BR112017006848A2 - composições. - Google Patents

composições.

Info

Publication number
BR112017006848A2
BR112017006848A2 BR112017006848A BR112017006848A BR112017006848A2 BR 112017006848 A2 BR112017006848 A2 BR 112017006848A2 BR 112017006848 A BR112017006848 A BR 112017006848A BR 112017006848 A BR112017006848 A BR 112017006848A BR 112017006848 A2 BR112017006848 A2 BR 112017006848A2
Authority
BR
Brazil
Prior art keywords
compositions
aqueous solution
furthermore
relates
therapeutic use
Prior art date
Application number
BR112017006848A
Other languages
English (en)
Other versions
BR112017006848B1 (pt
Inventor
Bencic Nenad
Original Assignee
Xellia Pharmaceuticals Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54252294&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112017006848(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xellia Pharmaceuticals Aps filed Critical Xellia Pharmaceuticals Aps
Publication of BR112017006848A2 publication Critical patent/BR112017006848A2/pt
Publication of BR112017006848B1 publication Critical patent/BR112017006848B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

a invenção se refere a uma solução aquosa que compreende entre 80 mg a/ml e 400 mg a/ml de uma polimixina sulfometilada e um cartucho contendo a mesma. além disso, a invenção apresenta uma solução aquosa de uso terapêutico.
BR112017006848-6A 2014-10-03 2015-10-01 Composições BR112017006848B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462059711P 2014-10-03 2014-10-03
US62/059,711 2014-10-03
PCT/EP2015/072728 WO2016050928A1 (en) 2014-10-03 2015-10-01 Compositions

Publications (2)

Publication Number Publication Date
BR112017006848A2 true BR112017006848A2 (pt) 2017-12-12
BR112017006848B1 BR112017006848B1 (pt) 2022-10-04

Family

ID=54252294

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017006848-6A BR112017006848B1 (pt) 2014-10-03 2015-10-01 Composições

Country Status (25)

