BR112016029266A2 - sistemas de catalisador para polimerização de olefinas - Google Patents

sistemas de catalisador para polimerização de olefinas

Info

Publication number
BR112016029266A2
BR112016029266A2 BR112016029266A BR112016029266A BR112016029266A2 BR 112016029266 A2 BR112016029266 A2 BR 112016029266A2 BR 112016029266 A BR112016029266 A BR 112016029266A BR 112016029266 A BR112016029266 A BR 112016029266A BR 112016029266 A2 BR112016029266 A2 BR 112016029266A2
Authority
BR
Brazil
Prior art keywords
olefin polymerization
catalyst systems
procatalyst
formula
metal
Prior art date
Application number
BR112016029266A
Other languages
English (en)
Other versions
BR112016029266B1 (pt
Inventor
J Young Andrew
N Iverson Carl
Szuromi Endre
Klosin Jerzy
P Fontaine Philip
Figueroa Ruth
G Brown Susan
T Rickaway Zach
Original Assignee
Dow Global Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Global Technologies Llc filed Critical Dow Global Technologies Llc
Publication of BR112016029266A2 publication Critical patent/BR112016029266A2/pt
Publication of BR112016029266B1 publication Critical patent/BR112016029266B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F4/00—Polymerisation catalysts
    • C08F4/42—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors
    • C08F4/44—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides
    • C08F4/60—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides together with refractory metals, iron group metals, platinum group metals, manganese, rhenium technetium or compounds thereof
    • C08F4/62—Refractory metals or compounds thereof
    • C08F4/64—Titanium, zirconium, hafnium or compounds thereof
    • C08F4/64003—Titanium, zirconium, hafnium or compounds thereof the metallic compound containing a multidentate ligand, i.e. a ligand capable of donating two or more pairs of electrons to form a coordinate or ionic bond
    • C08F4/64168—Tetra- or multi-dentate ligand
    • C08F4/64186—Dianionic ligand
    • C08F4/64193—OOOO
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/22—Organic complexes
    • B01J31/2204—Organic complexes the ligands containing oxygen or sulfur as complexing atoms
    • B01J31/2208—Oxygen, e.g. acetylacetonates
    • B01J31/2226—Anionic ligands, i.e. the overall ligand carries at least one formal negative charge
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/28—Titanium compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F210/00—Copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
    • C08F210/16—Copolymers of ethene with alpha-alkenes, e.g. EP rubbers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F4/00—Polymerisation catalysts
    • C08F4/42—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors
    • C08F4/44—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides
    • C08F4/60—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides together with refractory metals, iron group metals, platinum group metals, manganese, rhenium technetium or compounds thereof
    • C08F4/62—Refractory metals or compounds thereof
    • C08F4/64—Titanium, zirconium, hafnium or compounds thereof
    • C08F4/659—Component covered by group C08F4/64 containing a transition metal-carbon bond
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F4/00—Polymerisation catalysts
    • C08F4/42—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors
    • C08F4/44—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides
    • C08F4/60—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides together with refractory metals, iron group metals, platinum group metals, manganese, rhenium technetium or compounds thereof
    • C08F4/62—Refractory metals or compounds thereof
    • C08F4/64—Titanium, zirconium, hafnium or compounds thereof
    • C08F4/659—Component covered by group C08F4/64 containing a transition metal-carbon bond
    • C08F4/65908—Component covered by group C08F4/64 containing a transition metal-carbon bond in combination with an ionising compound other than alumoxane, e.g. (C6F5)4B-X+
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F4/00—Polymerisation catalysts
    • C08F4/42—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors
    • C08F4/44—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides
    • C08F4/60—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides together with refractory metals, iron group metals, platinum group metals, manganese, rhenium technetium or compounds thereof
    • C08F4/62—Refractory metals or compounds thereof
    • C08F4/64—Titanium, zirconium, hafnium or compounds thereof
    • C08F4/659—Component covered by group C08F4/64 containing a transition metal-carbon bond
    • C08F4/65912—Component covered by group C08F4/64 containing a transition metal-carbon bond in combination with an organoaluminium compound
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

a presente invenção fornece um pró-catalisador que compreende um complexo de metal-ligante de fórmula (i):(fórmula i), em que m, x, n, cada z, l, r21, r22 e r1 a r20 são, cada um, aqui descritos.
BR112016029266-9A 2014-06-30 2015-06-29 Pré-catalisador BR112016029266B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462018841P 2014-06-30 2014-06-30
US62/018,841 2014-06-30
PCT/US2015/038269 WO2016003878A1 (en) 2014-06-30 2015-06-29 Catalyst systems for olefin polymerization

Publications (2)

Publication Number Publication Date
BR112016029266A2 true BR112016029266A2 (pt) 2017-08-22
BR112016029266B1 BR112016029266B1 (pt) 2021-11-30

Family

ID=53540890

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016029266-9A BR112016029266B1 (pt) 2014-06-30 2015-06-29 Pré-catalisador

Country Status (9)

Country Link
US (1) US10526431B2 (pt)
EP (2) EP3647314B1 (pt)
JP (2) JP6985015B2 (pt)
KR (1) KR102436873B1 (pt)
CN (1) CN106459286B (pt)
BR (1) BR112016029266B1 (pt)
ES (2) ES2949011T3 (pt)
SG (1) SG11201610694PA (pt)
WO (1) WO2016003878A1 (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201610690VA (en) * 2014-06-30 2017-01-27 Dow Global Technologies Llc Ethylene-based polymers
JP2016188204A (ja) * 2015-03-27 2016-11-04 三井化学株式会社 遷移金属化合物、該化合物を含むオレフィン多量化用触媒および該触媒存在下で行うオレフィン多量体の製造方法
US10450394B2 (en) * 2015-03-31 2019-10-22 Dow Global Technologies Llc Processes for the production of high molecular weight ethylene/alpha-olefin/non-conjugated interpolymers with low levels of long chain branching
WO2017206008A1 (en) 2016-05-30 2017-12-07 Dow Global Technologies Llc Ethylene/alpha-olefin/diene interpolymer
WO2017206009A1 (en) 2016-05-30 2017-12-07 Dow Global Technologies Llc Ethylene/alpha-olefin/diene interpolymers compositions
EP4029886A3 (en) * 2016-06-30 2022-09-28 Dow Global Technologies LLC Ethylene/alpha-olefin/polyene interpolymers and compositions containing the same
US10221260B2 (en) 2016-07-29 2019-03-05 Exxonmobil Chemical Patents Inc. Phenolate transition metal complexes, production and use thereof
SG11201900653RA (en) * 2016-07-29 2019-02-27 Dow Global Technologies Llc Silyl-bridged bis-biphenyl-phenoxy catalysts for olefin polymerization
WO2018022279A1 (en) 2016-07-29 2018-02-01 Exxonmobil Chemical Patents Inc. Phenolate transition metal complexes, production and use thereof
US11008412B2 (en) 2016-09-29 2021-05-18 Dow Global Technologies Llc Method of polymerizing an olefin
KR102449474B1 (ko) 2016-09-29 2022-10-11 다우 글로벌 테크놀로지스 엘엘씨 마그네슘 할라이드-담지 티탄 (전)촉매
US11091572B2 (en) 2016-09-29 2021-08-17 Dow Global Technologies Llc Modified Ziegler-Natta (pro) catalysts and system
ES2843731T3 (es) 2016-10-27 2021-07-20 Univation Tech Llc Método de preparación de un catalizador molecular
BR112019020417B1 (pt) 2017-03-31 2023-04-04 Dow Global Technologies Llc Sistema catalisador e processo de polimerização para produzir um polímero à base de etileno
WO2018183056A1 (en) * 2017-03-31 2018-10-04 Dow Global Technologies Llc Germanium-bridged bis-biphenyl-phenoxy catalysts for olefin polymerization
ES2951157T3 (es) * 2017-09-29 2023-10-18 Dow Global Technologies Llc Catalizadores de bis-fenil fenoxi poliolefina que tienen un ligando alcoxi o amido en el metal para obtener una solubilidad mejorada
KR102100142B1 (ko) * 2017-12-21 2020-04-14 사빅 에스케이 넥슬렌 컴퍼니 피티이 엘티디 금속-리간드 착체, 이를 포함하는 에틸렌계 중합용 촉매 조성물 및 이를 이용한 에틸렌계 중합체의 제조방법
BR112020025521A2 (pt) 2018-06-15 2021-03-09 Dow Global Technologies Llc Filme soprado
WO2019241517A1 (en) 2018-06-15 2019-12-19 Dow Global Technologies Llc Cast films comprising bimodal ethylene-based polymers having high molecular weight high density fractions
SG11202012176XA (en) 2018-06-15 2021-01-28 Dow Global Technologies Llc Process for the production of bimodal ethylene-based polymers having high molecular weight high density fractions
WO2021133613A1 (en) * 2019-12-26 2021-07-01 Dow Global Technologies Llc Process for the production of polymer compositions with excellent processability
US20230133760A1 (en) 2020-01-31 2023-05-04 Dow Global Technologies Llc Group iii and lanthanide bis-phenyl-phenoxy metal-ligand complexes
CA3180273A1 (en) * 2020-05-29 2021-12-02 Rhett A. BAILLIE Catalyst systems and processes for producing polyethylene using the same
KR20230039687A (ko) 2020-07-17 2023-03-21 다우 글로벌 테크놀로지스 엘엘씨 비스-페닐페녹시 금속-리간드 착물을 위한 히드로카르빌-개질된 메틸알루미녹산 공촉매
CN116234834A (zh) 2020-07-17 2023-06-06 陶氏环球技术有限责任公司 双苯基苯氧基金属-配体络合物的烃基改性甲基铝氧烷助催化剂
JP2023541768A (ja) 2020-07-17 2023-10-04 ダウ グローバル テクノロジーズ エルエルシー ビス－フェニルフェノキシ金属－配位子錯体のためのヒドロカルビル修飾メチルアルミノキサン共触媒
US11667590B2 (en) * 2021-05-26 2023-06-06 Chevron Phillips Chemical Company, Lp Ethylene oligomerization processes

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153157A (en) 1987-01-30 1992-10-06 Exxon Chemical Patents Inc. Catalyst system of enhanced productivity
US7163907B1 (en) 1987-01-30 2007-01-16 Exxonmobil Chemical Patents Inc. Aluminum-free monocyclopentadienyl metallocene catalysts for olefin polymerization
US5064802A (en) 1989-09-14 1991-11-12 The Dow Chemical Company Metal complex compounds
JP2545006B2 (ja) 1990-07-03 1996-10-16 ザ ダウ ケミカル カンパニー 付加重合触媒
US5721185A (en) 1991-06-24 1998-02-24 The Dow Chemical Company Homogeneous olefin polymerization catalyst by abstraction with lewis acids
US5296433A (en) 1992-04-14 1994-03-22 Minnesota Mining And Manufacturing Company Tris(pentafluorophenyl)borane complexes and catalysts derived therefrom
US5350723A (en) 1992-05-15 1994-09-27 The Dow Chemical Company Process for preparation of monocyclopentadienyl metal complex compounds and method of use
US5372682A (en) 1993-06-24 1994-12-13 The Dow Chemical Company Electrochemical preparation of addition polymerization catalysts
US5625087A (en) 1994-09-12 1997-04-29 The Dow Chemical Company Silylium cationic polymerization activators for metallocene complexes
US5883204A (en) 1996-03-27 1999-03-16 The Dow Chemical Company Solution polymerization process with dispersed catalyst activator
EP0889912B1 (en) 1996-03-27 2000-07-12 The Dow Chemical Company Highly soluble olefin polymerization catalyst activator
US5783512A (en) 1996-12-18 1998-07-21 The Dow Chemical Company Catalyst component dispersion comprising an ionic compound and solid addition polymerization catalysts containing the same
US6103657A (en) 1997-07-02 2000-08-15 Union Carbide Chemicals & Plastics Technology Corporation Catalyst for the production of olefin polymers
US6696379B1 (en) 1997-09-19 2004-02-24 The Dow Chemical Company Supported modified alumoxane catalyst activator
CN1495188A (zh) 1999-12-10 2004-05-12 取代的第4族金属配合物，催化剂和烯烃聚合方法
US7091292B2 (en) 2002-04-24 2006-08-15 Symyx Technologies, Inc. Bridged bi-aromatic catalysts, complexes, and methods of using the same
WO2004046214A2 (en) 2002-10-15 2004-06-03 Exxonmobil Chemical Patents Inc. Multiple catalyst system for olefin polymerization and polymers produced therefrom
JP4879882B2 (ja) 2004-03-17 2012-02-22 ダウ グローバル テクノロジーズ エルエルシー より高次のオレフィンマルチブロックコポリマーを形成するためのシャトリング剤を含む触媒組成物
EP1751169B1 (en) 2004-04-29 2016-04-13 Symyx Solutions, Inc. Bridged bi-aromatic catalysts, complexes, and method of using the same
DE102004030714A1 (de) 2004-06-25 2006-01-12 Clariant Gmbh Schmelzklebemassen
