BR112016002979A8 - processo para a purificação de um composto de diaminofenotiazínio, processo para a purificação de azul de metileno e uso de um complexo de diaminofenotiazínio estabilizado protonado - Google Patents
processo para a purificação de um composto de diaminofenotiazínio, processo para a purificação de azul de metileno e uso de um complexo de diaminofenotiazínio estabilizado protonado Download PDFInfo
- Publication number
- BR112016002979A8 BR112016002979A8 BR112016002979A BR112016002979A BR112016002979A8 BR 112016002979 A8 BR112016002979 A8 BR 112016002979A8 BR 112016002979 A BR112016002979 A BR 112016002979A BR 112016002979 A BR112016002979 A BR 112016002979A BR 112016002979 A8 BR112016002979 A8 BR 112016002979A8
- Authority
- BR
- Brazil
- Prior art keywords
- purification
- diaminophenothiazine
- complex
- compound
- protonated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/20—[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epidemiology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Physics & Mathematics (AREA)
- Biodiversity & Conservation Biology (AREA)
- Optics & Photonics (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013903099A AU2013903099A0 (en) | 2013-08-15 | Purification method and compounds | |
| PCT/AU2014/000807 WO2015021500A1 (en) | 2013-08-15 | 2014-08-15 | Process for the purification of diaminophenothiazinium compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112016002979A8 true BR112016002979A8 (pt) | 2020-02-04 |
Family
ID=52467850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112016002979A BR112016002979A8 (pt) | 2013-08-15 | 2014-08-15 | processo para a purificação de um composto de diaminofenotiazínio, processo para a purificação de azul de metileno e uso de um complexo de diaminofenotiazínio estabilizado protonado |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9701648B2 (enExample) |
| EP (1) | EP3033331B1 (enExample) |
| JP (1) | JP6111381B2 (enExample) |
| KR (1) | KR101741235B1 (enExample) |
| CN (1) | CN105612148B (enExample) |
| BR (1) | BR112016002979A8 (enExample) |
| CA (1) | CA2920505C (enExample) |
| DK (1) | DK3033331T3 (enExample) |
| IL (1) | IL243937A (enExample) |
| MX (1) | MX354492B (enExample) |
| NZ (1) | NZ630569A (enExample) |
| SG (1) | SG11201601003PA (enExample) |
| TW (1) | TWI629267B (enExample) |
| WO (1) | WO2015021500A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3375777A1 (en) * | 2017-03-15 | 2018-09-19 | MIKROCHEM spol. s.r.o. | Method for preparation of 3,7-bis-(dimethylamino)-phenothiazin-5-ium chloride or bromide |
| CN112358475B (zh) * | 2020-11-30 | 2022-09-06 | 西北师范大学 | 一种苯并吡喃鎓-吩噻嗪衍生物及其制备方法和应用 |
| WO2023202464A1 (zh) * | 2022-04-19 | 2023-10-26 | 英科隆生物技术（杭州）有限公司 | 一种电子媒介体的提纯方法 |
| CN116947783A (zh) * | 2022-04-19 | 2023-10-27 | 英科隆生物技术（杭州）有限公司 | 一种电子媒介体的提纯方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909520A (en) | 1959-10-20 | Process for making acylated | ||
| DE1886C (de) | 1877-12-15 | 1877-12-15 | Basf Ag | Verfahren zur darstellung blauer farbstoffe aus dimethylanilin und anderen tertiaeren aromatischen monaminen |
| GB1293757A (en) | 1968-10-22 | 1972-10-25 | Paines & Byrne Ltd | A nerve stain composition |
| GB0327672D0 (en) * | 2003-11-28 | 2003-12-31 | Photopharmica Ltd | Developments in biologically active methylene blue derivatives (phenothiazines) |
| WO2005054217A1 (en) * | 2003-11-28 | 2005-06-16 | Photopharmica Limited | Developments in biologically active methylene blue derivatives (2) |
| PT2322517T (pt) | 2004-09-23 | 2019-07-30 | Wista Lab Ltd | Métodos de síntese química e purificação de compostos de diaminofenotiazínio incluindo cloreto de metiltionínio (mtc) |
| JP5186212B2 (ja) * | 2004-09-23 | 2013-04-17 | ウィスタ ラボラトリーズ リミテッド | メチルチオニニウム塩化物（ｍｔｃ）などのジアミノフェノチアジニウム化合物を化学合成および精製する方法 |
| AU2007274057B2 (en) * | 2006-07-11 | 2012-12-13 | TauRx Therapeutics Management Ltd | Methods of synthesis and/or purification of diaminophenothiazinium compounds |
| FR2903696B1 (fr) | 2006-07-12 | 2011-02-11 | Provence Technologies | Procede de purification de composes diaminophenothiazium |
| JP5898701B2 (ja) * | 2011-02-11 | 2016-04-13 | ウィスタ ラボラトリーズ リミテッド | フェノチアジンジアミニウム塩およびそれらの使用 |
-
2014
- 2014-08-15 TW TW103128051A patent/TWI629267B/zh not_active IP Right Cessation
- 2014-08-15 KR KR1020167005820A patent/KR101741235B1/ko not_active Expired - Fee Related
- 2014-08-15 BR BR112016002979A patent/BR112016002979A8/pt not_active Application Discontinuation
- 2014-08-15 CA CA2920505A patent/CA2920505C/en active Active
- 2014-08-15 US US14/911,813 patent/US9701648B2/en not_active Expired - Fee Related
- 2014-08-15 NZ NZ630569A patent/NZ630569A/en not_active IP Right Cessation
- 2014-08-15 CN CN201480055983.7A patent/CN105612148B/zh not_active Expired - Fee Related
- 2014-08-15 EP EP14836833.5A patent/EP3033331B1/en active Active
- 2014-08-15 WO PCT/AU2014/000807 patent/WO2015021500A1/en not_active Ceased
- 2014-08-15 DK DK14836833.5T patent/DK3033331T3/da active
- 2014-08-15 SG SG11201601003PA patent/SG11201601003PA/en unknown
- 2014-08-15 JP JP2016533750A patent/JP6111381B2/ja active Active
- 2014-08-15 MX MX2016002085A patent/MX354492B/es active IP Right Grant
-
2016
- 2016-02-03 IL IL243937A patent/IL243937A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2920505C (en) | 2018-04-03 |
| TW201527287A (zh) | 2015-07-16 |
| EP3033331A1 (en) | 2016-06-22 |
| IL243937A0 (en) | 2016-04-21 |
| NZ630569A (en) | 2017-06-30 |
| SG11201601003PA (en) | 2016-03-30 |
| MX354492B (es) | 2018-03-07 |
| MX2016002085A (es) | 2016-06-23 |
| AU2014306354A1 (en) | 2016-02-18 |
| KR20160042929A (ko) | 2016-04-20 |
| US20160200696A1 (en) | 2016-07-14 |
| JP2016528237A (ja) | 2016-09-15 |
| IL243937A (en) | 2017-01-31 |
| WO2015021500A1 (en) | 2015-02-19 |
| EP3033331A4 (en) | 2017-01-18 |
| TWI629267B (zh) | 2018-07-11 |
| CN105612148B (zh) | 2018-09-14 |
| US9701648B2 (en) | 2017-07-11 |
| DK3033331T3 (da) | 2018-04-30 |
| EP3033331B1 (en) | 2018-02-21 |
| JP6111381B2 (ja) | 2017-04-05 |
| CN105612148A (zh) | 2016-05-25 |
| CA2920505A1 (en) | 2015-02-19 |
| KR101741235B1 (ko) | 2017-05-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |