CN102531955B - 奥沙拉秦钠的制备方法和甲磺化反应的后处理方法 - Google Patents
奥沙拉秦钠的制备方法和甲磺化反应的后处理方法 Download PDFInfo
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- CN102531955B CN102531955B CN201110276145.0A CN201110276145A CN102531955B CN 102531955 B CN102531955 B CN 102531955B CN 201110276145 A CN201110276145 A CN 201110276145A CN 102531955 B CN102531955 B CN 102531955B
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编号 | 碎冰倍数 | 收率 | 熔点 |
对比例3 | 1 | 60.5% | 54.2~56.2℃ |
对比例4 | 2 | 73.8% | 53.5~55.7℃ |
对比例5 | 5 | 76.1% | 51.5~53.8℃ |
编号 | 水倍数 | 水温度 | 收率 | 熔点 |
对比例6 | 2 | 20℃ | 无 | 无 |
对比例7 | 5 | 20℃ | 无 | 无 |
对比例8 | 5 | 10℃ | 13% | 57.0~58.8℃ |
对比例9 | 2 | 10℃ | 无 | 无 |
对比例10 | 5 | 0℃ | 39% | 56.7~57.9℃ |
对比例11 | 2 | 0℃ | 21% | 57.2~58.9℃ |
对比例12 | 1 | 0℃ | 15% | 57.5~59.1℃ |
Claims (13)
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CN201110276145.0A CN102531955B (zh) | 2011-09-16 | 2011-09-16 | 奥沙拉秦钠的制备方法和甲磺化反应的后处理方法 |
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CN102531955A CN102531955A (zh) | 2012-07-04 |
CN102531955B true CN102531955B (zh) | 2014-02-19 |
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Families Citing this family (3)
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PL3200827T3 (pl) | 2014-10-03 | 2020-12-14 | Xellia Pharmaceuticals Aps | Kompozycje |
US11033602B2 (en) | 2014-10-03 | 2021-06-15 | Xellia Pharmaceuticals Aps | Inhalation device |
CN107698459A (zh) * | 2017-10-30 | 2018-02-16 | 上海泰坦科技股份有限公司 | 一种奥沙拉秦钠及其制备方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101085803A (zh) * | 2006-06-07 | 2007-12-12 | 上海医药工业研究院 | 一类雄甾化合物及其制备方法和用途 |
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101085803A (zh) * | 2006-06-07 | 2007-12-12 | 上海医药工业研究院 | 一类雄甾化合物及其制备方法和用途 |
Non-Patent Citations (2)
Title |
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奥沙拉秦的合成实验研究;张玮等;《河北化工》;20071231;第30卷(第12期);"实验过程"部分 * |
张玮等.奥沙拉秦的合成实验研究.《河北化工》.2007,第30卷(第12期),"实验过程"部分. |
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