AR060643A1 (es) * 2006-05-17 2008-07-02 Dow Global Technologies Inc Proceso de polimerizacion de solucion de polipropileno
US8802797B2 (en) * 2008-06-20 2014-08-12 Exxonmobil Chemical Patents Inc. Vinyl-terminated macromonomer oligomerization
MX350592B (es) 2010-05-17 2017-09-11 Dow Global Tech Llc * Proceso para polimerizacion selectiva de etileno y un catalizador del mismo.
US8785554B2 (en) 2010-06-21 2014-07-22 Dow Global Technologies Llc Crystalline block composites as compatibilizers
KR20130124171A (ko) 2010-07-06 2013-11-13 티코나 게엠베하 고 분자량 폴리에틸렌의 제조 방법
BR112012032745A2 (pt) * 2010-07-06 2016-11-08 Ticona Gmbh processo para produção de polietileno de alto peso molecular
CN102958957B (zh) 2010-07-06 2015-09-02 提克纳有限公司 产生高分子量聚乙烯的方法
ES2638071T3 (es) 2010-07-27 2017-10-18 Henkel Ag & Co. Kgaa Procedimiento para la fabricación de un adhesivo por medios de extrusión
BR112013003706A2 (pt) 2010-08-25 2016-08-16 Dow Global Technologies Llc processo para copolimerizar olefinas polimerizáveis, complexo de ligante-metal, catalisador e ligante
KR101702317B1 (ko) 2010-11-19 2017-02-03 헨켈 아이피 앤드 홀딩 게엠베하 접착제 조성물 및 이의 용도
WO2012069428A1 (en) 2010-11-22 2012-05-31 Noscira, S.A. Bipyridine sulfonamide derivatives for the treatment of neurodegenerative diseases or conditions
WO2012071459A1 (en) 2010-11-22 2012-05-31 The Regents Of The University Of California New indication for use of niacin (nicotinic acid) for treatment, prevention and reversal of fatty liver disease
US9469791B2 (en) 2011-04-28 2016-10-18 Adherent Laboratories, Inc. Polyolefin based hot melt adhesive composition
ES2617728T3 (es) 2012-09-14 2017-06-19 Dow Global Technologies Llc Películas de multicapa basadas en poliolefina
KR102133068B1 (ko) 2012-10-09 2020-07-10 다우 글로벌 테크놀로지스 엘엘씨 실란트 조성물
JP6797694B6 (ja) * 2014-06-30 2021-01-20 ダウ グローバル テクノロジーズ エルエルシー オレフィン重合のためのプロセス
SG11201610690VA (en) 2014-06-30 2017-01-27 Dow Global Technologies Llc Ethylene-based polymers

Also Published As

Publication number Publication date
CN106459286B (zh) 2021-07-16
EP3160973A1 (en) 2017-05-03
BR112016029266B1 (pt) 2021-11-30
CN106459286A (zh) 2017-02-22
WO2016003878A1 (en) 2016-01-07
EP3647314B1 (en) 2023-05-24
KR20170028364A (ko) 2017-03-13
US10526431B2 (en) 2020-01-07
JP6999742B2 (ja) 2022-01-19
ES2796870T3 (es) 2020-11-30
JP6985015B2 (ja) 2021-12-22
KR102436873B1 (ko) 2022-08-26
JP2020158771A (ja) 2020-10-01
EP3647314A1 (en) 2020-05-06
US20170101493A1 (en) 2017-04-13
EP3160973B1 (en) 2020-04-08
SG11201610694PA (en) 2017-01-27
ES2949011T3 (es) 2023-09-25
JP2017520548A (ja) 2017-07-27

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