Country Link
US (1) US10532080B2 (pt)
EP (2) EP3718571A1 (pt)
JP (1) JP6633061B2 (pt)
KR (1) KR102433278B1 (pt)
CN (1) CN106794221B (pt)
AU (1) AU2015326842B2 (pt)
BR (1) BR112017006848B1 (pt)
CA (1) CA2961700C (pt)
CO (1) CO2017004303A2 (pt)
DK (1) DK3200827T3 (pt)
ES (1) ES2822943T3 (pt)
HR (1) HRP20201598T1 (pt)
HU (1) HUE052028T2 (pt)
IL (1) IL251479B (pt)
MX (1) MX2017004176A (pt)
PH (1) PH12017500516A1 (pt)
PL (1) PL3200827T3 (pt)
PT (1) PT3200827T (pt)
RS (1) RS60874B1 (pt)
RU (1) RU2712276C2 (pt)
SG (1) SG11201702717XA (pt)
SI (1) SI3200827T1 (pt)
UA (1) UA119573C2 (pt)
WO (1) WO2016050928A1 (pt)
ZA (1) ZA201702047B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2943503T1 (sl) 2013-01-11 2017-11-30 Xellia Pharmaceuticals Aps Polimiksini, sestava, postopki priprave in postopki uporabe
KR20170032348A (ko) 2014-07-09 2017-03-22 셀리아 파마슈티칼즈 에이피에스 저 치환된 폴리믹신 및 이의 조성물
JP6626890B2 (ja) * 2014-10-03 2019-12-25 クセリア ファーマシューティカルズ エーピーエスXellia Pharmaceuticals ApS 吸入用デバイスおよび同デバイスに含有される水溶液
CN112546030A (zh) * 2019-09-26 2021-03-26 盈科瑞(天津)创新医药研究有限公司 一种吸入用多粘菌素e甲磺酸钠溶液及其制备方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1062895A (en) 1962-12-13 1967-03-22 Wellcome Found Sulphomethyl derivatives of polymxin
DE1906699A1 (de) 1968-02-12 1970-02-05 Pfizer Neue Polymyxinderivate und Verfahren zu deren Herstellung
FR1586834A (pt) 1968-02-12 1970-03-06
WO1989009626A1 (en) 1988-04-07 1989-10-19 Luther Ronald B Non-thrombogenic intravascular time release catheter
ATE111746T1 (de) * 1989-11-15 1994-10-15 Sandoz Ag Polymyxinkonjugate.
EP0804088B1 (en) * 1994-06-29 2000-10-25 Meiji Seika Kaisha Ltd. Stabilized composition comprising colistin sulfate
WO1998020836A2 (en) * 1996-11-15 1998-05-22 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
US5767068A (en) 1997-02-13 1998-06-16 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
CA2447600C (en) 2001-05-18 2015-10-20 Chiron Corporation Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics
US20040022740A1 (en) 2001-07-10 2004-02-05 Baker William R. Macrolide formulations for inhalation and methods of treatment of endobronchial infections
EP1340506B1 (en) 2002-03-01 2006-12-27 CHIESI FARMACEUTICI S.p.A. Compositions comprising pulmonary surfactants and a polymyxin having improved surface properties
WO2008025560A1 (en) * 2006-09-01 2008-03-06 Pari Pharma Gmbh Methods for taste masking of nebulised compositions for nasal and pulmonary inhalation therapy
US20080066739A1 (en) 2006-09-20 2008-03-20 Lemahieu Edward Methods and systems of delivering medication via inhalation
US8329645B2 (en) 2008-02-08 2012-12-11 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
EP2470555B1 (en) 2009-10-30 2014-12-24 Xellia Pharmaceuticals ApS Method for purification of colistin and purified colistin components
CN102190711A (zh) * 2010-01-22 2011-09-21 上海医药工业研究院 多黏菌素e组合物及其制备方法和用途
GB201010500D0 (en) 2010-06-23 2010-08-04 Univ Cardiff Therapeutic conjugates
WO2012168820A1 (en) 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
CN102531955B (zh) 2011-09-16 2014-02-19 浙江众益制药股份有限公司 奥沙拉秦钠的制备方法和甲磺化反应的后处理方法
SI2943503T1 (sl) 2013-01-11 2017-11-30 Xellia Pharmaceuticals Aps Polimiksini, sestava, postopki priprave in postopki uporabe
TW201522364A (zh) 2013-06-07 2015-06-16 Xellia Pharmaceuticals Aps 黏菌素甲磺酸鈉(cms)之定性方法
KR20170032348A (ko) 2014-07-09 2017-03-22 셀리아 파마슈티칼즈 에이피에스 저 치환된 폴리믹신 및 이의 조성물
JP6626890B2 (ja) 2014-10-03 2019-12-25 クセリア ファーマシューティカルズ エーピーエスXellia Pharmaceuticals ApS 吸入用デバイスおよび同デバイスに含有される水溶液

Also Published As

Publication number Publication date
US20170239321A1 (en) 2017-08-24
EP3200827B1 (en) 2020-08-12
EP3718571A1 (en) 2020-10-07
ZA201702047B (en) 2018-08-29
CA2961700C (en) 2023-03-07
PH12017500516A1 (en) 2017-08-07
RU2017114136A (ru) 2018-11-06
DK3200827T3 (da) 2020-10-12
WO2016050928A1 (en) 2016-04-07
AU2015326842B2 (en) 2018-11-08
PL3200827T3 (pl) 2020-12-14
CA2961700A1 (en) 2016-04-07
KR20170067801A (ko) 2017-06-16
JP6633061B2 (ja) 2020-01-22
BR112017006848B1 (pt) 2022-10-04
CO2017004303A2 (es) 2017-07-28
SI3200827T1 (sl) 2020-11-30
ES2822943T3 (es) 2021-05-05
EP3200827A1 (en) 2017-08-09
JP2017534597A (ja) 2017-11-24
KR102433278B1 (ko) 2022-08-16
PT3200827T (pt) 2020-10-08
MX2017004176A (es) 2017-08-28
RU2712276C2 (ru) 2020-01-28
HUE052028T2 (hu) 2021-04-28
RU2017114136A3 (pt) 2019-04-18
CN106794221B (zh) 2021-12-10
SG11201702717XA (en) 2017-04-27
RS60874B1 (sr) 2020-11-30
CN106794221A (zh) 2017-05-31
UA119573C2 (uk) 2019-07-10
IL251479B (en) 2020-11-30
US10532080B2 (en) 2020-01-14
IL251479A0 (en) 2017-05-29
AU2015326842A1 (en) 2017-04-13
HRP20201598T1 (hr) 2021-02-19

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 01/10/2015, OBSERVADAS AS CONDICOES LEGAIS