
- 2017-04-28 CO CONC2017/0004303A patent/CO2017004303A2/es unknown
-
2020
- 2020-10-07 HR HRP20201598TT patent/HRP20201598T1/hr unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 01/10/2015, OBSERVADAS AS CONDICOES LEGAIS |